CURRICULUM VITAE & TEACHING DOSSIER CHRISTOPHER C LEIGHTON MD FRCPC SCHULICH SCHOOL OF MEDICINE UNIVERSITY OF WINDSOR CAMPUS 401 SUNSET

AVENUE, WINDSOR, ONTARIO N9B 3P4 TELEPHONE: 519-561-1411 FACSIMILE 519-561-1413 EMAIL: christopherleighton@cogeco.ca EDUCATION A. Postgraduate Education: 2008-present Certificate Program in Medical Education (PG CertMedEd), Centre for Medical Education, College of Medicine, University of Dundee, Scotland UK (ongoing). Clinical Neurology training in Cancer Pain Management, Dwight Moulin, Professor of Neurology, University of Western Ontario Clinical Epidemiology and Biostatistic MSc Program (part-time), University of Western Ontario Completed requirements for Certificate in Epidemiology/Biostatistics. Fellowship in Radiation Oncology – Clinical Fellowship Diploma Princess Margaret Hospital University of Toronto Clinical Supervisor: Dr. Bernard Cummings Focus: Gastrointestinal, Head and Neck, Lymphomas Radiation Oncology Residency Program London Regional Cancer Centre University of Western Ontario Degree: FRCPC Comprehensive Internal Medicine Internship, The Wellesley Hospital, Toronto, Ontario Program Director: Dr. Philip Nicol Rotations in ICU, Cardiology/CCU, Infectious Disease, Hematology/Medical Oncology,

2005

2000-2005

1996-1997

1993-1996

1992-1993

Christopher C. Leighton MD, FRCPC Neurology, General Medicine/HIV, Rheumatology, Emergency Medicine, and Urology B. Undergraduate Education: 1988-1992 Faculty of Medicine, Degree: MD University of Toronto, Clinical Clerkship: St. Michael’s Hospital Faculty of Science, Two years of Honours Biology, University of Windsor Honours Standing

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1986-1988

C. Qualifications and Certificates: 2006 1997 Methadone Exemption Licence, College of Physicians and Surgeons of Ontario (CPSO) Clinical Fellowship Diploma University of Toronto, Department of Radiation Oncology Princess Margaret Hospital Fellowship of the Royal College of Physicians and Surgeons, Radiation Oncology. Degree: FRCPC 1994 1993 1993 1992 Physician License State of Michigan, Board of Medicine FLEX I and II Licensing Exams Dearborn, Michigan Independent Practice License Province of Ontario (CPSO) ACLS certification Toronto, Ontario Licentiate of the Medical Council of Canada Qualifying Examination (LMCC-I)

Christopher C. Leighton MD, FRCPC

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ACADEMIC/EMPLOYMENT HISTORY 2010 – 2011 Schulich School of Medicine, Year One Windsor Program Course Coordinator for Introduction to Medicine and Patient-Centered Clinical Methods i) Committee Memberships: Year 1 & 2 Windsor Course Coordinators Introduction to Medicine Course Committee Clinical Methods Course Committee ii) Teaching Duties: a) Lecturer: Patient-Centred Clinical Methods (3 hours), Introduction to Medicine Growing Older/ Human Development Thread (3.5 hours) b) Clinical Instructor: Year One Patient-Centred Clinical Methods (78 hours, in progress), Year Two Patient-Centered Clinical Methods (Respiratory & Neurology; 6 hours) c) Facilitator/Tutor: Year 1 & 2Patient Centered Context: Applications and Integration (PCCIA), (32 hours) Schulich School of Medicine, Preclinical and Transition Period Coordinator (Years 1, 2, 4) Windsor Campus i) Committee Memberships: Year One & Two Windsor Course Coordinators Committee (Chair) Year One Windsor Course Coordinator: Introduction to Medicine Windsor Program Management Committee Undergraduate Curriculum Committee Preclerkship and Transition Period Committee Transition Period Planning Task Force Interprofessional Health Care Education Committee Introduction to Medicine Course Committee ii) Teaching Duties: a) Lecturer: Introduction to Medicine (3.5 hours), Digestion and Nutrition (2 hours) b) Clinical Instructor: Clinical Methods, Years 1 & 2 (70+ hours) c) Facilitator/Tutor: Facilitator, Patient Centred Context:Integration and Applications, Years One & Two (Year One: throughout year, 60+ hours)

2009 - 2010

Christopher C. Leighton MD, FRCPC

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2008-2009

Schulich School of Medicine, Year One Undergraduate Program Coordinator, Windsor Campus, Additional Roles: i) Committee Memberships: Year One Course Coordinators Committee (Chair) Year One Windsor Course Coordinator: Introduction to Medicine Windsor Program Management Committee Curriculum Committee Preclerkship and Transition Period Committee Introduction to Medicine Course Committee ii) Teaching Duties: Facilitator, Patient Centred Context: Integration and Applications, Year One (60 + hours) Clinical Instructor, Year One Clinical Methods, (60 + hours) Adjunct Professor, Department of Oncology, Schulich School of Medicine, University of Western Ontario, Windsor Campus (3 year appointment – July 2009 to June 2012) Independent Contractor Consultant, College of Physicians and Surgeons of Ontario, Complaints and Resolutions Division Palliative Care Consultant, Department Of Oncology, Windsor Regional Hospital Staff Radiation Oncologist, Windsor Regional Hospital, Department of Oncology. Practice: Central Nervous System and Gastrointestinal tumors; IMRT radiotherapy; Palliative RT. Palliative Medicine Consultant, Windsor and Essex County Hospice, August-October 2006. Assistant Professor, Senate Stream (full-time), Department of Oncology,Division of Radiation Oncology, University of Western Ontario. Practice: Gastrointestinal Cancer and Cancer Epidemiology Staff Radiation Oncologist (part-time), London Health Sciences Centre. Practice: Gastrointestinal Tumors and Cancer Epidemiology.

2007-present

2007

2006-2010 2006-2008

2006 1999-2005

1999-2005

Christopher C. Leighton MD, FRCPC 2002–2005 Faculty of Graduate Studies, Non-Core Membership,University Examiner for PhD Defenses, Department of Medical Biophysics University of Western Ontario

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1997-1999

Radiation Oncologist Windsor Regional Cancer Centre Practice: Gastrointestinal, Central Nervous System, and Lymphoreticular malignancies Clinical Fellow in Radiation Oncology, Princess Margaret Hospital Focus: Gastrointestinal and Head and Neck cancers Radiation Oncology Residency Program London Regional Cancer Centre University of Western Ontario London, Ontario Chief Resident (1994-95) Program Director: Dr. Barbara Fisher Comprehensive Internal Medicine Internship, The Wellesley Hospital, Toronto, Ontario. Program Director: Dr. Philip Nicol Rotations in ICU, Cardiology/CCU, Infectious Disease, Hematology/Medical Oncology, Neurology, General Medicine/HIV, Rheumatology, Emergency Medicine, and Urology

1996-1997

1993-1996

1992-1993

AWARDS, HONOURS, FELLOWSHIPS, SCHOLARSHIPS 2010 University Student Council Teaching Honour Roll Award. For high student evaluations, Year One & Two Undergraduate Medicine, Windsor Program University Student Council Teaching Honour Roll Award. For high student evaluations, Year One Medicine, Windsor Program. University Student Council Teaching Honour Roll Award. For high student evaluations, Year One Medicine, University of Western Ontario. Victoria Hospital Research Institute Award, Residents’ Research Day Victoria Hospital, London, Ontario For the best resident research presentation.

2009

2002-2003

1996

Christopher C. Leighton MD, FRCPC

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1994-1995 1992

Chief Resident, Department of Radiation Oncology University of Western Ontario McCormick Scholarship in Radiation Oncology, (For outstanding achievement during Radiation Oncology electives& research), Convocation Ceremonies, University of Toronto Ivan H. Smith Studentship in Clinical Oncology,Windsor Regional Cancer Centre, Clinical Clerkship, University of Toronto (8 week funded elective in oncology) R. I. Harris Undergraduate Award in Orthopaedics (for the best Orthopaedic Article in the University of Toronto Medical Journal), University of Toronto Ivan H. Smith Studentship in Clinical Oncology, Windsor Regional Cancer Centre, Year 2 Medicine, University of Toronto (8 week funded elective in oncology) Dean’s List (Honours Standing) University of Toronto, Faculty of Medicine President’s Roll (high academic standing) University of Windsor, Honours Biology Program. University of Windsor Scholarship (full tuition Award – 4 years). Renewed in 1987. Ontario Scholar Award, Provincial Award for high academic standing in Grade 13. Maths and Science Award, Highest aggregate standing in High School Grade 13 mathematics and science courses, Sandwich Secondary High School, LaSalle, ON

1991

1991

1990

1988-1990 1986-1988 1986

Christopher C. Leighton MD, FRCPC CONTINUING EDUCATION A. Professional Meetings/Conferences: 2011 Annual Meeting of the Canadian Pain Society, Niagara Falls, ON (booked)

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Canadian Association of Medical Education Annual Meeting, Toronto (planned) 2009 Annual Meeting of the Canadian Association for Medical Education, Edmonton, Alberta Canadian Pain Society Annual Meeting, Quebec City 2007 Annual Meeting of the American Society for Therapeutic Radiology and Oncology, Los Angeles, CA, October National Cancer Institute of Canada, Annual Meeting, Toronto, ON Annual Gastrointestinal Cancer Symposium, American Society of Clinical Oncology, Orlando, FL, January 2004 2003 Radiation Therapy Oncology Group (RTOG) Annual Meeting, New Orleans, January. Annual Meeting of the American Society for Therapeutic Radiology and Oncology, Salt Lake City, Utah Annual Meeting of the Canadian Association of Radiation Oncologists, Montreal, Quebec. 2003 National Cancer Institute of Canada (NCI-C) Annual Meeting, Toronto, November. Presentation of a randomized trial concept. RTOG Semi-Annual Meeting, Montreal, June. RTOG, Semi-Annual Meeting, Philadelphia, June RTOG Semi-Annual Meeting, Tampa

2003 2002 2001

Christopher C. Leighton MD, FRCPC

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2000 1999 1997 1996

Annual meeting of the National Cancer Institute— Canada (NCI-C), Toronto, ON. RTOG Semi-Annual Meeting, Philadelphia, PA RTOG Semi-Annual Meeting, Houston RTOG Semi-Annual Meeting, Washington DC

B. Continuing Education/Symposia: 2010 Grand Rounds, Schulich School of Medicine & Dentistry, Windsor Program: Cardiovascular Screening (1.5 hours) Neuro Pain Management (1.5 hours) PCOS (Endocrinology) (1.5 hours) Total: 4.5 MAINPRO M1 Credits Introduction to Using UWO Library Resources Workshop. Windsor Campus, Schulich School of Medicine & Dentistry. 1.5 MAINPRO M1 Credits Conquering Malignant Pain & Suffering: New Possibilities. Schulich School of Medicine & Dentistry. Windsor, Ontario. 6.5 MAINPRO-M1 Credits. (Chair of Scientific & Organizing Committee) Canadian Pain Society Annual Meeting, La Ville de Quebec (23 hours CPD) Canadian Association for Medical Education Annual Meeting, Edmonton, Alberta 2008 Advanced Learning in Palliative Medicine Conference, Canadian Society of Palliative Care Physicians, Ottawa Pain: Managing Their Pain, Not Their Expectations University of McMaster Online Learning, 1 MAINPRO-M1 Credit 2007 Annual meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO), Los Angeles, California

2009

Christopher C. Leighton MD, FRCPC 2006 2004 2003 Methadone Licensing Course, Windsor and Essex County Hospice, Instructor: Dr. Charmaine Jones Annual UWO Department of Oncology Research Day, May, London, Ontario. American Society for Therapeutic Radiology and Oncology (ASTRO) Annual Meeting, Salt Lake City, October American Society of Clinical Oncology (ASCO) Annual Meeting, Chicago, May European Society for Therapeutic Radiology and Oncology Annual Meeting (ESTRO), Prague, Czech Rep. 2001 European Society for Therapeutic Radiology and Oncology (ESTRO), Lisbon, Portugal American Society of Clinical Oncology Annual Meeting (ASCO), San Francisco 2000 Annual meeting of the American Society for Therapeutic Radiology and Oncology (ASTRO), Boston, October Biennial Canadian Neuro-oncology Meeting, Vancouver Annual Meeting of the European Society for Therapeutic Radiology and Oncology (ESTRO) Edinburgh, Scotland Biennial Canadian Neuro-oncology Meeting, Niagara-on-the Lake, Ontario “Genitourinary Oncology: Challenges For the Future”, Workshop, University of Toronto “Translating Physics into the Clinic”, Radiation Oncology Workshop, University of Toronto 1996 Annual Meeting of the European Society for Therapeutic Radiology and Oncology (ESTRO), Vienna, Austria

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2003

Christopher C. Leighton MD, FRCPC

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1995 1994

Pediatric Oncology Workshop Princess Margaret Hospital, Toronto Radiation Biology Workshop University of Toronto, Faculty of Medicine, “Clinical Aspects of Radiation Biology” American Society of Therapeutic Radiology and Oncology (ASTRO) Annual Meeting, San Francisco

C. Faculty Development: 2010 2009 Workshop for Small Group Facilitators. Windsor Campus, Schulich School of Medicine & Dentistry Introduction to Using UWO Library Resources Workshop. Windsor Campus, Schulich School of Medicine & Dentistry. Chair of Scientific and Organizing Committee: Developed and coordinated delivery of a CME symposium at the Windsor Campus: “Conquering Malignant Pain & Suffering: New Possibilities”. Windsor, Ontario. Schulich School of Medicine & Dentistry, June 2009. 2008 Enrolment in a Distance Education Certificate Program in Medical Education (PG CertEd), University of Dundee, Scotland, UK. (ongoing) Preparing for the Role of Course Coordinators Workshop, 2 MAINPRO-M1 Credits Teaching Patient Centred Clinical Methods 2.5 MAINPRO-M1 credits Teaching Patient Centred Context: Integration and Application Tutorial Training Session, Schulich School of Medicine, 2.5 MAINPRO-M1 Credtis 2004 Division of Radiation Oncology Annual Retreat, April, London, Ontario

Christopher C. Leighton MD, FRCPC 2003 2000 - 2005

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Radiation Biology Refresher Course, University of Western Ontario UWO Faculty of Epidemiology and Biostatistics MSc Program. Completed MSc Program Course prerequisites (2001-03): Full Semester Courses Principles of Biostatistics Clinical Epidemiology Biostatistics II Occupational Health Analytical Epidemiology Clinical Epidemiology II Design Analysis/ Clinical Trials Grade 91 89 81 94 92 85 83

1999

Complementary Medicine Workshop University of Toronto, Toronto, ON

D. Electronic Continuing Medical Education Programs (Accredited) 2010 Herpes Zoster: prevention and Care of Your Roof! Queens University Faculty of Health Sciences CPD, 1 hour RCPSC MOCERT (Section 1) Issues in the Treatment of Relapsed or Refractory Hodgkin Lympoma: An Expert Interview with Dr. Craig Moskowitz, 0.5 hour RCPSC MOCERT (Section 2) A Practical Guide for the Use of Opioid Therapy for Chronic Non-Cancer Pain. 1 hour RCPSC MOCERT (Section 1) 2009 Osteoarthritis Pain, Queens University Faculty of Health Sciences CPD, 1 hour RCPSC MOCERT (Section 1) Asthma Vignette 1, Schulich School of Medicine & Dentistry, 1 hour RCPSC MOCERT (Section 1) Chronic PPI Therapy – Balancing Risks and Benefits, Schulich School of Medicine & Dentistry, 1 hour RCPSC MOCERT (Section 1) A Fib and the ATHENA Trial – an Appraisal. Canadian Cardiovascular Society, 1 hour

Christopher C. Leighton MD, FRCPC RCPSC MOCERT (Section 1) 20 Medico-legal questions -- Test your knowledge. Canadian Medical Protective Association, 1 hour RPCSC MOCERT (Section 2) Angiogenesis: A new target in cancer treatment. Advancing In. 1 hour RCPSC MOCERT (Section 1) SCHOLARLY AND PROFESSIONAL ACTIVITIES I. Professional Society Memberships: 2011 2008 Canadian Association for Medical Education Canadian Society of Palliative Care Physicians Canadian Pain Society 2003 Canadian Medical Association (CMA)

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Canadian Association of Physicians with Disabilities (CAPD – CMA Affiliate), Ontario Rep. 1998 1996 European Society for Therapeutic Radiology and Oncology (ESTRO) Fellow of the Royal College of Physicians and Surgeons, Division of Medicine American Society of Therapeutic Radiology and Oncology (ASTRO) 1993 College of Physicians and Surgeons of Ontario Canadian Medical Protective Association Ontario Medical Association II. Conference Roles: 2009 Organizer and Chair of the Scientific Committee, “Managing Malignant Pain & Suffering -- New Possibilities”, Schulich School of Medicine & Dentistry, Windsor Campus, June 2009 Royal College of Physicians and Surgeons

2004

Christopher C. Leighton MD, FRCPC

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Radiation Oncology Exam Preparation Course: Lecturer/Leader for Colorectal Carcinoma Session, London 1999 Royal College of Physicians and Surgeons Radiation Oncology Exam Preparation Course: Workshop leader for Central Nervous System Tumors and Lymphoma Sessions, London, ON

III. Consulting and Professional Activities: Erie St. Clair LHIN (Local Health Integration Network) – Physician Lead, Pain Management Working Group Committee Member, July – December 2010. Authored initial draft for a comprehensive and interdisciplinary regional chronic pain program which was funded, to begin by April 2011. Chronic Pain Consultant – Erie St. Clair LHIN Regional Pain Progam. Anticipateprovision of consultative services within a new regional chronic pain program one day per week. Pain & Symptom Management, Supportive Care Program, Department of Oncology: Specialized in the outpatient treatment of malignant opioid-refractory, neuropathic pain syndromes 2006-2010. Independent Contractor Consultant, College of Physicians and Surgeons of Ontario, Complaints and Resolutions Division. Clinical Practice in Gastrointestinal and CNS Oncology 1996-2008: Specialized in the treatment of gastrointestinal tract and central nervous system malignancies. Implementation of IMRT at the Windsor Regional Cancer Centre. Fellowship training (at Princess Margaret Hospital, Toronto) included Head and Neck, Gastrointestinal, and Lymphoma malignancies. IV. Community Service/Innovations in Health Care Delivery: 2010 Written Submission to the Standing Committee on Social Policy -- Bill 101, “An Act to provide for monitoring and dispensing of certain controlled substances” Erie St. Clair LHIN Working Group – Authored Draft of Regional Chronic Pain Program Participated in developing a regional pain program strategy between June – November 2010. 2009 Participant in Windsor Regional Hospital’s

Christopher C. Leighton MD, FRCPC Research Initiative (WHRI) 2007 2006 Colonoscopy wait times audit in Windsor region. Ambulatory Palliative Medicine Clinics at the Windsor and Essex County Hospice/Windsor Regional Cancer Centre (2006-2009) Participant/Organizer UWO Faculty of Medicine Career Fair (Radiation Oncology Booth), Year 2 and 3 Medical Students

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2002

Radio interview on colorectal cancer screening and treatment (30 minutes). 1998 Physician representative, Supportive Care Network, Cancer Care Ontario Region (CCOR)—South Invited to author articles on cancer treatment for local newspaper, The Windsor Star. 1997 Establishment of a Joint Multidisciplinary Neurooncology/Neurosurgical Brain Tumor Clinic at the Hotel-Dieu Hospital, Windsor, Ontario with Dr. Susan Brien.

COMMITTEE MEMBERSHIPS University: 2010-2011 2008-2011 2008-2010 2009-2010 Clinical Methods Course Committeee Introduction to Medicine Course Committee Windsor Program Committee, Schulich School of Medicine, University of Western Ontario Interprofessional Health Care Education Task Force Transition Period Planning Committee 2008-2010 Chair, Year One & Two Windsor Course Coordinators Committee, Schulich School of Medicine Preclerkship Transition Committee, Windsor Program, Schulich School of Medicine

Christopher C. Leighton MD, FRCPC Curriculum Committee, Schulich School of Medicine, University of Western Ontario 2003 PhD Examination Committee (University Examiner), Faculty of Graduate Studies, Medical Biophysics Department University of Western Ontario, Division of Radiation Oncology, Internal Protocol Review Committee University of Western Ontario Ethics Review Board for Health Sciences Research Involving Human Subjects (6 month term) Post-Graduate Radiation Oncology Residency Program Committee, London Regional Cancer Centre

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2001-2005

1999-2000

Faculty: 1999-2003

Departmental: 2004 Chair, Dr. Ed J. Brecevic Memorial Fund Committee, Integrated Cancer Program, London Health Sciences Foundation Library and Education Committee, London Regional Cancer Centre Supportive Care Network, CCOR South, Executive Committee Representative Neuro-Oncology Disease Site Group, Cancer Care Ontario, Practice Guidelines Initiative Windsor Regional Cancer Centre, Library and Education Services Committee COMMITTEE REPORTS Leighton, C and Ng, D. Drafted initial Regional Chronic Pain Management model for an interdisciplinary, regional chronic pain program to serve the Erie-St. Clair LHIN encatchment region. Approved for funding in December 2010 (for April 2011). http://www.eriestclairlhin.on.ca/SearchPage.aspx?searchtext=leighton then click on “07Agenda item 11.4 – Regional Pain Management Clinical Model Nov 11 2010 Final.pdf”.

2000 Past: 1998-1999 1998-1999

Christopher C. Leighton MD, FRCPC

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Leighton, C. Written Submission made to the Standing Committee on Social Policy – Bill 101 “Narcotics Safety and Awareness Act, 2010”, on October 18, 2010. Leighton C. Governance Review of the Undergraduate Medical Windsor Program, Schulich School of Medicine & Dentistry. Presented to External Reviewers, January 2010. Leighton, C. Written and Oral Submission made the to the Standing Committee on Social Policy and Justice, Bill 107 “Human Rights Code Amendment Act, 2006” Leighton, C. “Guidelines for Reporting Radiation Dose Equivalence/Risk from Radiation Exposure”, University of Western Ontario Ethics Review Board for Health Sciences Research Involving Human Subjects, March 2000

Christopher C. Leighton MD, FRCPC

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STUDENT AND RESEARCH TRAINEE SUPERVISION Project/Goal The role of the HPV Vaccine on sexual activity Is Distributed Medical Education effective? Colonoscopy Wait Time Audit in the Erie-St. Clair LHIN Prognostic Factors for Gallbladder Cancer Student Name/Year/Program Successfully Completed Progress Patricia Hizo-Abes, Laura Allen, Moska Hamidi,Richa Sharma, Lisa Gabrielli Melissa Tenbergen, Caitlin Thompson, Megan Holmes, Sylvia Tessier Year 2 students project for Community Health/Ethics Course. In Progress

Year 2 Ethics Project: In Progress Survey among Canadian medical students where distributed learning is established Bonnie Tsang, 3rd year medical Ongoing research project Completed student, Schulich School of with grant from the Medicine, UWO Windsor Regional Cancer Centre Foundation William Tong, 2003-04, Faculty of Medicine, UWO, Year 5 Research Completed. Completed Abstract Presentation at the 2007 GI Cancer Symposium, American Society of Clinical Oncology. Manuscript in progress. Completed extensive Completed patient database and analyses. Presented at the 2004 GI Symposium of the American Society for Clinical Oncology and the UWO Dept. of Oncology Annual Research Day. Received Radiation Oncology Resident Research Award

The importance Dr. Ed Brecevic, 2002-03, of dose Radiation Oncology Resident escalation in PGY-3 Stage II-III rectal cancer

Christopher C. Leighton MD, FRCPC

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CONTRIBUTIONS TO TEACHING AND EDUCATION CURRICULUM DEVELOPMENT AND COURSES TAUGHT 2010 Year One Medicine (Class of 2014), Windsor Campus: Introduction to Medicine, “Getting Comfortable with Palliative and End-Of-Life Care”, 1.5 hour interactive discussion session including 20 minute live patient interview. Introduction to Medicine, “Growing Older Day”, Interactive Panel Discussion (1.5 hours) followed by experiential learning in the community (3 hours) and lunch debriefing session (0.5 hours). See 2009 course for detailed description. Patient Centered Clinical Methods, Year 1: “The Art of Doctoring”. Two-hour interactive lecture and patient interview which introduced the Clinical Methods course. In conjunction with a one hour VC presentation by Dr. Goldszmidt Year Two Medicine (Class of 2013), Windsor Campus Digestion & Nutrition, “Patient-Centered Context: Integration and Applications (PCCIA)” (substituted for 1 session) Respiratory 7 Airways Year 2 Clinical Methods (two 3 hour sessions) 2009 Year One Medicine (Class of 2013), Windsor Campus: Revision of Year 1 and 2 Oncology objectives, assisted Michael Sanatani, UME Oncology Coordinator. Introduction to Medicine, “Patient-Centred Context: Integration and Applications (PCCIA)”. Weekly, 2-hour sessions, throughout 2009-10 academic year. Introduction to Medicine, “Getting Comfortable with Palliative and End of Life Care”. Lecture and interactive discussion session with interprofessional palliative care panel. 1.5 hours. Authored the Week 3 PCCIA module: “Palliative and End-of-Life Care: A Canadian Perspective”, which examines cross-cultural

Christopher C. Leighton MD, FRCPC barriers when counseling families about end-of-life care and explores the unique beliefs of aboriginal persons in this respect.

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Introduction to Medicine Course: Developed and facilitated “Growing Older Day” in Windsor that includes a section titled: “Interprofessional Health Care in Action”. The half-day session includes a lecture from a RN, BSW Discharge Planner and two clinical cases to work through with a physician, nurse, dietician, speech/language pathologist and physiotherapist. It is followed by a “debriefing session” facilitated by me over the lunch period, when students share their learning experiences (5 hours total). Year Two Medicine (Class of 2012), Windsor Campus: Patient-Centred Context: Integration and Applications, Endocrine. (6 two-hour sessions) Gastrointestinal Cancer Review, Year Two Digestion and Nutrition Course. (2 hour interactive lecture) Clinical Methods, Neuroscience Teaching. (9 hours total) 2008 Year One Medicine (Class of 2012), Windsor Campus: Introduction to Medicine, Patient-Centred Context: Integration and Applications, weekly 2 hour sessions throughout academic year. Patient-Centred Year One Clinical Methods, Introduction to Interviewing Skills. (6 three-hour sessions) Patient-Centred Year One Clinical Methods, Introduction to Physical Exam Skills. (6 three-hour sessions) Introduction to Medicine, “Getting Comfortable with Palliative and End of Life Care”, 1.5 hour lecture, student discussion, and interprofessional palliative care panel. Introduction to Medicine, Experiential Learning, Academic Half Day – Elder Care, Windsor Campus. Organized and participated in Windsor Campus Session. Locations: Sandwich Community Health Centre, Windsor Regional Hospital – Metropolitan and Western Campuses. One hour Introductory Lecture on Elder Care with an interdisciplinary panel discussion preceded experiential learning. Revision of Palliative Medicine Clerkship Syllabus: Added

Christopher C. Leighton MD, FRCPC the “SPIKES” method of breaking bad news and use of methylnaltrexone for constipation. 2007

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Introduction of Palliative Medicine into the Core Clerkship Curricula (Schulich School of Medicine, UWO). 1) Comprehensive Palliative Medicine syllabus developed, now included in core oncology curricula in Year 3 Medicine. 2) Clinical training in cancer pain management and palliative medicine commenced for clerks in June 2007, at the Windsor campus of the Schulich School of Medicine, UWO. 3) Ongoing evaluation of curriculum success planned with pre and post clinic day testing. Epidemiology and Critical Appraisal in Oncology, Royal College of Physicians and Surgeons Accredited Seminar Course for Radiation Oncology Residents. Completed 3 sessions. Attendance: 10-15, Total Preparation Time: 8 hrs. Instructor: Christopher Leighton Patient Centred Learning, Year 1 and 2 Undergraduate Medicine Facilitated PCL small group learning sessions (6 two hour classes in each year) Biostatistics in Cancer Research. Royal College of Physicians and Surgeons Accredited Course taught to oncology residents, oncologists, and medical physicists. Six, two-hour lecture/seminar sessions with an assignment and final exam. Novel Syllabus provided. Total Preparation/Course Time: 50+ hrs. Attendance: 20

2004

2002-03

2001

II. CLINICAL ROTATION/SPECIALTY SEMINARS AND CLINICAL SUPERVISION A. Post-graduate Medical Teaching/Rotation Supervision: Supervision and teaching of radiation oncology/medical residents during 1-2 month clinical rotations: Dr. David Want, PGY-5 2001 Dr. Aldo Chan, PGY-1 2001 Dr. Ed Brecevic, PGY-1 2002 Dr. Vinay Lodha, PGY-1 (Path.) 2002 Dr. Tracy Sexton, PGY-1 2002 Dr. Krystyn Lupe, PGY-1 2003 Dr. Karen Chu, PGY-1 2004 Dr. Lauren Lukkas, PGY-1 2004 Dr. J. Bouekhoud, PGY-1 2007

Christopher C. Leighton MD, FRCPC (Nuclear Medicine)

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B. Undergraduate Medical Teaching/Rotation Supervision – Palliative Medicine Jasper Yen, 3rd year Clinical Clerk Chris Chu, 4th year Clinical Clerk William Tong, 4th year Clinical Clerk Stephanie Soo, 3rd year Clinical Clerk Alex Moreno, 3rd year Clinical Clerk Harmon Fong, 3rd year Clinical Clerk Brian Tse, 3rd year Clinical Clerk Michael Pariser, 3rd year Clinical Clerk John Lenehan, 3rd year Clinical Clerk Carolyn Nowry, 3rd year Clinical Clerk Laura Miles, 3rd year Clinical Clerk Olga Li, 3rd year Clinical Clerk Wilfrid Tam, 3rd year Clinical Clerk Sapna Sharma, 3rd year Clinical Clerk Iwona Baron, 3rd year Clinical Clerk Michael Chamberlain, 3rd year Clinical Ck Sarah Edwards, 3rd year Clinical Clerk Zohair Saed, 3rd year Clinical Clerk Michael Bishara, 3rd year Clinical Clerk C. Presentations and Didactic Teaching 2010 Introduction to Medicine – Getting Comfortable with Palliative Care, Year One Undergraduate Medicine, Windsor Program, 1.5 hour interactive session, Videocast to London. “Elder Care Day”, 2 hour interactive session (total) and 2 hours experiential learning. “The Art of Doctoring”, Introduction to Year One Patient Centered Learning, 2 hour interactive session, Windsor Program. 2009 “Gastrointestinal Oncology – An Overview.” 2 hour interactive lecture to Year Two Undergraduate Medicine, Windsor Program. “Getting Comfortable with Palliative and End-of-Life Care” 90 minute interactive session to Year One Undergraduate Medicine Schulich School of Medicine & Dentistry, Videocast to London. 2002 2003 2003 2007 2007 2007 2007 2007 2007 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008

Christopher C. Leighton MD, FRCPC “Growing Older Day”, 1.5 hour interactive session, Year One Undergraduate Medicine, Schulich School of Medicine & Dentistry, Windsor Campus “Growing Older Wrap-up Session”, one-hour interactive session, Schulich School of Medicine & Dentistry, Winsdor Campus

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“Clearing the Fog about the Cannabinoids”, 45 minute lecture, at the Windsor Campus of the Schulich School of Medicine & Dentistry CME event: “Conquering Malignant Pain & Suffering: New Possibilities”. “ Introduction to CME Event: Conquering Malignant Pain & Suffering”, 15 minute lecture, Schulich School of Medicine & Dentistry, Windsor Campus. 2008 “Introduction to Medicine”, Year One Schulich School of Medicine. “Conversations with a Physician: Getting \ Comfortable With Palliative and End-of-Life Care”, 2 hour interactivesession with London and Windsor Campuses. “Dementia and Delirum in 30 minutes.” Year One Medicine Lecture, Windsor Campus, Schulich School of Medicine Elder Care Day Wrap Up: Debriefing of experiential learning session and presentation of Sexuality in the Elderly. Co-presenter, Beth Piet RN, Elder Care Nurse Specialist. 1 hour. “The Pitfalls of Cancer Pain Management, and How to Avoid Them”, Supportive Care Grand Rounds, Windsor Regional Cancer Centre 2004 Royal College of Physicians and Surgeons Radiation Oncology Exam Preparation Course, Colorectal Cancer Seminar Leader 1 hour seminar (4 hour preparation time) Patient Centred Learning Tutorial Leader, Year One Medicine, Winter Session 2004. Eight sessions (2 hours each). 2003 Gastrointestinal Oncology. Session for Radiation Therapy Technology (RTT) Students given at the London Regional Cancer Centre. (90 minute seminar) Oral Examinations, PGY-2 and PGY-3 Radiation Oncology Residents, Dr. E. Brecevic and Dr. A. Chan.

Christopher C. Leighton MD, FRCPC Topic: Radiation Physics and Radiation Biology Preparation Time: 3 hours, Exam Time: 1 hour 2001 2000

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Oral Examinations, PGY-5 Radiation Oncology Resident, Dr. Pamela Leco Radiation Treatment Planning Rounds, Radiation Oncology Residents, Retro-orbital mass Radiation Planning techniques, April. 1 hour seminar (Preparation time 2 hours) Royal College of Physicians and Surgeons Radiation Oncology Exam Preparation Course, January Course Leader, Lymphoma and Neuro-oncology Sessions, University of Western Ontario 1 hour session (4 hour preparation time) Radiation Oncology Residents Lecture, Solitary Plasmacytoma/Multiple Myeloma. 1 hour session. Preparation Time: 1 hour Radiation Oncology Residents Radiation Planning Review Session, Skin Carcinoma, November. 1 hour session Preparation Time: 1 hour Radiation Oncology Residents’ Lecture, Anal Canal Carcinoma. 2 hour session. Preparation Time: 90 minutes Radiation Oncology Residents’ Lecture, Nasopharyngeal Carcinoma. 2 hour session. Preparation Time: 1 hour. Oral Examinations in Radiation Oncology, Radiation Oncology Residents. Two hour exam.

1998 1997

“The Lymphomas”, Continuing Education Program for Allied Health Professionals, Windsor Regional Hospital Research Fellows’ Grand Rounds, Princess Margaret Hospital, “Radiotherapy for Relapsed, Early-Stage Hodgkin’s Disease”, Toronto, Ontario “Delayed Radiotherapy in the Management of Adult Supratentorial Low-Grade Gliomas”, Windsor Regional Cancer Centre Oncology Rounds

1996

Victoria Hospital Residents’ Research Day, Radiation Oncology Division, “Management of Supratentorial Low-Grade Gliomas: The University of Western Ontario Experience.

Christopher C. Leighton MD, FRCPC III. ADDITIONAL ROLES IN EDUCATION 1. PhD. Thesis University Examiner, Medical Biophysics Program Examinations: Candidate: Tim Craig Title: Modeling Geometric Uncertainties in Radiation Therapy, January 2003. 2. Radiation Oncology Residency Selection Committee Interviews 2003 Interviewed 20 candidates over two days 2002 Interviewed 7 candidates in one day 2001 Interviewed 10 candidates in one day. 3. External Governance Review, Windsor Undergraduate Medical Program, January 2010. Interviewed by external reviewers. Written submission provided. 4. Schulich School of MedicineApplicant Interviews, March 6, 2010 Interviewed 4 Schulich School of Medicine applicants. RESEARCH FOCUS Current:

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A. Medical Education: Curriculum Evaluation and Development. 1) My interest is in applying the scientific method to evaluate and improve the undergraduate curriculum. This is a focus of my medical education studies. I have evaluated the attitudes of year 1 students toward interprofessional health education (RIPLS instrument) before and after interdisciplinary sessions provided in the first 6 weeks of medical school. 2) I have developed curriculum for Year One Introduction to Medicine and the Human Development Thread, focusing on interdisciplinary education through interactive panel discussions. Past: A. Colorectal Cancer: i) Completed outcome analyses of patients treated for rectal cancer at the London Regional Cancer Centre. A prognostic index for Stage II-III rectal carcinoma was been devised to predict 4 year overall survival, based on the presence of adverse features. ii) I acted as a mentor for Dr. Ed Brecevic, PGY-3, as we completed an extensive database on patients treated with stage II-III rectal carcinoma at the London Regional Cancer Centre. Initial analyses led to presentations at the Annual Meetings of the Canadian Association of Radiation Oncology, and the American Society for Clinical Oncology/GI Cancer Symposium. B. Central Nervous System Tumors: A comprehensive database of patients with lowgrade glioma was completed in 1995. Subsequent outcomes analyses by me and my Department of Oncology colleagues have led to 9 publications (3 first-authored) and numerous presentations at international meetings. I have since completed a meta-analysis of radiation therapy trials in this area. This was presented at the 2003 Meeting of the

Christopher C. Leighton MD, FRCPC

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American Society of Clinical Oncology and at the Global Temozolomide Researchers Meeting, Porto, Portugal 2004. Continued collaboration led to a first authored publication in 2007 reviewing the role of radiation dose and surgical resection in outcome in Low-Grade Gliomas. C. Gallbladder Cancer: I have acted as a mentor for William Tong, a year 4 UWO medical student, who has completed a substantial review of this rare gastrointestinal neoplasm. An abstract was presented at the 2007 ASCO GI Cancer Symposium. Our work validated the UICC Staging system for Gallbladder Carcinoma. William is presently a Radiation Oncology Resident at McGill University. He will complete a manuscript. RESEARCH FUNDING/CLINICAL TRIAL GRANTS
2004 A RANDOMIZED, DOUBLE BLIND, PLACEBO-CONTROLLED PHASE III STUDY TO DETERMINE THE EFFICACY OF SANDOSTATIN LAR® DEPOT (OCTREOTIDE ACETATE) IN PREVENTING OR REDUCING THE SEVERITY OF CHEMORADIATION-INDUCED DIARRHEA IN PATIENTS WITH ANAL OR RECTAL CANCER (RTOG 0315) CENTRE PRINCIPAL INVESTIGATOR: CHRISTOPHER LEIGHTON MD CO-INVESTIGATORS: BARBARA FISHER MD, FRANCISCO PERERA MD GRANTING AGENCY: RADIATION THERAPY ONCOLOGY GROUP (RTOG) GRANT: $2000 USD/PATIENT ENROLLED ESTIMATED ENROLMENT: 20-25 PATIENTS CENTRE WIDE ESTIMATED TOTAL AMOUNT: $40,000 – 50,000 ACTIVATED: OPENED TO ACCRURAL IN SPRING 2004, CLOSED FEBRUARY 2006. DR. FISHER BECAME PRINCIPLE INVESTIGATOR IN 2005. 2003 RANDOMIZED PHASE II TRIAL OF PREOPERATIVE COMBINED MODALITY CHEMORADIATION FOR DISTAL RECTAL CANCER (RTOG 0012) CENTRE PRINCIPAL INVESTIGATOR: CHRISTOPHER LEIGHTON MD COINVESTIGATORS: BARBARA FISHER MD, FRANCISCO PERERA MD GRANTING AGENCY: RADIATION THERAPY ONCOLOGY GROUP (RTOG) NB: Trial closed the same month it was approved by the UWO ERB. 2002 DILTIAZEM AS A RADIATION SENSITIZER FOR PATIENTS RECEIVING RADIOTHERAPY FOR BRAIN METASTASIS STUDY AUTHOR AND PRINCIPAL INVESTIGATOR: CHRISTOPHER LEIGHTON MD

Christopher C. Leighton MD, FRCPC

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CO-INVESTIGATOR:

BARBARA FISHER MD

OPERATING GRANT: Integrated Cancer Program/CCRP Funded Centre Trial GRANT: $1500 ACCRUAL TO DATE: 9 patients EXPECTED COMPLETION: unknown AMENDMENT: To include PET imaging to evaluate tumor perfusion prediltiazem, with diltiazem, and following RT + diltiazem. PRESENT STATUS: INACTIVE PET IMAGING INVESTIGATOR: TING-IM LEE PHD (ROBARTS IMAGING)

PUBLICATIONS: A. Articles in Peer Reviewed Journals: Leighton C. Be careful about timelines. Print publication: CMAJ 2010; 181(1); 63. Electronic Publication (with entire submission): CMAJ 2010;181(11):868.http://www.cmaj.ca/cgi/reprint/182/1/63. Leighton C. In response to: “A New Direction for Undergraduate Medical Education”, CMAJ 2008;178: 11. Electronic publication: 1 April 2008. http://www.cmaj.ca/cgi/letters/178/1/11#18989. Leighton C, Fisher B, Macdonald D, Stitt L, Bauman G, Cairncross JG. The dose– volume interaction in adult supratentorial low-grade glioma: higher radiation dose is beneficial among patients with partial resection. J. Neuro-Oncology 2007;82:156-70.
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Leighton, C.; Shum, D. “Osteoclastic Giant Cell Tumor of the Pancreas: A Case Report and Literature Review.” Am J Clin Oncol 2001; 24:77-81. Republished in the Chronical of Cancer Therapy, Winter 2003. Laperriere N, Zuraw L, Cairncross G, The Cancer Care Ontario Practice Guidelines Initiative Neuro-Oncology Disease Site Group. Radiotherapy for newly diagnosed malignant glioma in adults: a systematic review. Radiotherapy & Oncology 2002;64:25973. Tai P, Van Dyk J, Battista J, Yu E, Stitt L, Tonita J, Agboola O, Brierley J, Dar R, Leighton C, Malone S, Strang B, Truong P, Videtic G, Wong CS, Wong R, Youssef Y. Improving the Consistency in Cervical Esophageal Target Volume Definition by Special Training. Int J Radiat Oncol Biol Phys 2002 Jul 1;53(3):766-74. Fisher, B.; Naumova, E; Leighton, C.; Kerkvliet, N.; Naumova, G.; Chambers, A; Fortin, D; Macdonald, D.; Cairncross, J.; Bauman, G.; Stitt, L. Ki-67 – A Prognostic

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Unsolicited republication requested by editor

Christopher C. Leighton MD, FRCPC Factor for Low-Grade Glioma? Int J Radiat Oncol Biol Phys 2002 Mar 15;52(4):9961001. Fisher, BJ; Leighton, CC; Vujovic, O; Macdonald, DR; Stitt, L. Results of a Policy of Surveillance Alone after Surgical Management of Pediatric Low-Grade Glioma. Int J Radiat Oncol Biol Phys 2001;51:704-710.

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Leighton, C.; Shum, D. Osteoclastic Giant Cell Tumor of the Pancreas: A Case Report and Literature Review. Am J Clin Oncol 2001; 24: 77-81. Leighton, C;Fisher, B; Perera, F. Acute Radiation Proctitis. Lancet 2001; 357: 306-307.
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Leighton, C.Author Update: “Supratentorial low-grade glioma in adults: an analysis of prognostic factors and timing of radiation. J Clin Oncol 1997:15; 1294-1301”,Journal of Clinical Oncology Classic Papers and Current Comments: Highlights of Neurologic Cancer Research,2001 Vol 5, No 2: 290-298. Bauman, G.; Lote, K.; Larson, D.; Stalpers, L; Leighton, C.; Fisher, B.; Wara, W.; Macdonald, D.; Stitt, L.; Cairncross, J. Pretreatment Factors Predict Overall Survival For Patients With Low-Grade Glioma: A Recursive Partitioning Analysis. Int J Radiat Oncol Biol Phys 45: 923-929, 1999. Bauman, G.; Pahapill, P.; Macdonald, D.; Fisher, B.; Leighton, C.; Cairncross, J. Low Grade Glioma: Measuring Radiographic Response to Radiotherapy. Can J Neurol Sci 26:18-22, 1999. Fisher, B.; Bauman, G.; Leighton, C.; Macdonald, D.; Cairncross, J.; Stitt, L. Pediatric Low-Grade Gliomas: Tumor Volume Response to Radiation. J Neurosurg 88:969-974, 1998. Fisher, B.; Bauman, G.; Leighton, C.; Stitt, L.; Cairncross, J.; Macdonald, D. Lowgrade Gliomas in Children: Tumor Volume Response to Radiation. Neurosurg Focus 4(4):1-10, 1998. Leighton, C.; Fisher, B.; Bauman, G.; Depiero, S.; Stitt, L.; Macdonald, D.; Cairncross, J. Supratentorial Low-Grade Glioma in Adults: An Analysis of Prognostic Factors and Timing of Radiation. J Clin Oncol 1997; 15:1294-1301. Leighton, C.; Cairncross, J. Low-grade glioma--the Europeans are Winning! J Clin Oncol 1997;15: 2761. Leighton, C.; Springer, C. Bone Metastasis: Radiotherapy for Effective Palliation of Pain. University of Toronto Medical Journal, Vol. 68, No. 2, 1991.

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Republication and author update as requested by editor, Journal of Clinical Oncology

Christopher C. Leighton MD, FRCPC B. Abstracts Accepted for Presentation (Peer reviewed)

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Leighton, C; Wong, T; Perera, F; Fisher B; Stitt L; Engel, J. T stage predicts survival in gallbladder carcinoma. Annual 2007 GI Cancer Symposium of the American Society of Clinical Oncology. Fisher B, Alibhai Z, Perera F, Leighton, C, Kocha W, Vincent V, Stitt L. Preoperative preradiation chemotherapy for locally advanced unresectable rectal cancer. Presented at the 2005 GI Cancer Symposium of the American Society for Clinical Oncology. Leighton C, Brecevic E, Perera F, Fisher B, Stitt L, Vincent M, Kerr, I, Dingle B, Logan D. The UWO Prognostic Index for Patients with Stage II-III rectal carcinoma treated with chemoradiation. Presented at the European Society for Therapeutic Radiology and Oncology Annual Meeting, September 2004. Leighton, C; Brecevic, E; Stitt, L; Perera, F; Fisher, B; Kocha, W; Kerr, I; Engel, J; Taylor, B; Kuruvilla, P. F; Vincent. A prognostic index for stage II-III rectal cancer patients receiving post-operative adjuvant radiotherapy and chemotherapy. University of Western Ontario Department of Oncology Research and Awards Day, May 2004, London, Ontario Brecevic, E; Leighton C; Fisher, B; Stitt, L; Whiston, F; Perera, M; Kocha, W; Kerr, I; Engel, J; Taylor, B; Kuruvilla, P. F; Vincent. Does radiation dose escalation improve outcome in stage II-III rectal cancer? University of Western Ontario Department of Oncology Research and Awards Day, May 2004, London, Ontario. Brecevic, E; Leighton C; Fisher, B; Stitt, L; Whiston, F; Perera, M; Kocha, W; Kerr, I; Engel, J; Taylor, B; Kuruvilla, P. F; Vincent. Does radiation dose escalation improve outcome in stage II-III rectal cancer? Presented at the American Society for Clinical Oncology GI Cancer Symposium, San Francisco, January 2004, (abstr 254). Brecevic, E; Leighton, C;Fisher, B; Stitt, L; Whiston, F; Perera, M; Kocha, W; Kerr, I; Engel, J; Taylor, B; Kuruvilla, P. F; Vincent. Does radiation dose escalation improve outcome in rectal cancer? Presented at the annual meeting of the Canadian Association of Radiation Oncologists. Radioth Oncol 2003; 69 (Suppl 1): Abstr 64, S16. Leighton, C; A Meta-analysis of Radiotherapy for Adult Low-Grade Glioma. Presented at the 2003 Annual Meeting of the American Society of Clinical Oncology (ASCO), Chicago, IL. Proc Am Soc Clin Oncol 2003; 22:111 (Abstr 442). Leighton, C; Fisher, B; Stitt, L; Macdonald, D; Bauman, G; and Cairncross, JG. The dose-volume interaction in adult supratentorial low-grade glioma: Higher radiation dose is beneficial among patients with partial resection. Presented at the European Conference on Clinical Oncology (ESTRO division), Lisbon, Portugal. Eur J Cancer, 2001; 37(Suppl. 6): 23 (Abst 75).

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Leighton, C; Fisher, B; Stitt, L; Macdonald, D; Cairncross, J; The Dose-Volume Relationship in Poor Risk Low-Grade Glioma: Is Higher Dose Radiation Beneficial? Presented at the American Society of Clinical Oncology Annual Meeting, San Francisco, CA. Proc Amer Soc Clin Oncol, 2001; 20-I: 59a (Abstr 233). Tai, P; Van Dyk, J; Battista, J; Stitt, L; Agboola, O; Brierly, J; Dar, R; Leighton, C;Malone, S; Strang, B; Truong, P; Wong, C; Videtic, G; Youssef, Y. Improving the Consistency in Esophageal Target Volume Delineation By Special Training. Presented at the annual meeting of the British Institute of Radiology, University College of Ripon and York, UK, 2001. Fisher B, Naumova E, Kerkvliet N, Naumov G, Chambers A, Fortin D, Leighton C, Macdonald D, Cairncross J, Bauman G, Stitt L. Is Ki-67 a prognostic factor in lowgrade glioma? Int J Radiat Oncol Biol Phys2000 Jan 1;48; (3 Suppl 1):201. Presented at the American Society for Therapeutic Radiology and Oncology, Boston, MA, 2000. Fisher, B; Leighton, C; Naumova, E et al. Pediatric Low-Grade Glioma: Delayed Radiation Treatment. Presented at the Annual Pediatric Neuro-oncology Meeting, San Francisco, 2000. Leighton, C; Fisher, B; Vujovic, O; Macdonald, D; Stitt, L. Surveillance Alone after Surgical Management of Pediatric Low Grade Glioma. Neuro-oncology 2000; 2(3), Abstr. 20: 200. Presented at the Canadian Neuro-oncology 9th Biennial Meeting, Vancouver, British Columbia, 2000. Fisher, B; Naumova, E; Kerkuliet, N; Chambers, A; Fortin, D; Leighton, C; Macdonald, D; Cairncross, J; Bauman, G; Stitt, L. Ki-67—A Prognostic Factor For Low-Grade Glioma? Neuro-oncology 2000; 2(3), Abst#9: 197-198. Presented at the Canadian Neurooncology 9th Biennial Meeting, Vancouver, British Columbia, 2000. Bauman, G; Lote, K; Larson, D; Stalpers, L; Leighton, C; Fisher, B; Wara, W; Macdonald, D; Stitt, L; Cairncross, J. Pretreatment Factors Predict Overall Survival For Patients With Low-Grade Glioma: A Recursive Partitioning Analysis. Presented at ASTRO, Phoenix, AZ, 1999. Fisher, B; Bauman, G; Leighton, C; Stitt, L; Cairncross, G. Pediatric Low Grade Gliomas: Volume Response to Radiation. Canadian Neuro-oncology 8th Biennial Meeting, Niagara-on-the Lake, Ontario, 1998. Bauman, G; Cairncross, J; Macdonald, D; Fisher, B; Leighton, C; Stalpers, L.; Larson, D; Wara, W; Stitt, L. Low Grade Glioma: Recursive Partitioning Analysis of 224 Patients. Canadian Neuro-oncology 8th Biennial Meeting, Niagara-on-the Lake, Ontario, 1998. Bauman, G; Stalpers, L; Larson, D; Wara, W; Fisher, B; Macdonald, D; Stitt, L;

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Leighton, C; Cairncross, J. Low Grade Glioma: Recursive Partitioning Analysis of 224 Patients. Proc Am Soc Clin Oncol -- J Clin Oncol, 1988; 17: #1500: 389. Presented at ASCO, Los Angeles, 1998. Bauman, G; Fisher, B; Leighton, C; Pahapill, P.; Macdonald, D. Low Grade Glioma: A Quantitative and Qualitative Analysis of Response to Radiotherapy. Canadian Neurooncology 8th Biennial Meeting, Niagara-on-the Lake, 1998. Leighton, C.; Fisher, B.; Bauman, G.; Depiero, S.; Stitt, L; Macdonald, D.; Cairncross, J. Delayed Radiotherapy in The Management of Supratentorial Low-Grade Glioma: Importance of Histology, Not Timing of Radiation. Radiother Oncol 40 (Suppl. 1): S179, 1996. Presented at the annual meeting of the European Society for Therapeutic Radiology and Oncology, Vienna, Austria, 1996. Leighton, C.; Fisher, B.; Bauman, G.; Depiero, S.; Stitt, L; Macdonald, D.; Cairncross, J. Delayed Radiotherapy in the Management of Supratentorial Low-Grade Glioma. Presented at the Royal College of Physicians and Surgeons Annual Meeting, Halifax, Nova Scotia, 1996. Pahapill, P.; Bauman, G.; Fisher, B.; Leighton, C.; Macdonald, D.; Cairncross, J. Low Grade Glioma - Extent and Timing of Response to Radiotherapy. Int J Radiat Oncol Biol Phys 36 (Suppl.): 292; 1996. Presented at the annual meeting of the American Society for Therapeutic Radiology and Oncology, Los Angeles, California, 1996. Pahapill, P.; Bauman, G.; Fisher, B.; Leighton, C.; Macdonald, D.; Cairncross, J. Low Grade Glioma--Extent and Timing of Response to Radiotherapy. Abstract: 7th Canadian Neuro-Oncology Meeting, 1996, Montreal, Quebec. Leighton C, and Springer C. Pain and Quality of Life Assessments in Patients Receiving Palliative Radiotherapy for Bone Metastasis. Abstract: University of Toronto Medical Student Research Day, 1991. C. Non-Peer Reviewed Publications Leighton, C. Letter to the Editor: “OMA Policy Paper on Patient-Centred Care”, Ontario Medical Review 2010; 77(9):8. D. Unpublished Manuscripts Leighton C. Occupational Carcinogenesis Among Rubber Manufacturers – A Schema for Minimizing Risk. [Manuscript required for Biostatistics and Epidemiology Diploma studies). Leighton, C. “The Child with a Brain Tumor: Challenges for the Family”. Clinical Workshop in Neurologic and Behavioral Paediatrics, The Hospital for Sick Children. March, 1991 [unpublished]

Christopher C. Leighton MD, FRCPC D. Submitted Abstracts

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Brecevic, E; Leighton C; Fisher, B; Stitt, L; Whiston, F; Perera, M; Kocha, W; Kerr, I; Engel, J; Taylor, B; Kuruvilla, P. F; Vincent. Does radiation dose escalation improve outcome in stage II-III rectal cancer? Submitted to the American Society for Therapeutic Radiology and Oncology Annual Meeting, October 2004. E. Solicited Newspaper Articles: “Advances in the treatment of brain tumors”, The Windsor Star, March 19, 1998. “Clinical Trials in Cancer Treatment”, The Windsor Star, February 18, 1999. INVITED LECTURES/SYMPOSIA 2011 2010 2007 2004 Schulich Medicine Health Lecture Series: “Chronic Pain: The Silent Epidemic Among Us” Regional Task Force: Breaking Barriers in Breakthrough Cancer Pain Consensus Conference “Advanced colorectal cancer: Psychosocial Issues”, Ontario Association of Medical Radiological Technologists Annual Meeting. Temozolomide Global Investigators Meeting, Oporto, Portugal, “A Meta-Analysis of Radiotherapy for Low Grade Glioma”, (D. Macdonald, Neuro-oncology UWO, presented talk in my absence). Royal College of Physician and Surgeons, Radiation Oncology Exam Preparation Course, Colorectal Cancer Lecture. 2002 Royal College of Physicians and Surgeons, National Radiation Oncology Residency Exam Preparation Course, Central Nervous System Tumor Session.

MEDIA INTERVIEWS “Gastrointestinal Cancer”, 30 minute interview with Dr. Fred Sexton, local London FM1290 radio station host, 2001