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Name of Category Action Indication Contraindication Adverse Effects Nursing

Drug Responsibilities
Oxytocin Hormone/Oxyto Synthetic form of •Antepartum: To •Contraindicated with •CV: Cardiac •History: Significant
xic endogenous hormone initiate or improve significant arrhythmias, PVCs, cephalopelvic
produced in the uterine contractions to cephalopelvic hypertension, disproportion,
Dosage: Adjust hypothalamus and achieve early vaginal disproportion, subarachnoid unfavorable fetal
dosage based stored in the posterior delivery; stimulation or unfavorable fetal hemorrhage positions or
on uterine pituitary; stimulates reinforcement of labor positions or •Fetal effects : Fetal presentations,
response the uterus, and in selected cases of presentations, bradycardia, neonatal severe toxemia,
causes myoepithelium uterine inertia; obstetric emergencies jaundice, low Apgar uterine inertia,
of the lacteal glands management of that favor surgical scores hypertonic uterine
to contract, which inevitable or intervention, • GI: Nausea, patterns, previous
results in milk incomplete abortion; prolonged use in vomiting caesarian section
ejection in lactating second trimester severe toxemia, • GU: Postpartum • Physical: FHR
women. abortion uterine inertia, hemorrhage, uterine (continuous
•Postpartum: To hypertonic uterine rupture, pelvic monitoring is
produce uterine patterns, induction or hematoma, uterine recommended);
contractions during augmentation of labor hypertonicity, spasm, fetal positions; fetal-
the third stage of labor when vaginal delivery tetanic contraction, pelvic proportions;
and to control is contraindicated, rupture of the uterus uterine tone; timing
postpartum bleeding previous caesarian with excessive and rate of
or hemorrhage section, dosage or contractions; breast
•Lactation deficiency pregnancy(nasal). hypersensitivity examination;
•Unlabeled use: To •Use cautiously with •Hypersensitivity: orientation, reflexes;
evaluate fetal distress renal impairment. Anaphylactic reaction P, BP, edema; R,
( oxytocin challenge • Other: Maternal and adventitious sounds;
test), treatment of fetal deaths when CBC, bleeding
breast engorgement used to induced labor studies, urinary
or in first or second output
stages of labor; •Health teachings
afibrogenemia;
severe water
intoxication with
seizures and coma,
maternal death
(associated with slow
oxytocin infusion over
24 hr; oxytocin has
antidiuretic effects)
Name of Category Action Indication Contraindication Adverse Effects Nursing
Drug Responsibilities

Polymyxin B Antibiotic Bactericidal: Has • Acute infections • Contraindicated •CNS: Neurotoxicity— •History: Allergy to
sulfate surfactant caused by susceptible with allergy to facial polymyxins, renal
(detergent) activity strains of polymyxins flushing,dizziness,drow disease, lactation
that allows it to Pseudomonas ( polymyxin B, siness, paresthesias • Physical: Site of
penetrate and disrupt aeruginosa, colistin, • Dermatologic : Rash, infection, skin color,
the cell membranes Haemophilus colistimethate). urticaria lesions; orientation,
of susceptible gram- influenza, Eschericia •Use cautiously with • GU: Nephrotoxicity reflexes speech; R;
negative bacteria, coli, Aerobacter renal disease, • Local: Pain at IM urinary output;
causing cell death; aerogenes, Klebsiella pregnancy, lactation injection site; urinalysis, serum
not effective against pneumonia when less thrombophlebitis at IV creatinine, renal
Proteus species. toxic drugs are injection sites; function tests
ineffective or irritation, burning, • Health teachings
contraindicated stinging, itching,
• Ophthalmic blurring of vision
preparations: (ophthalmic
Infections of the eye preparations)
caused by susceptible • Respiratory Apnea
strains of P. ( high dosage)
aeruginosa • Other: Drug
•Intrathecal: fever,superinfections
Meningeal infections
caused by P.
aeruginosa
Name of Category Action Indication Contraindication Adverse Effects Nursing
Drug Responsibilities
Name of Category Action Indication Contraindication Adverse Effects Nursing
Drug Responsibilities
Name of Category Action Indication Contraindication Adverse Effects Nursing
Drug Responsibilities
Name of Category Action Indication Contraindication Adverse Effects Nursing
Drug Responsibilities
Name of Category Action Indication Contraindication Adverse Effects Nursing
Drug Responsibilities
Pharmacologic
Sheet
Submitted By;
Aaron Joseph Diorico Uy, SN
BSN 2-C Group P
Submitted To:
Ms. Louradel Ulbata, RN
Clinical Instructor