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# Common Conversions

:

1 Liter = 1000 Milliliters 1 Gram = 1000 Milligrams 1 Milligram = 1000 Micrograms 1 Kilogram = 2.2 pounds

Methods of Calculation

Any of the following three methods can be used to perform drug calculations. Please review all three methods and select the one that works for you. It is important to practice the method that you prefer to become proficient in calculating drug dosages. Remember: Before doing the calculation, convert units of measurement to one system. I. Basic Formula: Frequently used to calculate drug dosages. D (Desired dose) H (Dose on hand) V (Vehicle-tablet or liquid) D x V = Amount to Give H D = dose ordered or desired dose H = dose on container label or dose on hand V = form and amount in which drug comes (tablet, capsule, liquid) Example: Order-Dilantin 50 mg p.o. TID Drug available-Dilantin 125 mg/5ml D=50 mg H=125 mg V=5 ml

50 250 x5= = 2 ml 125 125 II. Ratio & Proportion: Oldest method used in calculating dosage. Known H : V :: Desired D : X

Means Extremes III. IV. Left side are known quantities Right side is desired dose and amount to give

IX. QD Drug Available .Digoxin 0. H D = V X HX = DV X= DV H Example: Order . :: 1000 : X 250X = 1000 X= 1000 250 XII.25 = 1 X XX. Cross multiply and solve for X. Fractional Equation X = 4 capsules H D = V X XIV. X. Multiply the means and the extremes HX = DV X= DV H Example: Order-Keflex 1 gm p.125X = 0.0.125 mg 0.125 V=1 tablet .125 0.25 0.125 mg per tablet D=0.25 mg p.o. D=1 gm (note: need to convert to milligrams) 1 gm = 1000 mg H=250 mg V=1 capsule 250 : 1 XI.o. XIII.V.25 X= 0.25 mg H=0. 0. BID Drug available-Keflex 250 mg per capsule VIII.

Dopamine.25 (31gtts/min) 8 hrs x 60 480 XXIII.6 mcg/min NTG 50 mg/250 cc 1 cc/hr = 3.3 mcg/min G. X = 2 tablets Intravenous Flow Rate Calculation (two methods) Two Step Step 1 . mcg/min (For example .) . mcg/kg/min (For example .XXII.Lidocaine. How to Calculate Continuous Infusions A. Pronestyl) Solution cc x 60 min/hr x mg/min = cc/hr Drug mg Drug mg x cc/hr = mg/hr Solution cc x 60 min/hr D. etc.25 (31 gtts/min) 60 One Step 1000 x 15 15. Nipride.Amount of fluid divided by hours to administer = ml/hr ml/hr x gtts/ml(IV set) Step 2 = gtts/min 60 min One Step amount of fluid x drops/milliliter (IV set) hours to administer x minutes/hour (60) Example: 1000 ml over 8 hrs IV set = 15 gtts/ml Two Step Step 1 1000 = 125 8 Rule of Thumb Lidocaine. mg/min (For example . Dobutamine. XXI.Nitroglycerin) Solution cc x 60 min/hr x mcg/min = cc/hr Drug mcg Drug mcg x cc/hr = mcg/hr Solution cc x 60 min/hr Rule of Thumb NTG 100 mg/250 cc 1 cc/hr = 6.000 = = 31. Pronestyl 2 gms/250 cc D5W 1 mg = 7 cc/hr 2 mg = 15 cc/hr 3 mg = 22 cc/hr 4 mg = 30 cc/hr 125 x 15 Step 2 = 31.

How many mcg/kg/min of Nipride is the patient receiving? 100.500. To calculate cc/hr (gtts/min) Solution cc x 60 min/hr x kg x mcg/kg/min = cc/hr Drug mcg Example: Dopamine 400 mg/250 cc D5W to start at 5 mcg/kg/min. 250 cc x 60 min x 86.000 mcg x 25 cc/hr 2. Patient¶s weight is 190 lbs. 26. The patient¶s weight is 143 lbs.5 mcg/kg/min 250 cc x 60 min x 65 kg 975. NOW DO THE REST! E.4 x 5 mcg/kg/min = 16. you can do anything! D.54 mcg/kg/min Patients¶s weight in kg (75 kg) = 3.000 = = 2.6 mcg/cc/min C.000 A. For example: 400mg of Dopamine in 250 cc D5W = 1600 mcg/cc 60 min/hr = 26. Once you do this step.6 is the dosage concentration for Dopamine in mcg/cc/min based on having 400 mg in 250 cc of IV fluid. If you have a 75 kg patient for example.5 mcg/kg/min (rounded down) .6 mcg/cc/min x 10 cc on pump = 3. and the IV pump is set at 25 cc/hr.2 cc/hr 400. How to calculate mcg/kg/min if you know the rate of the infusion Dosage (in mcg/cc/min) x rate on pump = mcg/kg/min Patient¶s weight in kg B...000 mcg 4. 26. You need this to calculate this dosage concentration first for all drug calculations.1. To calculate mcg/kg/min Drug mcg/ x cc/hr = mcg/kg/min Solution cc x 60 min/hr x kg Example: Nipride 100 mg/250 cc D5W was ordered to decrease your patient¶s blood pressure.

6 is the dosage concentration for Dopamine in mcg/cc/min based on having 400 mg in 250 cc of IV fluid.6 mcg/cc/min x 10 cc on pump = 3. For example: H. 2800 milliliters to liters 7. For example: 10 cc x 26. For example: M.5 mcg/kg/min x 75 kg = 9. You need this to calculate this dosage concentration first for all drug calculations. 400 mg Dopamine in 250 cc D5W = 26. 26.86 cc 26.5 grams to milligrams 3. 10 milligrams to micrograms 4. How to calculate drips in cc per hour when you know the mcg/kg/min that is ordered or desired mcg/kg/min x patient¶s weight in kg = rate on pump dosage concentration in mcg/cc/min G. NOW DO THE REST!! P. ALWAYS WORK THE EQUATION BACKWARDS AGAIN TO DOUBLE CHECK YOUR MATH! J. Practice Problems: 1.6 mcg/cc/min N. If you have a 75 kg patient for example 26. Once you do this step.F. 500 milligrams to grams 5.5 liters to milliliters 2.6 mcg/cc/min = 10 cc rounded up I.5 mcg/kg/min 75 Kg Dosage (in mcg/cc/min) x rate on pump = mcg/kg/min Patient¶s weight in kg L. 400mg of Dopamine in 250 cc D5W = 1600 mcg/cc 60 min/hr = 26. 7. you can do anything! O.6 mcg/cc/min = 3. 165 pounds to kilograms . 2. 7500 micrograms to milligrams 6.6 mcg/cc/min 3.54 mcg/kg/min Patients¶s weight in kg (75 kg) Now do some practice exercises to check what you learned A.

5 mg per tablet 2. Practice Problems: 1. Order-Dicloxacillin 125 mg Drug Available-Dicloxacillin 62. The drug is ordered every 6 hours. Order-1000 ml over 6 hrs 2.6 gm Drug available-Tagamet 300 mg per tablet 3. 1.5 gm Drug available-Ampicillin 250 mg per 5 ml 5. A Nitroglycerin drip (100mg in 250 cc D5W) is infusing on your patient at 28 cc/hour on the infusion pump. How many milligrams will be given for each dose? C. Order-Ampicillin 0. Practice Problems: Use the method you have chosen to calculate the amount to give.520 mg of a medication in a 24 hour period. Order-Phenobarbital 60 mg Drug available-Phenobarbital 15 mg per tablet 4. Order-100 ml over 20 min. The patient¶s weight is 200 pounds.5 mg per 5 ml 6. A Dopamine drip (400mg in 250 cc of IV fluid) is infusing on your 80 kg patient at 20 cc/hour. Order-500 ml over 4 hrs 3. Order-Dexamethasone 1 mg Drug available-Dexamethasone 0.8. Dopamine 400 mg in 250 cc D5W to infuse at 5 mcg/kg/min. What is the rate you would begin the infusion on the infusion pump? 4. Order-Tagamet 0. How many cc/hour would this be on an infusion pump? 2. Order-Medrol 75 mg IM Drug Available-Medrol 125 mg per 2 ml 7. Order. A procainamide drip is ordered (2gms in 250 cc D5W) to infuse at 4 mg/min. The patient weighs 165 pounds. IV set 15 gtts/ml IV set 10 gtts/ml IV set 15 gtts/ml D. Order-Lidocaine 1 mg per kg Patient¶s weight is 152 pounds 8. The order is to begin the infusion at 20 mcg/min. . Calculate the drip rate in cc/hour for which the infusion pump will be set at. How many mcg/min is your patient receiving? 5. A Nitroglycerin drip is ordered for your patient to control his chest pain. 80 kilograms to pounds B. The concentration is 100 mg in 250 cc D5W. How many mcg/kg/min are infusing for this patient? 3. Practice Problems: 1.

The Lidocaine concentration is 2 grams in 250 cc of D5W. 75 kg 8. 2 tablets 3.65 mcg/kg/min 3. 20. 30 cc/hr 6. 17 cc/hr 2.5 mg 6.000 mcg 4. 6. 7500 mg 3. 10 mL 6. 1. Practice Problems 1. 41. Practice Problems 1. 176 lbs B. 4 tablets 4. 2. 130 mg for 4 doses C. 7. 10 mL 5.6 (42) 2.5 mcg/min 5. 3 cc 4. 3 mg/min .6.5 gm 5. Practice Problems 1. 2500 mL 2. 69 kg = 69 mg 8. A Lidocaine drip is infusion on your 90 kg patient at 22 cc/hour.8 (21) 3. 75 D.2 mL 7. 0. How many mg/min is your patient receiving? Answers to Practice Problems A. 2 tablets 2. 10. 186.8 L 7. Practice Problems 1.