57 views

Uploaded by Baharnarenj11

- 1 Nonlinear Regression
- Statistics
- Forecasting Using Eviews
- BS INdi
- Rfree and the Rfree Ratio
- no 2
- Desmos User Guide
- Ch03 Guan Cm Aise Ppt
- Hetrosadastisity
- Appendix V
- Annex 5 - Linear Regression Model Results
- Tariq Project Report-24!06!2011
- Back Seat Drivers?: Does the public affect industrial policy in Canada
- CBE486/586 Syllabus Fall 2016
- 09 Inference for Regression Part1
- Paper Kopsidas Odysseas
- se
- ch 3
- Uji Regressions
- assignmentsession5 simpleregressionproblems

You are on page 1of 2

1. Introduction

In quantitative analysis, sometimes calibration curve is made by "weighted" regression analysis. The

basic concept of weighted regression curve is based on the hypothesis that variance of the data may

differ by the level of analyte. This issue is well discussed in "Statistics for Analytical Chemistry

(J.C.Miller and J.N.Miller, Ellis Horwood Ltd.,1988)".

Ordinary regression curve (for example, y=ax+b) is determined to minimize "deviation" from data

(xi, yi) points. In this example, deviation is (actual yi)-(y on the curve, corresponding to xi)=yi-

(axi+b). Such a and b that minimize the Sum of the deviation is selected (actually, square of

deviation is used for mathematical convenience - this is the least "square" regression).

For "weighted" regression curve, such a and b that minimize the Sum of (deviation/weight) is

selected. The typical use of weighted regression curve is described below.

(1) Example

These are typical error models. The left data series have relative errors and the right data series

have fixed errors. In the left, errors are proportional to level, whereas in the right errors are constant.

In the case like right, normal (non-weighted) regression makes sense (fundamentally, except for the

issue written in (2)a)). But, what if, in the left case, top calibration point accidentally has very large

http://homepage3.nifty.com/m_nw/rev006.htm 6/7/2011

Weighted Regression of Calibration Curve Seite 2 von 2

error?

This extreme case can present the problem. One can argue that there is something wrong with it,

because a very variable data point heavily affected the slope of the calibration curve.

a)Should calibration levels be 1, 2, 4, 8 or 2, 4, 6, 8?

b)Should variable data point regarded as less important?

Here, I will try to explain by focusing on b).

As claimed above, variable data points should be regarded as less important. It would be appropriate

to consider,

1. (step1)importance=less variance

2. (step2)In least squares regression, such calibration curve that minimizes the sum of the

deviation is calculated.

3. (step3)Should better calibration curve be such that minimizes the sum of the

(deviation/variance) ?

4. (step4)Regression method described in step3 is "weighted least squares regression", with the

weight of (1/variance), as written in section 2.

5. (step5)In this case, weighted least squares regression may be the better way of regression.

I think this is one of the ways to understand the practical meaning of weighted regression calibration

curve.

4. References

Statistics for Analytical Chemistry (J.C.Miller and J.N.Miller, Ellis Horwood Ltd.,1988)

To index page

http://homepage3.nifty.com/m_nw/rev006.htm 6/7/2011

- 1 Nonlinear RegressionUploaded byEmRan Leghari
- StatisticsUploaded byAbhijit Pathak
- Forecasting Using EviewsUploaded byLucia Spinei
- BS INdiUploaded byAkanksha Chaudhary
- Rfree and the Rfree RatioUploaded byrakesh1521
- no 2Uploaded byMeylinda Dwi Anjarwati
- Desmos User GuideUploaded byvarun
- Ch03 Guan Cm Aise PptUploaded byFlorensia Restian
- HetrosadastisityUploaded bystreet_rapperz
- Annex 5 - Linear Regression Model ResultsUploaded byRanga Perera
- Tariq Project Report-24!06!2011Uploaded byAli Haider
- CBE486/586 Syllabus Fall 2016Uploaded bySB216
- Appendix VUploaded byMalim Muhammad Siregar
- Back Seat Drivers?: Does the public affect industrial policy in CanadaUploaded bySean McConnachie
- 09 Inference for Regression Part1Uploaded byRama Dulce
- Paper Kopsidas OdysseasUploaded byΟδυσσεας Κοψιδας
- seUploaded byMahmoud Eldabah
- ch 3Uploaded byrichard dizon
- Uji RegressionsUploaded byFarid Raharja P
- assignmentsession5 simpleregressionproblemsUploaded byapi-106423440
- Malhotra Mr05 Ppt 17Uploaded byMeny Chavira
- posttes22Uploaded byNabila Saribanun
- The Business Outsourcing in Telecommunication Industry Case of PakistanUploaded byJolita Vveinhardt
- BCL07Uploaded byAN-NISA VIRGINIA AINUL
- Lamp IranUploaded byFandy Faidhul Attamimi
- KAJIAN TEORIUploaded byMahendra Adi
- 189754-ID-pengaruh-kompensasi-dan-motivasi-terhada.pdfUploaded bysuci dila ariska
- 1b line of fit by eyeUploaded byapi-254501788
- 13028-26330-1-SM.pdfUploaded bykirana
- A Study of Profitability and Liquidity of Chhimek Laghubitta Bikash Bank Limited, Everest Bank Limited and Janaki FinanceUploaded byDipesh Raj Pandey

- GMPUploaded byBaharnarenj11
- 0_Tugas rangkum jurnal Pengembangan metode analisis dng KCKT.PDFUploaded byAnnaF
- Chemical Drug Stability in Lipids, Modified Lipids, And Polyethylene Oxide-Containing FormulationsUploaded byBaharnarenj11
- Dissolution media simulating the intralumenal.pdfUploaded byBaharnarenj11
- A Dynamic in Vitro Lipolysis Model 1Uploaded byBaharnarenj11
- ABC Multidrug Transporters, Target for Modulation of Drug Pharmacokinetics and Drug-Drug InteractionsUploaded byBaharnarenj11
- Excipients fpr lipid formulations_AAPSWorkshopUploaded byBaharnarenj11

- mgt acc 106 pgs.pdfUploaded byGhettoopressed
- heizer_om10_ch04RRrUploaded byNaeldel Lizelle Cruz
- Jilid 3 Bil 1 Jun 2011-Factors Affecting Entrepreneurial Intentions Among MARA ProfUploaded byDev Sharma
- Airplane Costs PaperUploaded byFais Isaac
- Relative Valuation_Ashwath DamodaranUploaded byJigs Pad
- Intro EViewsUploaded byAji Bramantyojati
- Arch and GarchUploaded byJovan Njegic
- Set7Uploaded byArka
- Study BookUploaded byTom Joyner
- Help AnClimUploaded byhcsrecs
- AMJ Raja JohnsUploaded byhasnatmirza50
- QTAUploaded byNibraas Khan
- A Familiar Face(book) Profile Elements as Signals in an online social network.pdfUploaded byRiko Piliang
- Smart Tracking of SoC Verification Progress Using Synopsys Hierarchical Verification Plan (HVP)Uploaded bycharles taylor
- Research Notes 1 1 Attitudinal Equity and Market ShareUploaded byMarijana Simic
- IJETR032169Uploaded byerpublication
- Prem League StatsUploaded byRicardo Mateus
- Credit Risk Evaluation of Online Personal Loan Applicants: a Data Mining approachUploaded bydmitry8071
- Fin Policy & Capital StructureUploaded byGeorge Yihui Chen
- Correlation n RegressionUploaded bySantosh Pandey
- Comparative Economic Analysis of Rice Processing Methods in Benue State, NigeriaUploaded byIJEAB Journal
- ex2Uploaded byvpalazon
- Introductory Econometrics: Chapter 2 SlidesUploaded bysaraleeman
- 4-Strategic HR Practices and InnovatioonUploaded bySaravanan Subbiah
- Regionalindicators en (1)Uploaded byMariana Ionela
- Chapter 5 TEstUploaded byJeanneau Stadegaard
- THE IMPACT OF HEALTH-RELATED PROBLEM ON ACADEMIC ACHIEVEMENT OF STUDENTS: APPLICATION OF DUMMY VARIABLE REGRESSION MODELUploaded byIJAR Journal
- Dummy VariableUploaded byChristopher Allen
- Student User Guide for SpssUploaded byakita1610
- How to Use Stata 11.0 RevisedUploaded byporteger705