HAAD Poison & Drug Information Center ANTIDOTE CHART

Antidote Black widow spider antiserum Atropine sulfate

Indications Black widow spider envenomations Alpha-2 agonists, antimyesthenic agents, bradyarrhythmia-producing agents, cholinergic agonists, muscarine-containing mushrooms, nerve agents, organophosphate and carbamate insecticides food-borne botulism, wound, or interstinal colonization in children or adults( not recommended for infant botulism) Medications causing neuroleptic malignant syndrome Lead, zinc salts poisoning

Botulinum Antitoxin

Bromocriptine mesylate Calcium disodium EDTA Calcium gluconate gel Calcium gluconate INJ

Hydrofluoric acid skin exposure Calcium channel blockers, fluoride salts, hyperkalemia (not digoxin-induced), hypermagnesemia Cyanide antidote kit Cyanide poisoining Cyproheptadine Serotonin syndrome Dantrolene sodium Malignant hyperpyrexia or muscular rigidity Deferoxamine mesylate Iron poisoning Diazepam Digoxin immune Fab Chloroquine and related antimalarial drugs Cardiac glycoside-containing plant ,digitoxin, digoxin Dimercaprol (BAL) Arsenic, copper, gold, lead, lewisite, mercury Diphenhydramine HCL Drug-induced extrapyramidal symptoms Ethanol Ethylene glycol, methanol Flumazenil Benzodiazepines poisoning Folinic acid Methanol, methotrexate, trimetrexate, (Leucovorin Calcium) pyrimethamine, trimethoprim Fomepizole Ethylene glycol, methanol
Glucagon Beta blockers, calcium channel blockers HAAD-PDIC 2008-2009 Page 1

imidazoline decongestants Octreotide acetate Sulfonylurea hypoglycemic agents Phentolamine mesylate Catecholamine extravasation. atropine and other anticholinergic.HAAD Poison & Drug Information Center ANTIDOTE CHART Insulin (Reglular Insulin) L-Carnitine Beta blockers. Low-Molecular -Weight heparin (LMWH) Prussian blue Radioactive cesium (Cs-137). Ethylene glycol Expert advice regarding use of antidotes is available from the PDIC Call us at 800 424 Adapted From Olson. intradigital epinephrine injection Physostigmine Anticholinergic alkaloid-containing plants. Note: List is not all-inclusive but reflects agents used more exclusively as antidotes or antidotal agents used infrequently HAAD-PDIC 2008-2009 Page 2 . Serum Alkalinization. 5th Edition. long-acting K1) anticoagulant rodenticides .alpha-2 agonists. encephalopathy. KR (Ed): Poisoning & Drug Overdose. Urine Alkalinization: Thiamine Ethanol. intrathecal baclofen Phytonadione (vitamin Coumarin and Indandione derivatives. liver failure) Methylene blue Methemoglobin N-Acetylcysteine Acetaminophen. and non-radioactive thallium Pyrdoxine Isoniazide. Adjunct to therapy for ethylene glycol intoxication. Calcium channel blockers Valproic acid (hyperammonemia. carbon tetrachloride. Hyperkalemia.warfarin Potassium iodide Prevents thyroid uptake of radioactive iodine tablet Pralidoxime chloride Organophosphate poisning Protamine sulfate Heparin. radioactive thallium (Tl-201). salicylate antihistamines. Scorpion Anti-serum Scorpion Sting Snake Antivenom Snakes bites Sodium bicarbonate Chlorine gas. other hepatotoxins Naloxone Opioids.

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