FREE QUESTIONS HERE! 1) A 35-year-old man has wrist drop of his right hand.

Examination reveals a small area of sensory loss on the dorsum of the hand. Which of the following nerves is likely to be involved? 1 ) Median nerve 2 ) Ulnar nerve 3 ) Long thoracic nerve 4 ) Radial nerve 5 ) T1 nerve root ANSWER : 2 2) Osteomalacia may be expected in 1 ) Sarcoidosis 2 ) Auto-immune adrenalitis 3 ) Pseudo-hypoparathyroidism 4 ) Pernicious anaemia 5 ) Mercury poisoning ANSWER : 5 3) Which of the following is NOT true with regard to the radiological appearance of a chest X-ray? 1 ) Consolidation of the right middle lobe will obliterate the right atrial shadow in the PA view 2 ) Consolidation of the right apical lobe will extend to the horizontal fissure in the PA view 3 ) Consolidation of the right anterior segment of the right middle lobe will extend to the right transverse fissure and the right hilum in PA view 4 ) A consolidation of the lingular lobe will obliterate the aortic knuckle and pulmonary trunk in the PA view 5 ) A consolidation of the left lower lobe will elevate the left hemidiaphragm ANSWER : 5 4) Primary hyperparathyroidism may occur in association with the following conditions 1 ) Chronic renal failure 1

2 3 4 5 ) ) ) ) Vitamin D deficiency Gastrinoma Autoimmune polyendocrine syndrome Sjogren's syndrome ANSWER: 3 5) Low uptake of 123I on the thyroid uptake scan would be an expected finding in: 1 ) A solitary toxic nodule 2 ) A multi-nodular toxic goitre 3 ) Amiodarone induced thyrotoxicosis type 1 4 ) DeQuervain's thyroiditis 5 ) Graves' thyrotoxicosis ANSWER : 4 6) Which of the following is typically found in Pendred's syndrome 1 ) Mental retardation 2 ) Sensorineural deafness 3 ) Thyroid agenesis 4 ) Thyrotoxicosis 5 ) Cataract ANSWER : 2 7) Which of the following antibodies are typically found in auto-immune adrenalitis (Addison's disease) 1 ) Anti-rho antibody 2 ) Anti-peroxidase antibody 3 ) Anti-21hydroxylase antibody 4 ) Anti-nuclear antibody 5 ) Anti-tryptophan hydroxylase antibody ANSWER: 3 Which of the following may be responsible for a hypokalaemic hypertension 1 ) Non-classical congenital adrenal hyperplasia 2 ) Barter's syndrome 2 .

3 ) Diabetic nephropathy 4 ) Liddle's syndrome 5 ) Type IV renal tubular acidosis ANSWER: 4 9) Which of the following is a feature of Cushing's syndrome? 1 ) Fibrous dysplasia 2 ) Vertebral collapse 3 ) Calcium pyrophosphate arthropathy 4 ) Osteomalacia 5 ) Osteoarthritis ANSWER: 2 10) Which of the following is a likely presenting feature of Cushing's syndrome 1 ) Lichen planus 2 ) Mononeuritis multiplex 3 ) Polymyositis 4 ) Necrosis of the femoral head 5 ) Diabetes insipidus ANSWER: 4 1) Which of the following techniques would be most useful in the differential diagnosis between ectopic Cushing's syndrome and pituitary dependent Cushing's disease. 1 ) Urine free cortisol 2 ) High dose Dexamethasone suppression test 3 ) ACTH concentrations 4 ) Inferior petrosal sinus sampling 5 ) CRF test ASWER: 4 2) A chromophobe adenoma of the pituitary would be expected in which of the following 1 ) Cushing's disease 3 .

3 ) Suppression of GH below 2 mU/l (1.2 3 4 5 ) ) ) ) Acromegaly Non-functioning pituitary tumour TSH secreting tumour Prolactinoma ANSWER:3 3) Adult growth hormone deficiency is confirmed by: 1 ) A low IGF-1 concentration 2 ) An undetectable random Growth hormone concentration. Which of the following diagnoses is least likely. Blood tests show a Bilirubin of 40 µmol/l the other LFT's are completely normal.3 microg/l) with an oral glucose tolerance test 4 ) A peak growth hormone concentration of 6 mU/l (2 microg/l) with insulin induced hypoglycaemia 5 ) A low IGF binding protein-3 (IGFBP3) concentration ANSWER:4 4) A 30 year old caucasian male presents with a six month history of weight loss. abdominal pain. On examination you note finger clubbing. 1 ) Crohn's disease 2 ) Ulcerative colitis 3 ) Coeliac disease 4 ) Whipple's disease 5 ) Ileo-caecal TB ANSWER: 5 5) A 26 year old presents in the first trimester of her first pregnancy (six weeks gestation) for an ante-natal check. and diarrhoea. she feels well. The most likely diagnosis is: 1 ) Gilbert's syndrome 2 ) Primary biliary cirrhosis 3 ) Primary sclerosing cholangitis 4 ) Dubin-Johnson syndrome 5 ) Cholestasis of pregnancy ANSWER: 1 4 .

What is the likely diagnosis? 1 ) adenocarcinoma 2 ) alveolar cell carcinoma 3 ) large cell carcinoma 4 ) small cell carcinoma 5 ) squamous cell carcinoma ANSWER: 5 Oral therapy with which of the following may cause galactorrhoea? 1 ) Bromocriptine 2 ) Cabergoline 3 ) Spironolactone 4 ) Cimetidine 5 ) Domperidone ANSWER: 5 A 75-year-old man with squamous cell carcinoma is thought to have resectable disease. 1 ) Digoxin 2 ) ACE inhibitor 3 ) Salbutamol 4 ) Ranitidine 5 ) Spironolactone ANSWER: 3 7) A 65-year-old man. He recieves frequent nebulised salbutamol and IV digoxin loading. with a history of smoking. congestive heart failure. presents with chronic cough. His Chest X-Ray shows a cavitating lesion. his regular medications are continued.8 mmol/l. Which of his medications is most likely to have caused this abnormality. and peptic ulcer disease is admitted with bronchospasm and rapid atrial fibrillation. Which of the following would be a contraindication to surgery? 1 ) clubbing 2 ) FEV1 of 0. haemoptysis and weight loss. 24 hours after admission his serum potassium is noted to be 2.75 L 3 ) his age of 75 years 5 .6) An elderly man with a history of asthma.

A particular molecule that is produced in the nucleus initiates protein synthesis. This molecule matures in the cytoplasm and binds to the ribosome. HALF MARK FOR ANSWER 4 9) A 62-year-old lady is suffering from pain and stiffness of her shoulders and difficulty getting out of a chair.4 ) pleural effusion 5 ) Syndrome of Inappropriate ADH ANSWER: 2 . This molecule is 1 ) messenger RNA 2 ) ribosomal RNA 3 ) RNA nucleotide 4 ) RNA polymerase 5 ) transfer RNA ANSWER: 1 6 . Which of the following would support a diagnosis of polymyalgia rheumatica? 1 ) ankle stiffness 2 ) low grade fever 3 ) muscle tenderness 4 ) proximal muscle weakness 5 ) weight gain ANSWER : 2 10) Protein synthesis occurs within cells.

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