Mechanism of Action


Adverse Reaction >Fine skeletal muscle tremor especially hands, >tachycardia, palpitations, >muscle cramps, >headache, >paradoxical bronchospasm, >angioedema, urticaria, hypotension and collapse.


Nursing Consideration >Monitor therapeutic effectiveness which is indicated by significant subjective improvement in pulmonary function within 60±90 min after drug administration.

*Salbutamol (Albuterol, Proventil, Repetabs)

>Synthetic sympathomimetic amine and moderately selective beta2adrenergic agonist with comparatively long action. Acts more prominently on beta2 receptors (particularly smooth muscles of bronchi, uterus, and vascular supply to skeletal muscles) than on beta1 (heart) receptors. Minimal or no effect on alpha -adrenergic receptors. Inhibits histamine release by mast cells.

>To prevent and relieve bronchospasm in patients with reversible obstructive airway disease

>Eclampsia and severe preeclampsia; intrauterine infection, intra-uterine foetal death, antepartum haemorrhage, placenta praevia and cord compression, threatened miscarriage, cardiac disease.

Potentially Fatal: Potentially serious hypokalaemia after large

> Monitor for: S&S of fine tremor in fingers, which may interfere with precision handwork; CNS stimulation, particularly in children 2±6 y, (hyperactivity, excitement,

>Consult physician about giving last albuterol dose several hours before bedtime. insomnia). and pulse oximetry. GI symptoms. tachycardia. pulmonary functions. >Lab tests: Periodic ABGs. Report promptly to physician. .doses nervousness. if drug-induced insomnia is a problem.

renal and respiratory failure (dose related. hyperpnea. Genprin. Antipyretic Analgesic (nonopioid) hypothalamus to block effects of endogenous pyrogen by inhibiting synthesis of the prostaglandin intermediary. ZORprin Classification: y y Action >Analgesic and antirheumatic effects are attributable to aspirin's ability to inhibit the synthesis of prostaglandins. hemorrhagic states. y y y Fever Inflammatory conditions rheumatic fever. chronic urticaria). and ensure that patient does not chew SR preparations. Bayer. Antipyretic effects are not fully understood. tachypnea. tetany. 1/2 Halfprin. important mediators of inflammation. confusion. Halfprin 81. Easprin. PMS-ASA (CAN). Inhibition of platelet aggregation y Reduction of risk of death or nonfatal MI in patients with history of infarction or unstable angina pectoris y y y y Anti-inflammatory Antirheumatic Antiplatelet y Do not crush. rheumatoid arthritis. Heartline. fever. Aspirin intolerance: Exacerbation of y Use cautiously with . 4 g in children) y Contraindication Contraindicated with allergy to salicylates or NSAIDs (more common with nasal polyps. but aspirin probably acts in the thermoregulatory center of the y Indication Mild to moderate pain y Adverse Effects Acute aspirin toxicity: Respiratory alkalosis. coma. Entrophen (CAN). CV collapse. y Reduction of risk of recurrent TIAs or stroke in males with history of TIA due to fibrin platelet emboli y Give drug with full glass of water to reduce risk of tablet or capsule lodging in the esophagus. bleeding ulcers. Norwich. metabolic acidosis. Novasen (CAN). a rare but fatal disorder. asthma. blood coagulation defects. hypoprothrombine mia. vitamin K deficiency (increased risk of bleeding) Nursing responsibility y WARNING: Do not use in children and teenagers to treat chickenpox or flu symptoms without review for Reye s syndrome. allergy to tartrazine (cross-sensitivity to aspirin is common).Drug Name Aspirin Apo-ASA (CAN). pulmonary edema. hemophilia. 20 25 g in adults. osteoarthritis Give drug with food or after meals if GI upset occurs. Aspergum. seizures. excitement. asterixis. Empirin. hemorrhage. Ecotrin.

children with fever accompanied by dehydration. supportive therapy. antepartal and postpartal hemorrhage. vomiting. prolonged gestation. hepatotoxicity y impaired renal function. difficulty hearing. pregnancy (maternal anemia. a potent vasoconstrictor and inducer of platelet aggregation. This effect occurs at low doses and lasts for the life of the platelet (8 days). chickenpox. heartburn. rhinitis (with nasal polyps. nausea. y y MI prophylaxis Unlabeled use: Prophylaxis against cataract formation with long-term use y bronchospasm. Higher doses inhibit the synthesis of prostacyclin.y Salicylate is attributable to the inhibition of platelet synthesis of thromboxane A2. anorexia. hemostatic defects y Hypersensitivity: Anaphylactoid reactions to anaphylactic shock y Take extra precautions to keep this drug out of the reach of children. asthma. induction of emesis. this drug can be very dangerous for children. epigastric discomfort. a potent vasodilator and inhibitor of platelet aggregation. surgery scheduled within 1 wk. y WARNING: Institute emergency procedures if overdose occurs: Gastric lavage. and prolonged labor have been reported. Hematologic: Occult blood loss. dyspepsia. tinnitus. rhinitis) GI: Nausea. activated charcoal. y Use the drug only . readily y Do not use aspirin that has a strong vinegar-like odor. influenza (risk of Reye's syndrome in children and teenagers). y Salicylism: Dizziness.

Avoid the use of other over-the-counter drugs while taking this drug. lactation. y y as suggested.diarrhea. Many of these drugs contain aspirin. Take the drug with food or after meals if GI upset occurs. Price does not reflect effectiveness. stillbirths. Do not cut. maternal ingestion of aspirin during late pregnancy has been associated with the following adverse fetal effects: low birth weight. crush. mental confusion. and serious overdose can occur. or chew sustainedrelease products. increased intracranial hemorrhage. possibly teratogenic. avoid overdose. lassitude (dose related) crosses the placenta. neonatal death). y You may . y Over-the-counter aspirins are equivalent.

abdominal pain. nausea. heartburn (take drug with food). . y Report ringing in the ears. gum bleeding (related to aspirin's effects on blood clotting). confusion. easy bruising. GI upset. rapid or difficult breathing. bloody stools. vomiting. dizziness.experience these side effects: Nausea.

candidiasis or joint. y With large doses or prolonged therapy monitor superinfection .Drug Name Generic name: Ceftriaxone sodium Brand name: Rocephine y Action Thirdgeneration cephalosporin that inhibits cell-wall synthesis. y Indication Uncomplicated gonococcal vulvovaginitis y y y y Adverse Effects CNS: fever. skin. headache. induration. bone GU: genital pruritus. Therapy may begin pending test results. intraabdominal. tenderness at injection Meningitis site. infection. pseudomembranous UTI. leukopenia septicemia Skin: pain. skin structure eosinophilia. Vit. carditis. K stores. anaphylaxis. usually bactericidal. K synthesis or low vit. and arthritis from penicillin G-refractory Lyme disease Nursing responsibility y Monitor PT and INR in patients with impaired vit. chills Acute bacterial otitis media Contraindication Contraindicated in patints hypersensitive to drug or other cephalosporins y Probenecid y Neurologic complications. gynecologic. dizziness CV: phlebitis. K may be needed y Obtain specimen for culture and sensitivity tests before first dose. lower colitis respiratory tract. rash. pruritus Other: hypersensitivity Perioperative reactions. GI: diarrhea. promoting osmotic instability. serum prevention sickness. or Hema: thrombocytosis. especially in high risk patients .