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FACULTY OF PHARMACY
(Deemed University) Hamdard Nagar, New Delhi - 110062
ADMISSION & EXAMINATION RULES FOR BACHELOR IN PHARMACY
FACULTY OF PHARMACY ADMISSION & EXAMINATION RULES BACHELOR IN PHARMACY
(Approved by the Standing Committee of the Academic Council in July 2004, to be effective from the Academic Session 2004-05 and applicable to all B. Pharm. students) 1. Program: Bachelor in Pharmacy (B. Pharm) It shall be a fulltime regular course. Duration an academic year, a candidate shall be enrolled only for one program of study and shall not appear in any other examination of this or any other University. 2. Duration: Four years 3. Medium of Instruction and Examination: English 4. Eligibility for admission: A candidate seeking admission to this course must have: a) Passed 10+2 examination from Central Board of Secondary Education, or any other examination recognized by Jamia Hamdard as equivalent thereto, with at least 50% marks in the aggregate of Physics, Chemistry and Biology subjects, and must have passed in each of these subjects. b) Qualified the admission test/interview conducted by Jamia Hamdard. c) Completed the age of 17 years on or before the first day of October of the year of admission. Some seats are provided for those candidates who opt for an additional course in Unani Pharmacy. All such candidates will have to appear in all the subjects of Modern Pharmacy in addition to the additional papers in Unani Pharmacy (Urdu medium). On the successful completion of the course, these candidates will be entitled to award of degree in Modern Pharmacy and a separate certificate for Unani course. Proficiency in Urdu, comparable to Matric standard is essential for such candidates. 5. Course structure: The numbers of hours of teaching in theory as well as practical in the various subjects of this course are listed below. The course contents are given in the syllabus.
Course Code BPH 01 BPH 02 BPH 03 BPH 04 BPH 05 BPH 06 BPH 07 BU 01
Min. Teaching hrs. Total Theory Practical 50 50 50 50 50 50 75 375 15 100 100 100 100 100 75 75 650 150 150 150 150 150 125 150 1025 15
Ist year 1. Pharmaceutics-I (Introduction to Pharmacy) 2. Pharmaceutics-II (Unit Operation) 3. Pharmaceutics-III (Dispensing Pharmacy) 4. Pharmaceutical Chemistry-I (Organic Chemistry) 5. Pharmaceutical – II (Inorganic Medicinal & Pharmaceutical Chemistry) 6. Pharmacognosy – I
7. Human Anatomy and Physiology
Unani Pharmacy IInd year 8. Pharmaceutical Maths & Biostatistics 9. Pharmaceutics-IV (Pharmaceutical Microbiology) 10. Pharmaceutics-V (Physical Pharmacy) 11. Pharmaceutical Chemistry-III Pharmaceutical Analysis-I (Inorganic Chemistry) 12. Pharmaceutical Chemistry-IV (Organic and Medicinal Chemistry including Heterocyclics) 13. Pharmacognosy-II
BPH 08 BPH 09 BPH 10 BPH 11 BPH 12 BPH 13
50 50 75 50 50 50 25 50 25 425 15
100 75 100 100 100 100 25 575 10
50 150 150 150 150 150 25 150 50 1000 25
14. Pathophysiology, Toxicology & Health Education BPH 14 15. Pharmacology-I BPH 15 16. Computer Application BPH 16
Unani Pharmacy BU 02
17. 18. 19. 20.
21. 22. 23. 24. 25.
Pharmaceutics-VI (Hospital & Clinical Pharmacy) Pharmaceutics – VII (Forensic Pharmacy & Ethics) Pharmaceutics-VIII (Pharmaceutical Formulations & Cosmetology) Pharmaceutical Chemistry-V (Pharmaceutical Analysis-II) (Physical Chemistry & Principles of Instrumental Analysis) Pharmaceutical Chemistry-VI (Medicinal Chemistry-I) Pharmaceutical Chemistry-VII (Chemistry of Natural Products) Pharmacognosy-III (Pharmacognosy and Phytochemistry) Pharmacology-II Biochemistry
IIIrd year BPH 17 BPH 18 BPH 19 BPH 20
50 50 50 50
50 50 125 150
BPH 21 BPH 22 BPH 23 BPH 24 BPH 25
50 50 50 50 50 450 15
100 100 75 100 100 650 (2 wks.) 10
150 150 125 150 150 1100 25
Tour Report-Pharmacognosy Unani Pharmacy BU 03 IVth year BPH 26 BPH 27 BPH 28 BPH 29 BPH 30 BPH 31 BPH 32 BPH 33
26. 27. 28. 29. 30. 31. 32. 33.
Pharmaceutical Biotechnology Pharmaceutics-IX (Pharmaceutical Management) Pharmaceutics-X (Biopharmaceutics & Pharmacokinetics) Pharmaceutics-XI (Pharmaceutical Technology) Pharmaceutical Chemistry-VIII (Pharmaceutical Analysis-III) Pharmaceutical Chemistry-IX (Medicinal Chemistry-II) Pharmacognosy-IV
25 50 50 50 50 50 50 50 375 12
100 100 100 100 100 100 600 (2 wks.) 8
25 50 150 150 150 150 150 150 975 20
Tour report-Pharmaceutics Unani Pharmacy 6. Scheme of Examination: BU 04
The distribution of marks for sessional in theory and practical work in different papers during the four years of study is detailed below. The duration of annual examination in theory as well as practical papers will be 3 hours. Unless specified otherwise.
80 20 100 100 Toxicology & Health Education 15. Pharmacology-I 80 20 100 *80 20 100 200 16.3 hrs. For others -3 hrs. Pharmaceutical chemistry-I 80 20 100 #80 20 100 200 (Organic Chemistry) 5. Pharmaceutics-V 80 20 100 *80 20 100 200` (Physical Pharmacy) 11. – 4 hrs. Pharmaceutics-I 80 20 100 80 20 100 200 (Introduction to Pharmacy) 2. Pharmaceutics-II 80 20 100 80 20 100 200 (Unit Operation) 3. Pharmaceutics-III 80 20 100 80 20 100 200 (Dispensing Pharmacy) 4. Pharmacognosy-I 80 20 100 80 20 100 200 (Pharmaceutical Biology) 7.No. IInd year 8. . Pharmaceutical Maths & 80 20 100 100 Biostatistics 9. Pharmaceutical Chemistry80 20 100 #80 20 100 200 III (Inorganic Chemistry) 12. For others . Pharmacognosy-II 80 20 100 80 20 100 200 (General Pharmacognosy) 14. Pharmaceutical Chemistry80 20 100 #80 20 100 200 I (Inorganic Medicinal & Pharmaceutical Chemistry) 6.S. Pathophysiology. Computer Applications 80 20 100 80 20 100 200 Total 900 700 1600 Unani Pharmacy 80 20 100 80 20 100 200 * Duration of practical exam. . Pharmaceutics-IV 80 20 100 *80 20 100 200 (Pharmaceutical Microbiology) 10. # Duration of practical exam. Human Anatomy & 80 20 100 80 20 100 200 Physiology Total 700 700 1400 Unani Pharmacy 80 20 100 100 # Duration of practical examination -4 hrs.6 hrs. Year/Paper Marks Theory Marks Practical Grand Annual Sessional Total Annual Sessional Total Total Ist year 1. Pharmaceutical Chemistry80 20 100 #80 20 100 200 IV (Organic & Medicinal Chemistry) 13.
Pharmaceutical Chemistry-VIII 80 20 (Pharm. Pharmaceutical Chemistry-VII 80 20 (Natural Products Chemistry) 23. Internal Assessment: a) For the purpose of awarding sessional marks. etc. 100 100 100 *80 20 100 100 100 200 100 100 100 100 100 100 900 100 100 100 100 100 100 100 100 100 800 100 *80 *80 *80 *80 *80 80 80 *80 *80 *80 *80 *80 *80 80 20 20 20 20 20 20 20 20 20 20 20 20 20 20 100 100 100 100 100 100 25 725 100 100 100 100 100 100 100 25 625 100 200 200 200 200 200 200 25 1625 200 100 100 200 200 200 200 200 200 25 1425 200 7. Pharmacology – III 80 20 Tour Report Pharmaceutics Total Unani Pharmacy 80 20 * Duration of practical examination – 6 hrs. – V 80 20 (Physical Chemistry & Principles of Instrumental Analysis) 21.. Pharmacognosy-III 80 20 (Pharmacognosy and Phytochemistry) 24. Pharmaceutical Chemistry – IX 80 20 (Medicinal Chemistry) 32. Pharmaceutics-VII 80 20 (Forensic Pharmacy & Ethic s) 19. Pharmaceutics-XI 80 20 (Pharmaceutical Technology) 30. Biotechnology 80 20 27. in each course. Pharmaceutics-VII 80 20 (Pharmaceutical Formulation & Cosmetology) 20. Pharmaceutical Chem.IIIrd year 17. Biochemistry 80 20 Tour Report – Pharmacognosy Total Unani Pharmacy 80 20 *Duration of Practical Exams . The respective teachers will give these. Pharmaceutical Chemistry-VI 80 20 (Medicinal Chemistry I) 22. Pharmacognosy-IV 80 20 (Industrial Pharmacognosy) 33. Pharmaceutics-IX 80 20 (Pharmaceutical Management) 28. Pharmaceutics-VI 80 20 (Pharmacy Practice) 18. . the performance of students shall be evaluated continuously on the basis of written tests/seminars/viva voce. Pharmaceutics-X 80 20 (Biopharmaceutics & Pharmacokinetics) 29. Analysis-III) 31. For others – 3 hrs. Pharmacology-II 80 20 25. IVth year 26.6 hrs.
every scheduled practical class will be counted as one attendance unit. b) In order to maintain the attendance record of a particular course a roll call will be taken by the teacher in every scheduled lecture and practical class. g) The final sessional marks shall be submitted by the teachers to the Head of the Department who shall forward the same to the registrar. is sent to the Dean of Faculty within two weeks of the function/activity. f) The students shall maintained tour reports for assessment by the teachers conducting the tour. provided the attendance record. Attendance on account of participation in the prescribed function of NCC. if they wish so. to account for late joining or other such contingencies. Faculty of pharmacy. irrespective of the number or contact hours. NSS. etc. educational tours/field work shall be credited to aggregate. The sessional test answer books shall be retained in the Department till the end of the academic term. e) A regular record of the marks for sessional tests conducted in an academic year shall be maintained by the teacher concerned/Head of Department for each student. For the purpose of attendance. . There will be no provision for special or additional internal assessment tests. Attendance: a) All students must attend every lecture and practical class. c) The teacher in charge will consolidate the attendance record for the lectures and practicals for each term. Inter university sports. c) The marks obtained shall be notified in time by the respective teachers and answer books shown to the students. The respective teachers will hold practical sessional tests in regular classes. d) There shall be at least three tests for each course and the average of best two tests shall be taken to award the sessional marks. within ten days of the last sessional test held. These will be conducted as per a schedule notified by the Dean. However. duly countersigned by the Officer in-charge. Three tests (theory and practical) will be properly spaced in the three terms of the academic session.b) Each theory test will be of two hours duration. the attendance requirement for appearing in the examinations shall be a minimum of 75% of the classes actually held. 8. These shall also be displayed on the Notice Board of the Department/Faculty.
The Supplementary examinations may normally be held after 30 days from the declaration of results of the Annual examination. a student admitted to any course must pass the first year examination within two academic years. and no individual notice shall be sent to students. apply for readmission within 15 days from the date of issue of the Notice of striking off the name. 10. Condonation of attendance on account of any other extenuating circumstances may also be considered. the teacher in charge shall report it to the Head of Department/Dean for striking off the name of such a student from rolls. The readmission shall be effected on payment of prescribed readmission fees. A copy of the same shall be sent to the Head of Department/Office of Dean of Faculty for record. Identity card fee and Security deposits. and must complete the full course of study within prescribed span period of seven years. Further. g) A student detained on account of attendance will be readmitted to the same class in the next academic year on payments of current fees except Enrollment fee. Notice displayed on Notice Board shall be deemed to be proper notification. . The request may be considered by the Dean for readmission. e) If a student is found to be continuously absent from the classes without information for a period of 30 days. Such a student may. and must have completed the prescribed attendance requirements. Such a student shall not be readmitted after the prescribed period. f) A student with less than 75% attendance of the lectures and practicals separately in each subject/course in an academic year shall be detained from appearing in the Annual University examination. The Dean of Faculty concerned may consider application for the condonation of attendance upto 5% on account of sickness. 9. provided the application for condonation of attendance. Eligibility for admission to examination: A student seeking admission to the examination to be held at the end of each academic year must have pursued a regular course of study for one academic year. duly certified by a Registered Medical Practitioner/Public Hospital had been submitted within 5 days from the recovery from illness.d) The statements of attendance of students shall be displayed on Department Notice Board at the close of each term as given in the University Calendar. Annual and Supplementary examinations: a) The annual and Supplementary examinations shall be held as per schedule given in the Academic Calendar of Jamia Hamdard. provided the request is duly supported by documentary evidence. however.
h) Ten days vacation shall be given as preparatory holidays before the commencement of Annual Examinations. e) The duration of annual examination in theory as well as practical papers will be 3 hours. i) The candidates will retain the Internal Assessment of the previous examination. to clear the papers in which he/she fails to qualify (irrespective of the number of such papers). f) Examiners shall examine students orally during the Practical examination and take cognizance of their performance when marking their papers. unless specified otherwise. inclusive of the first attempt. he/she will not have any further claim to continue the studies and that his/her name may be struck off the rolls. and specific recommendations will be forwarded to the Registrar for getting approval of the competent authority. 11. d) The Dean of the Faculty will examine application for mercy chance with proper justification and a written undertaking given by the student. a student may be considered for grant of one last mercy chance. wherever applicable. Each theory paper or practical examination shall be construed as a separate paper. including sessional marks.b) A candidate who fails to appear in the annual examination or having appeared in the Annual examination fails to pass in any subject(s) as prescribed for the examination. shall be promoted to the next year of study. may be allowed to appear in the remaining subjects in the Supplementary examination. g) A student shall not be declared to have passed the examination unless he/she secures at least 50% marks in each of the subjects separately in the theory as well as practical examinations. c) A candidate will be given a total number of three attempts. including sessional marks. In exceptionally hard cases. The undertaking would be to the effect that in case he/she does not clear the backlog in this final attempt. . Promotion to next class: a) All students securing at least 50% marks in each of the subjects separately in the theory as well as practical examinations.
as a regular student. and secures at least 50% marks in the aggregate. secured by the candidate in the II to IV year examinations. passing the first year examination within two academic year. and successfully completing all the requirements of the programme of study within seven years from admission. he/she will have to join I year again and register only in the backlog papers. and he/she does not succeed in clearing the carry over papers of I year along with the regular papers of II year. d) A student who has been promoted as per clause (b) above and fails to clear the backlog in the year to which promoted provisionally. will be required to rejoin the year to which the carried over papers belonged. However. Classification of successful candidates: a) The result of the successful candidate shall be classified at the end of the final year examination on the basis of the aggregate of all subjects. •He/she has obtained a minimum of 60 per cent marks in the aggregate. if any.b) A student who fails in one or two subjects (separately in theory and practicals). He/she will be registered only in those subjects in which he/she could not secure the minimum pass marks of the last examination. Ist Division: 60% and above 2nd Division: 50%-59% b) Candidate securing 75% or above marks in any subject(s) and have passed in all the subjects in a year in first attempt shall be declared to have obtained Distinction in that subject(s). including qualifying courses. theory and practicals. as indicated below. e) Promotion to the next higher class will be considered subject to rules relating to the maximum period of stay at the University. 12. viz. c) A student shall be eligible for award of Gold Medal subject to the following criteria. •He/she has passed all examination. as stated in (i) above. For instance. . in first attempt. may be provisionally promoted to the next higher class. c) A student who fails in more than two subjects will have to repeat the year of study and clear it within the prescribed span period. if a student was provisionally promoted to II year with a carry over of two papers of I year. •He/she has secured the highest marks in aggregate of examinations of all the years of the programme of study. such a student shall have to clear these subjects in the year to which thus promoted provisionally.
and must complete the full course of study within seven years from their admission to the first year of the course. exceptions to the 7 years rule may be made in the following cases: A candidate who fails in only one subject in B. Pharm. Pharm. IVth year Annual examination but has completed the maximum span period of 7 years. but has completed the span period of 7 years. Pharm.13. may be allowed readmission in B. IVth year in the concerned subjects as a hard case. as a special case. However. Such a student shall have to appear in sessional tests. Span Period: Students must pass the first year examination within two academic years. IVth year examination. . practicals internal assessments in the concerned subject. may be allowed to avail one more chance in the subject concerned. A candidate who qualifies in at least one subject but fails in half the number of subjects of B. and will be required to clear the backlog in the Annual and Supplementary examination.
SYLLABUS Bachelor of Pharmacy FACULTY OF PHARMACY JAMIA HAMDARD .
B-PHARM IST YEAR .
their applications in the preparation of tinctures and extracts. objectives of size reduction. solvents. Various methods and equipments employed for size separation e. desiccation and exsiccation. study of evaporating stills and evaporating pans. Study of one monograph from the latest edition of Indian Pharmacopoeia. powders and capsules. organoleptic additives. sieving. heat transferring evaporators. elixirs. principles. 2. semi continuous & continuous type. Metrology Imperial. sublimation. Demonstration of equipments (working procedure) for i) Size Reduction and size separation ii) Mixing and homogenization iii) Clarification and filtration iv) Evaporation v) Distillation vi) Percolation Books Recommended: 1. bases. 5. vapor compression evaporators and evaporation under reduced pressure. filter aids. mucilages and liniments. Size reduction and Size Separation Definitions. and International Pharmacopoeia. different methods of size reduction. theory and factors affecting filtration. Pharmacy Profession Pharmacy as a career. surfactants. double cone mixers.. sigma mixers. B. Extraction and Galenicals Extraction processes and study of percolation and maceration and their modifications. glycerine. Clarification and Filtration Definitions. turbo dispensers. syrups. 2. suppositories. 4. Study of different types of mixers used in pharmaceuticals like planetary mixers. Mixing and Homogenization Theory of mixing: solid-solid.I. weights and measures. U.. sand filter. factors affecting size reduction. Colloid mill. membrane filters. liquid-liquid and semisolid mixing. microscopic methods. Introduction to Pharmacopoeias with special reference to Indian Pharmacopoeia. efflorescence and its importance.S. vehicles. solid-liquid. injections. Distillation: Importance of distillation in Pharmacy. metric and S. 7. 6. Triple roller mill. Remington's Pharmaceutical Sciences (Latest Edition). Preparation of following classes of products involving the use of calculations in metrology (at least 2 products from each category wherever applicable): Aromatic waters. g. Pharmaceutical Additives Diluents. tablets. Heat Processes Evaporation: Factors affecting evaporation. vacuum filters. batch. and selection of filters. conventional and novel delivery systems. sedimentation. Centrifugal type filters. 9. fluid energy mill and disintegrator. filter press. 8. earlier period. 2.P. interconversion 3. methods of distillation. Introduction to Dosage forms Classification of solids. evaluation of pharmacy profession. polymers and their applications. leaf filters. semisolids and liquid dosage forms. laws and factors affecting energy requirements. centrifugal elutriation. types of filter media. study of hammer mill.Paper BPH 01 PHARMACEUTICS -I INTRODUCTION TO PHARMACY (THEORY) Total Teaching Hours: 50 1. spirits. The Extra Pharmacopoeia-Martindale (Latest Edition). pressure filter. 3. PRACTICAL Total Hours 100 1. Equipments like gravity filter. middle to modern ages. . lotions.. solutions. edge filter. continuous rotary drum filter. Brief introduction to freeze drying.P. principles of size reduction.
condensation. Heat transfer Modes of heat transfer. chemical. fire extinguishers. Blowers-Compressors. Flow controls: Plug cock.properties and uses of steam. chemical. equipments. globe valves. Measurement of fluid flow: Principle. plastics. refrigeration current cycle and equipments employed for largescale refrigeration. 4. 2. evaluation of individual film coefficient. asbestos. electrical fire and dust hazards. materials and energy balances. causes. 5. study of factors like physical. Fuels .Jain and S. Introduction Introduction to unit operation and pharmaceutical engineering. gases. vapor liquid equilibrium relationship.volute and centrifugal pumps. mechanical and economical. Measurement of pressure: Manometers. 4.solid. automatic regulating valve. gate valves. methods of increasing and decreasing humidity. safety requirements. nickel and alloys. pressure reducing valve. rubber. evacuators 6.concept of film overall coefficient. Suitability of different materials for different plants i. lagging. Flow of fluids Fluid static and dynamics. Azeotropic and zeotropic mixture.Stefan Boltzmann law. 8. laws of conservation in fluid flow. Concept and requirement. application and types. weirs. humidification and dehumidification. Ferrous metals -Cast iron. Types of flow. zinc. OHTC. Environment control and effluent treatment. unidirectional valves. Non-metals glass. Reynold's number and its significance. stoneware. and construction of venturimeter. aluminum and alloys. rotary pumps . ceramics and enamel. HETP. heat transfer coefficient.copper and alloys. steam heated heat exchanger.e. accident records. basic laws. Non-ferrous metals . timber. and positive displacement meter . friction losses. liquid. Air conditioning: Theory of air conditioning. Pumps: Reciprocating pumps. steam traps. Paper BPH 02 PHARMACEUTICS -II UNIT OPERATIONS (THEORY) Total Teaching Hours: 50 1. silver. phase diagrams. basic equations. Convection. lead. heating media. positive displacement pumps.Sharma: The theory and practice of Professional Pharmacy Indian Pharmacopoeia (Latest Edition). Environmental Pollution and safety hazards Mechanical. screw conveyors and pneumatic conveyors.N. cooling towers. steam distillation. Humidity: Determination methods. Pharmaceutical Plant Construction Selection of materials for pharmaceutical plants. and water hammer. steel. Distillation Theory of distillation. distribution of velocities in a pipe. chain conveyors. volatility and relative volatility. heating by electricity. 3. Corrosion : Types.J Carter: Tutorial Pharmacy Cooper and Gunn’s: Dispensing Pharmacy N.K.current meter and disc meter. 7. Rota meter. . slate brick. S. Steam as heating medium . Radiation . Rectification and construction of columns. Application of humidity control in pharmaceutical industries. chromium. Refrigeration and Air Conditioning Refrigeration: Theory of refrigeration.3. stainless steel. theories and methods of prevention of corrosion. 5. concrete. 6. pitot tube. molecular distillation. lagging. orifice meter. enthalpy composition diagram and determination of number of theoretical plates. tin. pipe fittings and joints. Conveying of Solids Belt conveyors.
J. tray dryer. flow. Lettering and dimensions. Peters: Elementary Chemical Engineering 6. determination of factors affecting rate of drying. suppersaturation theory and its limitations. crystal growth. Efficiency of a simple distillation unit and effect of insulating materials on the efficiency. Carter: Tutorial Pharmacy 7. Determination of hardness of water. Calibration of rotameters. 5. Estimation of overall heat transfer coefficient in distillation unit. Factors affecting liquid displacement in air lift pumps. Banchero: Introduction to Chemical Engineering 3.convection type. drying of dilute solutions and suspensions . Study of Reynold's number and flow of fluids. rate of drying. 10. . freeze dryer. Lauer & Heckmann: Chemical Engineering Techniques 5. level and vacuum and their measurements. Drying Theory of drying .principles. Effect of number of balls and speed of ball mill on the grinding rate in ball mill. Effect of thickness of filter media. 16. equilibrium moisture content. Walter L. 17. Modern methods of prescribing and common Latin abbreviations. 11. Determination of humidity by Psychometric method and physical . PRACTICALS Total Hours: 100 Experiments based upon theoretical portion preferably on the following 1. 14. equilibrium moisture content. Automation in drying process.Richardson and J. Determination of flow rate by Orifice and Venturimeters. Determination of efficiency of a steam distillation unit. 9. 3. hydrostatic pressure. Crystallization Characterization of crystals and factors affecting them. Effect of driving fluids on efficiency of ejector pumps. fluidized bed dryer. 11. 8. radiant heat dryers. 13. temperature. size of filter media etc. 10.Bhatt: Elementary Engineering Drawing. Calibration of pressure gauge with manometers. isometric projections. Elementary engineering drawing. 7.drum dryer. drying of solids . Orthographic projections.D. Elements of computer aided manufacturing (CAM). oven dryer. Prescriptions Reading and understanding of prescriptions. Paper BPH 03 PHARMACEUTICS III DISPENSING PHARMACY (THEORY) Total Teaching Hours: 50 1. spray dryer. single vacuum.M. S. tanks.9. study of various types of crystallizer.method. Suspension of lacto . nucleation mechanisms. N. Lines.J. Drawing instruments and their uses. 2.F. 4. agitated batch. cacking of crystals and its prevention.bacilli and evaluation. conversion of pictorial views into orthographic views. Autoclave Process Control System Process variables. Comparison of single stage and multiple stage extraction in solid-liquid extraction. circulating magma and crystal crystallizer. Rate of drying. 12. Books Recommended: 1. on filtration rate. pressure. 6. Badger and J. Swenson Walker. Freeze drying of a solution of antibiotic. Perry: Handbook of Chemical Engineering 4. rotary dryer. vacuum dryer. Coulron: Chemical Engineering 2. Elements of automatic process control systems. tunnel dryer.T. 15.
indications. their merits and demerits. Study of the following classes of patent and proprietary products. Emulsions and Suspensions Emulsions – Definition. Total Parenteral Nutrition. packaging. preparation. suppositories. PRACTICAL Total Hours 100 1. adverse drug reactions. Pastes. packaging and evaluation of tablets. Student's Orientation Introduction to the laboratory equipment. flocculated and deflocculated suspensions. Sterile Dosage forms Definition. chemical and therapeutic incompatibility. . classification of powders. 9. incompatibilities. merits. dentifrices and cachets. ENT preparations. capsules. packaging. 7. Students should be trained in patient counseling by discussing specific problems in major classes of patent and proprietary products. equipments. (d) Antiemetics. preparation methods. solubility and methods of increasing solubility. mixtures. merits and demerits. Semi-Solid Dosage forms Ointments: Classification of ointments and ointment bases. formulation and stability of suspensions. (b) Antiamoebic drugs. Handling. storage. emulsions. preparation. displacement value. compounding. 3. Current Patent and Proprietary Products A study of current patent and proprietary products. sex and surface area. suppositories bases. alcohol dilutions. insufflations. Suppositories and Pesseries: Types. dose and packing of (a) Antihypertensive drugs. pastes.2. labeling and storage of ointments. percentage calculations. displacement value of suppositories. merits and demerits. General requirements of sterile dosage forms. 6. packaging and evaluation of capsules. demerits. Posology Factors influencing dose. packaging. representing the following classes of products. merits and demerits. Elementary study of the formulation characteristics of the following types : Injectable preparations. types. Introduction to Ayurvedic/Unani Tibb Dosage forms. Jellies. and w/w. labeling instructions. Capsules Hard and soft gelatin capsules. weighing methodology. storage. 13. tablets. uses and classification of emulsifying agents and preparation and stability of emulsions. dusting powders. general instructions and handling of prescriptions. use of suspending agents. miscellaneous products 3. 5. ointments. storage and dispensing of sterile dosage forms. should be compounded and dispensed: Powders. Suspensions – Definition. v/v. preparation. contraindications. Labelling instructions and precautions while dispensing various dosage forms. creams. Storage and packaging of liquid formulations for internal and external use. storage and packaging of powders requiring special consideration like effervescent powders. % w/v. 11. use of alligation methods. Tablets Types of tablets. proof spirit. types. 4. Calculations of doses on the basis of age. merits and demerits. types and identification tests. 10. isotonic solutions. (c) Antihistaminic. lotions and liniments. merits and demerits. labeling and storage. available dosage forms. 8. Factors governing selection of an ideal ointment base. Liquid Dosage forms Preparation. (e) Antacids and ulcer healing drugs. dialysis fluids. Poultices: Formulation. Compounding and Dispensing of Prescriptions At least 50 prescriptions. bulk powders. 12. ophthalmic and ENT products. 2. Incompatibility in Prescriptions Physical. Metrology Reducing and enlarging recipes. generic and selected brand names. mEq units. Powders Types of powders.
of India. nomenclature of isomers and determination of configuration. 2.pp-443-464. Boylan: Encyclopedia of pharmaceutical Technology. chloroform. denatured alcohol. Stereochemistry Stereoisomerism. Merck. Vallabh Prakashan. (g) Respiratory drugs. 4. carbon tetrachloride. inductive and electromeric effects. New Delhi. ethylene glycol. methylated spirit.D. Aliphatic & Alicyclic Hydrocarbons Alkanes. 3. 3. Rx list internet: Drug Index: www. Paper BPH 04 PHARMACEUTICAL CHEMISTRY I ORGANIC CHEMISTRY (THEORY) Total Teaching Hours: 50 1. 10. Marcel Dekker Inc. 11. nomenclature. Asgar Ali and A.Khar and Pratibha Nand: Dispensing Pharmacy. 2nd Edition.CBS Publishers. R. 7. Remington’s Pharmaceutical Sciences. Virtual Library: Medicine-www. geometrical isomerism. Mahamuni: Pharmaceutics-II (Theory and Practise of Dispensing Pharmacy). secondary and tertiary alcohol. mesostructures. 4. MIMS/CIMS 13. 4th Edition. glycerol. alkynes. acetaldehyde and their polymers. Popli and Sharma: Current dispensing practices. Nanda. optical activity. methanol. 5. conformational analysis. Basic Principles and Concepts of Organic Chemistry Polarity of bonds and molecules. Diasteriomerism. (h) Antibiotics. resonance. proof spirit. racemic modification and resolution of recemic mixtures. New York. Delhi. Vallabh Prakashan. Bajaj: Introduction to Pharmaceutics-II. Drugs Today 12. Legal and Ethical aspects of Dispensing and compounding of prescriptions The students should be trained about these aspects and evaluated by questionnaire. Rxlist.Prescribing of Drugs .edu/cliniweb/wwwvi. Cooper and Gunn: Dispensing for pharmaceutical students. Aldehydes and Ketones Formaldehyde. alkenes. solvent ether. Delhi.com. 5. divinyl ether. James Swarbrick and James C. 14. 8. Indian Pharmacopoeia. New Delhi. specification of R and S.K. Ethers Thioethers. enantiomers. preparation and reactions/properties of the following groups of compounds (including mechanism of reactions wherever necessary). 2. Vol. Aliphatic Alcohols (i) Primary. (i) Analgesics and (j) Antipyretics. Govt. cycloalkanes.com/ pubs/manual. trichloroethylene and halothane. Dehydrohalogenation of alkyl halides. Mittal: Textbook of Pharmaceutical Formulation. Delhi. Gupta and S. CBS Publishers. B. 6.M. A. D and L configuration. Bayer strain theory 4. dipole moment. intramolecular and intermolecular hydrogen bonding. ethanol. 6. Alkyl Halides SN1 and SN2 reaction mechanism and stereochemistry. E and E2 1 mechanism.(f) Anti-diarrhoeals and laxatives. 12th Edition.ohsu. Classen . Structure.12. CBS Publishers. it’s nature of formation. 9.K. Books Recommended: 1. Merck Manual: www. acids and bases. 7. Prescription Reading: Minimum of 20 prescriptions from the clinical practice 5.S. mechanism of aldol condensation. (ii) Di and trihydric alcohols: glycols. anaesthetic ether. propylene glycol and dimercaprol.
aspirin and paracetamol. sulphate. Kogakusha. Allyn and Bacon lnc. acylhalides. lactic acid.T.L. lactides. diamines. ethyl nitrate. 11. synthesis of carboxylic acids. tartaric acid. malic acid. New Delhi. 3. Mannich reaction. 6. acetic acid and their derivatives. 4. ß-unsaturated carbonyl compounds (conjugate addition) including Michael and Diels . quinine. tests for identity. ascorbic acid. Sources of impurities in pharmaceutical substances Importance of limit test and general principles and procedure for limit tests of chloride. Hofmann’s rearrangement. Pharmaceutical aids and necessities Acids. Boyd: Organic Chemistry. Paper BPH 05 PHARMACEUTICAL CHEMISTRY II INORGANIC MEDICINAL PHARMACEUTICAL CHEMISTRY (THEORY) Total Teaching Hours: 50 1. valeric acid. Ale English Language Book Society and Longman Group Limited. Orient Longman. glucose. L.Publishers. caffeine. dextropropoxyphene hydrochloride. Di and Tricarboxylic Acids Oxalic acid. glycosides. glutaric acid.I. differentiation of 1 2° and 3° amines. butyric acid. direct and indirect alkylation of esters and ketones.condensation. S. °.B. USA. lactones and gluconic acid. 7. cramiphen hydrochloride. 9. P. 4. 2. Pandeya: A textbook of pharmaceutical organic chemistry (Mechanistic approach) Vol. dicyclamine hydrochloride. I. iron.hydroxy and ß-alkylamines. McGraw Hill. proteins and amino acids. A.Textbook of Pharmaceutical Chemistry. Delhi. Hendrickson.1. thiambutosine. decarboxylation of ß-ketoacids and malonic acids. London. alkylation of carbonyl compounds via enamines. lead and heavy metals. cyclamic acid. New Delhi. urea and ureides. Saturated Monocarboxylic Acid s Formic acid. malonic ester. Witting reaction. J. bases. Identification of organic compounds based on solubility and functional group test. PRACTICAL Total Hours: 100 1. . Tokyo. Finar: Organic Chemis try. sucrose. Morison and R. Sykes: A Guide books to mechanism in Organic Chemistry. Test for identity of selected drugs: atropine. Atherden: Bentley and Drivers . acetoacetic ester. water and pharmaceutically acceptable glass. 10. Lassaigne's test for nitrogen. arsenic. 8. antioxidants. propionic acid. 12. Organometallic compounds Grignard’s reagent their preparation and synthetic applications. buffers.M.A. 3. maleic acid and fumaric acid. Cram and C. 2. mustine hydrochloride.N. palmitic acid and stearic acid. Vol. synthesis of ketones. S. Benzoin condensation. R. sulphur and halogens. a.G.N. carbohydrates. assay procedure and pharmaceutical uses of compounds covered under following headings: 2. succinic acid and their amide and imide derivatives. Performance of qualitative test for alkaloids.J.Alder reaction. The following topics will be treated covering an outline of methods of preparation. Varanasi. 5. Hammond: Organic Chemistry. Books Recommended 1. malonic acid. citric acid and adipic acid. Ali: Practical Pharmaceutical Chemistry. Boston. Limited. Cannizzaro’s reaction. Siddiqui & Mohd. ß. Carbanions Reactions involving carbanions. Aliphatic amines and related compounds Alkylamines. Oxford University Press. D.S. Perkin’s condensation.
Roger's Inorganic Pharmaceutical Chemistry. E. copper sulphate. drying. zinc. Introductory Pharmacognosy Historical development. Varanasi. morphological. type of soils. physiological acids-base balance. Production Factors Factors involved in the preparation of herbal drugs for market from cultivated and wild sources including collection. New Delhi. Limit tests for impurities in pharmacopoeial compounds. Ali: Text book of Pharmaceutical Inorganic chemistry. 6. official and unofficial drugs. Siddha and Allopathic systems practiced in India. Radiopharmaceutical used in medicine Therapeutic application of isotopes.N. . Cultivation of herbal drugs. Books Recommended 1. polyploidy. 3. Govt. Wilson: Inorganic Medicinal and Pharmaceutical chemistry. 5. Paper BPH 06 PHARMACOGNOSY I PHARMACEUTICAL BIOLOGY (THEORY) Total Teaching Hours: 50 1. O. strong and weak iodine solutions. S. Animals. selenium. electrolyte combination therapy. Pandeya: A Textbook of inorganic medicinal chemistry. protective and absorbents. 5. of India. Dental products Anticaries agents and dentifrices. antidotes. iron.O. J. organized and unorganized drugs. Soine and C. hydrochloric acid. Delhi. boric acid. 4. diagnostic application of isotopes. ammonium chloride. PRACTICAL Total Hours: 100 1. 4.Publishers. sodium sulphate. 2. Ayurveda. Major intra and extra cellular electrolytes Major physiological ions. 2. sodium thiosulphate. Pharmacopoeia of India. CBS. sodium hydroxide. 2. Role of herbal drugs in national economy. M. chlorinated lime. 3. sodium chloride. electrolytes used in acid-base therapy. 7. Oxford. pharmacological. 3. 4. fertilizers. Gastrointestinal agents Acidifying agents. Unani. PA. 6.3. Essential and trace ions Copper. mutation and hybridization in medicinal plants. Roche. Homeopathic.M. inorganic matter. ferrous sulphate. sodium bicarbonate. potassium permanganate. University press. plant hormones and their applications. Classification of crude drugs Based on alphabetical. Factors influencing variability in drug activity. plant tissue culture and marine sources. expectorants and emetics. sodium carbonate.H. Philadelphia.G. antacids. Miscellaneous Inorganic Pharmaceutical agents Inhalants. Lee Febiger. chemical and taxonomical methods. saline cathartics. Topical agents Antimicrobials and astringents. 8. S. L. Block. Significance of Pharmacognosy in various systems of medicine viz. respiratory stimulants. electrolytes used in replacement therapy. Standardisation of sulphuric acid. Atherdon. Definition of drug Sources of crude drugs viz. Quantitative analysis -assay of the following compounds will be done: solution of ammonia. Herbs. 5. sulfur and iodine. T. Ministry of Health. modern concept and scope of Pharmacognosy. Bently and Drivers: Textbook of pharmaceutical chemistry. 9. storage and transport methods. Delhi.
phloem fibres. T. Jean Brunet: Pharmacognosy and Phytochemistry. 8. Alginic acid. calcium oxalate crystals. 2. London. stomata. leaf. 4. Monocot).M. Delhi. 2. bark. trichomes. fruits. Papilionaceae). Mushrooms. 2. Yeast. Microscopical studies of basic tissues. glycosides. Rutaceae. ii) Fungi: Eumycetes (Ergot. Papaveraceae. Gokhle: Pharmacognosy 6. Mimosaceae. flavonoids. New Delhi. Colophony). iridoides and amino acids. 4. resins and proteins. physiology and related sciences. polysaccharides. Apiaceae. CBS. Medicinal Plants 7. clearing agents. fruits. Root (Dicot.6. ii) Study of human skeleton. P. Purohit and S.. phenolic compounds. Bombay. Dutta: Botany for Degree students. iii) Neuromuscular transmission. Varghese Co. Anatomical terms in relation to parts of the body.and triterpenes. Brady and S. Wallis: Textbook of Pharmacognosy C. Diatoms. Study of diagnostic characters of families mentioned in the theory. ii) Physiology of muscle contraction. Books Recommended 1. J. classification and chemical tests of: Carbohydrates. glycosides. saponins. mono-. Antibiotics. chemomicroscopic reagents.B. iii) Gymnosperm: Pinaceae (Turpentine. Convolvulaceae. alkaloids. Microscopic preparation. Acanthaceae and Euphorbiaceae. Scrophulariaceae.K. seeds and monocot and dicot stems. 9. anatomical structures of bark. tannins. seed.K. 8. V. Rubiaceae. Lamiaceae. L. Phytoconstituents of medicinal importance Introduction. Staining and surface preparation.S. PRACTICAL Total Hours: 75 1.R. ii) Genetic control of cell function. v) Pteridophytes: Male fern. Solanaceae. Principles of plant classification Diagnostic features and medicinal significance of important plants with special reference to: i) Algae: Rhodophyceae (Agar. iv) Angiosperm: Apocynaceae. Tissues of the Body i) Types of tissues and their functions. carotenoides.E. Paper BPH 07 HUMAN ANATOMY & PHYSIOLOGY (THEORY) Total Teaching Hours: 75 1. A. Techniques in microscopy Details of mountants. . Asteraceae.. Membrane i) General principles of membrane permeability transport. Publishers. Mukherjee: Quality Control of Herbal Drugs 5. Carrageenan and Cetraria).B. 7. Harborne: Phytochemical Methods. system and organs. 4. stem (Dicot. Tylor. C. 3. tannins. ii) Mechanisms and electrophysiology of membrane. di. steroids. Robbers: Pharmacognosy. General chemical tests for alkaloids. Leguminosae (Caesalpinaceae. Study of morphological and histological characters of crude drugs Ergastic cell inclusions. leaves and roots. Introduction i) Definition and scope of anatomy. K. Ali: Text Book of Pharmacognosy. starch.P. and Lycopodium). Chapman and Halls. New Delhi. Gnetaceae (Ephedra). Kokate. AC. Oxford University Press.E. Mohd. 3. Monocot).B. Cell i) Structures and their functions.B. 3.
their control by hypothalamus. correction of acidosis and alkalosis. synapses. iii) Circulation (Pulmonary. Abnormalities of adrenocortical secretion. 12. ii) Physiological consideration of urine formation and factors controlling it. body buffer systems (bicarbonate. iv) Regulation of body fluid constituents and their volumes. secretion and regulation of thyroid hormones and their functions. v) Blood composition and functions. 6. Adrenocortical hormones. diseases of the thyroid. Cardiovascular System and Blood i) Structures and functions of heart and blood vessels. v) Acid-base physiology: Hydrogen ion production. ovulation. ii) Spermatogenesis. 8. ii) Heart sounds. iii) Study of surgical instruments 2. regulation and functions. Nervous System i) General anatomy and physiology of neurons. phosphate. lactation. Blood pressure and its regulations. ii) Central nervous system. Physiology of sleep. their physiological functions. menstrual cycle. iii) Transportation of gases. iii) Puberty. v) Reflex arc. Urinary System i) General disposition of organs of excretory system. iii) Liver and pancreas. menopause and sex hormones 11. Formation. Placental and Foetal). Sensory and motor pathway. ECG. 7. Rh factor. Parathormone and calcitonin and control of calcium metabolism. iv) Hypoxia. Coronary. its various parts and their functions. ii) Physiology of digestion.5. Special Senses i) Physiology of hearing. 10. Limbic system. iv) Pregnancy. PRACTICAL Total Hours: 100 1. Endocrine System Introduction to endocrinology and general mechanisms of hormone action: Pituitary hormones. respiratory and renal regulation of acid base balance. (Immune mechanism). Respiratory System i) Gross anatomy of respiratory passages. iv) Lymphatic system. ii) Study of models of organs of various body systems. Human Anatomy & Physiology i) Study of human skeleton and bones. 9. CSF. Cardiac cycle. their chemistry. ii) Structure and functions of skin. taste. Histology i) Handling of microscope ii) Identification of various tissues . iii) Micturition. Anoxia. blood transfusion. iv) Autonomic nervous system. artificial respiration. Dyspnoea. neurohumoral transmission. Digestive System i) Gross anatomy of the alimentary canal. iii) Regulation of body temperature. iii) RAS. ii) Regulation and mechanism of breathing and pulmonary function test. vi) Blood groups. Cerebral. Reproductive System i) Structure and function of male & female reproductive organs. secretion. smell and vision. and proteins). reproductive cycles. conditioned and unconditioned reflexes. Pancreatic hormones and their metabolic effects and pathophysiology of diabetes mellitus.
Goyal. 2. Recording of body temperature by various techniques. Practical 1.A. Dacie and S.3. Norman Joels and Samson Wrights: Applied Physiology. Sujit K. Lewis: Practical Haematology. 2. 6.C. . Haematology i) Estimation of haemoglobin ii) Total RBC count iii) Total WBC count (TLC) iv) Differential leukocyte count (DLC) v) Platelets count vi) Determination of blood group and Rh factor. Guyton: Textbook of Medical Physiology. 5. vii) Determination of ESR (demonstration) viii) Determination of blood clotting and bleeding time ix) Identification of plasmodium species in the human blood 4. Recording ECG and its interpretation. Ramesh K. Patel and Shailesh A. Recording and interpretation of EEG. Arthur C. Cyril A.W. Keele. Kathleen J. Shukant R. 6. Cardiovascular System Determination of blood pressure by palpatory and auscultating methods.W. Nervous System Study of reflex action. Sir John Y. 3. 3. Chatterjee: Human Physiology. Physiology and Biochemistry. Respiration Pulmonary function test using spirometer.W. Shah: Practical Anatomy. M. C. T. Glenister and Jean R. Erie Neil. Apte: Experimental Physiology. Books Recommended: Theory 1. Chaudhuri: Concise Medical Physiology. Ross: Anatomy and Physiology for Nurses 5. Wilson Ross and Wilson: Anatomy and Physiology in Health and Illness 4. Natyar M.
B-PHARM IIND YEAR .
Differentiation. 13. 10. . Double integrals. Lim Sin o/o. Higher order derivatives. 4. log. Significance tests-test of significance and chi-square test of significance. Use of log-log graph. Condensation of the data collected. Pictorial representation of frequency distribution in histograms and frequency polygons. 14.Paper BPH 08 PHARMACEUTICAL MATHS AND BIOSTATISTICS STATISTICS AND CALCULUS Total Teaching Hours:-50 1. 23. mean deviation and standard deviation. maxima and minima. 17. 11. Differential coefficient of a function. Limits of algebraic functions. 8. as an area . Books Recommended 1. 30. Prasad: Differnetial Calculus. Linear differential equations with constant coefficient. 4. Integration of sum and difference of two functions. 3. 33. No R. Interpolation. derivative of product of two functions-generalizing it for the product of 3 functions. 26. Simultaneous differential equations. Derivative of function of a function. Parametric functions. Correlation between two variables. Derivative of trignometrical functions and inverse functions. 16.S (x. Functions. Derivation of formulae of integration from derivative formula. Probability. 18. Derivative formula of sum and difference of two functions generalizing it for more than two. The relationship of integration to summation.y) dydx over a particular region and its interpretation. Definite integration. 7. axioms on limits. 6. 25. 2. Derivative by method of substitution. R and B (beta) functions. 27. area of circle. various forms of distribution tables. Prasad: Integral Calculus. Approximate values. integration by parts. Tangent and normal. partial derivative. Ordinary differential equations of the first order. 9. Partial derivatives. 20. Measures of central tendency. derivatives of quotient of two functions. Derivative by method of substitution. 24. Total differentials and total derivatives. Croxton and Frerick: Statistics. Measures of dispersion-range. derivatives of xn . 5. 22. 29. higher order. velocity and acceleration. 32. 28. coefficient of variation. 5. 12. S. Yule and Kendell: Statistics. 15. 19. 3. interpretation of definite integration. Integration by substitution. Ayers Mathematics and Stats for Students of Pharmacy. 21. of trig. implicit function. 31. 2.
heat. types of reactions and their application. tetanus anti-toxin and diagnostic biologicals. BCG vaccines.EMP and TCA pathways.g. Aseptic Technique Designing of aseptic area . identification. BP and USP. staining and enumeration. equipments. Immunoassay.solids. cultivation. factors affecting the microbial spoilage of pharmaceutical products. vitamins and amino acids. Control of microbial contamination during manufacture General aspects-environmental cleanliness and hygiene. cellular immunity. moulds. bacterial metabolism . dressings. Microbiological Standardization Microbiological methods for standardization of antibiotics.Physical. Sterilization methods and Principles Methods of sterilization. viral vaccine. rickettsial vaccines. sterility indicators. toxo ids. gaseous. sources and types of microbial contaminants. evaluation of microbial stability of formulations.. Sterility testing of sterile surgical devices. small pox vaccine. Preparation and standardization of immunological products. process design. general microbiological techniques. chemical. components. liquids. antibodies.P.. 5. Sterility testing of parenteral products . poliomyelitis vaccine. its branches and its importance. filtration. dark field microscopy and electron microscopy. isolation and identification. Introduction History of microbiology.organisms. aeration process. quality control and documentation. temperature. Disinfection Classification and mode of action of disinfectants. Large scale production fermenter design and its various controls. assessment of microbial contamination and spoilage.P. antigens. Fermentation Technology Fermentation methods and general requirements.Paper BPH 09 PHARMACEUTICS-IV PHARMACEUTICAL MICROBIOLOGY INCLUDING BIOLOGICAL PHARMACY (THEORY) Total Teaching Hours: 50 1. and U. A brief introduction to Recombinant DNA technology. factors influencing disinfection. Sterility testing of pharmaceutical products Sterility testing of products according to IP. Study of the production of . e. citric acid. 2. light and pH on the growth of micro .S. 7. antitoxins. bacteriological media. disinfectants. 3. Study of different types of phase microscopy. quality of starting materials. haemostats. ophthalmic and other sterile products according to the I. sterilization methods.laminar flow equipments. diphtheria toxoids. types of immunity. Immuunology Introduction. stirring. yeasts. study of media. graft host reaction.penicillins. . dynamics of disinfection. ion. viruses and actinomycetes -nutrition. 4. surgical catgut . phagocytosis. Interferon. antiseptics and their evaluation. Effect of moisture. Bacterial resistance. Examples of the materials sterilized by different methods. Equipments employed in large scale sterilization.P. immunogenetics. General method of the preparation of bacterial vaccines. 6. implants. General classification of microorganisms and study of bacteria. 9. study of different sources of contamination in an aseptic area and methods of prevention. radiation. Microbial spoilage and preservation of Pharmaceutical products Types of spoilage. 8. 10. absorbable. surgical ligatures and sutures. Evaluation of the efficiency of sterilization methods. B. Salient features of common communicable disease producing microbes. Assessment of a new antibiotic and testing of antimicrobial activity of a new substance. clean area classification. fungal diastase and dextran. privileged graft sites. immune-systems humoral immunity. tolerance. preservation of pharmaceutical products using antimicrobial agents. serum-immune blood derivatives and other products relative to immunity.
litmus milk test.P.g. methods of analysis. Balliere Tindall and Cox: Pharmaceutical Microbiology. Preparation of various types of culture media.latest editions 13. 4. 3. Bacteriophage isolation and characteristics 15. Edward: Fundamentals of Microbiology 15. Sub culturing of bacteria and fungus. 19. Hanging drop slide preparation. Biochemical reactions-starch hydrolysis. Studying of different laboratory equipments and processing.Banker and Christopher T.S. Kinetic and Drug Stability Rates and orders of reactions. Hugo and A.D. 17. 12. Books Recommended 1. Vallabh Prakashan. 2. inclusion compounds. Various staining methods-simple. Microbiological standardization of raw materials.. Cooper and Gunn’s: Tutorial Pharmacy 11. Antimicrobial activity of an unknown compound. Hinsdill et al: Fundamentals of Microbiology. Delhi 16. Blackwell Scientific publications. autoclave. organic molecular complexes. I. Complexation and Drug action Metal complexes. 7. 5. FDA method and chick martin. . 10. hot air sterilizer. Sterility testing-different methods as per IP/BP/USP 8. U. Oxford London. Microbial viable count in a pharmaceutical product and total count of bacteria 11. Gilbert S. W. Prescot and Dunn: Industrial Microbiology. Rose: Industrial Microbiology. 9th ed. 14. 7. e. Studying of the environment micro flora and testing of aseptic area.P.D. Isolation of pure culture of micro-organisms by multiple streak plate technique 6. Grams staining and acid fast staining. Dawson and Mirne: Immunological and Blood products.B. thermodynamic treatment of stability constants. carbohydrate metabolism. PUBMED . 4. 5. B. 2. Japan 10. 12.. Isolation of an antibiotic producer. Evaluation of antiseptic and disinfectants e. Malcolm Harris.. 8.K.pubmed.PRACTICALS Total Hours 100 Exercises illustrating the course contents of theory including: 1. laminar flow. Russel: Pharmaceutical Microbiology. microscopes . 3. Microbiological assay of antibiotics. Normal throat flora. gelatin liquefaction. protein binding. aseptic hood.on Internet (www. Ananthnarayan : Text Book of Microbiology.Jain: Pharmaceutical Microbiology. decomposition and stabilization of medicinal agents. 13. 14. Demonstration of slide preparations of various microorganisms. 2. 18.O.g. Nutrient stabs and slants preparations. accelerated stability analysis. influence of temperature and other factors on reaction rates. 16. incubator. Probisher. refrigerator.com) Paper BPH 10 PHARMACEUTICS -V PHYSICAL PHARMACY (THEORY) Total Teaching Hours: 75 1. nitrate reduction. Pelczar and Reid: Microbiology.. RWC. deep freezer. Peppler: Microbial Technology.P. crystalline structure of complexes. N. Thermal death time determination. Rhodes: Modern Pharmaceutics. 6. 9. B. Remington’s Pharmaceutical Sciences. 9.
10. particle volume. 18. Design. adsorption at solid/liquid interface. solubilization. 6. Determination of surface and interfacial tension Preparation and properties of colloids. Diffusion and Dissolution Steady state diffusion. 1. 2. emulsification. factors affecting flow of powders. 14. mechanical models to illustrate viscoelasticity. 12. fundamental properties of collection of particles like particle size. drug release. factors affecting micelle formation. Coarse Dispersions Suspensions . Determination of particle size by optical method. 13. surface area. foaming agent. Experiments demonstrating the measurement of angle of repose of powders and the factors affecting. Experiments demonstrating the usefulness of solubilizing agent in forming a clear liquid phase of two immiscible liquids (Ternary phase diagram) . Determination of spreading coefficient of organic liquid by stalagamometer. spreading coefficient. Qualitative and quantitative study of adsorption phenomenon. calculations and methods of adjusting tonicity.Introduction. Detergency. 11. procedures and apparatus. settling in suspensions. Viscosity determination of Newtonian and Non-Newtonian liquids by one point and multipoint viscometers. 16. methods for determining particle size. importance in Pharmacy. surface area and particle volume. antifoaming agent. hydrophilic -lipophilic system. mechanism of solubilization. particle number. 5. 6. thixotropy in formulations. 15. Micelle formation. thixotropy. 3.Interfacial properties of suspended particles. Medicinal and pharmaceutical application of surfactants. 17. Any other new experiment that can be included from time to time in support of' the theoretical aspects of the course. 8. diameter of orifice of tube and pressure head. adsorption phenomenon. dissolution. Derived properties of loose powder. Determination of CMC (Critical Micelle Concentration) of surfactants by surface tension methods. surface free energy. 9. Emulsions. complex films. pharmaceutical applications of solubilization. Micromeritics Introduction. 4. quantitative measurement of flow. buffered isotonic solutions. wetting agent.3. 4. diffusion principles in biologic systems. application of rheology to pharmacy. particle shape. Determination of bulk density of pharmaceutical solid. stability. general classification of surfactants. . measurement of surface and interfacial tension. PRACTICALS Total Hours 75 Preparation and properties of simple complexes. 7. Determination of particle size by sedimentation method using and Andreasson pipette. Surface activity. co-solubilization. physical stability of emulsions. Determination of particle size by sieving method and efficiency of screening operation. 5. Rheology Fundamentals of rheology.theories of emulsification. flow properties of powders. conduction and reporting of accelerated testing in studying chemical stabilization against hydrolytic decomposition of drugs. Surface and interfacial phenomenon Surface and interfacial tension.determination of critical micelle concentration. Determination of flow properties of powder through the tube as a function of length of tube. phase equilibria and emulsion formulation. vapor sorption and transmission and thermodynamics of diffusion. factors affecting solubilization. Determination of HLB value of surfactant by saponification method. Buffers Buffer equations and buffer capacity in general. rheology of disperse systems. angle of repose. types of flow. particle size distribution. Methods of measuring viscosity. measurements of tonicity. buffers in pharmaceutical systems. preservation of emulsions. measurement of thixotropy. rheologic properties of emulsions. formulation of suspension. 7. Determination of HLB value by modified Griffin acacia emulsion method. 8. preparation.
T. scope and limitations. Pharmaceutical applications. factors influencing the stability of complexes and applications e. some exercises related to the determination of acids and bases separately and in mixture form. ammonium hydroxide. Beans. ascorbic acid shall also be covered. 5. e. washing of the precipitates. sodium hydroxide. calcium carbonate. sulfuric acid. 6 Gravimetric analysis Introduction.P. 6. redox indicators. preparation and standardization of redox titrants. coprecipitation. Complexometric titrations Types of Complexometric titrations. potassium permanganate titrations. paper and crucibles. Attwood W: Physiochemical principles of Pharmacy. strong bases and weak bases. A.E. e. Varghese Co.Agarwal. phosphoric acid. Other organic precipitants. indicators. filtration. nitric acid. sodium thiosulphate. S.. titrations according to Mohr's and Volhard's methods. A. calcium as calcium oxalate. magnesium as magnesium pyrophosphate. hydrochloric acid. Oxidation & reduction titrations Concepts of oxidation and reduction. direct titration of strong acids. ammonium thiocyanate. classification. aluminum as aluminum oxide.g. Shotton and Ridgeway: Physical Pharmaceutics. 3. specific examples of Gravimetric estimations like barium as barium sulphate. 2. Some official assay procedures.. Beckett and J. supersaturation. Remingtons Pharmaceutical Sciences. boric acid. PRACTICAL Total Hours: -100 1. Martin: Physical Pharmacy. Fajan’s method and Gaylussac’s method. methyldopa and adrenaline acid tartarate. titration of weak acids. ignition.B. Vol. 4. Precipitation titrations Preparation and standardization of titrants like silver nitrate. 5. 2. Diazotisation titrations Different conditions involved in diazotisation of different amines. iodometry and iodimetry.H. CBS Publishers. ceric ammonium sulphate titrations. New Delhi. ligand’s and determination of hardness of water. titration of weak bases.S. acid base equilibria in non-aqueous media. metal ion indicators.Books Recommended: 1. bismuth carbonate. Non-aqueous titrations Theoretical considerations. Introduction Significance of quantitative analysis in quality control. end point determination and pharmaceutical analytical applications such as in the assay of sulfonamides. Acid base titrations Preparation and standardization of acids and bases. H. calciumgluconate. 1 to 4.g. digestion.g. potassium iodate titrations. redox reactions. Some exercises related to determination of oxidizing and reducing agents in a given sample shall be covered. Acid-base titrations Theories of acidimetry and alkalimetry. strengths and equivalent weighs of oxidizing and reducing agents. different techniques of analysis. Preparation and standardization of acids and bases. Pharmaceutical products should be selected for illustration e. K. ephedrine. 8. 3. Bombay.M. Paper BPH 11 PHARMACEUTICAL CHEMISTRY III PHARMACEUTICAL ANALYSIS -1 INORGANIC CHEMISTRY (THEORY) Total Teaching Hours:-50 1. Carless: Advances in Pharmaceutical Sciences. weak acids. bismuth subnitrate.g. Some official assay procedures of boric acid. ammonium and potassium thiocyanate titrations. 4. Some exercises related to the determination of acids & bases. precipitation techniques. Mark Publishing Co. Florence and D. applications in pharmaceutical analysis. 7. . Rajesh Khanna: Physical Pharmacy.
Vitamins. pyrazine and pyrones. 5. J. pyrimidine. properties and actions of Phenols. hypoglycemic agents. diagnostic agents. The Athlone Press of the University of London. Vol I & II. 4. Govt. orientation effects in electrophilic substitution. and structure activity relationship including physicochemical. G. methods of synthesis and important chemical reactions of the following: (i) Five -membered heterocycles Furan. 3. 4. Diazotisation reaction Assay of sulphonamides like wise any two official assays. Ministry of Health. expectorants and antitussives. thyroid hormones and antithyroid drugs. acridines and xanthone. isoquinoline. 6. ceric ammonium sulphate shall be performed.L. antiseptics and disinfectants. Mendham: Vogel's Textbook of quantitative Inorganic Analysis. aryl halides and ketones.M. Delhi. Heterocyclic compounds Study of fundamentals of heterocyclics. Atherden: Bentley and Driver's Text book of Pharmaceutical Chemistry.H. Jenldns. triazole and tetrazole. 4. Aromatic Compounds Structure and resonance of benzene. potassium dichromate. pyrrole. mechanism of electrophilic aromatic substitution. Delhi.P. magnesium and calcium shall he covered. Denney. diazonium salts. sodium thiosulphate etc. imidazole. Hager: Quantitative Pharmaceutical Chemistry. 2. aromatic character. The ELBS and Longman. sulphonic acids and derivatives. uses. Mc.H. iodine. Preparation. Some exercises related to the determination of oxidizing and reducing agents in the sample shall be covered. nucleophilic aromatic substitution. . New York. 2. G. Bassett. Jeffery. steric aspects and mode of action. Pharmacopoeia of India. Complexometric titration Any two official assays done by this method. oxazole.. Paper BPH 12 PHARMACEUTICAL CHEMISTRY IV ORGANIC CHEMISTRY (THEORY) INCLUDING HETEROCYCLIC AND MEDICINAL CHEMISTRY Total Teaching Hours: 50 1. of India. 5. indole. thiophene. Exercises involving use of potassium iodate. London.B. 3. potassium permanganate. amines. (iii) Benz-fused heterocycles Quinoline. Oxford University Press.2. L. pyridazine.GrawHill Company. Gravimetric analysis Determination of water of hydration. some exercises related to Gravimetric estimation of metal ions such as barium. R. Oxidation-reduction titration Preparation and standardization of some redox titrants. potassium bromate. Beckett and J. e. coagulants and anticoagulants. nomenclature. phenanthrene and anthracene. carboxylic acids. Christian. Precipitation titrations Preparation and standardization of titrants like silver nitrate and ammonium thiocyanate.g. Stenlake: Practical Pharmaceutical Chemistry. J. (ii) Six-membered heterocycles Pyridine.The following topic shall be treated covering outlines of synthetic procedures (of selected drugs). pyrazole. 5. 3. Poly nuclear aromatic hydrocarbons Naphthalene. titrations according to Mohr's and Volhard's methods.C.E. A. Books Recommended 1. G. thiazole. nitro compounds.
N.L. lard. Longman. Biosynthesis Formation of primary and secondary metabolites. Lycopodium spore method. asbestos. vein islet number. Atherden: Bentley and Driver's-Textbookof Pharmaceutical Chemistry. Vogel’s Text Book of practical Organic Chemistry. gelatin. chemical test and microscopy of: Cotton. Pancreatin. beeswax. and kieselghur. palisade ratio. lanolin.G. Herbarium Preparation of herbarium sheets and their importance in authentication of plants. S. 5. sensory and chemical characteristic of shellac. Identification of organic compounds and preparation of simple derivatives. Silk and Wool. Cevadilla. Allyn and Bacon Inc.C. Delhi 4. Diastase. New York. Pepsin. 7. Papain Bromalain. acetate hypothesis. Paper BPH 13 PHARMACOGNOSY II GENERAL PHARMACOGNOSY (THEORY) Total Teaching Hours:-50 1. 3. Identification through morphological. Microscopic and chemical tests of the following powdered drugs: i) Leaf: Senna. 6. fungicides. woolfat. stomatal number.N. Drugs of Animal origins Shellac. narcotics. fumigants and rodenticides. Pharmaceutical aids Biological sources. Boyd: Organic Chemistry. health food. Vol. 6. woolfat. honey. mycotoxins. R. 5.. Micrometers and measurement of microscopic characters.Publishers. Pencillinase. 2. 3. spermaceti. 3. Shikimic acid pathway. hallucinogens. beeswax. ELBS and Longman Group Ltd. isoprenoid pathway. PRACTICAL Total Hours:-75 1. Synthesis based on O-and N-acetylation. 2. 2.M. Yeast. London. Longman. Datura and Senna leaves. L. lipids and volatile oils. Finar: Organic Chemistry. honey. Bromalain.. lard. Urokinase. sweeteners. Books Recommended 1. Embden-Maerhoef pathway. cosmetic and photosensitising agents. Cotton. nitration and bromination. Quantitative microscopy of Vinca. Datura . spermaceti. I & II. Enzymes Biological sources. preparation. musk. London.G. Morrison and R. 4. Ficin. Introduction to herbicides. Neem. Boston (USA). F. S. 9. silk.T. Mann & B. cantherides. TCA cycle. wool regenerated fibres. characters and uses of Diastase. Pandeya: A Textbook of Pharmaceutical Chemistry (Heterocyclics & Biomolecules) Vol-II. Saunders: Practical Organic Chemistry. gelatin. Trypsin. Toxic Drugs Study of Allergens. Natural pesticides and Insecticides Tobacco. vein termination number. Plant Products Introduction to plant bitters. I. Quantitative microscopy Determination of stomatal index. lanolin. cochineal. Varanasi. Yeast. kaolin. cochineal. London and New York. Study of Calvin cycle. toxic mushrooms and Indian toxic plants. Ryania. Oxford University Press. Pyrethrum.PRACTICAL Total Hours: 100 1. 8. Hyaluronidase and Stryptokinase. 2. cantharides. Papain. Biosynthesis of carbohydrates. prepared chalk.
Osteoporosis. .leukopenia. shock. filariasis. Handa and M. bronchitis. P. Parkinsons' disease. Varghese Co. Nirali Prakshan.K. Snowdon: Atlas of Microscopy of Medicinal Plants. leukemia. Purohit and S. depression. Alzheimer's disease. . Harborne: Phytochemical Methods. Paper BPH 14 PATHOPHYSIOLOGY. New Delhi. malaria. dementia. Bombay. scope and its branches ii) Teratogenicity and Carcinogenicity iii) Toxicity of heavy metals and their antidotes iv) Management of poisoned patients 4. 7. New Delhi 8. hypertension. typhoid. varicose veins.K. RRL.P. Toxicology i) Definition. metaplasia.atheroma.glaucoma and cataract 3. Kokate. 3. hypertrophy. v) Disorders of the digestive tract -. ii) Disorders of blood cells . sexually transmitted disease. hemorrhagic diseases (thrombocytopenia. Pathophysiology and Clinical Assessment i) Disorders of cells and tissues .B. whooping cough.E. erythrocyte disorders (anemia polycythemia). Gokhle: Pharmacognosy. The Wealth of India. Medicinal Plants 9. aneurysms. P. peptic ulcers.S. fibrinogen deficiency.gastritis. necrosis. inflammation. x) Disorders of eye .schizophrenia viii) Disorders of the reproductive system .S. CBS. 6.rek W. viral hepatitis. CBS Publishers. emphysema. rabies. I-X. tetanus.R. rickettes. Immunological. ischaemic heart disease. cryptorchism ix) Disorders of bone. pain. Robbers: Pharmacognosy. K. Chapman and Halls. cholera. embolism. Culinary Herbs and Spices. allergy 2. purpura) iii) Disorders of blood vessels and heart . Books Recomme nded 1. hyperplasia. Betty P. General aspect of Pathophysiology – Atrophy. arrhythmia.Epilepsy. Brady and S.M. Turmeric ix) Flowers: Clove. Burger's disease. amoebiasis. Delhi. Health Education i) Spread and prevention of communicable disease. V. arteriosclerosis. joints and cartilages .Imp otency.B. 4. surgical.E.AIDS. Coriander vii) Wood: Quassia. Mukherjee: Quality Control of Herbal Drugs. TOXICOLOGY AND HEALTH EDUCATION (THEORY) Total Teaching Hours: 25 1. 10. T. cough.ii) Stem: Ephedra iii) Root: Rauwolfia. irritation. C. meningitis. pancreatitis. leprosy. chemicals. diphtheria.glomerulonephritis.hypoplasia. J. Glycyrrhiza iv) Seed: Nux vomica. Ali: Textbook of Pharmacognosy.tonsillitis. jaundice vi) Disorders of the urinary system . S. cirrhosis of the liver. Mohd. iv) Disorders of the respiratory tract . arthritis. Cinnamon vi) Fruits: Fennel. national family planning program means of contraception (mechanical. tuberculosis. chorea.B. thrombophlebitis. congestive cardiac failure. Kaul: Supplement to Cultivation and utilization of Aromatic Plants. polio-myelitis. measles. influenza. infertility. Publishers. rheumatic heart diseases. L. Raw Materials. Vol. 5. small pox. Tylor. diarrhea.K. viii) Rhizome: Ginger.B. Jammu. neoplasia and general considerations. renal calculi vii)Disorders of the nervous system and special senses . hypoxia. migrain. physical and physiological). ii) Control of population explosion. Jean Brunet: Pharmacognosy and Phytochemistry. bronchial asthma. 2. London. NISCAR. Wallis: Textbook of Pharmacognosy C. Plantago v) Bark: Cinchona. gout. Pune.
A. Kathleen J. iv) Drugs action on autonomic ganglia (ganglionic stimulants. substance P. (Department of Family Planning). 8. PRACTICAL Total Hours: 100 Study of instruments used in experimental Pharmacology. 3. v) Mechanisms of drugs action. scope and branches of pharmacology. viii) Adverse drug effects and their monitoring. Paper BPH 15 PHARMACOLOGY-I (THEORY) Total Teaching Hours: 50 1. ii) Serotonin. v) Neuromuscular blocking agents and centrally acting muscle relaxants. anticholinesterases). i) To record CRC of acetylcholine using guinea pig ileum / rat intestine. Kent. 11. smoking and fixing a kymograph. Handling of laboratory animals. General Pharmacology i) Definition. Hart: Introduction to Human Disease. Park and K. vii) Drug dependence and related conditions. neurotensin. Phillip J. Books Recommended 1. 7. VIP. Influence of routes of administration of drugs on drug response.K. 5. Family Planning and Urban Development. 3. ganglion blocking agents). PAF . vi) Drug antagonism and synergism. drug receptors and cellular signaling systems. Techniques of drug administrations in animals.R. Laurance: Evaluation of Drug activities: Pharmacometrics. P. 4.K. Wilson: Anatomy and physiology in Health and Illness.W. 6. Gupta and D. B. sympathomimetics. iii) Adrenoceptors.C. Plasmakinins. Thomos H. 3. 2. ii) Anticholinergic drugs. Burson: Industrial Toxicology.Principle of Disease. Experiments on isolated tissue preparations. iii) Arachidonic acid metabolites. Drugs in Ocular Pharmacology i) Mydriatic and miotic agents and drugs used in glaucoma. 9. 2. 10. 2. Martha J. 5. Park: Textbook of Preventive and Social Medicine. iv) Renin Angiotensin Aldosterone System. D. Pharmacology of Autonomic Nervous System i) Cholinergic receptors. . H. agonists and antagonists.E. ii) Routes of drugs administration and drug delivery systems. 1. metabolizing enzymes as targets of drugs action (induction and inhibition). Historical development with special reference to India. iv) Basic pharmacokinetic parameters employed in the use of drugs. 4.iii) Immunization – various vaccines. Yash Pal Bedi: A Handbook of Hygiene and Public Health. cholinomimetics. Antihistaminics. toxoids and their uses. Katzung: Basic and Clinical Pharmacology.-I. Miller: Pathophysiology. their bioavailability and biotransformations. ix) Pharmacogenomics. distribution and excretion of drugs. Salunkhe: Modern Toxicology. Willians and James L. cholinergic drugs (parasympathomimetics. Material published by Ministry of Health. J. Mentz: Pathophysiology in Medical Science. Michael N. Vol.E. adrenoceptors blockers. Iatrogenic diseases. 4. iii) Dynamics of absorption. Autocoids i) Histamine.
switch statements.S. hardware. CBS. task swapping.Satoskar and S.Nies and Palmer Taylor. recursion. M.Dale: Pharmacology. Application Software Wordprocessing techiques. iii) Study of competitive antagonism using acetylcholine and atropine.Rall. arithmetic and relational expression. machine languages.Rang and M. 3. operations and types. S. octal. K. 5.R. 7. C. U. Books Recommended: Theory 1.Stitze: Modem Pharmacology.M.Laurence and P. hexadecimal. history of DOS. functions. commands-internal. Determination of intraocular pressure in rabbits. Programming High level languages. . edited. N.Ghosh: Fundamental of Experimental Pharmacology.Stages in programming. input and output. 7. hard disk. variables. 4. 2. Bus.ii) Determination of dose ratio. Practical 1. file manipulations and formatting. Experimental Pharmacology. Program design aims . 8. its types and uses.D.K. functions. folders. Storage devices . Windows and Unix Operating system-definition. symbolic constants. 2. organization.Kamat: Selected topics in experimental pharmacology. Input and output devices. mail-merge. Fundamentals of Computers Computers. Operating System-DOS. v) Determination of PD2 value.P. D. semantics. star and ring topologies. Robert A.Craig and R. Program groups. 6. clipboard. Study of drug absorption in vitro.Kulkami: Handbook of experimental Pharmacology. James Crossland: Lewis's Pharmacology. if-else. items. header files. Theodore W. K. constants. 3.K. 3.1. directories and files. 6. Loops-while.K.K. New Delhi. flow charts. F. computer generations. 5.Sheth. revised. pointers and arrays. Pillai.D. handling of drives. Dadkar and Usha G. Alan S. increment and decrement operators. Goodman Gilman's: The Pharmacological Basis of Therapeutics by Alfred Goodman Gilman. Vol. Number Bases-Decimal. binary. Programming Language ‘C’ Data types. R. 4.Tumer: Screening methods in Pharmacology.Bhandarkar: Pharmacology and Pharmacotherapeutics.S. lan Kitchen: Textbook of invitro Pharmacology. floppy disk. Major differences between DOS and UNIX operating systems Data Transmission and Networks Hardware and software components. 7. Paper BPH 16 COMPUTER APPLICATIONS Total Teaching Hours: 25 1. Pharmacological experiments on isolated preparations by Edinburgh University. stuctures. icons.Prima ry memory. 5. data representation.R. for-transfer statements. syntax. printing setups. 6.E. external. 4. 1968. H.K.Tripathi: Essentials of Medical Pharmacology.N. elements of a computer system. assignment statement. Table 2.Bennett: Clinical Pharmacology. software. Seven layer model.N. Barar: Essentials of Pharmacotherapeutics. 6. iv) Potentiation of acetylcholine responses with anticholinesterases. CDROM. do-while. Windows and UNIX operating systems. Pharmacology Staff.
handling. slide designing. Rubin (Ed. 1977. Programming in C. Gottfried: McGraw Hill Book Co. Wheeler & Co 1986. Books recommended 1. DOS Comands. Formatting of sheets. graphs. First Course. Rajaraman: Fundamental of Computers. graphs. John Sheeley and Roger Hunt: Computer Studies. E. L. MS Excel. R. PRACTICALS Total Hours: 25 MS Office—MS word.): Computer and Communications: Implications for Education. (Schaum’s Series) Programming with C. graphs. 3. IInd Edition. Powerpoint. About spredsheet programs. Presentation Packages.K. workbooks/worksheets. East Economy Edition.. Scidal. 4. picture handling and drawings. Bryon S. Delhi: A. Formulae and functions. 5. Import and export of files/ data. 2. Import and export facilities.J. Academic press. Balagumswamy: Tata McGraw Hill Publishing Co. V. Mathematical equations. and M. .
B-PHARM IIIRD YEAR .
Diuretics. heavy metals. dispensing. 3. functioning and working of clinical pharmacy unit. narcotics. manifestations and treatment of tuberculosis. Drugs in clinical toxicity Introduction. manpower requirements. hospital equipments and health accessories: Nomenclature and uses. requirements. Pharmacists and patient counseling including specific examples 13. . Books Recommended 1. 4. systemic antidotes. external bulk concentrates. Maintenance of records of issue and use of narcotics and dangerous drugs. Introduction to clinical pharmacy practice Definition and scope. hospital formulary system and its organization. epilepsy. procedures for procurement of drugs and supplies from medical stores depot. layout. pathophysiology. Compliance to treatment and role of pharmacist Impact of diseases on drug action 15. layout facilities. 10. bed side pharmacy vi) Prepackaging. Treatment of poisoning due to insecticides. manufacturer. Pharmacy Therapeutics Committee Constitution and functions of Pharmacy therapeutics committee. Drug Information service and drug information bulletin 9. organophosphorous compounds 16. Surgical instruments. Types of hospitals. 14. functions and composition. manpower requirements. space. rheumatoid arthritis. procedure and limits of emergency purchase. equipment. distributor. barbiturates. personnel. Vitamins and Hypoglycemic drugs. 8. production planning. Cardiovascular drugs. Mechanism of drug interactions. 12.Paper BPH 17 PHARMACEUTICS VI PHARMACY PRACTICE (THEORY) Total Teaching Hours: 50 Part I-Hospital Pharmacy 1. general treatment of poisoning. Manufacturing of pharmaceuticals in hospitals Sterile Manufacturing: Large and small volume parenterals. efficient and speedy dispensing of drugs. Non-sterile manufacture: Liquid orals.Drug Interactions with reference to Analgesics. location. diabeties mellitus. 6. 5. local market. OTC Counter Its establishment. facilities. Drug interactions of clinical important drugs Definition and Introduction. Status of health delivery systems in India Definition and role of hospitals in the health delivery systems. hepatitis. Pharmaco-economics Diseases: Etiology. peptic ulcer. Hospital Pharmacy Definition. 7. Remington’s Pharmaceutical Sciences. Gastrointestinal agents. Drug distribution system in Hospitals i) Out patients ii) In patients: Detailed discussion of (a) Unit dose dispensing (b) Floor ward stock system and satellite pharmacy services (c) Central sterile services. Part II-Clinical Pharmacy 11. 2. Medical Stores Objectives. layout and flow chart of material and men. Drug . functions and objectives of hospital pharmacy. personnel and facilities required including equipments. apparatus and other facilities required to achieve safe. common daily terminology used in the practice of medicine. ward stock medicines and emergency drugs. atherosclerosis and hypertension.
stability and bioavailability of products. Historical Background Drug legislation in India. polymerization and their influence on formulation and stability of products. S. dissolution and partitioning effects and their influence on formulation. Blood Products and Plasma Substitutes Classification of blood products. 2. Preformulation studies i) Study of physical properties of drugs like physical form. Dandiya. Drug substance . Drug Laws (A detailed study : Case study (actual/simulated) inclusive of recent amendments) i) Prevention of cruelty of animals act. 4. Jain: Pharmaceutical Jurisprudence 2. dried human plasma. Rules 1976. human fibrin foam. xiv) AICTE Act. Khar: Hospital & Clinical Pharmacy. K. viii) Factory Act. plasma substitute. human normal immunoglobulin. Paper BPH 18 PHARMACEUTICS -VII FORENSIC PHARMACY AND ETHICS (THEORY) Total Teaching Hours: 50 1. v) Drugs and Magic Remedies (Objectionable Advertisements) Act 1954. decarboxylation. iv) Narcotic Drugs and Psychotropic Substances Act. Allwood and Fell: Hospital Pharmacy. Validation Design.E Hassan: Hospital Pharmacy. polymorphism. R. Khanna: Pharmaceutical Jurisprudence. xii) The Insecticide Act. Books Recommended 1. Xiii) Indian Patents Act as applicable to drugs and pharmaceuticals.K. solubility. ix) Delhi shops and Establishment Act. 3. oxidation. W. 3. x) Medical termination of pregnancy Act. 6. xi) The Drug (price control) order. Khar and N. 5. ii) Pharmacy Act 1948. salt formation. ideal requirements and large scale preparation of dextran. Heifindal et al: Clinical Pharmacy & Therapeutics. concentrated human RBCs. 1987. Gumbani: Pharmacist year Book CBS Publisher. development and process validation methods for pharmaceutical operations involved in the production of pharmaceutical products with special reference to tablets. N.excipient interaction study. iii) Study of pro-drugs in solving problems related to stability. bioavailability and elegancy of formulations. human fibrinogen. P. 2. Tata Publishers. and Rules there under. collection. vii) Poison Act. . Rules 1945. Pratibha Nand and R.2. Code of Ethics for Pharmacists.K. P. human thrombin. Paper BPH 19 PHARMACEUTICS -VIII PHARMACEUTICAL FORMULATION AND COSMETOLOGY (THEORY) Total Teaching Hours: 50 1.C. iii) Drugs and cosmetic Act 1940. processing and storage of whole human blood. racemization. ii) Study of chemical properties like hydrolytic degradation. Aggarwal and R. vi) Medicinal and Toilet Preparations (Excise Duties) Act 1955.
6. medical and pharmaceutical applications of radiopharmaceuticals. Vargheese Publishing House.F. 5.Williams and W. 3. 6. L. Martin: Physical Pharmacy.Mittal. hair creams. . J.. PRACTICALS Total Hours 75 Preparation and quality control tests for: i) Cold cream ii) Vanishing cream iii) Cleansing lotion and cream iv) Moisturizing cream v) Hair creams vi) Hair setting lotions vii) Shampoos viii) Hair colorants ix) Shaving creams x) Tooth powders xi) Tooth pastes xii) After shave lotions xiii) Other cosmetics xiv) Stability study of some formulations. 1991. S. Harry's Cosmetology 13.Z.Y. Skin Care Products Introduction to anatomy and physiology of skin. Second Edition. 4. 7. shampoos.A. Mumbai.A.Poucher: Perfumes. antiperspirants and deodorants. Hair Care Products Introduction to hair structure. Textbook of Pharmaceutical formulation. Khar and Alka Ahuja: Text book of Dosage Form Design. F. Cosmetics and Soaps Vol. tooth powder and tooth paste. Reinhold Pub. Books Recommended 1. Lea and Febiger. 2. W. G. 9. colors. Aulton: Pharmaceutics. Kaing: The Theory and practice of Industrial Pharmacy. formulation of skin cleansers and moisturizers . Science of Dosage Form Design. 2004. radiological safety. University Printing House. perfumes. Rhodes: Modern Pharmaceutics. Mumbai. 1990. Dental Products: Dentifrices. 1988. H. hair conditioners. Vargheese Publishing House. Marcel Dekker. 7. E. A. Raw materials used for Cosmetic preparations Surfactants. 5. Philadelphia. Roop K. Volume 40. Wells and H. I. M.Schmitt: Chemistry and Technology of the cosmetics and Toileteries Industry. Radio Pharmaceuticals Production of radiopharmaceuticals. radiation hazards. 12.M.4. Lieberman and J. 14. Remington's Pharmaceutical Sciences. A.Lubove: Cosmetics and the Skin.Rawlins: Bentley’s Textbook of Pharmaceutics. hair setting lotions. 11. L. 1973. 1987. L. Banker and C. preservatives.H. Javed Ali. New York. II and III Chapman and Hall London. 10. Lachman. after shave preparations. Design and Bioavailability. Swarbrick: Current concepts in the pharmaceutical Sciences: Dosage form. 8. Birla Publications. 8. sun screen products. T. Color Cosmetics Lipsticks and nail lacquers 9. In Drug Design. humectants. 10. hair bleaches and dyes. Personal Hygiene Products Shaving soaps and creams. Inc. D. B. E. Benet: Biopharmaceutics as the basis for the design of drug products. herbal materials. Oxford. New York.
10. potentiometric acid-base titrations. Benjamin. polarimeter. 9. PRACTICAL Total Hours: 100 Experiments based on surface tension. polarization types of molecule analyzed. M. acid base catalysis. Ionisation and ionic equilibria Arrhenius theory. hydrolysis of salts. 2. partition. Solutions Colligative properties (Lowering of vapour pressure and Raoult's Law. . solvent. Exercises involving polarimetry. potentials of galvanic cells. applications in pharmacy.J. degree of ionisation and Ostwald dilution law.R. Books Recommended 1. J. Printeil. buffer solutions and preparation of pharmaceutical buffer solution. kinetics. Conductometric analysis Definitions of units in conductometric titrations.. approximate calculation of buffer capacity excluding the derivation of Vanslykes equation of buffer capacity. Chromatography Fundamental principles of chromatography. 3. viz. 4. temperature on optical rotation. effects of concentration.Paper BPH 20 PHARMACEUTICAL CHEMISTRY-V PHARMACEUTICAL ANALYSIS II PHYSICAL CHEMISTRY & PRINCIPLES OF INSTRUMENTAL ANALYSIS (THEORY) Total Teaching Hours:-50 1. poisoning and applications of catalysis. thin-layer chromatography. Longman. Wallwork: Physical Chemistry for Students of Pharmacy and Biology. solubility product. S. Atherden: Bentley and Driver’s-Textbook of Pharmaceutical Chemistry.S. theories of semipermeable membranes. measurement of osmotic pressure. Principles of turbidimetry. enthalpy. 7. paper. 2.C. Mce: Physical Chemistry. pharmaceutical applications of osmosis. London. E.J. adsorption. 6. spectrophotometric method. K. depression of freezing point and its determination). gas chromatographic and electrochemical methods. heat capacity. Catalysis: Homogeneous and heterogeneous catalysis. viscosity. 5. B. Thermodynamics First law of thermodynamics. oxidation-reduction titrations. Measurement of conductance. gas chromatography and electrophoresis. sample cells. work done in expansion of gases. Spectrofluorimetry Fluorescence. Delhi. DebyeHuckel theory. Laidler: Physical Chemistry with Biological Applications. solubility products. Potentiometric analysis Electrodes and reference electrodes. 5. light source.L. L. theories of catalysis. physical and chemical methods for water determination. Barrante: Physical Chemistry of Life Sciences. column. buffers in pharmaceutical and biological systems. electrolyte and non electrolytes. internal energy. A. elevation of boiling point and its experimental determination. 3. Karl Fischer. precipitation and complexometric formation. partition coefficient. wavelength. Distribution law and solvent extraction method. and critical solution temperature. osmosis and osmotic pressure. Aquametry Brief account of aquametry. Polarimetry Principles and applications. refractometry and pH-determination. Oxford University Press. applications and conductance in non-aqueous solution. 4. spectrofluorimetry and analytical factors. optical rotation. Instrumentation. 8. potentiometric pH determination.
ii) Drugs Affecting the Peripheral Nervous System Local anesthetics. iii) Drugs Affecting the Autonomic Nervous System Adrenergic agents. Phenobarbital. Meprobamate. The Athlone Press of the University of London. Merritt and J. Physostigmine. Diclofenac. Haloperidol. Diphenoxylate. Bethanechol. 8.6. Levo-Propoxyphene. Triamterene and Amiloride. Connors: A Textbook of Pharmaceutical Analysis. Oxazepam. Chlorthalidone.Willard. Ibuprofen. Ephedrine. iii) Drugs acting on autonomic nervous system: Epinephrine. antipsychotics. iv) Drugs acting on kidney: Acetazolamide. Macmiilan Press. Diphenhydramine hydrochloride. Promethazine and Meclizine. Phenylbutazone. Allopurinol. Tripelennamine. antiadrenergic agents. Amitryptiline. Lidocaine. Chlorphenesin. iv) Drugs Affecting the Kidney Diuretics. Perphenazine. Ethosuximide. Loperamide. Valproic acid. antiparkinson agents. histamine and antihistamines. cholinergic agents. Malathion. Isoproterenol. 3.Interscience. Chlorpheniramine. Clidinium Bromide. Paper BPH 21 PHARMACEUTICAL CHEMISTRY VI MEDICINAL CHEMISTRY-I (THEORY) Total Teaching Hours: 50 1. Thiopental sodium. Benztropine. Risperidone. Acetylcholine. H. Lorazepam. Samuel Glasstone and David Lewis: Elements of Physical Chemistry. Phenytoin. Imipramine.L. Diazepam. Fluoxetin and Meclobemide. Metaprolol. Methoxyfluorane. anticonvulsants. New York. The following topics shall be treated covering uses. anxiolytics. 9. 2. Clozapine. Diazepam. Physico-Chemical properties of drugs in relation to biological activity. Pheniramine. . New York. Van Nostrand Reinhold. PRACTICAL Total Hours:100 Synthesis of compounds of medicinal interest including synthesis involving two steps and synthesis of heterocyclic compounds. Naproxen. Beckett and J. Vol. Pyrilamine. Modern concepts of rational drug design: a brief introduction 4. Glutethimide. Naphazoline. Oxazepam.A. Spironolactone. metabolism. and Dantrolene Sodium. Chlorpromazine. Phentolamine. Indomethacin. Phenoxybenzamine. Molindine. The outline of the synthetic procedure of the following drugs will also be covered: i) CNS acting agents: Halothane. Mefenamic acid. antidepressants. Levallorphan. Chlorthiazide. Principles of medicinal chemistry including drug absorption. Staenlake: Practical Pharmaceutical Chemistry. Dichlorphenamide. Oxyphenbutazone. Benzocaine. Trimethadione. distribution and elimination. K. Dean: Instrumental Methods of Analysis. opiate analgesics. nonopiate analgesics. I and II. ii) Drugs acting on peripheral nervous system: Cocaine. London. Nimesulide. Ethacrynic acid. Pyridostigmine. L. nonsteroidal antiinflammatory agents. Methacholine.H. A. sedative-hypnotics. Chloral hydrate. Furosemide. 5. Propranolol. Aspirin. hallucinogens. Wiley . structure activity relationship including physico-chemical and steric aspects and mode of action: i) Drugs Affecting the Central Nervous System General anesthetics. Acetaminophen.A.H. Probenecid. Dicyclomine.B. anticholinergic and antispasmodic agents. Terbutaline. Norepinephrine. skeletal muscle relaxants. Buspirone. 7.
Preliminary studies along with synthesis of purine and pyrimidine bases. 2.and polysaccharides: glucose. Lippincott. saponification value. Books Recommended 1. cellulose. a -terpineol and citral. tertiary and quaternary structure of protein. pinene. Mitschier: Ale Organic Chemistry of Drug synthesis Vol. of India.O. starch. I. estimation of functional groups. nicotine. 7. 3. structure determination and synthesis of caffeine. menthone. secondary. Xanthine bases Introduction in relation to uric acid. isolation. structure elucidation and syntheses of some selected simple members. 4. Lea & Febiger.N. Chemistry of Nucleic acid. ephedrine. Ministry of Health. dextran and Chitin. carboxylic groups and acetyl group. reserpine. John Wiley and Sons. papaverine. Basic idea regarding primary. ester value and hydroxyl value. Study of the naturally occurring glycosides (excluding cardiac glycosides) Indican ruberythric acid. isolation and structure determination of some important terpenoids: Limonene. Paper BPH 22 PHARMACEUTICAL CHEMISTRY VII NATURAL PRODUCT CHEMISTRY (THEORY) Total Teaching Hours:-50 1. Carbohydrates An account of the chemistry of mono. Isolation of a few naturally occurring compounds such as caffeine. Study of the chemistry of lipids (fats. New Delhi. 6. R. II & III John Wiley and Sons. II. iodine value.E. 2. Govt. from tea leaves.. 2. 5. salicin.Bansal: Heterocyclic Chemistry. Pharmacopoeia of India. menthol. Wolf:Burger's Medicinal Chemistry. morphine. 5.Finar: Organic Chemistry Vol. determination of acid value. Wilson & Gisvold's: Textbook of Organic Medicinal and Pharmaceutical Chemistry.-I and II.Books Recommended 1. Doerge. The English Language Book Society.L. New Delhi.A. Vol-I. Delhi. New York. 3.Publishers. W. quinine.F. sinigrin and arbutin. Proteins and amino acids Classification. general nature of proteins. 6. PRACTICAL Total Hours: 100 1. Alkaloids Isolation. 4. camphor. Joul Smith: Heterocyclic Chemistry. 'The English Language Book Society. M. Analysis of fixed oils:. 2. belonging to different groups. fructose. Philadelphia. general methods of determination of structure. atropine. Ashutosh Kar: Medicinal Chemistry. S. End group analysis. sucrose. R. Wiley Eastern. 1. Estimation of following organic groups: hydroxyl (alcoholic and phenolic). amygdalin. Terpenoids Classification. Wiley Eastern. di. lactose. amino. D.Lednicer and L. 3. New York. oils and waxes). ELBS. cinchonine. 7. 3. S. cineole. 4. classification of proteins.Foye: Principles of Medicinal Chemistry.Finar:Organic Chemistry Vol. General methods of isolation of natural products. 8. glycogen.L. maltose. phospholipids. London. cocaine. I.K. London. general methods of preparation and properties of amino acids. . Ltd. theophylline and theobromine.G.Pandeya: A Textbook of Medicinal chemistry. London. Varanasi.
cotton seed oil. senna. ginseng. adulterants and uses of: Areca nut. Rauwolfia. chemical constituents. Cinchona. 2. Pectin. strophanthus. oleander. 2. Caraway. Vinca. Books Recommended: 1. black catechu. Tea. cascara. chemical constituents. Citronella. Ajowan. chemical constituents. wild cherry. 4. Guar gum. Tannins Biological sources. Tragacanth. Coffee. sesame oil. guggul lipids. Cumin. Belladonna. Clove. senega. Stramonium. PRACTICAL Total Hours: 75 1. 3.Paper BPH 23 PHARMACOGNOSY III PHARMACOGNOSY & PHYTOCHEMISTRY (THEORY) Total Teaching Hours:-50 1. Tolu balsam. shark liver oil. Cinnamon. Guargum.Text Book of Pharmacognosy. Podophyllum. Resinous drugs Classification. Ipecac. adulterants and uses of: Starches. adulterants and uses of: Digitalis. cinchona and opium alkaloids. Ergot. Coca. 2. Microscopy of: Datura. Chenopodium. Pune. Nutgalls. 5. Orange peel. Terminalia arjuna. Clove. CBS. Biological sources. Cinchona. Clove. quassia. Biological sources. Nutmeg. Asafoetida. Duboisia. Agar. Myrrh. Ali. 4. Agar. Sandal wood. rhubarb. Lipids Biological sources. kokum bitter. P. Biosynthesis of Cardiac and Anthraquinone glycoside. Hyoscymus. chemical test and uses of: pale catechu.K. Biosynthesis of tropane. Opium. Colophony. Lobelia. (2 Weeks) 5. Sodium alginate. identification test. Cassia. Jalap. Ipecac. neem oil. Solanum xanthocarpum. Bael. New Delhi. Cardamom. Nux vomica. Gaultheria. Gokhle: Pharmacognosy. 3. Aconite. Physostigma. Quassia. chemical constituents. Kokate. adulterants and uses of: Black pepper.K. chalmooogra oil. Pharmacognosy tour for field collection of medicinal and aromatic plants. withania. Acacia gum. 7. Sterculia. formation and chemical nature. Plantago. Ephedra. ruta. olive oil. Black catechu. chemical constituents. Cinchona. Thevatia. Eucalyptus. Fennel. Benzoin. rice bran oil. Chemical tests of: Starches. .Mukherjee: Quality Control of Herbal Drugs . P. quillaia. Thevetia. Palmarosa. Star anise. Lemon peel. Tolu balsam. Asafoetida. Glycosides Nature and classification. Colchicum. glycyrrhiza. Veratrum. Alkaloids Biological sources. thevetia. Mohd. Tannic acid. Purohit and S. Nux vomica. Cinnamon. chemical constituents. Plantago. Dill. Ipecac. Tragacanth. Nux vomica. chemical constituents. Anise. Rauwolfia. Ginger. Pale catechu. Fennel. Colocynth. Peru balsam. Aconite. Caraway. Lemon grass.B. Peru balsam. Preparation of herbarium sheets and monograph on one of the collected plant during tour. Terminalia chebula. Mentha. Acacia gum.P. 3. Vasaca. Turpentine. adulterants & uses of: Arachis oil. Volatile oils Biological sources. Aloe. Sesame oil. Honey. Nirali Prakshan. Carbohydrates Biological sources. Turmeric. gentian. Colchicum. Cinnamon. Kurchi. 6. adulterants and uses of: Benzoin. Cotton seed oil. squill. Coriander. Pilocarpus. aloe. Colophony. Terminalia belerica. Ephedra. dioscorea. Sterculia. cod liver oil. Identification of organised drugs studied in theory on the basis of morphological and sensory characters. Cannabis. Spearmint. C. castor oil. Capsicum. Bitter almond.
Jammu. Study of anticonvulsant activity. vii) Nitric oxide. Lavoisier Publishing.Harborne: Phytochemical Methods. Handa and M. S. Drugs Acting on Respiratory System i) Expectorants. iv) Plasma expanders. ii) Antidiarrhoeal drugs. Determination of analgesic activity (codeine/aspirin). 4. Dissociative and neurolept. 4. 5. anti-inflammatory and anti-pyretic agents.Kaul: Supplement to Cultivation and utilization of Aromatic Plants. vitamin B12 and Folic acid). 2.M. Varghese Co. iii) Antihypertensive drugs. Diuretics 5. iii) Antacids and treatment of peptic ulcers.4. vi) Psychopharmacological agent. iii) Haematinics (iron. V. Study of phenobarbitone induced hypnosis (Demonstration). iii) Drugs used in common cold. iv) Emetics and antiemetics. viii) Non-steroidal analgesics. opiod pois oning and treatment. iv) Alcohol. PRACTICAL Total Hours: 100 1. 3. Drugs Acting on Central Nervous System i) Synaptic transmission in the CNS. ii) Anticoagulants.S.anaesthesia.S. ix) Narcotic analgesics. 6. RRL. v) Prokinetic agents. 2. ii) General anaesthetics. 3. 6. Drugs Acting on the Blood and Blood Forming Agents i) Coagulants. iv) Coronary vasodilators and drugs used in angina. Handa and M. Jammu. L.B. v) Antiepileptics. S.R. Stages of chloroform and ether anesthesia with and without premedication. ii) Antiarrhythmic drugs.E. RRL. London. Jean Brunet: Pharmacognosy and Phytochemistry. K. 8.Tylor..B. xi) Local anaesthetics. Drugs Acting on Cardiovascular System i) Cardiac glycosides and positive ionotropic agents. Medicinal Plants.K Kaul: Supplement to Cultivation and utilization of Medicinal Plants. vii) Antiparkinsonian drugs. vi) Fibrinolytic agents. ii) Antitussive bronchodilators. v) Hypolipidemic drugs. iii) Hypnotics and sedatives.Robbers: Pharmacognosy. Paper BPH 24 PHARMACOLOGY-II (THEORY) Total Teaching Hours: 50 1. 7. Bombay. . drugs used in gout. Brady and S.K. J. France. x) CNS stimulants and Nootropic agents. Chapman and Halls. Drugs Acting on Gastrointestinal System i) Purgatives.
iii) HMP pathway.Tripathi: Essentials of Medical Pharmacology.Turner and Peter Hebbom: Screening methods in Pharmacology. 7. K.K. ii) Oxidation of fatty acids.K. R.Satoskar and S. ii) General mechanisms of enzyme action.P.E. Alan S.5. revised.Rang and M.K.D. K. lan Kitchen: Text book of invitro Pharmacology 6.S.Craig and R. 3. Seminars on the drugs studied in theory. Robert A.Rall. ii) Oxidative phosphorylation.Kamat: Selected topics in Experimental Pharmacology 7. iii) Biosynthesis of fatty acids. F. ii) Aerobic metabolism (Kreb's cycle). 5. Pharmacological experiments on isolated preparations by Edinburgh University Pharmacology Staff.Ghosh: Fundamentals of experimental pharmacology 5. Metabolism of Lipids i) Fatty acid metabolism. M. Paper BPH 25 BIOCHEMISTRY (THEORY) Total Teaching Hours: 50 1. Theodore W.Stitzel: Modem Pharmacology 2. Identification of unknown drugs using rat ileum. S. Books Recommended: Theory 1. D.Sheth. 3.R.Dale: Pharmacology. K. Usha G. . ii) Infiltration anesthesia using guinea pigs.Nies and Palmer Taylor: Goodman Gilman's : The Pharmacological Basis of Therapeutics by Alfred Goodman Gilman. 7. 6. Study of local anesthetic activity. v) Hormonal influence on the mobilisation of fat in adipose tissue. Vol. i) Surface anesthesia activity on rabbits. 6. Pillai: Experimental Pharmacology.D. vii) Gluconeogenesis. 8. H. C.M.Bennett: Clinical Pharmacology.Kulkarni: Handbook of experimental Pharmacology 4. U.Bhandarkar: Pharmacology and Pharmacotherapeutics. v) Application of metabolic antagonism. iii) Factors affecting the velocity of enzyme catalysed reaction. Biological Oxidations i) Oxidation-reduction chains in nature. Delhi. Enzymes i) Classification of enzymes.N. vi) Glycogenolysis. CBS.S. iv) Regulation of blood glucose concentration.R. iv) Synthesis and degradation of triglycerides. v) Glycogenesis. 4.Dadkar. 2.N. 2. N. 1968. Barar: Essentials of Pharmacotherapeuties. iv) Activators and inactivators of enzymatic reactions. James Crossland: Lewis's Pharmacology.Laurence and P. 4.K. Metabolism of Carbohydrate i) Anaerobic metabolism of Glucose. Practical 1.1 edited 3.
Albert L.Rodwell: Harper's Review of Biochemistry. iv) RNA and transcription.Plummer: An Introduction to Practical Biochemis try. Estimation of protein in Serum. H. 6. Fat determination in milk. Lubert Stryer: Biochemistry. Victor. 7. Harold Varley: Practical Clinical Biochemistry. Peter A. v) Gene-protein relationship. Metabolism of Inorganic Elements Calcium. 5. 7. Estimation of Chloride in Serum and Urine. 8. 9. ii) DNA genetic role. Books Recommended Theory 1. 3. Determination of Serum bilirubin. 6. W. Cloning v ectors . Basic Principles of Molecular Biology Gene cloning: Restriction endonuclease. 8. . Protein Synthesis i) Transmission and expression of genetic information. 4. Estimation of Uric acid in Serum and Urine.James: Biochemistry for Medical Students. 9. David T. iii) DNA Structure and replication. Determination of acid and alkaline phosphate. Determination of SGOT and SGPT. 6. Restriction sites. 13.vi) Ketosis. Electrophoretic separation of Serum proteins. Estimation of Liver glycogen. 3. Karlson P: Introduction to Modem Biochemistry. 10. Magnesium. Abraham Mazur and Benjamin Harrow: Textbook of Biochemistry. Phosphorous. W. 11. John W. McGilvery and Gerald Goldstein: Biochemistry .W. Estimation of RNA and DNA. ii) Metabolism of tyrosine and Tryptophan. Estimation of glucose in blood.Suttle: Introduction to Biochemistry. Determination of Creatinine and Creatine in blood and Urine. 8.Malhotra: Practical Biochemistry for Students. Bray and Sybil P. 5. DNA library.A functional approach. 4.G. Metabolism of Proteins i) Amino acid degradation and urea cycle. Antibiotic marker gene.Lehninger: Principles of Biochemistry. Application of DNA recombinant technology. PRACTICAL Total Hours: 50 1.Mayes. 5. Practical 1. 7. Metabolism of Nucleic Acids Metabolism of purines and pyrimdines. 2. 2. 2. 3. Trace elements. Determination of blood Cholesterol. R. vi) Control of Protein Synthesis. 12.Martin. Varun K.
B-PHARM IV TH YEAR .
selection. application of transgenic animals. Motivation Objectives. Barriers to communication.Paper BPH 26 PHARMACEUTICAL BIOTECHNOLOGY (THEORY) Total Teaching Hours: 50 1. R.M. grievance redressal machinery. Degraland. media of communication. Structure of immunoglobulins. Personnel Management and Industrial Relations Objectives and functions of personnel department. Animal Biotechnology i) Animal cell and tissue culture. iv) Applications of biopolymers.B. Types of motivation. Theories of motivation: McGregor's Theory X and Y. iii) Biopolymers and its types. Goding: Monoclonal Antibodies. Glick and J.C. rules of motivation. Pasternak: Molecular Biotechnology: Principles and Applications of Recombinant DNA: (1998) ASM Press Washington D. Agrobacterium mediated.. EmployeeCentered approach. remedies. Industrial relations: problems of labor management relations. types of communication. iii) Recombinant DNA technology. S. somatic hybridization. protoplast fusion. need for grievance procedure. ii) Basic principles of genetic engineering. . (2001).oral vs. (1986). Walker and E. employment and development of personnel. 3. industrial dispute act. causes of industrial disputes. Gingold: Molecular Biology and Biotechnology by Royal Society of Chemistry. (1973) CRC Press. vaccine development and immunization. Vroom's expectancy theory. iv) Use of microbes in industry. direct gene transfer methods. Communication failure. Herzberg's time factor theory. 5. 2. motivation steps. Primrose: Molecular Biotechnology (Second Edition) (1999) Blackwell Scientific Publication. 6. nature of communication. 4.applications of protoplast fusion. ii) Methods of gene transfer in plants. RA Goldshy et. Financial and non-financial motivators. trade union grievance and grievance handling procedure. Behavioral theory.W. Achieving effective communication. : Kuky Immunology. McClelland's need for achievement theory. ii) Brief introduction to Protein Engineering. 2. microbial transformation. Zaborsky: Immobilized Enzymes. J. Hybridoma and monoclonal antibodies. Communication Importance. Ohio. transfection methods.Endress: Plant Cell Biotechnology (1994) Springer-Verlag Berlin Heidelberg. Industrial and Microbial Biotechnology i) Enzyme Biotechnology. iii) Immunotoxin and Drug designing. J. causes of grievances. ii) Immunotechnology.B. media. iii) Applications of transgenic plants. Application of immobilized enzymes. iv) Application of genetic engineering in medicine.J.R. Paper BPH 27 PHARMACEUTICS IX PHARMACEUTICAL MANAGEMENT Total Teaching Hours: 50 1. B. Books Recommended 1. al. Isolating and culturing of microorganism. Plant Biotechnology i) Protoplast isolation. use of marker and reporter genes. 2. 3. bioreactors. written.Methods of enzyme immobilization. 7. 4. 3. Genetic Engineering i) Brief introduction to biotechnology with reference to pharmaceutical sciences.
equipment. 1974. Stauble The Dryden Press. by S. Developing Management Skills. Principles of Marketing. inventory management. R. Production and Maintenance Management A brief exposure of various functions and objectives of production management. Davar. The Wheel of Retailing. production organization. statistical demand analysis. Responsibilities.K. Objectives of maintenance management. factors affecting drug absorption-physicochemical.P. physiological and pharmaceutical. procurement cycle and its methods. of Advertising Research. Books Recommended 1. depot. by D. salesmanship. July 1960. 3. Management: Tasks. methods and types of purchasingcentralised and decentralised purchasing. various activities of production management. theories of selling process.S. 10.S. frequency distribution). Practices. steps to develop a formulary.Hollander. trends in location of a plant. Types of stores. Advertising/ Sales Response functions. safety stock. organisation and responsibilities of purchasing department. inventory carrying costs. Personnel management and Industrial Relations. of Marketing. Introduction to biopharmaceutics.and R. Materials management. designing training programs to improve pharmaceutical logistics. layout of injectable unit or sterile area. Drug Absorption Various mechanisms. Drucker. 523. Drug Supply Planning and management. 72-73. location and layout of a store. probability distributions. Tenth Edition. 11. Marketing Management by Philips Kottler. layout of stores in an industry. 14. 2.4. by Borbon. 7. pp7-15. Purchasing and Store Keeping. 5. problems and development. by Philips Kottler. (charts. 6.K. New York: Harper and Row. Rajput. J. Stanley C. planning for drug supply. . Srivastava and S. Quantitative techniques for managerial decision making. market and sale forecasting. Rajput. Cameron . Amber G. 1995. concepts and its role in formulation development and clinical setting. Peter F. value analysis. historical development of the subject. Pharmaceutical Marketing by Smith. Whetton and K. by Mamoria. tableting department and area requirement for each department. Printice Hall of India Pvt. predicting drug requirements. 7. J. by R. Sharma. classification and codification of stores. 5. systems. April 1975. pp 37-42. Managing Drug Supply: management sciences for health. by U. 2. lead time. fundamental principles. Pharmaceutical Marketing Goals. New York: Harper Collins. 8. by Gopalkrisnan. Ltd. Establishment of a pharmaceutical factory. 12. Establishment of a pharmaceutical factory Choice of site. supply process and its pitfalls. Marketing Strategy: A Global Perspective by Vernon R. channels of distribution advertising. plant facilities. reliability engineering.C. productivity and wastivity. types of sales organizations. 9. ABC analysis. Rao and Peter B. solutions to problems relating to EOQ. Paper BPH 28 PHARMACEUTICS -X BIOPHARMACEUTICS AND PHARMACOKINETICS (THEORY) Total Teaching Hours: 50 A.K. Miller. market test method. 6. 9. qualification of a salesman. D. Gupta. economic ordering quantity. 8. presentation and analysis of statistical data. preventive maintenance and its benefits. surplus and scrap management. planning models.A. 13. definition. company market. obsolete. Aganil. 15. 4. Materials management Materials handling. Biopharmaceutics 1. Purchasing and Store Keeping Objectives.R. Personnel management.
Pergman. Detection of non-linearity (saturation mechanism). 7.v. Barr: In Robinson. A. Compartment models . 5. TextBook of Biopharmaceutics and Pharmacokinetics. IM and P. Extraction ratio. 10. R. 7. R. Rothman: The assembly of cell membranes Sci.v. (eds) Controlled Drug Delivery. One compartment open model. and J. Dosage adjustment in patients with and without renal failure. 5. Drug disposition Distribution in blood. Evaluation of antacid products. R. NewYork. NewYork Macel Dekker. (1987). Swarbrick: Current concepts in Pharmaceutical sciences and Biopharmaceutics 9.F.R.G. clearance ratio. drug administration. 8. Shargel and Yu: Text Book of Biopharmaceutics and Pharmacokinetics (Prentice Hall). Controlled drug bioavailability published by Wiley interscience. 12. V.concepts and their importance in the study of pharmacokinetics. J. 14. plasma -protein binding. 11. 8. Practice numericals based on the portions covered under theory syllabus. 14. J. 3. biliary excretion. Wagner: Text Book of Biopharmaceutics and Pharmacokinetics. pharmacokinetics of single and multiple dose administration as applied to intravenous (rapid) and oral administration. Blanchard and Brodie: Principles and Perspective in drug bioavailability. 11. Rowland and Tozer: Textbook of clinical Pharmacokinetics 8. Remington’s Pharmaceutical Sciences. Pharmacokinetics 5. PRACTICALS Total Hours 100 3.L. Effect of protein binding by egg albumin. 4. Robinson: In Oral sustained release formulations. Establishment of standard curve of a drug substance. Concepts. 6. 1987. Amidon: J. intravenous transformation. . by acid neutralizing capacity and Rosset-Rice test methods. Javed Ali. and Biopharm. Khar and Alka Ahuja.K. review of regulatory requirements for conducting bioequivalence study. Two compartment open model. application of drug-protein binding. determination and evaluation of bioavailability of drug administered by IV.E. 2001.3.E. B.l. Determination of pharmacokinetic parameters from plasma and urine data after i. 9. Drug release from capsules. Release of drug from suppository base.P. J.L. Influence of vehicle on drug availability from topical dosage forms in-vitro. A. Tamai: I Pharm. extra hepatic circulation. determination of renal clearance. injection and oral administration.H. 4. 2. 10.O. 6. W.H. Determination of bioavailability of marketed formulations by plasma concentration method. Determination of bi oavailability and bioequivalence: Measures of bioequivalence study and single dose bioequivalence study and relevant statistics. Pharmacok. dialysis method. 1988 chap 6. Li and J. Comparative in-vitro release rate studies of marketed formulations. Skelly. Design and Evaluation. 13. effect of diluents etc. 4. Oberle. Determination of pharmacokinetic parameters. J. 10. Notari: Biopharmaceutics and Pharmacokinetics. Fundamentals and applications 2nd eds.H. Introduction to pharmacokinetics. Am. Lodish. 6. Non-Linear Pharmacokinetics with special reference to one compartment model after i. Carrier mediated intestinal transport of drugs 13(7) 963-977 (1966). definition and explanation of terminologies used. mechanism of renal clearance. Birla Publication. importance in bioavailability and clinical practice. Percent absorbed time plot and absorption rates based on one compartment model. 7. Determination of bioavailability of marketed formulations by urinary excretion method. Disintegration and Dissolution of peroral tablets. 15: 529-544. V. 12.. 9. 1979. Michaeles Menton equation. 13. G.Rubinstein. Roop K. 11. Tsuji. Clearance concept. 240:48-63. Lee. hepatic clearance. H. Books Recommended 1. Res.
Introduction to implantable and transdermal therapeutic system. c. and ophthalmic dosage forms. 9. Quality control of tablets. materials used. 6. Preparation of sustained release dosage forms employing various techniques. preparation of components for compression. 7. types of systems. Dry granulation (Slugging). 42 :1651 (1977). Good manufacturing practices for pharmaceuticals Status and applicability of regulation. film defects. Reg. capsule production. Quality control of capsules. Ind. 8. oral. packaging of solid. Measurement of tablet punch forces Transmission of forces through a powder. P. Packaging technology Types of containers. 10. film coating. parenterals. quality control and testing. Strip packing of tablets. equipments. operation of an aerosol package. Wet granulation (Aqueous). Soft gelatin capsules: Manufacture. manufacturing. design and fabrication of oral controlled release drug delivery system. PRACTICALS Total Hours 100 1. Coating of tablets . effect of pressure on the relative volume. Factors affecting the strength of tablets. nasal and topical aerosols. processing. equipment employed. closures. Preparation of an aerosol dosage form and its evaluation. 5. current good manufacturing practices in manufacturing. 1185-1225 (1983). mechanism and types of flow. 5. Tablet coating-Sugar coating. Wet granulation (non-aqueous). mixing mechanism. 16. 6. Gardner: Bioequivalence requirements and in-vivo bioavailability procedures Fed. Capsules Hard gelatin capsules: Formulation of shell and contents. filling operation and equipment employed. 8. 3. Filling and sealing of hard capsules. b.G. Welling: Pharmacokinetic considerations of controlled release drug products.sugar coating and film coating. . 4. additives and components. 2. Solids mixing. 4. Mixing Fluid mixing. Preparation and evaluation of microcapsules by employing various techniques. 3. Drug Dev. Controlled drug delivery system Introduction. 2. 9. production and process controls. stability aspects of packaging. processing and quality control. . Future developments. Microencapsulation Importance and application. unit dose packaging. Paper BPH 29 PHARMACEUTICS -XI PHARMACEUTICAL TECHNOLOGY (THEORY) Total Teaching Hours: 50 1. formulation. adhesion and cohesion of particles strength of granules and tablets. S. evaluation. terminology. forms of compressed tablets. inhalation. Any other experiments illustrative of the theory of syllabus. Preparation of tablets by the following techniques: a.15. 7.Pharmaceutical aerosols Components. 9. drug targeting. air suspension coating. strip packaging materials. Pharm. packaging and holding of drugs. Distribution of forces within the powder mass. Tablets Production of tablets. ISO 9000 certification. equipment. techniques.
2 and 3. 2001. S. H. Banker and C. Mass spectrometry Basic principles. High performance liquid chromatography.Books Recommended rd 1. and J. Marcel Dekker. N. mass spectra of some simple molecules. 1999. Jain: Advances in controlled and novel drug delivery system. Marcel Dekker. 1991. Kydonieus: Treatise on controlled drug delivery. instrumentation.. L. nd 3.T. Instrumentation. 2 Edition.. 2nd Edition. 11. Boylan: Encyclopedia of pharmaceutical Technology. ion-exchange equilibria. E. 6. A. Liberman. 6th Edition. spin spin coupling.Lachman. 12. Paper BPH 30 PHARMACEUTICAL CHEMISTRY-Vlll PHARMACEUTICAL ANALYSIS III (THEORY) Total Teaching Hours:-50 1. Inc. 7. and J. instruments and applications. Bruck: Controlled drug delivery. C. 13. Inc. equipment. 18th Edition. 1987. Inc. P. 18. 14. structure elucidation of simple organic compounds and qualitative analysis of drugs 4. Krowezynski: Extended release dosage forms. Swarbrick. and analytical applications. 4. Boca Raton. 9. 6. type of exchangers. Brody and K. M. Advanced chromatographic techniques Theory of ion exchange. Marcel Dekker.. Vol. 1988. D. 15.. NMR instrumentation. Vol. Mack Publishing Company. L. 7. 1989. CRC press. chemical shifts. GasTLC chromatography. molecular weight. 1990. 1986. Liberman. 2. Va ndana Publications. “Controlled drug delivery” (available at NC State University’s web sites http://www5. CBS Publishers and Distributors. types of ion. H.who. A. determination of molecular formula. Super critical fluid chromatography. Flame photometry Theory of emission spectra. Vol 1 -18. 2nd Edition. Nuclear Magnetic Resonance An introduction to the theory of NMR. J. 1997. 10. G. fragmentation. 1990. Schwartz: Pharmaceutical dosage forms: Tablets.S.edu) 17.Lachman: Theory and practices of Industrial Pharmacy. Aulton: Pharmaceutics: The science of dosage form design.ncsu. Vol. 14 5.bae. B. John Wiley and Sons Inc. qualitative and quantitative analysis. 1988. Cooper and Gunn’s Tutorial Pharmacy. L. Visible and ultraviolet absorption spectrophotometry Principles of visual and UV absorption spectrophotometry. 1987. qualitative and quantitative analysis. Kanig: Theory and practices of Industrial Pharmacy. 2nd Edition.int) 16. Robinson and Lee: Controlled drug delivery: Fundamentals and applications. A. A. S. 1. 2nd Edition Marcel Dekke r. ion-exchange separation. 8. 5. P. J. 2. L. 3.Rhodes: Modern Pharmaceutics. equipment. L. the mass spectra. Atomic absorption spectroscopy Theory of absorption of radiant energy by atoms. CBS Publishers and Distributors. L. and qualitative and quantitative applications with reference to flame photometry . applications in pharmaceutical analysis. Marsh: Encyclopedia of packaging technology. 1st Edition. K. HPTLC and instrumentation with reference to quantitative estimation of drugs and biopharmaceutical agents. Infrared spectrophotometry Origin of infrared spectra and regions. 2nd Edition.S Warbrick: Novel drug delivery systems. and J. I and II. ELBS publisher.. Remington’s Pharmaceutical Sciences. Sharma: How to practice GMPs. World Health Organization’s guidelines on good manufacturing practices and inspection (available at http://www. Marcel Dekker. 3 Edition. Lachman. 1995.
Willard.C. R. L. and chloramphenicol. stigmasterol. 1 and 11.H. vi) Antiarrhythmics.B. Bassier and J. New York. and Longman. D. H. Beckett and J.G. The ELBS. Jeffery and Medthan: Vogel's Textbook of Quantitative Inorganic Analysis including elementary instrumental analysis. isolation methods. Quantitative pharmaceutical chemistry. Dyer: Application of absorption spectroscopy of organic compounds. Books Recommended 1. tetracycline. 2. Vitamins (excluding the detailed study of constituents). New York.L.H. Vol I and II.8.Basset. v) Vasodilators. J. Polarography Introduction. ii) Antihyperlipidemics. Vol. estrogens and progestational agents (Oral Contraceptives). John R. Paper BPH 31 PHARMACEUTICAL CHEMISTRY IX MEDICINAL CHEMISTRY II (THEORY) Total Teaching Hours:-50 The following topics shall be treated covering uses. prednisolone. . G. Garrat: Quantitative analysis of Drugs. 3. New York.A. A. Van Nostrand Reinbold. 4. PRACTICALS Total Hours 100 1. 8. Drugs affecting blood and the cardiovascular system i) Anticoagulants. diosgenin. and dapsone. Denney. ii) Corticoids: Adrenocorticoids and glucocorticoids. stereochemistry. organic polarography.C. vitamin A. New York. Stenlake: Practical Pharmaceutical Chemistry. v) Steroids: Dexamethasone. 2. Ale Athlone press of the University of London. 6. 9. thiamine. iii) Prostaglandins.Merritt and J. 2. 5.Chatten: A Textbook of Pharmaceutical Chemistry. K. dropping mercury electrode. G. ii) Vitamins: Ascorbic acid. Dean: Instrumental Methods of Analysis. 7. 4.C. iv) Sulphonamides: Sulfanilamide. basic principles of polarographic instruments. iii) Cardiac glycosides. London. L.C. Analysis of as specified in Indian Pharmacopoeia. methods of analysis.H. Chapmann & Hall.A. R. Hormones i) Sex Ho rmones And Analogs : Androgens and anabolic agents. ciprofloxacin.John Wiley & Sons. experiments including amperometric titrations. classification. Mareel Dekker. iii) Barbiturates: Phenobarbitone. Connors: A Text Book of Pharmaceutical Analysis Wiley-Interscience. sulphadiazine. theoretical consideration. Different methods of analysis of following drugs related to functional group with particular reference to instrumental methods i) Antibiotics: Nalidixic acid. chemistry of cholesterol. beta-sitosterol and steroidal alkaloids. Morril: Spectroscopic identification of organic compounds. 3. ergosterol. Steroids Nomenclature. structure activity relationship including physicochemical and steric aspects and mode of action: 1. iv) Antihypertensive agents.M. Sliverstein. Experiments based on thin-layer and paper chromatography.
Norethnodrel. Phenoxybenzamine.C.E. Antimalarials Chloroquine. 12. Antiviral Amantadine. II. Sulphadiazine and Sulphamethoxazole. Cortisone. 6. 16. Idoxuridine and Ganciclovir. Antifungals Fluconazole. New York. Minoxidil. viii) Antimycobacterial agents. ELBS & Longman.O. Ethambutol. and Mechlorethamine. v) Antibacterial quinolones. 15.N. John Wiley and Sons. Antineoplastic Thiotepa. x) Antivirals.F. Varanasi. Phentolamine. Antitubercular Isoniazid. Antitrypanosomal Pentamidine. M. 11.. Menn and B. Steroids and Hormones Diosgenin.. Books Recommended 1.G. Chloramphenicol. Vogel’s: Text Book of Practical Organic Chemis try. The outline of the synthetic procedure of the following drugs will also be covered 6. New Delhi. 7. Aldosterone and Clomiphene. Propranolol. Tolnaftate and Clotrimazole. Primaquine. vi) Antibiotics. Organic Chemistry of Drug Synthesis. Proguanil. Doerge. S. PRACTICALS Total Hours 100 Two or three step synthesis of some compounds of medicinal interest.5. 9. Diethylstilbestrol. W. Philadelphia. Prednisolone. 2. Hydralozine. R. 13. Testosterone. J. S. Antiinfective and Antiinvasive Agents i) Antifungals. New York. and New York. xi) Antineoplastic agents. iv) Sulfonamides. 17. 8. Verapamil. 4. F. and Tocainide. Isothionate and Nifurtimox. & III. Antibiotics Doxycycline. Sulphanilamide. Lippincott Co. Progesterone. 3. Sodium Nitropruside. 7. Tinidazole and Diloxinide furoate. and Rifampicin. . 5. 14.Pandeya: A Textbook of medicinal chemistry. Pyrazinamide.A. Antiamoebics Metronidazole. Mitschlar. Thiabendazole and Niclosamide. ix) Anthelmintics. ii) Antiprotozoals. Betamethasone. A. Wiley Eastern. Foye: Principles of Medicinal Chemistry. Sulphonamides Sulphacetamide.-II. Cardiovascular Agents MethylDopa. ELBS & Longman. Enalapril. London.Publishers. 10. Saunders: Practical Organic Chemistry. Vol. Triamcinolone. iii) Antimalarials. Cyclophosphamide.Limited Publishers. Kar: Medicinal Chemistry. Atenolol. 8. Captopril. Lednicer and L. Carbenicillin and Cephalexin. vii) Antiamoebic. D. London and New York. Wolff: Burger's Medicinal Chemistry. Antihelmintic Mebendazole. Philadelphia. Carmustine. Lea & Febiger. Chlorambucil.G. Wilson & Gisvold's: Text Book of Organic Medicinal and Pharmaceutical Chemistry. John Willey and Sons. and Amodiaquine. Clonidine. Vol.
Turmeric) 8. Churna. Shikonin and Taxol. Phytopharmaceuticals Isolation. Rauwolfia. Preparation and evaluation of herbal drugs. Herbal formulations Principles involved in Ayurveda. Asoka (Saraca indica). steroids. microscopic. 6. terpenoids and resins.Paper BPH 32 PHARMACOGNOSY IV INDUSTRIAL PHARMACOGNOSY (THEORY) 1. 7. Skin care (Aloe. Quinine. 4. Solanine. paper and thin layer chromatographic techniques for the isolation of phytopharmaceuticals. Methods of adulteration Deterioration of herbal drugs by insect. Shankhpushpi ( Convolvulus microphylla). Kalmegh (Andrographis peniculata). 5. Piperine. 4. Tea. bioflavonoids. immobilisation of cells and enzymes. Tea). Guggul (Commiphora mukul). Isolation and TLC profile of volatile oils of: Eucalyptus. Brahmi ( Bacopa monnieri and Centella asiatica). characterisation and estimation of: Caffeine. Henna). Berberine. and Vinca. Gu ggul lipids and Katha industry in India. 9. Regulation pertaining to trade drugs. Diosgenin. Chirata (Swertia chirata). Gene transfer in plants. application of plant biotechnology. chromatographic techniques (TLC. Safoofs. Conditioners. (Amla. Traditional herbal drugs Common names. Eugenol. Isolation Techniques General methods used for the isolation and characterisation of alkaloids. Quality control and Standardization of herbal drugs Extractive values. physical. proteins. Herbal cosmetics Shampoos (soapnut). Saffron (Crocus sativa). Avaleha. Herbal formulation of Shampoos. Giloe (Tinospora cordifolia). Tannic acid. 2. Plant Biotechnology Tissue culture. Henna. active constituents and uses of: Punarnava (Boerhavia diffusa). sources. Isolation and TLC profile of Total alkaloids: Nu x vomica. Tailia. production of secondary metabolites. Ghutika. Hair darkeners (Amla. spectroscopic techniques and assay methods. Rutin. Menthol. Resins. Calcium sennosides. 3. Cinchona. Glycyrrhizin. Lipids. Salai (Boswellia serrata). preparation of Ayurvedic formulations like Aristas. Unani. 5. Artemisia (Artemisia annua). Intellectual Property Rights with special reference to phytoconstituents. Hibiscus. Biotransformation. Quality control and rational use of herbal drugs as per WHO guidelines. volatile oils. Ephedrine. Lehsun ( Allium sativum). Unani formulations like Majooms. WHO guidelines. . Application of column. Callus and suspension culture. ash values. Sennosides and Quinine. Andrographolides. chemical and biological methods. glycosides. Worldwide trade of crude drugs and volatile oils Plants based industries and research institutes. Pectin. Cumin and Lemon grass. Nutritional requirements. viz. Hesperidine. Evaluation of drugs by organoleptic. Valerian (Valerian officinalis). Tulsi (Ocimum sanctum). Asava. PRACTICALS Total Hours 100 1. Ghrita and Bhasms. Isolation of Starch. Sidha. Determination of heavy metals in herbal preparation and alcohol contents in Aristas and bhasams. Chinese and Homeopathic systems of medicines. HPTLC and HPLC) for determination of chromatographic markers. 6. Shilajit. 3. 2. lipids. Tannic acids. Morphology of traditional herbal drugs.
Books Recommended 1. Chemotherapy i) General principles of chemotherapy. 9. v) Sex hormones.7. C. 4.B. 2. Pharmacology of Endocrine System i) Pituitary hormones. iii) Insulin. iii) Antiprotozoal drugs. Evaluation of New Drugs i) Acute. British Pharmacopoeia. iv) Adrenocortical steroids and their antagonists. www. chloramphenical. Vol. GIucagon. Kokate. Vasopressin. Swelling factor. x) Chemotherapy of tuberculosis and leprosy. Quinolones and other antibiotics ( β-lactam antibiotic. 3. Wallis: Textbook of Pharmacognosy C. Chapman and Halls. Purohit and S.chemexil. contraceptives and drugs used in infertility. vii) Urinary antise.gov. 8. Jean Brunet: Pharmacognosy and Phytochemistry.M.K. L. vi) Drugs regulating calcium homoeostasis.antithyroid drugs. 13. xii) Immunomodulators. polypeptides).Wagner Zgainsky: Plant Drug Analysis. V. The Wealth of India. C. Indian Pharmacopoeia. 10. 3. ii) Teratogenicity and Carcinogenicity. 15.R. Harborne: Phytochemical Methods. tetracyclines. Oxytocin. Varghese Co. Brady and S. 1-10. oral hypoglycemics and glucagons. Gokhle: Pharmacognosy. ACTH.camag. Cineole. bisphosphonates. NISCAIR. S. 11. Verlag. Gonadotrophin. General mechanism of action of chemotherapeutics agents. London.E. Nirali Prakshan. Kapoor: Cultivation and Utilization of Medicinal & Aromatic Plants. Pune. xi) Chemotherapy of cancer. Bombay. 14. 2. 6. 5. subacute and chronic toxicity tests. T.B. Lavoisier Publishing.in 7. Medicinal Plants. Extractive values and foreign organic matters in herbal formulations. New Delhi.B.B.K. Balsamic acid. Publishers. RRL. 5. ii) Official methods of bioassay of: Insulin. Ayurvedic Pharmacopoeia.S. Stahl: Thin Layer Chromatography Springer. Quinine and Anthraquinone glycosides. 4. Vitamins . ix) Anti-helmintics. 12. v) Antimalarials. Ash value. ii) Sulfonamides. Estimation of Citral. Tylor. E. K.E.M. Delhi. vi) Antiamoebics. Paper BPH 33 PHARMACOLOGY-III (THEO RY) Total Hours: 50 1. Raw materials and Industrial Product. Heparin. France. macrolides. Determination of Moisture content.Atal and B. Carvone.ptics viii) Antifungal and antiviral drugs. Bioassays i) General principles and methods of Bioassays. ii) Thyroid . Robbers: Pharmacognosy. Berlin. www.com 8. iii) Clinical trials.P. P. Kirtikar and Basu: Indian Medicinal Plants. aminoglycosides. J. Jammu.B.
Barar: Essentials of Pharmacotherapeuties. Usha G.Bacharach: Evaluation of drug activities : Pharmacometrics.K. Edinburgh University Pharmacology Staff.K. U. K.L. Ghosh: Fundamentals of Experimental Pharmacology. Pillai.N. 7.R. 2.S. Books Recommended Theory 1.Bennett: Clinical Pharmacology. 1968.Stitzel: Modem Pharmacology. Vol.R. Practical 1. .Tripathi: Essentials of Medical Pharmacology. Pharmacopoeia of India.P. Sheth. Dadkar. 1. D.D.PRACTICALS Total Hours 100 Bio-assay of following by using appropriate isolated tissue preparation: Acetylcholine. F. lan Kitchen: Textbook of in vitro pharmacology. histamine.S. Theodore W. 7. 2. Alan Nies and Palmer Taylor. Goodman and Gilman's: The Pharmacological Basis of Therapeutics by Alfred Goodman Gilman. CBS. Oxytocin. James Crossland: Lewis's Pharmacology. Pharmacological Experiments on isolated p reparations. S. 6.K. Experimental Pharmacology. Kulkarni: Handbook of Experimental Pharmacology. Delhi.K. British Pharmacopoeia . Dale: Pharmacology.Rall. 4. C. 5. adrenaline.M. Pharmacology and Pharmacotherapeuties. 10. 6.Laurence and A.K.Satoskar and S. H. 3. 9.R. D. 3.Kamat: Selected topics in Experimental Pharmacology. R. Craig and R. 8. 5.Rhandarkar.E.N. N. M. 4. Laurence and P. K. Rang and M.D.