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PROPOSED STRUCTURE FOR THEORY & PRACTICAL PAPERS WITH CONTACT HOURS PER WEEK AND CREDIT POINTS FOR BACHELOR IN PHARMACEUTICAL TEHCNOLOGY DEGREE (B. PHARMACY) SEMISTER-I A. THEORY SL. NO. L 1 2 HU 101 PT 101 M 103 3 PTB 101 HUMANITIES (Professional communication in English) PHARMACEUTICAL ANALYSIS REMEDIAL MATHEMATICS OR REMEDIAL BIOLOGY PHARMACEUTICAL CHEMISTRY 4 PT 103 (INORGANIC PHARMACEUTICAL CHEMISTRY) PHARMACEUTICS (DISPENSING PHARMACY) Total of Theory B. PRACTICAL 1 2 3 4 PT 191 PT 196 PT 193 PTB 191 PHARMACEUTICAL ANALYSIS Lab PHARMACEUTICS (DISPENSING PHARMACY) Lab PHARMACEUTICAL CHEMISTRY Lab REMEDIAL BIOLOGY Lab* Total of Practical Total of Semester 3 3 3 3 3 3 3 3 12 28 2 2 2 2 8 24 3 1 4 4 3 3 3 2 3 T 1 P TOTAL 3 3 3 3 CODE THEORY CONTACTS (PERIODS/WEEK) CREDITS

5

PT 106

3

-

-

3 16

3 16

* Note: PTB 191 is compulsory for all students * Practical examination is essential as per PCI norms : i) ii) Sessional Practical examination : 60 : 40

1

2

SEMESTER-II

A. THEORY Sl. No. L 1 2 3 4 5 6 PT 203 M 203 PT 204 HU202 PT 202 PT 205 PHARMACEUTICAL CHEMISTRY (PHYSICAL CHEMISTRY) ADVANCED MATEHMATICS & ENGINEERING MECHANICS PHARMACEUTICAL CHEMISTRY (ORGANIC CHEMISTRY) ENVIRONMENT & ECOLOGY PHARMACOGNOSY PHYSIOLOGY Total of Theory B. PRACTICAL 1 2 3 4 PT 293 PT 294 PT 292 PT 295 PHARMACEUTICAL CHEMISTRY (PHYSICAL CHEMISTRY) Lab PHARMACEUTICAL CHEMISTRY (ORGANIC CHEMISTRY) Lab PHARMACOGNOSY Lab PHYSIOLOGY Lab Total of Practical Total of Semester 3 3 3 3 3 3 3 3 12 33 2 2 2 2 8 29 3 3 3 3 2 2 CODE THEORY CONTACTS (PERIODS/WEEK) T 1 1 1 1 1 P TOTAL 4 4 4 3 3 3 21 4 4 4 3 3 3 21 CREDITS

2

3

SEMESTER-III

A. THEORY Sl. No. L 1 2 3 4 5 6 PT 304 PT 301 PT 306 PT 307 CS 303 PT-305 PHARMACEUTICAL CHEMISTRY (ORGANIC CHEMISTRY) PHARMACEUTICAL ANALYSIS PHARMACEUTICS (PHYSICAL PHARMACY) PHARMACEUTICAL ENGINEERING BASIC ELECTRONICS & COMPUTER APPLICATION Anatomy, Physiology & Health Education (APHE) Total of Theory B. PRACTICAL 1 2 3 4 5 PT 394 PT 391 PT 396 PT 397 CS 393 PHARMACEUTICAL CHEMISTRY (ORGANIC CHEMISTRY) Lab PHARMACEUTICAL ANALYSIS PHAMACEUTICS (PHYSICAL PHARMACY) Lab ENGINEERING DRAWING Lab BASIC ELECTRONICS & COMPUTER APPLICATION Lab Total of Practical Total of Semester 3 3 3 3 3 3 3 3 3 3 15 38 2 2 2 2 2 10 33 3 3 3 3 3 3 CODE THEORY CONTACTS (PERIODS/WEEK) T 1 1 1 1 1 P TOTAL 4 4 4 4 4 3 23 4 4 4 4 4 3 23 CREDITS

3

4

SEMESTER-IV

A. THEORY Sl. No. L 1 2 3 4 5 PT 406 PT 402 PT 404 PT 405 PT 407 PHARMACEUTICS (PHARMACEUTICAL TECHNOLOGY-I) PHARMACOGNOSY PHARMACEUTICAL CHEMISTRY (BIO-CHEMISTRY) PHYSIOLOGY PHARMACEUTICAL ENGINEERING 3 3 3 3 3 CODE THEORY CONTACTS (PERIODS/WEEK) T 1 1 1 1 1 P TOTAL 4 4 4 4 4 4 4 4 4 4 CREDITS

Total of Theory B. PRACTICAL 1 2 3 4 PT 496 PT 492 PT 497 PT 494 PHARMACEUTICS (PHARMACEUTICAL TECHNOLOGY-I) LAB PHARMACOGNOSY Lab PHARMACEUTICAL ENGINEERING LAB PHARMACEUTICAL CHEMISTRY (BIO-CHEMISTRY) LAB Total of Practical Total of Semester 3 3 3 3

20

20

3 3 3 3 12 32

2 2 2 2 8 28

4

THEORY Sl.5 SEMESTER-V A. No. L 1 2 3 PT 506 PT 508 PT 509 PHARMACEUTICS (PHARMACEUTICAL TECHNOLOGY-II) PHARMACOLOGY PHARMACEUTICAL MICROBIOLOGY PHARMACEUTICAL CHEMISTRY (MEDICINAL CHEMISTRY) 5 PT 507 PHARMACEUTICAL ENGINEERING PHARMACEUTICAL CHEMISTRY (BIO-CHEMISTRY) Total of Theory B. PT 504 3 - - 3 3 2 3 PT 597 PT 599 - - 3 3 3 3 2 2 4 PT 593 - - 3 3 2 5 . PRACTICAL 1 PT 596 PHARMACEUTICS (PHARMACEUTICAL TECHNOLOGY-II) LAB PHARMACEUTICAL ENGINEERING LAB PHARMACEUTICAL MICROBIOLOGY LAB PHARMACEUTICAL CHEMISTRY (MEDICINAL CHEMISTRY) LAB Total of Practical Total of Semester 12 32 08 28 3 3 2 20 20 3 3 3 3 3 3 CODE THEORY CONTACTS (PERIODS/WEEK) T 1 P TOTAL 4 3 3 4 3 3 CREDITS 4 PT 503 3 1 - 4 4 6.

No. PRACTICAL 1 PT 693 PHARMACEUTICAL CHEMISTRY (MEDICINAL CHEMISTRY) LAB PHARMACEUTICS (PHARMACEUTICAL TECHNOLOGY) LAB PHARMACUTICS 3 4 5 PT 697 PT 698 PT 691A/B (BIO-PHARMACEUTICS & PHARMACOKINETICS) LAB PHARMACOLOGY LAB ELECTIVE-I Total of Practical C. SESSIONALS Seminar (PT 682) Total of Semester Elective-I PT610A/691A: Computer application in Pharmaceutical Technology and in Clinical Pharmacy. PT 611 PT 608 PT 609 PT 610A/B (BIO-PHARMACEUTICS & PHARMACOKINETICS) PHARMACOLOGY PHARMACEUTICAL BIO-TECHNOLOGY & INDUSTRIAL MICRO-BIOLOGY ELECTIVE-I Total of Theory B. L 1 PT 603 PHARMACEUTICAL CHEMISTRY (MEDICINAL CHEMISTRY) 2 PT 606 PHARMACEUTICS (PHARMACEUTICAL TECHNOLOGY) PHARMACEUTICS 3 4 5 6. PT610B/691B: Advanced Pharmaceutical Biotechnology. 3 35 2 30 12 8 -3 3 3 3 2 2 3 3 2 3 3 3 3 1 4 3 3 3 20 4 3 3 3 20 3 3 3 3 CODE THEORY CONTACTS (PERIODS/WEEK) T 1 P TOTAL 4 4 CREDITS 2 PT 696 - - 3 3 2 6 . THEORY Sl.6 SEMESTER-VI A.

7 SEMESTER-VII A. SESSIONALS 1 Seminar on assigned topic (PT 782) Total of sessionals Total of Semester ElectivePT709A: Packaging Technology PT709B: Advanced Pharmacognosy. L 1 PT 706 PHARMACEUTICS (PHARMACEUTICAL TECHNOLOGY) PHARMACEUTICAL CHEMISTRY (MEDICINAL CHEMISTRY) PHARMACOGNOSY PHARMACOLOGY ELECTIVE-II 3 CODE THEORY CONTACTS (PERIODS/WEEK) T P TOTAL 3 3 CREDITS 2 3 4 5 PT 703 PT 702 PT 708 PT 709A/B/C 3 3 3 3 - - 3 3 3 3 15 3 3 3 3 15 Total of Theory B. 3 3 32 3 3 2 2 3 PT 793 PT 783 - - 3 8 3 8 14 2 6 10 2 2 27 7 . No. PT709C: Pharmaceutical Marketing Management. THEORY Sl. PRACTICAL 1 PT 796 PHARMACEUTICS (PHARMACEUTICAL TECHNOLOGY) LAB PHARMACEUTICAL CHEMISTRY (MEDICINAL CHEMISTRY) LAB PROJECT Total of Practical C.

Sessional 1 PT 884 VIVA-VOCE Total of Sessional Total of Semester 06 21 06 20 06 06 PRECIES OF TOTAL GRADES IN B.8 SEMESTER-VIII A. PRACTICAL 1 PT 891 PHARMACEUTICAL ANALYSIS Total of Practical 3 3 03 2 02 3 3 3 3 CODE THEORY CONTACTS (PERIODS/WEEK) T P TOTAL 3 3 3 3 12 3 3 3 3 12 CREDITS C. L 1 2 3 4 PT 812 PT 813 PT 818 PT 801 PHARMACEUTICAL INDUSTRIAL MANAGEMENT PHARMACEUTICAL JURISPRUDENCE & ETHICS HOSPITAL PHARMACY & CLINICAL PHARMACY PHARMACEUTICAL ANALYSIS Total of Theory B. No. PHARMACY PROGRAMME SEMESTER SEM I SEM II SEM III SEM IV SEM V SEM VI SEM VII SEM VIII TOTAL CREDIT MINIMUM MAXIMUM 24 29 33 28 28 30 27 20 219 8 . THEORY Sl.

intelligibility and reasonable fluency 9 . Keeping in view the requirements of his students . The teacher must function as a creative monitor in the class-room. The aim should be to enable the students to find out for himself the correct pronunciation of a word from a learner’s dictionary. language laboratory ) are not available. and speak reasonably clearly ( if not fluently ) on routine matters with his fellow students. Lecture classes must be conducted as lecturecum-tutorial classes. the teacher may have to prepare some teaching and exercise material. 4. intonation . THIS IS TO BE CONSIDERED AT THE TIME OF FINALISATION OF THE CURRICULUM. understand slowly-delivered spoken material in Standard Indian English . good tape recorders can be used if the more advanced facilities ( for example . 2. BIT. stress . THE TOTAL COURSE HAS BEEN DESIGNED ON THE BASIS OF AICTE & JADAVPUR UNIVERSITY.9 NOTE: PHARMACEUTICAL TECHNOLOGY IS A MULTI-DISCIPLINARY SUBJECT THAT’S WHY THE STRUCTURE GIVEN BY THE WEST BENGAL UNIVERSITY OF TECHNOLOGY HAS BEEN DEVIATED IN SOME POINTS. SYLLABUS FOR B. Plenty of exercises of various kinds must be done by the students both inside and outside the classroom. write reasonably grammatically understand ( if not use ) at least some 2500 general purpose words of English to express himself in writing and 1500 words to talk about day-to-day events and experiences of life. It is a course that aims to develop skills. 3. In teaching speaking. MESRA & PILANI COURSE STRUCTURE. The teacher must not depend on a single or a set of two or three text books. emphasis should be on clarity . etc. In fact they can be used very fruitfully. Minimum time should be spent in teaching phonetic symbols . PHARMACY SEMESTER-I PROFESSIONAL COMMUNICATION IN ENGLISH Code : HU 101 Contact : 2L + I T = 3 Credits: 3 Guidelines for Course Execution Objective of the Course To impart basic skills of communication in English through intensive practice to the first year UG students of Engineering so as to enable them to function confidently and effectively in that language in the professional sphere of their life. Desired Entry Behaviour The student must have some basic command of English that is must be able to : 1. It is therefore “practical” in orientation. Strategies for Course Execution • • • • • • • The topics must be conveyed through plenty of examples. For practice in listening . He must choose his materials from diverse sources.

interpersonal . expressing ideas within a restricted word limit. very fast ) . punctuation and spelling. reading between the lines. Telephonic Conversation. business letters. the introduction and the conclusion. Classroom presentation and group discussion sessions should be used to teach speaking. clarity and appropriateness in communication. context of communication. End Results from the Course Some Key Concepts Communication as sharing. informal and semiformal speaking . manipulating paralinguistic features of speaking ( voice quality . handling questions and taking in criticism of self. fast . classroom presentation. intelligent listening in institutions such as an interview in which one is a candidate. for discussion at a later stage . semantics of connectives.10 rather than on “ correct “ pronunciation of words. for relaxation . Speaking Achieving desired clarity and fluency . for information . reading different kinds of texts for different purposes (for example . use of charts.) . Listening Comprehension Achieving ability to comprehend material delivered at relatively fast speed. interpersonal . for instance. modifiers and modals. barriers to communication. the speaker / writer and the listener / reader. variety in sentences and paragraphs. Writing Selecting material for expository. tone . and argumentative pieces. informal and semiformal speaking. task-oriented .Structure of opening / concluding paragraphs – Body of the essay ( 7 lectures) Reading Comprehension – Global – Contextual – Inferential – Select passages from recommended text ( 8 lectures) 10 . being polite and firm. Group Discussion Use of persuasive strategies including some rhetorical devices ( for emphasizing . formal report. British English and American English . ) pausing for effectiveness while speaking . comprehending spoken material in Standard Indian English. Syllabus Details: Grammar – Structure of sentences – Active / Passive Voice – Direct / ( 5 lectures) Indirect Narration Essay – Descriptive – Comparative – Argumentative – Thesis statement. paragraph division. descriptive . pitch . graphs and tables . making a short . task-oriented. medium of communication. etc. brevity. Reading Comprehension Reading at various speeds ( slow . listing reference material. summarizing and abstracting . etc. use of body language. turn-taking strategies and effective intervention .

Tata McGraw Hill . Mixed indicators. Acid Base Titrations : Acid base concept. New Delhi . L. methods of expressing concentration. OUP . R. Mark MaCormack : “Communication” 2. 1992 6. 1994 5. Significant figures. Biodata. Precipitation Titrations : Precipitation reactions. Types of report – Practice Writing ( 8 lectures) Communication / Public Speaking skills . Neutralization curves. General Book Depot. Significance of quantitative analysis in quality control. Choice of indicators. Acid-base indicators. Selection of sample. Types of errors. Preliminaries and definitions. S R Inthira & V Saraswathi “ Enrich your English – a) Communication skills b) Academic skills “ Publisher CIEFL & OUP 4. primary and secondary standards.Curriculum Vitae (7 lectures) Report Writing – Structure . Buffer solutions. temperature and solvent upon the solubility of a precipitate. mercuric nitrate. and barium sulphate. New Delhi . Henderson-Hesselbach equation. Effect of acids.C. John Metchell “ How to write reports” 3. 2.11 Business Correspondence – Letter Writing – Formal. 1998. “All About Words” . Mohr’s method. Common Ion effect. Statistical treatment of small data sets. Solubility products. Precision and accuracy. Longman . pH. Hydrolysis of salts. Volhard’s method and Fajan’s method. Law of mass action. Polyprotic system. Different techniques of analysis. Ionization.Resume′. “Business Correspondence and Report Writing “ . Mean deviation. Indicators. Features of effective speech.Gartside . 3. Gay-Lussac method. Drafting. Sharma and K. verbal-nonverbal ( 7 lectures) Group discussion – principle – practice ( 6 lectures) References / Books: 1. Ionic product of water. “Longman Dictionary of Contemporary English” ( or ‘Oxford Advanced Learner’s Dictionary of Current English’ . 11 . Rules for retaining significant digits. Maxwell Nurnberg and Rosenblum Morris . Pitman . 7.Mohan . Argentometric titrations and titrations involving ammonium or potassium thiocyanate. Fundamentals of volumetric analysis. Polyamine and amino acid systems. “Model Business Letters” . strengths of acids and bases. 1995 Code : Contacts: Credits : PT 101 3 3 Pharmaceutical Analysis 1. London . Selection of solvents. Standard deviation. Theory of indicators.

1. inversion method. calcium as calcium oxalate and magnesium as magnesium sulphate. Measurement of electrode potential. Standardization of analytical weights and calibration of volumetric apparatus. sodium thiosulphate. They should have a clear understanding of a typical analytical balance. M 103 3L + IT Algebra: Determinants of order 2. evaluation of limits by L’ Hospital’s rule (Indeterminate form) 2. special types of matrices. some exercises related with determination of acids and bases separately or in mixture form . 5. Solubility products. methods of weighing and errors in weighing. iodine. aluminium as aluminium oxide. 3.3. Precipitation titrations: Preparation and standardization of titrants like silver nitrate and ammonium thiocyanate. some official assay procedures e. Thermogravimetric curves. Strengths and equivalent weights of oxidising and reducing agents. matrices. simple problems. 5. Leibnitz theorem (statement only) simple problems. Filteration. potassium permanganate Gravimetric analysis: Precipitation techniques. potassium permanganate. potassium iodate. Lagrange’s Mean Value Theorem. solution of simultaneous equations by matrices. The colloidal state. supersaturation co-precipitation.12 4. continuity of functions of a single variable derivatives. successive derivatives. weights. The students should also be acquainted with the general apparatus required in various analytical procedures. inverse of a matrix. Washing of the precipitate. Theory of redox titration. the requirements of a good balance. Oxidation Reduction Titrations: Preparation and standardization of some redox titrants e. simple problems.Ignition. properties. Titrations according to Volhard’s and Fajan’s method. 2. Gravimetric analysis: One exercise related to gravimetric analysis is to be covered. care and use of balance. Cell representations. etc. solution of simultaneous equations by Cramer’s rule. 4. Remedial Mathematics Theory Code: Contacts: Credits: 3 1. Redox indicators. Filter papers and crucibles. Redox reactions.g. Specific examples like barium sulphate. Iodometry and Iodimetric Titrations involving ceric sulphate.g. Post-precipitation. some exercises related to determination of oxidizing and reducing agents in the sample shall be covered. Acid base Titration: Preparation and standardization of acids and bases. boric acid should also be covered. pharmaceutical applications of determinants and matrices. oxidation-reduction curves. 12 . Calculus: Differential: Limits. Oxidation Reduction Titration: Concepts of oxidation and reduction. potassium bromate. Practical Code: Contacts: Credits: PT 191 3 2 The students should be introduced to the main analytical tools through demonstrations. potassium dichromate. arithmetic operations on matrices.

2. partial fractions. PTB 191 3 2 Morphology of plant parts indicated in theory. different types of plant tissues and their structure. General Survey of animal kingdom. housefly. OR Remedial Biology Theory Code: Contacts: Credits: 3 1. mites (sarcoptes scabies) and silkworm. Modification of root and stem. linear differential equations of order greater than one with constant coefficients. Preparation. stem. Morphology and histology of root. inflorescence flower. no proof) Maxima and minima for functions of a single variable. location and function. method of substitution. taxa and taxon Plant Cell : It’s structure and non-living inclusions. Eculer’s theorem on homogeneous functions of two variables (statement. plasmodium. microscopic examination of stem. Morphology of plant parts indicated in theory. taenia. 5. 4. exact and linear differential equations and equations reducible to such types. variable separable. 4. trypanosoma. brief idea about natural sexual and phyllogenetic system and classification. schistosom. bark. Dissection of toads and identification of different organs. mitosis and meiosis. binomial nomenclature. Structure and life history & pathogenecity of parasites as illustrated by amoeba. wood. 6. rules of priority. their merits & demerits. ascaris. fruit and seed.13 Partial differentiation for functions of two variables. 5. PTB 101 3 2. integration by parts. use and type of microscopes. General Structure and life history of insects like mosquito. 3. order and degree. Care. Calculus : Integral: Indefinite integrals of standard forms. complementary function and particular integral. oxyuris. Gross identification of slides of structure and life cycle of lower plants. Differential Equations: Definition and formation of differential equations. root and leaf of monocot and dicot plants. 3. Practical Code: Contacts: Credits: 1. and ancylostoma. leaf. animals mentioned in theory. 3. simple problems. ICBN. 4. formal evaluation of definite integrals. entamoeba. General idea about classification of plants. 13 . equations of first order and first degree. homogeneous. pharmaceutical applications.

hazards and precautions.14 Pharmaceutical Chemistry (Inorganic Pharmaceutical Chemistry) Theory Code: Contacts: Credits: 4 PT 103 3L + 1T An outline of methods of preparation. chlorinated lime. 5. zinc oxide) . clinical applications and dosage. Acids and Bases: Buffers :. physiological buffer. mineral supplements. excipients. Anti-oxidants. Electrolytes used for replacement therapy. sulphate and special tests if any. acid-base balance and combination therapy. Astringents and Anti-infectives(Hydrogen peroxide. characteristics. Water (Types. sedatives etc. filter aids. lead. arsenic. Inorganic Radio pharmaceuticals: Nuclear radio pharmaceuticals. calamine & calamine lotion. Cathartics (definition and Mechanism of action of cathartics. drug interaction. quality. colorants etc. selection of buffer solution and role of buffer in pharmacy. Arrhenius concept. Bronsted Lowry concept. sources of impurities. suspending agents. Cationic and anionic components of inorganic drugs useful for systemic effects. 9. potassium permanganate. 7. pH. poisons and antidotes. Topical Agents: Protectives (silicon polymers. iodine solutions. preservatives. 1. 8. Buffer solutions. sublime sulphur) Dental Products: Dentifices. milk of magnesia. identification tests for pharmaceutical/inorganic pharmaceuticals and qualitative tests for cations and anions should be covered. 4. uses. compounds including aluminium hydroxide gel. preferably by semi-micro methods. purification and preservation) Gastrointestinal Agents: Acidifying agents (dilute hydrochloric acid). Magnesium sulphate and disodium hydrogen phosphate) Major Intra-and Extra-cellular electrolytes: Physiological ions. magnesium trisilicate and sodium bi-carbonate injection] Protectives and Adsorbents (mismatch sub-carbonate and bismath subgalate). tests for purity and identity. Essential and Trace Elements: Transition elements and their compounds of pharmaceutical importance: Iron and haematinics. of the following classes of inorganic pharmaceuticals included in Indian Pharmacopoeia. dried aluminium hydroxide gel. heavy metals. emetics. activated dimethicone. including limit tests for iron. 6. 14 . chloride. Antacids [definition. expectorants. Anti-caries agents Complexing and chelating agents used in therapy Miscellaneous Agents: Definition and representative example of Sclerosing agents. magnesium carbonate (light & heavy). buffer capacity. laxatives and purgatives. diluents. adsorbents. pOH. Practicals Code: Contacts: Credits: 2 PT 193 3 The background and systematic qualitative analysis of inorganic mixtures of upto four radicals. 3. Six Mixtures to be analysed. calcium carbonate. 2. 10. Pharmaceutical Aids used in Pharmaceutical Industry. Lewis concept.

paste.15 Pharmaceutics (Dispensing and Community Pharmacy) Theory Code: Contacts: Credits: 3 1. correction thereof and dispensing of such prescriptions. Correction of incompatibilities. 5. alcohol dilution. 3. 2. Pharmaceutical calculations : Posology. Prescription : Handling of prescription. paints. calculation involving percentage solution. PT 106 2L + 1T = 3 5. Colloids Acids. conductance and its measurement. lotions. Identification of various types of incompatibilities in prescription. General dispensing procedures including labelling of dispensing products. legal requirement for establishment. calculation of doses for infants. partition coefficient. maintenance and drug store-dispensing of proprietary products. 4. adults and elderly patients. allegation method. powders. optical rotation. PT 196 3 Dispensing of prescription falling under the categories : Mixture. maintenance of records of retail and wholesale. suppositories. The Liquid State: Physical properties (surface tension. colligative properties. 7. Solutions: Ideal and real solutions. Community Pharmacy : Organisation and structure of retail and whole sale drug store-types of drug store and design. pka. pH. deviation from ideal behaviours and explanation. 4. viscosity. tablet triturates etc. source of errors in prescription. opthalmics. 6. solutions of gases in liquids. ointments. chemical and therapeutic incompatibilities. dipole moments and chemical constituents). care required in dispensing procedures including labelling of dispensed products. Debye Huckel theory. parachor. role of pharmacist in community health care and education. proof spirit. refractive index. tablet titurates. patient counselling. isotonicity adjustment. Incompatibilities : Physical. Practical Code: Contacts: Credits: 2 1. 2. buffers and buffering action. powders. emulsions. Introduction to pharmacopoeia and different types of pharmaceutical formulations ( definition ). 2. 3. solutions. SEMESTER -II Pharmaceutical Chemistry (Physical Chemistry) Theory Code: Contacts: Credits: 4 1st Half 1. etc. emulsions. liniments. PT 203 3L + 1T 15 . pills. bases and salts. ointments. Behaviour of Gases: Kinetic theory of gases. Principles involved and procedures adopted in dispensing of : Typical prescriptions like solution.

diagramatic representation of data. Thermodynamics: Thermochemistry. 5. 8. Langmuir theory of adsorption. total. characteristics of homogeneous and heterogeneous catalysis. Laplace Transforms : Definition. 4. Second law of Thermodynamics : Entropy. inverse Laplace transforms. independence of events. linear curve fitting by the method of least squares. Heat. 6. first and second order reactions. mean. simple problems of probability. 2-D and 3-D diagrams. coefficient of variation. Electrochemistry: electrolyte and non-electrolytes 9. 9. 16 .16 6. data collection. 2. To determine the rate constant of simple reaction Determination of partition co-efficient of drugs Experiments on adsorption and colorimetry Determination of transition temperature of a salt. Phase equilibria and phase rule. Determination of adsorption coefficient. data organisation. Work. Practical Code: Contacts: Credits: 2 1. classical and frequency definition of probability. 7. Enthalpy. acid-base and enzyme catalysis. 3. First law of thermodynamics : Energy. solution of ordinary simultaneous differential equations (in two variables). statistical reference. Determination of surface tension and viscosity of liquids Determination of acid-base. elements of Binomial and Poisson distributions. confidence (fiducial) limits. addition and multiplication theorems of probability (no proof required). applications of statistical concepts in Pharmaceutical Sciences. 2. concept of probability. Student’s and paired t-test and F-test. transforms of derivatives. Vant Hoff equation. pie. Adsorption : Freudlich and Gibbs adsorption isotherms. significant digits and rounding off numbers. simple measures of central tendency. median. Arrhenius equation. properties of linearity and shifting. theories of reaction kinetics. Zero. mode. transforms of elementary functions. 8. 7. Kurtosis and skewness. bar. deduction of important equations Clausius-calpeyron equation Helomrholtz equation. standard Deviation and standard error of means. Biometrics : Exact and approximate numbers. Chemical Kinetics: Moleculerity and order of reaction. Normal distribution curve and properties. conditional and compound probability. dissociation constant by pH meter Advanced Mathematics & Engineering Mechanics Theory Code: Contacts: Credits: 4 M 203 3L + 1T 1. complex reactions. PT 293 3 To determine the refractive index of given liquids To determine the specific rotation of sucrose at various concentration and determine the intrinsic rotation. correlation and regression lines. Bayes Theorem (statement) and application. Free Energy Net Work. simple measure of dispersion.

Preparation and Reactions of: Alcohols. optical activity. Friction. Structure. Ethers. Intramolecular forces. Concept of Aromaticity 2. Bond dissociation energy. power. Polarity of bonds. Bonding and Anbtibonding orbitals. Aldehydes and ketones. Reactions involving stereoisomers. reduction of nitrobenzene etc. the usual classification of organic compounds : 1. Pharmaceutical Chemistry (Organic Chemistry) Theory Code: Contacts: Credits: 4 PT 204 3L + 1T The subject of organic chemistry will be treated in its modern perspective keeping for the sake of conveniences. Amines. 4. Nomenclature. Alkynes. The students should be introduced to the various laboratory techniques. energy. Dienes. Alkenes. Structure. PT 294 3 2. Nomenclature. alkyl halides.) Identification of organic compounds and their derivatisation. through demonstrations involving synthesis of selected organic compounds (e. stereoisomerism. Hybrid orbitals. Polygon of forces. Intermolecular forces. volume (use of calculus) simple problems. Molecular orbital theory. Preparation and Reactions of Alkanes. components of the environment. Sliding friction (simple problems) Centre of gravity arc. Practicals Code: Contacts: Credits: 2 1. structure and physical properties. Introduction to the use of stereomodels. Atomic orbitals. Structure and Properties : Atomic structure. ENVIRONMENT AND ECOLOGY Code: HU 202 Contacts: 3L + 1 T = 4 Credits: 3 General Introduction . Stereochemistry: Isomerism and nomenclature and associated physicochemical properties. Epoxides. Motion under gravity. environmental degradation 17 . Molecular orbitals. equilibrium of concurrent forces. conservation of Energy. chiral reagents conformations. work. aspirin. 3. Cycloalknes. specification of configuration.g. area. chirality. Engineering Mechanics : Composition and resolution of forces. Carboxylic acids. Polarity of molecules. 3. p-bromoacetanilide. 5. Covalent bond.17 3.

“Introduction to Environmental Engineering and Science”. Kerosene) Water Pollution and Control Hydrosphere. IBH Publishing Code: PT 202 . Nebel . chemical constituents including tests wherever applicable and therapeutic efficacy of following categories of drugs.18 Ecology Elements of Ecology . effects. Noise Pollution Sources. climate. history and scope of pharmacognosy including indigenous system of medicine. weather . recovery and conversion methods. hazardous solid wastes ) . Odum . Contacts: Com. distribution. green house effect. Fennel. 4. “Environmental Science”. Astringents – Catechu 18 . . 1991 2. Carminatives & G. Ltd. depletion of ozone layer. Ispaghula. 1987 3. Benzene. Noxious gases and vapours (CO.. Masters. commercial. standards and control. collection and disposal of solid waste. B. E. Definition.. Clove. energy balance. Ajowan. G. Cardamom. Various system of classification of drugs of natural origin.P. organoleptic evaluation. Nutmeg. References / Books: 1. natural water.M. standards and control measures. pollutants : their origin and effects . industrial. primary and secondary pollutants.I. 2. “Ecology: The Link between the Theory natural and social sciences” . Ecological balance and consequences of change. their origin and effects. 3 Delhi Credits: 3 1. significance of pharmacopoeial standards and different types of Extrinsic & Intrinsic factor. agricultural. Gasoline. 3. Cinnamon. principles of environmental impact assessment Air Pollution and Control Atmospheric composition. river / lake / ground water pollution. dispersion. regulators – Coriander. Prentice –Hall Pharmacognosy Inc. lead & mercury). a) b) c) d) Laxatives: Aloes. Castor oil..J. Rhuburb. Prentice –Hall of India Pvt. Senna Cardiotonics – Digitalis. Black pepper. sources and effects of pollutants . Adulteration and drug evaluation. Occurrence. standards and control (Specifically arsenic. microscopical evaluation.. Land Pollution Lithosphere . pollutants ( municipal.

292 3 Identification of crude drugs (containing carbohydrate. Respiratory system : 2. c) The blood volume. distribution. Cannabis. Cinamon bark. special junctional tissues of heart. The lymph and tissue fluids. b) The Erythrocytes. Electrocardiogram. Physical and chemical tests for evaluation of crude drugs wherever applicable Microscopic studies of Senna leaf. 3. Hemoglobin. composition and functions of blood. i) j) Antimalarials – Cinchona Oxytocics – Ergot k) Vitamins – Shark liver oil Practical Code: Contacts: Credits: 2 1. glycosides. a) Drugs acting on nervous system – Hyoscyamus. Nux vomica. b) Antihypertensives – Rauwolfia c) Antitussives – Vasaka. Occurrence. organoleptic evaluation. lipid. Aconite Ashwagandha. Cardiac cycle.Neem. chemical constituents including tests wherever applicable and therapeutic efficacy of following categories of drugs.) by morphological characters. Opium.19 5. alkaloid etc. Ephedra. Rauwolfia root. Belladonna. e) Cardiac muscle and its properties. 4. 19 . regulation of heart’s action. Physical characters. cardiac output. Identification of fibers and surgical dressings Physiology Theory Code: Contacts: Credits: 3 PT 205 3 1. leukocytes and platelets. Blood and cardiovascular system : a) The physiological properties. Tulsi d) Antirheumatics – Colchicum e) f) Antitumour – Vinca Antileprotics – Chaulmoogra Oil g) Antidysenterics – Ipecacuanha h) Antiseptics and disinfectants . volatile oil. 2. Hemolysis and suspension stability of the blood. Datura flower and stem. microscopical evaluation. d) The blood pressure.

pulse rate. b) Composition of Urine and the factors affecting the formation of urine. Electrophilic and nucleophilic aromatic substitution Synthesis and reaction of phenols. Experimental physiology : Handling. Hb. function & disorder Digestive system 4. 2. factors controlling the volume of urine. DC. 5. ESR. Nucleophillic aromatic substitutions: . Chemistry. chemistry of carbohydrate Polynuclear aromatic system : Heterocyclic Compounds : Nomenclature of heterocyclic compounds. Recording of body temperature.20 a) b) The mechanism of respiration. 20 . anaesthetising and injection of mice/rat/rabbit. PT 295 3 Study of human skeleton and identification of different visceral organs Study of different system with the help of charts and models. Anthracene. The control of respiration. blood pressure and brief understanding of ECGPQRST waves and their significance. Napthalene. the physical principles governing the respiratory exchanges. 4. Isotonic & isometric muscle contractions with special reference to temp. periodic respiration. numbering. 2. the carriage of carbon dioxide. anilines. 3. weighing. Microscopic studies of different tissues and organs Estimation of TC. Structure and Functions of kidney. clotting time.S. diazonium salt. 5. anoxia and other abnormal forms of respiration.6 atoms with one or two heteroatoms like O. bleeding time. renal circulation. Endocrine glands : Anatomical position. bioactive molecules SEMESTER – III Pharmaceutical Chemistry (Organic Chemistry) Theory Code: Contacts: Credits: 4 PT 304 3L + 1T = 4 1. Micturition. Functions of glomerulus. Intracellular oxidations and energy transfer. Practical Code: Contacts: Credits: 2 1. ion. 7.. 3. structure. nitro-compound. aromatic sulfonic acids. the air of the lungs. Functions of renal tubules. 6. etc. the transport and delivery of Oxygen to the tissues. c) Glycosuria.. preparations and properties of some important heterocyclis compounds containing 5.N. renal function tests. Excretory System : a) Renal circulation. dysponea.

Workshop on molecular modelling of different isomers.21 Practical Code: Contacts: Credits: 2 PT 394 3 At least two exercises in synthesis involving various heterocyclic ring systems. 5. Determination of alcohol content in liquid galenical. at least one exercise related to pharmacopoeial assays by complexometric titration. molecular modelling on double helical structure of nucleic acid showing hydrogen bonding. Conductometry 3. Oxygen flask combustion. 1. Complexometric titrations. Complexometric Titrations : Preparation and standardization of EDTA solution. Miscellaneous Methods of Analysis : Diazotisation titrations. 4. 4. Non-aqueous titrations 2. physiology and health education( APHE ) Theory Code: Contacts: Credits: 3 PT 305 2L + 1T = 3 21 . TLC. Paper Chromatography and Column Chromatography. Estimations of at least one pharmacopoeial product. GLC. Experiments involving separation of drugs from excipients and estimation. Potentiometry 2. Chromatography : The following techniques will be discussed with relevant examples of Pharmacopeial products. Amperometry 3. and application in drug analysis : 1. Karl-Fischer titration. HPLC. PT 391 3 2. At least 3 reactions involving eletrophilic aromatic substitutions. Miscellaneous Determinations : Exercises involving Karl-Fischer. Pharmaceutical Analysis Theory Code: Contacts: Credits: 4 PT 301 3L + 1T = 4 Theoretical considerations. 3. Anatomy. and application in drug analysis. Non aqueous Titrations : Preparation and standardization of perchloric acid and sodium/potassium/lithium methoxides solutions. Practical Code: Contacts: Credits: 2 1. Kjeldahl method of nitrogen estimation. Chromatographic analysis of some pharmaceutical products. Theoretical considerations.

5. relative humidity. mechanism of coagulation. spreading coefficient. optical microscopy. adsorption. Lymph and Lymphatic system: Composition. amorphous and polymorphism. 2. kinematic viscosity. a) Demography and family planning : Medical termination of pregnancy. blood groups and their significance. thixotropy in formulation. 4. complex films. number and weight distribution. Surface and Interfacial Phenomenon: Liquid interface. types of movements of joints. their causative agents. 22 . Elementary Tissues of the Human Body : Anatomical position. types. Basic physiology and functions of spleen. snake bites. composition and functions of skeleton. particle shape.22 1. bulkiness & flow properties. physiological properties of skeletal muscles and their disorders. malaria. solids-crystalline. measles. properties of colloids. muscular and nervous tissues. gonorrhoea and AIDS. tuberculosis. sublimation critical point. their disorders. settling in suspensions. Skeletal Muscles : Gross anatomy. average particle size. 4. surface active agents. Respiratory System : Anatomy of respiratory system and organs. plastic. Dispersion systems : Colloidal dispersions : Definition. sieving. Haemopoietic system : Composition and functions of blood and its elements. rabies. 5. liquid complexes. disorders of joints. non-Newtonian systems. influenza. gases. methods for determining particle volume. adsorption at liquid interfaces. physiology of muscle. tetanus. protective colloids. Micromeretics and Powder Rheology : Particle size and distribution. 3. effect of Brownian movement. aerosols-inhalers. Digestive System : General. 7. pseudoplastic. surface free energy. detergency. wetting of particles. 8. specific surface. packing arrangement. syphilis. Viscosity and Rheology : Newtonian systems. determination of viscosity. trachoma. rotational viscometers. densities. Matter. applications of colloids in pharmacy. theory of sedimentation. helminthiasis. electrical properties of interface. poisoning. b) Communicable diseases: Brief outline. porosity. structure. Classification of joints. Osseous System : Structure. HLB classification. 2. function of different parts including those of liver. 9. Latent heat and vapor pressure. Pharmaceutics (Physical Pharmacy) Theory Code: Contacts: Credits: 4 PT 306 3L + 1T = 4 1. connective. falling ball. dilatant. Law of flow. contraction. measurement of surface and interfacial tensions. liquid crystals. measurement. characteristic & functions of Epithelial. pancreas and gall bladder. adsorption at solid interfaces. sedimentation of flocculated particles. poliomyelitis. 3. effect of temperature. thixotropy. 6. disorders of lymph and lymphatic system. change in the state of matter. derived properties of powders. Eutectic mixtures. formulation and circulation of lymph. anatomical outline of gastrointestinal tract. disorders of platelets and coagulation. Suspensions and Emulsions: Interfacial properties of suspended particles. diphtheria. burns. d) First Aid : Emergency treatment of shock. leprosy. fractures and resuscitation methods. solid gas and solid-liquid interfaces. capillary. sedimentation parameters. solubilization. methods for determining surface area. surface and interfacial tensions. glassy state. c) Filariasis. permeability. Nervous System : General outline of central nervous system and autonomic nervous system. modes of transmission and prevention (Chicken pox. sedimentation. their sub-types. particle number. Properties of Matter : State of matter.

Fluid Flow : Different manometers and their application. molecular units. b) c) Gas handling-Various types of fans. compressibility. PT 307 3L + 1T = 4 2. Kinetics and Drug Stability : Half-life determination. material balance and related problems. different types of graphic representations. types of flow. Other solid transport systems. PT 396 3 5. flow measuring devices. 6. 9. physical stability. catalytic species and other factors. problems on stoichiometry. basic laws. mole fraction. The effect of pH of the solubility on a slightly soluble weak acid. Determination of surface/interfacial tension. expiration dating. 3. methods of preparation and analysis. 3. energy balance and related problems. evaluation of intrinsic viscosity of a system by viscosity determination using various concentration and if possible. analysis. blowers and compressors. Accelerated stability testing. 2. Preparation and stability studies of emulsions. flocculation in structured vehicles. light. Accelerated stability study. determination of molar mass Studies of different types of colloids and their properties. Influence of temperature. theories. rheological considerations. Bunkers. boundary layer concept. Complexation and Protein Binding : Classification of complexes. angle of repose etc. 4. d) Solid handling – Bins. Preparation of various types of suspensions and determination of their sedimentation parameters. Determination of derived properties of powders like density. Particle size distribution and surface area using various methods of Particle size analysis.23 6. binding equilibrium. Conveyers. Practicals Code: Contacts: Credits: 2 1. porosity. Study of rheological properties of various types of systems using different Viscometers. 8. Determination of particle size. Bernoulli’s theorem. Pharmaceutical Engineering Theory Code: Contacts: Credits: 4 1. applications. Dimensional analysis. non-Newtonian fluid flow – basic concept. Stoichiometry : Units and their conversions. shelf-life determination and expiration dating of pharmaceuticals. decomposition and stabilisation of medicinal agent. Thermodynamic treatment to stability constant. 7. 23 . Material Handling: a) Liquid handling – Different types of pumps. Emulsionstypes. controlled flocculation. solvent. Protein binding. Reynold’s number. HLB value and critical micellar concentration of surfactants. 7. fluid friction.

Basic concept of operating system and its functions. Computer Science and Applications Theory Code: Contacts: Credits: 4 1. artificial respiration etc. constants. Boolean Algebra: definition and rules.24 4. filter aids.2 1. classification. 5. Orthographic Projection – first and third angle concepts Isometric drawing and Dimensioning. Line drawing of agitator.3 1. Enumerated Data Types.4 1. simplification of logical expressions (K-Map not needed).5 24 . Data Variables. First Aid – shock. electrical. C Instructions and Rules for Writing Them Types of instructions Data Manipulation Instructions Input/Output Instructions Flow control instructions Decision Control Instructions If If-else 1. centrifugal filters and sedimentors. History of Computer development and respective generation: classification of computers. Alphabets in C Keywords in C. Industrial Hazards & Safety precautions : Different types of hazards like mechanical. saddle etc. truth tables. hardware and software. CS 303 3L + 1T Computers Applications : 1. logical expressions. NAND. Sections and Sectional Views Bolted and riveted joints Welded joints Pipe joints and fittings Types of flanges and working drawing of pulley. rotary filter. Basic Data types in C. tablet compressing machine etc. Engineering Drawing Code: Contacts: Credits: 2 PT 397 3 I. Centrifuge. fire etc. Principles of centrifugation. poison antidotes. scales etc. mathematical problems. Filtration and Centrifugation : Theory of filtration. Number system: Binary. dryer. Concept of flow diagram. Pressure vessel and auxiliaries – skirt. fainting. sieving machine. Pharmaceutical applications.1 Introduction to Computers. evaporator Calandria. OR NOT. chemical. XOR logic gates. granulator. Logic Gates: Introduction to logic gates. dust. Conventions of drawing – lettering. wounds. filter press edge filter etc. mixer. industrial filters like leaf filters. . Preventive methods and precautions. filter press. hexadecimal and octal number systems and their inter conversion. key etc. decimal.S. Data Types and Rules for naming and declaring data variables. different parts of modern digital computer and their functions. AND. ball mill. simple digital circuits using logic gates. NOR. 9MS-DOS commands will be learned and used in Laboratory only) Introduction to computer language. and resistances. Acid and Alkali burns.

Design and create a small inventory database. implement Foreign key and primary key constraints. creating and executing batch file.25 If-else-if Nested if-else Conditions Loop Control Instructions For loop While loop Do while Selection Instructions Functions Components of Function Name of a function Body of a function Local variables of a function Parameters of Arguments to a function Return Values Prototype of a function Arrays What is an array? Array Declaration Array Initialization Accessing individual elements of an array Two Dimensional Arrays Accessing the elements of a two dimensional array More than two dimensions Passing an array element to a function Simple programs using C Practical: [Code: CS 393] Contacts : 3 Credits : 2 1. Executing MS-DOS commands. update tables. 2. Create tables using Oracle. modify the structure of a table. Practical designed on the use of computers in drug information center. 25 . Design drug-drug interaction database. design and create a database of a small Hospital. retrieve different types of information using SQL. insert data into the tables. prescription filing and documentation of information on drug interaction. 3. writing and executing simple programs in C.

Pharmaceutical Aerosol : Mode of operation. Definition. 5. ointments. packaging. factors affecting extraction rate. podophyllum. PVP. 3. Lemon grass. clear gels manufacturing procedure. Dill. benzoin. 7. myrrh. contact lens solution. Study of volatile oils of Mentha. Sandal wood. 2. emulsifying agents. Citronella.26 SEMESTER – IV Pharmaceutics ( Pharmaceutical Technology-I ) Theory Code: Contact: Credits: 4 PT 406 3L + 1T = 4 1. formulation. Orange peel. Pharmacognosy Theory Code: Contacts: Credits: 4 1. suppositories. factors influencing penetration. eye ointments. silk. stability of suppositories. stabilization. Semisolid dosage forms: Definition. Cassia. eye drops. propellants. Fibers : Study of fibres used in pharmacy such as cotton. wool. emulsion. eye lotions. Tanins : Study of tannins and tannin containing drugs like Gambir. general formulation of semi-solids. Gaultheria. sterilization. turmeric. evaluation. Eye drops. Resins : Study of Drugs Containing Resins and Resin Combination like Colophony. colours. PT 496(1) 3P Preparation. dextran etc. types of additives used in formulation. polyester and asbestos. jalap. pharmaceutical application and testing. glass-wool. dry and soft liquid extracts. types. Extraction and Galenical Products : Principle and method of extraction. evaluation and packaging. mechanism of drug penetration. 4. preparation of infusion. Blood products and plasma substitutes : Collection. additives. solubilisers. type of bases. semi-solid bases and their selection. flavours and others. shape and doses. Musk. Caraway. suspension. evaluation and packaging of liquid orals like solution. eye ointments. 26 . Plasma substitutes – ideal requirements. Suppositories : Definition. gall and myrobalan. packaging. Ophthalmic preparation : Requirements. asafoetida. choice extraction procedure. Volatile Oils : General methods of obtaining volatile oils from plants. nylon. Chenopodium. tinctures. size. manufacturing and packaging methods. preparation. Eucalyptus. processing and storage of Whole human blood and all fractions individually.P. storage. factors affecting drug absorption. 3. Manufacturing. preservatives. Spearmint. Preparation of pharmacopoeal extracts and galenical products utilizing various methods of extraction. creams. Valerian. 4. ginger. for control of blood pressure as per I. capsicum. manufacturing procedure. suspending agents. Practical Code: Contacts: Credits: 2 1. Lemon peel. ideal requirements. balsam of peru. 2. balsam of tolu. cannabis. vehicles. packaging and evaluation. 6. container with all parts. PT 402 3L + 1T = 4 2. Liquid dosage forms : Introduction.

Ashoka. adulterants. 3. Practical Code: Contacts: Credits: 2 1. separation and purification of various groups of constituents present in crude drugs of pharmaceutical significance. 2. 7. Amphibolic role of the cycle. Shilajit. tannins and resins etc. chemical nature of chief constituents. Gluconeogenesis and glycogenolysis. enzymes and co-enzymes involved in oxidation reduction & its control. Chitrack. Asvas. Pharmaceutical aids : Study of pharmaceutical aids like talc. Study of the biological sources. Punarnava. The holistic concept of drug administration in traditional systems of medicine. identification. 8. Energetic of oxidative 27 .27 5. Glycolysis and fermentation and their regulation. chemical constituents. strophanthus and thervetia iii) Anthraquinone cathartics : cascara iv) Others : Psoralea. Enzymes : Nomenclature. PT 492 3 Microscopic study of powdered crude drugs containing volatile oil. Gokhru. Gutikas. gelatine and natural colours. steroids. Methi. Lahrun. Pharmaceutical Chemistry (Bio-chemistry) Theory Code: Contacts: Credits: 4 1. substitutes. 5. 8. Bhasmas. flavonoids. chirata. Tailas. commercial varieties. Tylophora. glycosides. Control of lipid metabolism. Role of sugar nuclectides in biosynthesis and Pentosephosphate pathway. diatomite. PT 404 3L + 1T = 4 7. sarsaparilla and senega ii) Cardioactive sterols : squill. Kantkari. Metals as co-enzymes and their significance. Bhilawa. Carbohydrate Metabolism : Conversion of polysaccharide to glucose – 1 – phosphate. Rasna. Transport processes across cell membrane. botanical sources. dioscorea. Metabolism of galactose and galactosemie. α-oxidation & energetic. quassia. and sphingolipids. 9. Ammi majus. Lehyas. Chemical tests for alkaloids. Studies of traditional drugs. 3. Arjuna. reactions and energetic of the cycle. Apamarg. Shankhapushpi. gentian. Satavari. Gyumnema. Churnas. Bach. 6. Palash. its role in energy capture and its control. 4. Production of ATP and its biological significance Introduction to 3D structure of protein. β-oxidation. mechanism of inhibition. Biosynthesis of ketone bodies and their utilization. Brahmi. The respiratory chain. enzyme kinetics and its mechanism of action. Guggal. enzymes and iso-enzymes in clinical diagnosis. The Citric Acid Cycle : Significance. Co-enzymes : Vitamins as co-enzymes and their significance. Common vernacular names. Ammi visnaga. Biological Oxidation : Redox-Potential. morphology. thromboxanes and leukotrienes) phospholipids. Lipids Metabolism : Oxidation of fatty acids. 2. Introduction to ayurvbedic preprations like Aristha. 6. bentonite. categories and common uses of following indigenous drugs : Amla. and Glyoxalic acid cycle. ω-oxidation. Biosynthesis of saturated and unsaturated fatty acids. uses. stability and denaturation of protein. kaolin. diagnostic macroscopic and microscopic features and specific chemical tests of following groups of drugs containing glycosides : i) Saponins: Ginseng. Essential fatty acids & eicosanoids (prostaglandins. pharmacology. allosteric proteins. glycosides. Laboratory experiments on isolation. alkaloids etc.

Heat Transfer : Heat transfer by conduction. sleep. PT 494 3 7. cerebrospinal fluid. Quantitative estimation of amino acids.. Reproductive system Pharmaceutical Engineering Theory Code: Contacts: Credits: 4 PT 407 3L + 1T = 4 1. forced convective and agitated film evaporators. 4. colorometric estimation of sugar. 3. cholesterol in blood. separation of lipids by TLC. Synapse Reflex arc. Receptor. heat transfer by radiation. estimation of SGOT. Stefan’s and Kirchoff’s Laws. non-protein N2 – in blood. Experiments on enzymes – effect of pH. Central nervous system : Nerve impulse. Experiments on lipids – saponification no. The spinal cord and brain stem. vision and hearing Body temperature and its regulation. 6. problems on convection. Cerebrum. Smell (alfaction). the thalamus and hypothalamus. 2. Factors affecting evaporation rate. Structure of autonomic ganglia. Condition reflex. different evaporators like short and long tubes. chromatographic separation of sugars. 4. reflex action. 2. Special sense : Taste (gustation). PT 405 3L + 1T = 4 2. Mathematical problems. effect of temperature and use of inhibitors. Evaporation : Principles of evaporation. Physiological mechanism governing the posture and equilibrium. pharmaceutical applications. Experiments on clinical bio-chemistry – blood glucose estimation. heat exchangers. 3.Autonomic nervous system : Classification. Experiments of sugar – test for reducing sugar. dual supply. problems on steady state heat conduction. 5. general arrangement and function of Sympathetic and parasympathetic system. Physiology Theory Code: Contacts: Credits: 4 1. iodine no. Mechanism of oxidative phosphorylation. Nervous system. organs. Inhibitors of respiratory chain and oxidative phosphorylation. protein. Multiple effect evaporation. Titration curve for amino acids Separation of amino acids by TLC method. heat transfer coefficient. separation of plasma proteins by paper electrophoresis. pharmaceutical applications.28 phosphorylation. general arrangement. drugs action on ANS. heat transfer by convection. Practical Code: Contacts: Credits: 2 1.. The extra-pyramidal system. SGPT and ALP in the serum. 28 . pyrexia and hypotherms.

Stoke’s Law. Cr. baby care products. size of capsules. agitated type and vacuum type etc. Fe. structure and function of skin and hair. Materials of construction: Introduction – Corrosion. evaluation of coated tablets. ceramics and different Ni. Capsules : Advantages and disadvantages of capsule dosage form. quality control. non-metals and alloys for fabrication. physics of tablets making. crystal growth etc. film coating. denitrifies and preparations like nail polish. c) Stability Kinetics and quality assurance. Tablets : a) Formulation of different types of tablets. important of base adsorption and factors. Powder characterisation. solid-liquid and liquidliquid. eye. stability testing and storage. 5. 29 . formulation. Different mixers: solid-solid. formulation of coating solution. 3. fluid energy mill etc. rubber. colloid mill.. lipstick. sugar coating. Laws of crushing and grinding. Problems of mixing and mixer selection. after-shave lotions. film forming materials. Si alloys. solubility curves. different types of tablet compression machinery and equipment employed. nucleation. tank type.V Pharmaceutics (Pharmaceutical Technology-II) Theory Code: Contacts: Credits: 4 PT 506 3L + 1T = 4 1. etc. Mo. evaluation of tablet. Physiological availability and tablet coating. supersaturation theory. granulation technology on large scale by various techniques. Al. hall mill.. material for production of hard gelatine capsules. glass. sealing and packaging. 6. fluid classifiers. laws of sedimentation. preparation. Industrial crystallisers like Swenson-Walker. Different problems of crystallisation like caking etc. aluminium. Different linings and surface coatings.29 3. Size Reduction and Size Separation : Utility of size reduction and separation. Cosmetology and Cosmetic preparation : Fundamentals of cosmetic science. shaving cream. equipment for coating./week 2 Practicals will be conducted as per the subject content in theory (at least 7 experiments) SEMESTER . hair. Manufacturing area design and layout flow diagram of tablet manufacturing. polymers. packaging and evaluation of cosmetic products for skin. Soft gelatine capsules shell and its content. Practical Contacts : Credit : Code : PT 497 3 hrs. particle size analysis. 4. specially stainless steel. hammer mill. material properties. 2. metals. different crushers and grinders like Roll crusher. Mn. coating process. Mixing : Sampling and statistics of mixing. method of capsule filling. Crystallisation: Introduction – Crystal characteristics. b) Coating of tablets : Types of coating.

drug interaction. Bio-transmission. Anti-inflammatory and Anti-gout drugs i) Narcotic analgesics and antagonists j) Drug-Addiction and Drug Abuse. Anti-anxiety agents e) Psychopharmacological agents: Anti-depressant. hypnotics. PT 508 3L = 3 4. Antipyretics. routes of drug administration. maniacs agents f) Anti-epileptics drugs g) Anti-Parkinsonian Drugs h) Analgesics. PT 509 3L Introduction to the scope of microbiology Structure of bacterial cell. 2. Pharmacology of Peripheral Nervous System : a) Neurohumoral transmission (amines and related substance) b) The choline esters and cholinesterase. PT 596 3 Formulation of various types of cosmetics for skin. Pharmacology Theory Code: Contacts: Credits: 3 1. Factors modifying drug action and related conditions. evaluation and packaging of hard gelatine capsules. 30 . evaluation and packaging of tablets Preparation . mechanism of action. 5-hydroxy tryptamide. b) General Anaesthetics. 2. General Pharmacology : Introduction to Pharmacology. Atropine and atropine like drugs. c) Neuromuscular blocking agents. 6.N. the cyclic neucleotides. Fate of the drug and its administration. Preparation.S. Drugs that block neuro-musculer or ganglionine transmission. 3. hair. eye and different type of preparations. Metabolism and Execration of drugs (ADME). 3. local anaesthetics c) Alcohols and disulfiram d) Sedatives. Absorption. Screening and testing of drugs Toxicity of drugs Pharmaceutical Microbiology 5. histamine and its antagonist Pharmacology of Central Nervous System : a) Neurohumoral transmission in the C. Adverse Drug Reactions. Distribution. Theory Code: Contacts: Credits: 3 1. Autogonists if adrenergic neurone activity. Combined effect of drugs. 2.30 Practical Code: Contacts: Credits: 2 1.

Receptor based drug design like cyproheptadine HCL. diclofenac sodium. structure activity relationship including physico-chemical properties of the following classes of drugs : Drugs acting at Synaptic and neuro-effector junction sites : i) ii) iii) iv) 3. electron microscope. structure activity relationship including physicochemical properties of the following classes of drugs : 31 . Sulmonella typhi. like Staphylococcus aureus. E. Vitamins (Vitamin B12 & Niacin). viruses. fungi. testing the sterility of pharmaceutical products as per I. CADD. etc. rickettsiae. Cholinergics and Anti-cholinesterases Adrenergic drugs Antispasmodic and anti-ulcer drugs Neuromuscular blocking agents. ibuprofen and analgin. Microbial assays of antibiotics. coli. 6. 8. cultivation. sterilization techniques and their validation of sterilizing techniques. evaluation of antiseptics and disinfectants. Immunity. requirements. Synthetic procedures of selected drugs : Mode of action.31 3. Water analysis by microbiological method Pyrogen by LAL Test PT 599 3 Experiments devised to prepare various types of culture media. 10. Diseases and disease-producing microorganisms. geometric and bioisosterism) of drug molecules and biological action. Sterility testing of all Pharmaceutical products. defensive mechanisms of body. uses. statistical loop for QSAR. microbial resistance. various methods of isolation and identification of mircobes. Streptococcus pyrogenes. disinfectants and antiseptics and their evaluation. 4. PT 503 3L + 1T = 4 2. Concept of QSAR and descriptors. 9. 7. 4. virulence factors. uses. factors influencing disinfectants. dynamics of disinfection. classical QSAR (Hansh and freewilson methods). Control of microbes by physical and chemical methods. Nutrition. Practical Code: Contacts: Credits: 2 Classification of microbes and their taxonomy. amino acids. Vibrio choleri and Yersinia pestis. fungus and yeast. different methods. microbial assay of antibiotics and vitamins. primary and secondary. b) Sterilization. actinomycetes. paracetamol.P. validation of sterilization methods & experiments. Synthetic procedures of selected drugs : Mode of action. 12. 11. various staining methods. spirochetes and viruses. Identification of Microbes : Stains and types of staining techniques. isolation of bacteria. sub-culturing of common aerobic and anaerobic bacteria. water analysis. interferon. a) Disinfection. Actinomycetes bacteria. 5. Drug-receptor interaction including transduction mechanisms. Basic Principles of Medicinal Chemistry : Physico-chemical aspects (Optical. Pharmaceutical Chemistry (Medicinal Chemistry) Theory Code: Contacts: Credits: 4 1st Half : 1.

Regulation of gene expression. Practicals Code: Contacts: Credits: 2 1. Assimilation of ammonia. 6. Diclofenac sodium. Physical & chemical mutagenesis/carcinogenesis. PT 593 3 Synthesis of selected drugs from the course content (at least 3 experiments). post translational modifications and distribution of protein of different organelles. Biosynthesis of RNA (Transcription) and Post transcriptional modifications. Brief account of genetic engineering and polymerase chain reactions. Components of protein synthesis. histidime. alteration and rearrangements of genetic material. PT 504 3 Hormones : Pitutary gland. Pharmaceutical Engineering Theory Code: Contacts: Credits: 3 PT 507 3 32 . Biosynthesis of Nucleic Acids : Brief introduction of genetic organization of the mammalian genome. 3. Urea cycle.32 a) Autocoids i) Antihistamines ii) Eicosancids iii) Analgesic-antipyretics. Ibuprofen and Analgin Pharmaceutical Chemistry (Bio-chemistry ) Theory Code: Contacts. catabolism of amino acids (phenyl alamine methionine. alanine protein glycine) Conversion of amino acids to specialised products. 2. Biosynthesis of DNA and its replication. 5. and Inhibition of protein synthesis. Special analysis of some selected drugs from the course content like cyproheptadine HCL. 2. bio-synthesis of amino acid. ergot alkaloids and prostaglandins) Biochemical approaches in drug designing wherever applicable should be discussed. Metabolism of sulphur containing amino acids. hyperbilirubinemia. 3. formation of bile pigments. anti-inflammatory (non-steroids) agents. Credits: 3 1. Porphyrin biosynthesis. Vitamines : Water and fat soluble vitamines Genetic Code and Protein Synthesis : Genetic code. paracetamol. DNA repair mechanism. metabolic disorders of urea cycle. Purine biosynthesis. 4. Establishing the pharmacopoeial standards of the drugs synthesized. Pyrimidine biosynthesis. b) Drugs affecting uterine motility : Oxytocics (including oxytocin. and Formation of deoxyribounucleotides. Purine nucleotide interconversion. Mutation. Thyroid gland and hormones secreted from pancreas Metabolism of Ammonia and Nitrogen Containing Monomers : Nitrogen balance.

principles of refrigeration. 2. pneumatic. Laws governing energy and power requirements of size Reduction.33 1. 8. 3. Evaluation of filter media. fluidized-bed. structure activity relationship including Physico-Chemical properties of the following classes of drugs : 1. Antiparkinsonism drugs. Psychometirc chart. theory of drying. Anti-platelet and antihyperlipidemics 2. Process control system: Basic instrumentation and control in pharmaceutical industries. antidepresants. bubble cap. free moisture content and bound moisture content. mode of action. molecular and azeotropic distillations. sieve phate and packed bed columns. rotary. rectification of binary mixtures. Determination of humidity – use of Dry Bulb and Wet Bulb. equipments like batch extractor. antihypertensive. problems (mathematical problems) Drying : Mechanism of drying. vacuum and level by automatic process control systems. pharmaceutical dryers like tray. uses. drying problems. SEMESTER – VI Pharmaceutical Chemistry (Medicinal Chemistry) Theory Code: Contacts: Credits: 4 PT 603 3L + 1T = 4 Synthetic procedures of selected drugs. humidity measurement. Practical Code: Contacts: Credits: 2 1. 6. 5. Diuretics. Experiments to illustrate principles of size reduction. Equipments for humidification and dehumidification. FMC. Experiments on batch distillation and to verify Reileigh’s equation. mathematical problems Distillation: Batch distillation. flow rate. determination of Reynold’s number and calculation of Frictional losses. 5. PT 597 3P Measurement of flow of fluids and their pressure. problems (Mathematical problems) Extraction: Solvent extraction (liquid-liquid) and leaching. Antipsychotic. centrifugal extrictor. Humidification and Refrigeration: Dry and wet bulb thermometry. CMC. 6. Cardiovascular drugs (anti-anginal. determination of rate of filtration and study of factors affecting filtration. Determination of rate of evaporation. 4. 2. steam. anticoagulant. 4. anti-convulsants. vacuum. mathematical problems. design method of plate co. concept of EMC. measurement of temperature. parallel current and cross-treatment method. 33 . continuous leacher etc. 3. Hypnotics and Sedatives. Local Anesthetics. humidity. Introduction to interphase mass-transfer. Molecular Diffusion and Interphase Mass Transfer: Molecular diffusion in gas and liquid systems. Determination of overall heat transfer co-efficient. 7. pressure.umns. refrigerants. pharmaceutical application and mathematical problems. freeze and infrared dryers. units of refrigeration. drying rate curves. Drugs acting on the Central Nervous System : General Anesthetics. spray. vacuum. study of the performance of different dryers. application in pharmacy. antirrhythmic. Determination of rate of drying.

warfarin sodium. Synthesis and identification of selected compounds from the course content (Benzil. lyophillization and preparation of sterile powders. preparation of solution and suspension. 2. transdermal therapeutic systems. preparation and sterilization of surgical catguts. c) Pre-filling treatment. Packaging of Pharmaceutical Products : Packaging components. closures and their selections. Alnatoids – Definition. Diphenyl hydantoin. vials. absorbents. adrenocorticoids. nonaqueous vehicle. Assay of some selected drug formulation from the course content (Propranolol HCL. androgens and anbolic agents. 4. absorbable and non-absorbable sutures. washing of containers and closures. diazepam) (any four). packaging equipment. e) Sterility testing of pharmaceuticals. b) Formulation details. equipment for large scale manufacture and evaluation of parenteral products. pyrogenicity. verapamil hydrochloride. Novel drug delivery system : Introduction to novel drug delivery systems like micro-capsule and micro-pellet parenteral and implantable therapeutic systems. Practical Code: Contacts: Credits: 2 PT 696 3 34 . filling and closing of ampoules. Benzocaine ). laminar flow bench services and maintenance. design of aseptic area. Parenteral Products : a) Pre-formulation factors. stability aspect of packaging. containers.. micro-particulate drug carrier system. determination of functional group and structure elucidation of Atropin and Ephidrine Practical Code: Contacts: Credits: 2 1. ligatures and catguts. factors influencing choice of containers. chlordiazepoxide. bandages. estrogens and progestational agents. general identification test. legal and other official requirements for containers. water for injection. infusion fluids. routes of administration.34 3. surgical gauze etc. 3. adhesive tape. packaging testing. spironolactone. 2. Benzillicacid. d) Aseptic Techniques : source of contamination and methods of prevention. 3. protective cellulosic hemostatics. PT 693 3 Workshop on stereomodel use of some selected drugs. primary wound dressing. types. method of preparation and evaluation. surgical cotton. isotonicity and methods of its adjustment. 4. Steroids and related drugs : Steroidal nomenclature and stereochemistry. specifications and methods of evaluation. official dressing. Surgical Products : Definition. micro-encapsulation – types. Pharmaceutics (Pharmaceutical Technology) Theory Code: Contacts: Credits: 3 PT 606 3 1.

tmax and area under the curve (AUC).35 1. Design of single dose bio-equivalence study and relevant statistics. i) Non-linear pharmacokinetics with special reference to one compartment model after I. h) Extraction ratio. 2. f) Curve fitting(method of Residuals). plasma protein binding. Preparation of a sustained release oral dosage form and its evaluation Evaluation of materials used in pharmaceutical packaging.2 Factors influencing absorption-Physicochemical. Clinical Pharmacokinetics : a) b) c) d) Definition and scope Dosage adjustment in patients with and without renal and hepatic failure. 2. Cmax. b) Design of single dose bio-equivalence study and relevant statistics. facilitated diffusion and pinocytosis) 2. c) Review of regulatory requirements for conduction of bio-equivalent studies. g) Clearance concept. Determination of pharmacokinetic parameters from plasma and urine data after drug administration by intravascular and oral route. regression procedures.V. hepatic clearance. active transport. 4) Introdution to Biopharmaceutics and Pharmacokinetics and their role in formulation development and clinical setting. Pharmacokinetic drug interactions and their significance in combination therapy. 2. Pharmaceutics (Biopharmaceutics and Pharmacokinetics) Theory Code: Contacts: Credits: 4 PT 611 3L + 1T = 4 1. e) Compartment kinetics-One compartment and two compartment models. drug administration. clearance ratio. Michaeles Menten Equation.1 Passage of drugs across biological barrier (passive diffusion. Bioavailability and bioequivalence : a) Measures of bioavailability. Practical Code: Contacts: Credits: 2 PT 697 3P 35 . Biopharmaceutics : 2. Paraffin gauge dressings. Mechanism of renal clearance. determination of renal clearance. 5. 3. Pharmacokinetics : a) Significance of plasma drug concentration measurement b) Compartment model-Definition and Scope c) Pharmacokinetics of drug absorption-Zero order and first order absorption rate constant using Wagner – Nelson and Loo-Reigelman method. detection of non-linearity (Saturation mechanism). physiological and pharmaceutical. 3. Extrahepatic circulation. biliary excretion. d) Volume of distribution and distribution coefficient.3 Drug distribution in the body.

and inflammatory activity and muscle relaxant activity of drugs using simple experiments. bioassay of acetylcholine. Drugs acting on urinary system : a) Fluid and electrolyte balance b) Diuretics Autocoids : a) Histamine. stereotype. In vitro evaluation of different dosage forms for drug release. 3. 36 . 4. adrenaline. c) Fibrinolytic and anti-platelet drugs Bioassay: Definition. Vitamin K and hemostatic agents. Analysis of biological specifications for drug content and estimation of the pharmacokimetic parameters. 5. Effects of autonomic drugs on rabbit’s eye : 3. different hormones. anticonvulsant activity. 3. digitalis. Absorption studies – in vitro Statistical treatment of pharmaceutical data. hydroxytryptamine. PT 608 3 Pharmacology of Cardiovascular System : a) Digitalis and cardiac glycosides b) Antihypertensive drugs c) Anti-anginal and Vasodilator drugs d) Anti-arrhythmic drugs e) Anti-hyperlipedemic drugs f) Drugs used in the therapy of shock Drugs Acting on the Hemopoetic System : a) Hematinics b) Anticoagulants. noradrenaline. 6. merits and demerits threshold dose bracketing. analgesia. 2. Experiments on Central Nervous system : Recording of spontaneous motor activity. sedative agents. local anesthetics. thromboxanes and leukotrienes Drugs Acting on the Respiratory System : a) Anti-asthmatic drugs including bronchodilators b) Anti-tussives and expectorants 2. etc.36 1. Pharmacology Theory Code: Contacts: Credits: 3 1. Practical Code: Contacts: Credits: 2 1. PT 698 3 Experiments on intact preparations : Study of different routes of administration of drugs in mice/rats. 5-HT and their antagonists b) Prostaglandins. 2. oxytocin. four point and other assay. 4.

5. Study of enzymes such as hyaluronidnse. Genetic Recombination : Microbialgenetics & variation. Vaccines – preparation. 2. HB etc Antibiotics : Historical development of antibiotics. b) To study the effects of physostigmine and d-tubocurarin on the CRC of acetylcholine using rectus abdominis muscle preparation of frog. its design. types of reactions mediated by microorganisms. factors affecting enzyme kinetics. Isolation of mutants. 6. Pharmaceutical Biotechnology & Industrial Microbiology Theory Code: Contacts: Credits: 3 PT 609 3 1.37 4. Immune system. Study of drugs produced by biotechnology such as Activase. 6. Screening of soil for organisms producing antibiotics. Enzyme immobilization : Techniques of immobilization of enzymes. biotransformation process and its improvements with special reference to steroids. amylases and proteases etc. antigen-antibody reactions and their applications. Immobiliztation of bacteria and plant cells. Humatrope. Fermentative Production of alcohol Elective-I 4. penicillinase. streptomycins tetracyclines and vitamin B12. protoplast fusion and gene cloning and their applications. selection of organisms. Transformation. Isolation of fermentation products with special reference to penecillins. 3. control of different parameters. c) To record the CRC of 5-HT on rat uterus preparation. f) To record the CRC of oxytocin using rat uterus preparation Abnormal toxicity test (Phenol) 5. Effects of various agonists and antagonists and their characterization using isolated preparations like frog’s rectus abdominis muscle and isolated ileum preparations of rat guinea pig and rabbit. Immunology and Immunological Preparations : Principles. immunological tolerance. Design of fermentation process. antigens and Haptens. Development of hybridoma for monoclonal antibodies. Microbial Transformation : Introduction. design of biotransformation processes. transduction. fermenter. factors influencing rate of mutation. Antimicrobial spectrum and methods used for their standardization. standardization and storage. streptokinase and streptodornase. Humulin. active and passive immunization. Hypersensitivity. d) To record the CRC of histamine on guineapig ileum preparation e) To record the CRC of noraderenaline on rat anococcygeus muscle preparation. cellular humoral immunity. conjugation. Theory Code: : Contacts: Credits: 3 3L 37 . Experiments on Isolated Preparations : ( at least three) a) To record the concentration response curve (CRC) of acetylcholine using rectus abdominis muscle preparation of frog.

Preformulation studies : a) Introduction.38 Students may opt any one of the following subjects : 1. microscopy. P-C dissolution. and their influence on formulation and stability of products. oxidation. PT610B: Advanced Pharmaceutical Biotechnology SEMESTER . development and process validation methods for pharmaceutical operations involved in the production of pharmaceutical products with special reference to tablets. hygroscopicity. Synthetic procedures uses of the selected drugs and mode of action of the following classes of drugs :. Design. suspensions. Pka. 2. Design. production and evaluation of oral controlled released formulations. 38 . Principle. Performance evaluation methods : In vitro dissolution studies for solid dosage forms method interpretation of dissolution data. density. 4. 6. qualification of preformulators. Stabilization and stability testing protocol for various pharmaceutical products. racemization. PT 796 3 Dissolution testing and data evaluation for oral solid dosage forms. development and evaluation of controlled release formulations. reduction. Practical Code: Contacts: Credits: 2 1. PT610A: Computer Application in Pharmaceutical Technology and in Clinical Pharmacy 2. powder flow. 3.VI Pharmaceutics (Pharmaceutical Technology) Theory Code: Contacts: Credits: 3 PT706 3 1. 5. solubility. 2. Quality audit. Note: At least seven experiments to be performed Pharmaceutical Chemistry (Medicinal Chemistry-III) Theory Code: Contacts: Credits: 3 PT 703 3 Structure. c) Study of pro-drugs in solving problems related to stability bio-availability and elegancy of formulations. thermal analysis. x-ray polymorphism. b) Study of chemical properties of drugs like hydrolysis.. GMP and quality assurance. polymerization etc.

2. types of cultures. Anthelmintic Fluoroquinolones. diosgenin and sarasapogenin. Carotenoids : α-carotenoids. Macrolides. Chloramphenicol. Isonicotinic acid etc. macrolides. preservation of important medicinal plants and herbs Screening of flavonoids and polyphenols in plant extracts. ethambutol. aminoglycosides. nutritional requirements. sulphacetamide.. Antileprotic and Antitubercular drugs). Alkaloids : Chemistry. Metformin HCL. collection. 3. quinine. digoxin. Antimaoebic. 2. novel medicinal agents from marine sources. Historical development of plant tissue culture. Basic metabolic pathways and biogenetics of secondary metabolites of pharmaceutical importance. 7. morphine. PABA. Practical Code: Contacts: Credits: 2 PT 793 3P Anti-biotics & Chemotherapeutic agents : β-lactam. 10. Antifungal. Marine pharmacognosy. sesquiterpenes. growth and their maintenance. 8. papaverine. biogenesis and pharmacological activity of atropine and related compounds. ergot and vinca alkaloids. 6. Herbal cosmetics 5. Pharmacology Theory Code: Contacts: Credits: 3 PT 708 3 39 . 9.39 1. reserpine. 2. antimalarial. Applications of plant tissue culture in pharmacognosy. Trimethoprim) Pharmacognosy Theory Code: Contacts: Credits: 3 1. general method for isolation of alkaloids. Cultivation. Antineoplastic agents Thyroid and anti-thyroid drugs Insulin and oral hypoglycaemic agents 1. identification. hecogenin. sennosides.) Pharmacopoeial assay of any four selected drugs (any three) formulations (Chlorpropamide. β-carotinoids. Xanthophylls of medicinal important. Antiviral. Synthesis of any three selected drugs (e. ephedrine. Glycosides : Chemistry and bio-synthesis of digitoxin. 3.g. Albendazole. chloramphenicol. PT 702 3 Biogenesis and pharmacological activity of medicinally important monoterpenes. 4. Rifampicin. 4. diterpenes and triterpenoids. Vitamin A.

urinary tract infections and sexually transmitted diseases. Ledger posting and book entries. 3. Directing and Controlling). Bank reconciliation statement. Marketing. Profits and 40 . c) Emetics and anti-emetics Elective -II 2. Motivation. rectification of errors. calcitonin. Innovation. Time/space. Cephalosporins. Communication. Quinolones and Miscellaneous Antibiotics. Accountancy : Principles of Accountancy. 2. g) Drugs acting on the uterus. Staffing. Code: Contacts: Credits: 3 3 Students may opt any one of the following subjects : 1. viral diseases. a) General Principles of Chemotherapy b) Sulfonamides and cotrimoxazole c) Antibiotics-Penicillins. progesterone and oral contraceptives. Materials. leprosy. Pharmacology of Endocrine System : a) Hypothalamic and pituitary hormones b) Thyroid hormones and anti-thyroid drugs. Financial. Delegation of Authority/Responsibility. Entrepreneurship development. Record Keeping). e) Chemotherapy of malignancy and Immunosuppressive Agents Drugs Acting on the Gastrointestinal Tract : a) Antacids. Project Code: PT 783 Contacts: 8 Credits: 6 SEMESTER – VIII Pharmaceutical Industrial Management Theroy Code: Contacts: Credits: 3 1. fungal diseases. d) Chemotherapy of tuberculosis. oral hypoglycaemic agents & glucagon d) ACTH and corticosteroids e) Androgens and anabolic steroids f) Estrogens. Anti Secretory and Anti-ulcer drugs b) Laxatives and anti-diarrhoeal drugs. 3. Margin/Morale). c) Insulin. Principles of Management (Co-ordination. PT 812 3 PT709A: Packaging Technology PT709B: Advanced Pharmacognosy PT709C: Pharmaceutical Marketing Management 2. Organizing. Decision-making. leadership. Chemotherapy . Operative Management (Personnel. Etythromycin. Concept of Management : Administrative Management (Planning. Chloramphenicol. columns of a cash book. Creativity.40 1. Production. Identification of Key points to give maximum thrust for development and perfection. preparation of trial balance.

Production Management : A brief exposure of the different aspects or Production. departmental store. demand curves. feedback. 4. b) Market Segmentation & Market Targeting. promissory notes and hundies. scope. f) Patents Act (latest) Note: The teaching of all the above Acts should cover the latest amendments. Recruitment. loss account. demand schedule. procedure of exporting and importing goods. compensation to the pharmacist. ManagementVisible and Invisible inputs. PT 813 3 Introduction Pharmaceutical legislation – A brief review. 7. 41 . training. selling. ISO 9000 and TQM 10. multiple shop and mail order business. An elaborate (practical oriented) study of the following a) Pharmaceutical Ethics b) Pharmacy Act 1948 c) Drugs and Cosmetics Act 1940 and Rules 1945 An elaborate (practical oriented) study of the following d) Medicinal & Toilet Preparations(Excise Duties) Act 1955 e) Narcotic Drugs & Psychotropic Substances Act 1955 & Rules f) Drugs Price Control Order. merchandising. Process-Flow. Market share & Future demand. transportation. treatment of cheques. Market Research : a) Measuring & Forecasting. buying. demand measurement. wholesale. 8. an evaluation of material management. c) Prevention of Cruelty to Animals Act 1960. A brief study of the following with special reference to the main provisions. 11. Pharmaceutical Jurisprudence & Ethics Theory Code: Contacts: Credits: 3 1. information. Materials Management : A brief exposure or basic principles of materials management-major areas. Geo-demographic analysis. Personal Management Concept of GLP. d) States Shops & Establishments Act & Rules. 5. Methodology of Activities. ethics of sales. Market Demands. Economics : Principles of economics with special reference to the laws of demand and supply. Maintenance Management. e) Factories Act 1948. 3. 2. balance sheet. general principles of insurance and inland and foreign trade. documentary bills. purchase. evaluation. finance. literature.41 3. keeping and pricing of stocks. labour welfare. purchase. detailing. bills of exchange. 9. Performance Evaluation Technique. channels of distribution. inventory control. Estimating industry sales. advertising. Process Know-how. 3. a) Drugs and Magic Remedies(Object Advertisements Act 1954) b) Medical Termination of Pregnancy Act 1970 & Rules 1975. Estimating current demand. retail. Major conception. Pharmaceutical Marketing : Functions. storage. stores. Salesmanship : Principles of sales promotion.

production control. elements of interpretation of spectra and applications of the following analytical techniques would be discussed : 1. demand and costing. Master formula Card. Schizophrenia. a) Drug use during Pregnancy b) The Basics of Drug Interactions. Hospital Formulary : Contents. 2. Concept of Essential Drugs and Rational use of drug.42 Hospital & Clinical Pharmacy Theory Code: Contacts: Credits: 3 PT 818 3 Hospital pharmacy : 1. Ultraviolet and visible spectrophotometry Fluorimetry Infrared spectrophotometry(FT-IR – an introduction) Flame Photometry Nuclear Magnetic Resonance Spectroscopy Mass-spectrometry Atomic Absorption spectroscopy 42 . preparation and revision of hospital formulary. Depression. Introduction to Clinical Pharmacy. Basic Concepts of Pharmacotherapy. b) CNS Disorders : Epilepsy. 4. Organisation and Structure : Organisation of hospital pharmacy. 3. 2. b) Dispensing of drugs to in-patients. Manufacture of Sterile and Nonsterile Products : Policy making of manufacturable items. drug-food interaction. basic instrumentation. Clinical Pharmacy 1. Drug distribution Systems in Hospitals : a) Out-patient dispensing. Basic concepts of Clinical trials – Phase-I. 5. Responsibilities of a hospital pharmacist. Charging policy. Parkinsonism. Angina. labelling. Important Disorders of Organ Systems and their Management : a) Cardiovascular Disorders-Hypertension. personnel requirements. methods adopted. 4. Manufacturing records. pharmacokinetic and pharmacodynamic drug interaction. 3. 7. 6. types of drug-drug interaction. 2. Cardiac arrhythmia. Congestive Heart Failure. Phase-III & IV Basic concept of Clinical trial monitoring Pharmaceutical Analysis Theory Code: Contacts: Credits: 3 PT 801 3 3. Acute Myocardial Infraction. manufacturing practice. The theoretical aspects. Types of drug distribution systems. Pharmacy and therapeutic committee. 5. 4. 6. Phase-II.

Use of database management system (DBMS) in clinical drug interaction and drug information services.43 8. Database architecture.I Computer application in Pharmaceutical Technology Paper Code :PT 610A 3 hr / week Relational Database and SQL Introduction to data base. using instrumental techniques Estimation of Na+. Database versus early file keeping system. nonlinear regression. Statistical analysis using standard package Linear Regression and Correlation: Introduction. Analysis of residuals. users and administrators. 2. DBMS. Ca++ ions using flame photometry. Practical Computer application in Pharmaceutical Technology Paper Code :PT 691A. K+. tables and fields. need for DBMS.and BCNF Structured Query Language (SQL) 1. Contact : 3 Credit : 2 Exercise based on topics like : 1. Relational databses design : Functional Dependencies. ELECTIVE SUBJECTS SEMESTER-VI Elective . confidence label. Practical Code: Contacts: Credits: 2 1. 2NF. Creating and modifying table with Oracle. Database Languages. 1NF. Integrity-: domain constraints and referential integrity Introduction to Relational Database. 2) 3) Computer aided drug design:. PT 891 3 Radio immunoassay Quantitative estimation as per pharmacopoeial method of at least seven formulations containing single drug or more than one drug. Studies of this parameter through computer package. querying with SQL Quantitative structure activity relationship Data base system and use of this system using FOXPRO or Microsoft Access in clinical drug interaction and drug information services 43 . 2. Fitting lines. types of databases. decompostion. 3.A preliminary approach to QSAR and combinatorial chemistry. 3NF.

44 Advanced Bio-technology [ PT 610 B ] 1. 44 . chemical) 4. biological. Introduction & historical background a) b) Scientific & Technological foundations Micro & nano-technology for medicine 2. 6. 7. Bio-technology & Medicines a) c) e) a) Vitamins b) Amino acid d) Antibiotics f) Gene farming i) Animals i) Plants Steroids Proteins Natural compounds 3. Recombinant DNA Technology a) Concept b) Cutting and rejoining of DNA c) DNA segregating d) PCR in gene amplification e) Isolation and amplification of gene Bio-informatics a) Molecular pharmaceutical biotechnology Moral and ethical questions (safety – medical. PRACTICAL [ PT 691B ] 1. 3. Microtechnique : Preparation of animal tissue sections for histological / histopathological / immunocytochemical studies Estimation of hormone concentration from blood serum by immunoassays like ELISA Extraction of (a) total RNA ] (b) DNA ] from tissue extracts (c) Protein ] Spectrophotometric assay of enzymes Estimation of (a) Serum Glutamate Oxaloacetate Transaminase (SGOT) Test (b) Serum Glutamate Pyruvate Transaminase (SGPT) Test (c) Protein with standard curve by Ninhydrine method 2. 5. Protein separation by gel eletrophoresis a) Assembling of Electrophoresis apparatus b) Gel casting c) Loading of proteins in the gel and separation according to molecular weight d) Staining of protein bands in the gel.

a. Closures. Drug-plastic considerations. selection of proper materials. 2. Shrink bonding.containers and Closures Introduction. Closures and containers for different liquid and semisolid formulations. Different Markets. sealed containers. c. Unit dosage packaging. Packaging. Modern packaging metal. methods of preparation. Product offering. Bubble pack. Nature of package evaluation Packaging of solid oral dosage form : scope. Segmentation of Market. drug powder inhalers.45 SEMESTER-VII Packaging Technology (Elective –II) Code: Contact : Credit : 1. iii) Concept of Marketing – Definition of marketing. Influence of packaging components on dosage form stability. 4. regulatory requirement. wants & Demands. composition. Scope of Marketing. Needs.containers and Closures Introduction. metered dose inhalers.pressurized containers. Metal packaging materials . Packaging materials science Glass packaging materials . paper of plastic pouches. sealed tubes. Relationship net work. Types of metal containers. (PT 709A) 3 3 Packaging of pharmaceutical dosage form Introduction. tape seals. value & satisfaction. d. containers. a. Tinplate and associated materials aluminum. b. 1. Plastic packaging materials . foil. aerosol containers. breakable caps. Blister package. Target Market. c. drug plastic considerations. types. bottle seals. b. Quality control and storage of packaging materials. e. Packaging of parenteral and ophthalmic: scope. Supply chain competition. regulatory requirements. Film Wrapper. Definition and function. 3. non. Designing packages for disposability (Wastage control) Pharmaceutical Marketing Management (Elective-II) Code: Contact : Credit : [ 709 C ] 3 hrs. Marketing Place. Marketing Environment. Other concept’s name under marketing activities. f. Tamper – Resistant packaging Introduction. Packaging of semisolids and topicals: scope. Marketing Mix ( 4 P Components). spray pumps. transdermal devices. strip package. Selection of proper materials. Core Marketing Concept. 45 . Distinction between marketing & Selling. / week 3 Understanding of Pharmaceutical Marketing Management Defining Marketing ii) Marketing Task – Demand States & Marketing task. pressurized containers. Packaging of aerosols: scope. Marketing Space. classification of materials. manufacture of glass. stability and shelf life containers and Closures.containers and Closures Glass as a packaging material.

Marketing Research. Selecting. Market Testing. Choosing the Advertising Message. b. Forecasting & Demand Measurement. Dealing With the Competition . Designing Competitive Strategies. Types of Wholesaling. Indigenous systems of medicines with emphasis on Ayurveda. Sales Promotion & Public Relations . Adulteration & deterioration Factors affecting Herbs quality TLC / HPTLC Sampling procedures Morphological examination Microscopical evaluation Chemical evaluation 46 . Stragic Formulation. Motivating & Evaluating Channels Members. Behavioural Research. Channel Dynamics. Conflicts.Recruitment & Selecting Representative.46 1) 2) 3) 4) Marketing Opportunities Market Oriented Strategic Planning – SWOT Analysis. Wholesaling & Market Logistics . c.3 period / week Credit : 3 2) 3) 4) 1. Product Development. 2. Product Planning. Product Strategy Positioning & Differentiating the Market Offering (Product) . g. Product Line analysis. Decisions. Norms for Customer Calls. Brand Decision.Product Life Cycle New Market Offering – Which markets to Enter. Training sales Representative.Identifying Competitors. Co. Public Relations. How to Enter the Market. Strategies. d. Sales Promotion & Purpose.II Advanced Pharmacognosy Paper code : 709B Contact . Analysing Consumer Markets & Buyer Behaviour – Influencing Buyer Behaviour. Motivation of Physician towards Brand. Gathering Information & Measuring Demand – MIS. Managing Sales Force. Analysing Competitors. Elective . 1) 2) 3) Developing Market Strategies & Marketing Mix. Managing Advertising.operation & Competitions. Managing & Delivering Marketing Programs 1) Value Net.Positioning to Promote.Advertising Objective. Channel Levels. 4) Setting the Product Strategy – Product & Product Mix. Product Life Cycle marketing Strategies.. Buying Decision Process. e. Some important techniques associated with quality control of Herbal Drugs :a. Managing Retailing. Market Research. Strength & Weakness. Evaluating Sales representative.Types of Retailing. Supervising. Motivating Sales representative. Packaging & Labeling. f.Work & Marketing Channels – Channel Functions. Training. Channel Management. Measuring Effectiveness of Advertisement.

5. Extracrion of herbal drugs a. There will be no separate class test in practicals. the university degree certificate may continue to remain the same with no mention of elective subjects. norms. Complete coverage of prescribed syllabus in university question papers is desired.U. viva. Quality assurance & stability testing of herbal drugs. 2. b. Pharm is a professional degree course with diverse employment potential. 8. However. Internal assessment of practicals (40%) will be based on day to day attendance. Pass mark in both theory and practical papers is as per WBUT norms. Presence of External Examiner in Practical examinations is mandatory.47 3. In view of the fact that B. Practical examination is essential as per PCI norms : iii) iv) Sessional Practical examination : : 40 60 4. of 1st and 2nd Semester before appearing in the 5th Semester Examination and the same of 3rd and 4th Semester before appearing in the 7th Semester Examination. c. The choice in question papers shall be restricted to 25% only. 11. 10. 6. Student has to clear back paper(s). A student will get a maximum of 8 yrs. Pass mark in aggregate will be as per W. 5. 12. time from the date of admission to complete the degree course. Class / Division awarded to the student will be decided as per WBUT norms. laboratory record etc. Each Semester will consist of a minimum of 15 weeks instructions : Internal assessment of Theoreticals (30%) will be based on two class tests of 10 marks in each of the theory subject during each semester and 10 marks for class attendance of student in each subject. solvent mixture & solution of extraction Procedure of extraction e) Treatment of dry residue after extraction INSTRUCTIONS 1. the mark-list should indicate the elective(s) opted by the candidate. Basic principle Preextraction operation for crude drugs Effect of solvent. 4. 7. 3.T. A minimum of 75% attendance in theory and practical classes is compulsory. if any. Pharmacological Screening of herbal drugs. 9. 47 . d.B.

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