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beclomethasone synthetic glucocorticoid that readily penetrates the

airway mucosa, used for asthma

low potency dopamine receptor


thioridazine blocker

thioridazine side effects are retinal deposits, torsades, postural


hypotension, sedation, CNS depression

valproic acid causes neural tube defects

valproic acid used to treat all kinds of seizures, as well as bipolar


disorder

1
binds benzodiazepine receptors,
zolpidem antagonized by flumazenil

hypnotic drug that is not a


zolpidem benzodiazepine

amphetamines indirect sympathomimetic MOA

cocaine inhibits catecholamine reuptake, resulting in


cardiotox and hypertension

disulfiram inhibits aldehyde dehydrogenase, causing an


accumulation of acetaldehyde

2
benzodiazepine used as a date rape
flunitrazepam drug

lysergic acid diethylamide hallucinogenic, nausea, weakness

mescaline hallucinogenic, nausea, weakness

psilocybin hallucinogenic, nausea, weakness

lowers intraocular pressure in


marijuana glaucoma

3
methadone treatment of opiod withdrawal

nausea, chills, sweats, lacrimation, cramps,


opioid withdrawal syndrome rhinorrhea, yawning, piloerection, diarrhea, tremor

destroys dopaminergic neurons of


MPTP the nigrostriatal tract

morphine binds mu receptors

enkephalin binds delta receptors

4
dynorphins bind kappa receptors

constricted pupils, clammy skin, nausea, drowsiness,


opioid overdose resp depression

phencyclidine (pcp) nystagmus, hypertension, seizure

COX inhibitor which inhibits


acetaminophen prostaglandin synthesis

analgesic, antipyretic (but not


acetaminophen anti-inflammatory)

5
suicide inhibition of xanthine
allopurinol oxidase

allopurinol increases xanthine and hypoxanthine, which are less


likely to form crystals than uric acid

allopurinol slows production of uric acid, used to treat gout (and


cancer)

aspirin PGE inhibitor

aspirin predisposes to acute gastritis by inhibiting PGE in


the stomach

6
irreversible inhibitor of
aspirin cyclooxygenase

analgesic, antipyretic, antiplatelet,


aspirin anti-inflammatory

capsaicin impairs release of substance P

capsaicin used topically for RA

celecoxib COX-2 inhibitor

7
rofecoxib COX-2 inhibitor

celecoxib sulfa drug

rofecoxib sulfa drug

colchicine inhibits microtubule assembly, and therefore


leukocyte migration and phagocytosis

colchicine leukocyte inhibitor used to treat attacks of gouty


arthritis

8
cyclosporin binds to cyclophilins and inhibits the transcription of
cytokine genes

binds to the immunophilin


tacrolimus FK-binding protein

impairs T cell IL-2 production, used


cyclosporin in transplant patients

tacrolimus used in transplant patients

etanercept a fusion product of TNF-alpha receptor and Fc


portion of antibody

9
infliximab binds and inhibits TNF-alpha

used in RA and inflammatory bowel


etanercept disease

gold salts nephrotoxic

gold salts used in RA

decreases lysosomal and


gold salts macrophage function

10
similar to aspirin, lacks antiplatelet
ibuprofen effects

ibuprofen reversibly inhibits COX

indomethacin potent NSAID used to close a PDA

used to maintain a PDA in


PGE congenital heart disease

ketorolac parenteral NSAID

11
causes relaxation of the sphincter of
meperidine oddi

meperidine causes increased ICP

opiods causes biliary spasm

sumatriptan binds the serotonin 1D receptor

causes vasoconstriction of cerebral


sumatriptan vasculature

12
used for acute migraine and cluster
sumatriptan headaches

used to treat SLE, multiple


thalidomide myeloma, and leprosy

thalidomide suppresses production of TNF-alpha

potent
thalidomide immunosuppressant

statins may cause elevated liver enzymes

13
statins may cause myositis

may cause increased CK from


statins skeletal muscle

reserpine enters the CNS and may cause suicidal depression


and parkinsonian symptoms

antihypertensive agent that blocks the storage and


reserpine release of catecholamines and serotonin from
neurons

probucol decreases HDL as well as LDL

14
probucol prevents restenosis after angioplasty

probucol acts as an antioxidant

postural hypotension, headache,


nitroglycerin flushing

causes increase in cGMP in vascular


nitroglycerin smooth muscle

niacin directly reduces secretion of VLDLs

15
niacin increases HDL

niacin causes cutaneous flushing

vincristine M phase inhibitor

blocks microtubule polymerization


vincristine and spindle formation

adriamycin, bleomycin, vinblastine,


ABVD dacarbazine

16
mechlorethamine, oncovin,
MOPP procarbazine, prednisone

used for lymphomas, wilms tumor,


vincristine and choriocarinomas

heparin activates AT3

heparin inactivates thrombin

protamine sulfate reverses effects of heparin

17
binds to receptor tyrosine kinase
trastuzumab Erb-B2 (HER-2)

used for HER-2 positive breast


trastuzumab cancer

tamoxifen estrogen receptor partial antagonist

increases risk of endometrial


tamoxifen carcinoma

rituximab binds CD20 antigen on B cells

18
treatment of non-hodgkin
rituximab lymphoma

prednisone triggers apoptosis

treatment for leukemia, lymphoma,


prednisone RA, asthma

paclitaxel prevents mitotic spindle breakdown

interferes with
paclitaxel anaphase

19
paclitaxel microtubule stabilizing agent

methotrexate S phase inhibitor

methotrexate inhibits DHFR

treats
leucovorin myelosuppression

methotrexate folic acid analog

20
mercaptopurine activated by hypoxanthine-guanine
phosphoribosyltransferase (HGPRT)
(6-MP)

mercaptopurine inhibits many enzymes involved in


purine metabolism
(6-MP)

leuprolide treatment for endometriosis

treatment for BPH and precocious


leuprolide puberty

leuprolide stimulates release of FSH and LH

21
GnRH agonist used to treat prostate
leuprolide cancer

produced by virally infected cells to prevent infection


interferon alpha of adjacent cells

used to treat CML, malignant myeloma, kaposi


interferon alpha sarcoma, hairy cell leukemia

interferon alpha recombinantly produced cytokine

used to antagonize residual


flutamide androgens after orchiectomy

22
side effects include gynecomastia
flutamide and libido changes

flutamide androgen receptor antagonist

fluorouracil S phase antimetabolite

causes
fluorouracil myelosuppression

fluorouracil inhibits thymidylate synthase

23
used to treat colon cancer and basal
fluorouracil cell carcinoma

etoposide G2 phase inhibitor

causes double stranded breaks in


etoposide DNA

etoposide inhibits topoisomerase II

etoposide used to treat small cell carcinoma of the lung and


prostate and testicular cancers

24
intercalates in DNA to reduce
doxorubicin replication and transcription

doxorubicin causes dilated cardiomyopathy

daunorubicin used to treat AML

cyclophosphamide causes hemorrhagic cystitis

alkylating agent used to treat


cyclophosphamide cancers

25
cisplatin alkylating agent

causes nephrotoxicity and acoustic


cisplatin nerve damage

carmustine alkylating agent that causes DNA cross-linking and


strand breaks

carmustine used to treat brain tumors, highly lipophilic


nitrosourea drug

bleomycin mixture of glycoproteins that produce free radicals


upon binding DNA

26
bleomycin causes strand breaks in DNA

bleomycin G2 phase inhibitor

bleomycin can cause pulmonary fibrosis

anastrozole inhibitor of steroid synthesis

inhibits conversion of
anastrozole androstenedione to estrone

27
blocks conversion of cholesterol to
aminoglutethimide pregnenolone

anastrazole aromatase inhibitor

zidovudine inhibits viral reverse transcriptase

zidovudine chain terminator

given to prevent transmission of


zidovudine HIV to neonates

28
vancomycin used to treat MRSA

vancomycin used to treat c. difficile

rapid IV infusion causes red man


vancomycin syndrome

TMP-SMX blocks folate synthesis

TMP-SMX can cause megaloblastic anemia

29
do not give to pts with G6PDH
TMP-SMX deficiency

trimethoprim blocks DHFR

sulfamethoxazole blocks dihydropteroate synthase

tetracycline inhibits 30s ribosome

tetracycline bacteriostatic drug

30
tetracycline CI in pregnant women due to bone dysplasia and
dental enamel defects

streptogramins p450 inhibitor

arthralgias and
streptogramins myalgias

streptogramins used to treat MRSA and VRE

inhibits DNA-dependent RNA


rifampin polymerase

31
imparts red-orange color to
rifampin secretions

ribavirin guanosine analog

ribavirin inibits steps in RNA synthesis

used to treat viral hemorrhagic


ribavirin fevers and hepatitis C

ribavirin used to treat RSV

32
quinine blocks DNA replication and RNA transcription in p.
falciparum within RBCs

quinine causes cinchonism

headache, vertigo, blurry vision,


cinchonism tinnitus

used for prophylaxis of p. falciparum


mefloquine due to low SE

quinine used for malaria

33
stimulates nicotinic receptors in
pyrantel pamoate nematodes

used for fluke and tapeworm


praziquantel infections

cationic detergent that disrupts


polymyxin b bacterial membranes

causes neurotoxicity and acute


polymyxin b tubular necrosis

polymyxin b only used topically

34
penicillins inhibits transpeptidation step in bacterial cell wall
synthesis

neuraminidase inhibitor that


oseltamivir prevent viral spreading

used against influenza


oseltamivir a

nystatin disrupts fungal membrane permeability by binding


to ergosterol

used to treat oral candidiasis and


nystatin diaper rash

35
can cause hemolysis in G6PDH
nitrofurantoin deficient patients

nitrofurantoin can accumulate to toxic levels in patients with renal


failure

urinary antiseptic that requires


nitrofurantoin acidification

nifurtimox used to treat chagas disease

NNRTI used to treat


nevirapine HIV

36
neomycin used to treat hepatic encephalopathy

prevents accumulation of
neomycin nitrogenous microbial metabolites

metronidazole activated by anaerobes and parasites

metronidazole interferes with nucleic acid synthesis

metronidazole used to treat amebiasis, trichomoniasis, giariasis,


and c. diff

37
bulky R-group prevents degradation
methicillin by penicillinase

bulky R-group prevents degradation


nafcillin by penicillinase

bulky R-group prevents degradation


dicloxacillin by penicillinase

methi, naf, diclox beta lactams

mebendazole inhibits microtubule synthesis and glucose uptake by


helminths

38
mebendazole used to treat pinworms

albuterol selective b2 agonist

atenolol selective b1 blocker

acebutolol selective b1 blocker

metoprolol selective b1 blocker

39
depresses cough center in the
detromethrophan medulla

metoclopramide facilitates acetylcholine while blocking dopamine in


the enteric nervous system

SE are sedation, diarrhea,


metoclopramide extrapyramidal symptoms

prokinetic agent used to block


metoclopramide emesis

blocks D2 receptors in the area


metoclopramide postrema

40
misoprostol PGE analog

misoprostol decreases gastric acid production, increases mucus


production

eicosanoid preparation used for pts


misoprostol taking lots of NSAIDs

omeprazole H/K ATPase inhibitor

serotonin-3 inhibitor that acts at the


ondansetron area postrema

41
requires acidic environment to
sucralfate polymerize

cannot be used with antacids or H2


sucralfate blockers

folic acid will correct anemia but not neuro sx associated with
b12 deficiency

EPO recombinant drug used for anemia

orally active inhibitor of


aminocaproic acid plasminogen activation

42
aminocaproic acid inhibits fibrinolysis

used for acute bleeding in


aminocaproic acid hemophilic patients

antibody against glycoprotein 2b/3a


abciximab receptor

abciximab prevents platelet activation

anticoagulant preventing restenosis


abciximab after angioplasty

43
benztropine antimuscarinic

CI are prostatic hyperplasia, GI


benztropine obstruction, glaucoma

benztropine antimuscarinic used to treat tremors and rigidity in


parkinsons, but does nothing for bradykinesia

antibody to Rh(D) antigen that


RhoGAM opsonizes

probenecid competes with uric acid for reabsorption in the


proximal tubule

44
probenecid inhibits secretion of weak acids

sulfinpyrazone acts simliarly to probenecid

methylsergide blocks serotonin receptors

causes fibroplasia of
methylsergide retroperitoneum and
subendocardium

methylsergide used to prevent migraines

45
binds IL-2 receptor on activated T
daclizumab cells

used for patients with renal


daclizumab allografts

bromocriptine D2 agonist

bromocriptine inhibits PRL release

inhibit histamine binding to H1


diphenhydramine receptors

46
diphenhydramine causes drowsiness

used for allergies and motion


diphenhydramine sickness

cromolyn sodium stabilizes mast cell membrane

lithium inhibits IP3 and DAG

causes tremor, hypothyroidism,


lithium polydipsia, polyuria

47
stimulates the release of
methylphenidate catecholamines

phenytoin inducer of p450

carbamazepine inducer of p450

griseofulvin inducer of p450

rifampin inducer of p450

48
barbiturates inducer of p450

penicillins bactericidal

cephalosporins bactericidal

vancomycin bactericidal

aminoglycosides bactericidal

49
fluoroquinolones bactericidal

metronidazole bactericidal

calcium channel causes cutaneous flushing


blockers

adenosine causes cutaneous flushing

vancomycin causes cutaneous flushing

50
metronidazole causes disulfiram-like reaction

cephalosporins causes disulfiram-like reaction

procarbazine causes disulfiram-like reaction

nitrous oxide has a high MAC

phenelzine MAOI

51
tranylcypromine MAOI

isocarboxazid MAOI

MAOI + SSRI serotonin syndrome

inhibits breakdown of amine


MAOI neurotransmitters

mebendazole microtubule inhibitor

52
thiabendazole microtubule inhibitor

paclitaxel microtubule inhibitor

vincristine microtubule inhibitor

colchicine microtubule inhibitor

griseofulvin microtubule inhibitor

53
hydralazine SLE like syndrome

procainamide SLE like syndrome

isoniazid SLE like syndrome

phenytoin SLE like syndrome

massive hepatic
halothane necrosis

54
massive hepatic
acetaminophen necrosis

massive hepatic
valproic acid necrosis

cimetidine p450 inhibitor

ketoconazole p450 inhibitor

erythromycin p450 inhibitor

55
cimetidine gynecomastia

ketoconazole gynecomastia

spironolactone gynecomastia

bleomycin pulmonary fibrosis

amiodarone pulmonary fibrosis

56
busulfan pulmonary fibrosis

ototoxic and
aminoglycosides
nephrotoxic

ototoxic and
loop diuretics nephrotoxic

ototoxic and
cisplatin nephrotoxic

vancomycin mildly ototoxic and nephrotoxic

57
penicillamine used to treat wilson disease

penicillamine used to treat RA

used to treat copper toxicity bc it is a


penicillamine chelator

anticholinesterases used in chemical


organophosphates warfare

antidote for anticholinesterases such


pralidoxime as organophosphates

58
naloxone mu opioid receptor antagonist

naloxone used to treat opioid overdose

phenobarbital binds GABA receptors

increases the duration of chloride


phenobarbital channel opening

used to treat tonic-clonic seizures


phenobarbital and crigler-najjar

59
phenytoin interferes with folate absorption

phenytoin SE are gingival hyperplasia, hirsutism, anemia, and


birth defects

phenytoin class 1b antiarrhythmic

risperidone blocks D2 and serotonin-2 receptors

risperidone causes high sedation

60
atypical antipsychotic with lots of
risperidone extrapyramidal SE

forestalls the use of levodopa in


ropinirole parkinson's disease

methanol causes damage by being converted to formaldehyde


in the liver

retinal damage, blindness, metabolic


methanol acidosis, coma

antagonizes benzodiazepines and


flumazenil zolpidem

61
flumazenil used for benzodiazepine overdose

causes metabolic acidosis and precipitation of


ethylene glycol oxalate crystals in the kidney

chelates metals to keep them from


dimercaprol damaging proteins

succimer orally active metal chelator

dimercaprol used to treat heavy metal poisoning

62
digibind fab fragment antibody

rapid infusion causes hypotensive


deferoxamine shock

deferoxamine used to treat acute iron toxicity

dantrolene decreases the release of calcium from the


sarcoplasmic reticulum

used to treat malignant


dantrolene hyperthermia

63
selegiline inhibits MAO-B

MAO-B degrades dopamine

selegiline inhibits degradation of dopamine in CNS, used with


levodopa for parkinson's

thiopental ultra-short acting barbiturate used to induce surgical


anesthesia

alprazolam intermediate-acting benzodiazepine used for panic


disorder and phobias

64
protects against fulminant hepatic
n-acetylcysteine failure

n-acetylcysteine used for acetaminophen overdose

carvedilol used for CHF

nonselective beta blocker and


carvedilol alpha-1 blocker

blocks sodium
amiodarone channels

65
amiodarone corneal microdeposits

amiodarone class III antiarrythmic

short acting agent given IV for AV


adenosine nodal arrhythmias

spironolactone potassium sparing diuretic

spironolactone aldosterone antagonist

66
spironolactone functions at the collecting tubule

nitroprusside stimulates guanyl cyclase

increases cGMP in vascular smooth


nitroprusside muscle

minoxidil direct-acting vasodilator

used topically bc of benefit of


minoxidil hypertrichosis

67
bind bile acids to prevent
cholestyramine enterohepatic recycling

fexofenadine nonsedating antihistaminic

loratadine nonsedating antihistaminic

ipratropium dry mouth side effect

antimuscarinic for COPD and


ipratropium asthma

68
salmeterol may cause tremors and arrhythmias

theophylline methylxanthine used for asthma

theophylline inhibits phosphodiesterase

theophylline inhibits conversion of cAMP to AMP

octreotide used to treat carcinoid, gastrinoma, somatotropic


pituitary adenoma

69
inhibits iodination step of thyroid
propylthiouracil hormone synthesis

same as PTU but crosses placenta


methimazole and enters breast milk

estrogen partial
raloxifene agonist

does not increase the risk of


raloxifene endometrial cancer

tamoxifen increases risk of endometrial cancer

70
rapid onset
repaglinide sulfonylurea

binds potassium channels to


repaglinide facilitate insulin release

glitazones increase insulin sensitivity

glitazones stimulate PPAR-gamma receptor

troglitazone hepatotoxic

71
stimulate closure of potassium
sulfonylureas channels

sulfonylureas glyburide and glipizide

sulfonylureas cause release of preformed insulin

acyclovir used to treat herpes

acyclovir guanosine analog

72
activated by thymidine kinase of the
acyclovir virus it treats

acyclovir functions as a chain terminator when incorporated


into viral DNA

prophylaxis against influenza A and


amantadine rubella

amantidine inhibits fusion of viral particles within endosome of


the cell

amantidine not effective against influenza B

73
amantidine binds to M2 protein

disrupts fungal membranes by


amphotericin B binding ergosterol

blocks binding of progesterone to


mifepristone cytoplasmic receptors

extended spectrum penicillin used to


ampicillin treat gram negatives

aztreonam b-lactamase resistant monobactam

74
used only with aminoglycosides
aztreonam against gram negative rods

cannot be used against gram


aztreonam positives or anaerobic bacteria

bacitraicin inhibits bacterial cell wall synthesis

used against enterobacter and


piperacillin pseudomonas

used against enterobacter and


carbenicillin pseudomonas

75
used against enterobacter and
ticarcillin pseudomonas

ceftriaxone used for septic meningitis

used to treat
cefixime gonnorhea

gray baby syndrome in babies deficient in hepatic


chloramphenicol gluconosyltransferase

chloramphenicol aplastic anemia

76
fludrocortisone used in postadrenalectomy therapy

chloroquine primary drug for acute malaria

chloroquine disrupts hemoglobin breakdown, with toxic


accumulation of heme in RBC

beta lactamase
clavulanic acid
inhibitor

beta lactamase
sulbactam inhibitor

77
beta lactamase
tazobactam inhibitor

clindamycin bacteriostatic at the 50s ribosome

treatment of
clindamycin bacteroides

didanosine (ddI) dose-limiting pancreatitis

inhibits reverse transcriptase of


lamivudine hepatitis B

78
erythromycin bacteriostatic inhibitor of 50s

erythromycin macrolide

azithromycin macrolide

clarithromycin macrolide

GI irritation and acute cholestatic


erythromycin hepatitis

79
metformin biguanide compound

metformin increases peripheral glycolysis

blocks negative feedback at the


clomiphene pituitary

used for diagnosis of addison's


cosyntropin disease

danazol inhibitor of p450

80
danazol used for endometriosis and fibrocystic disease of the
breast

desmopressin selective V2 agonist

vasopression V1 and V2 agonist

vasopressin used to treat esophageal varices

clear cell carcinoma of the vagina in


DES daughters

81
lowers risk of coronary disease, slows osteoporosis,
ethinyl estradiol/mestranol ameliorates hot flashes

increased risk of breast and ovarian


HRT cancer

zileutin inhibits leukotriene synthesis

LTD4 and LTE4


monteleukast antagonist

acarbose inhibits a-galactosidase

82
bisphosphonates esophageal ulcerations

used to treat hyperprolactinemia


bromocriptine due to pituitary adenoma

bromocriptine ergot alkaloid

diphenoxylate suppress GI motility

loperamide suppress GI motility

83
cisapride stimulates peristalsis by release of Ach from
myenteric plexus

cisapride long QT

magnesium hydroxide laxative antacid

aluminum hydroxide constipating antacid

acts to stimulate chemoreceptor


ipecac syrup trigger zone of the medulla

84
cimetidine gynecomastia and galactorrhea

cimetidine p450 inhibitor

calcium carbonate hypercalcemic alkalosis

calcium carbonate renal calculi

used with metronidazole and tetracycline for PUD


bismuth subsalicylate caused by h.pylori

85
interferes with vitamin K dependent
warfarin clotting factors

converts fibrin-bound plasminogen


alteplase to plasmin

ticlopidine platelet antiaggregant

ticlopidine interferes with binding of fibrin to Gp2b/3a receptor


on platelets

catalyzes conversion of plasminogen


streptokinase to plasmin

86
fluconazole inhibits formation of ergosterol

prophylaxis against cryptococcus


fluconazole neoformans

fluconazole used to treat oral candidiasis

fluoroquinolones bactericidal inhibitor of DNA gyrase

used for gram negative rods, some gram positives,


fluoroquinolones and neisseria

87
fluoroquinolones bad for cartilage

sargramostim recombinant GM-CSF

filgrastim G-CSF

hydroxyurea used for sickle cell crisis

hydroxyurea increases levels of HbF

88
hydroxyurea inhbits DNA synthesis by blocking conversion of
ribonucleotides to deoxyribonucleotides

foscarnet treats CMV

foscarnet inhibits viral DNA polymerase

ganciclovir metabolized by viral transferases

requires phosphorylation by viral


ganciclovir kinases to work

89
guanosine analog converted by CMV
ganciclovir to triphosphorylated form

SE: neutropenia, leukopenia,


ganciclovir thrombocytopenia

griseofulvin keratinized tissue

griseofulvin ringworm

griseofulvin binds tubulin

90
carbapenem given with cliastatin

carbapenem used against gram positive cocci, gram negative rods,


and anaerobes

ritonavir inhibit protease in the HIV pol gene

isoniazid inhibits synthesis of mycolic acid

isoniazid SE neuritis and hepatitis

91
ethambutol TB

pyrazinamide TB

rifampin TB

streptomycin TB

sulfonamides stevens-johnson

92
ethosuxamide stevens-johnson

lamotrigine stevens-johnson

penicillins erythema multiforme

barbiturates erythema multiforme

salicylates erythema multiforme

93
hydantoins erythema multiforme

antimalarials erythema multiforme

sulfonamides G6PDH

isoniazid G6PDH

primaquine G6PDH

94
tetracycline photosensitivity

amiodarone photosensitivity

sulfonamides photosensitivity

bethanechol muscarinic agonist

carbachol nicotinic and muscarinic agonist

95
ephedrine ma-huang

adrenergic antagonist (alpha


phenoxybenzamine receptors)

used in diagnosing
phentolamine pheochromocytoma

onchocera volvulus and


ivermectin strongyloides stercoralis

increases GABA transmission in the


ivermectin worm

96
interfere with fungal cell wall
ketoconazole synthesis

pilocarpine treatment of glaucoma

pilocarpine muscarinic agonist

prazosin first dose syncope

prazosin miosis

97
pyridostigmine used for tubocurarine toxicity

competitive cholinergic antagonist


scopolamine used for motion sickness

succinylcholine muscle relaxant

nicotinic agonist that opens sodium


succinylcholine channels

nondepolarizing neuromuscular
tubocurarine ganglionic blockers

98
acetazolamide inhibits carbonic anhydrase in the proximal
convoluted tubule

acetazolamide metabolic acidosis

give to alkalinize the urine in aspirin


acetazolamide toxicity

block sodium channels in the


amiloride cortical collecting tubules

amiloride hyperkalemic metabolic acidosis

99
captopril inhibit breakdown of bradykinin

should be given with


ketamine benzodiazepines

gabapentin partial seizures

ethosuxamide inhbits T-type calcium channels

inhibits conversion of levodopa to


entacapone 3-0-methyldopa

100
hypokalemia, alkalosis,
HCTZ hyperuricemia, hyperlipidemia

captopril functions at the collecting tubules

losartan functions at the collecting tubules

losartan CI in pregnancy

captopril CI in pregnancy

101