This action might not be possible to undo. Are you sure you want to continue?
into the body (e.g the rectum); the base dissolves gradually at body temperature, releasing the drug.” (Kozier, Erb, Berman, & Snyder, 2004) “Solid, cone-shaped, medicated substances inserted into the rectum, vagina, or urethra.” (Kozier, Erb, Berman, & Snyder, 2004)
“A drug delivery system that is inserted into the rectum (rectal suppository), vagina (vaginal suppository) or urethra (urethral suppository), where it dissolves. They are used to deliver both systemically-acting and locally-acting medications. The alternative term for delivery of medicine via such routes is pharmaceutical pessary. The general principle is that the suppository is inserted as a solid, and will dissolve inside the body to deliver the medicine.” (Suppository)
“An easily fusible medicated mass to be introduced into a body orifice, as the rectum, urethra, or vagina” (Dorland's Medical Dictionary for Health Consumers, 2007) “A small plug of medication designed to melt at body temperature within a body cavity other than the mouth, especially the rectum or vagina.” (The American Heritage Medical Dictionary, 2007) “A medicinal substance that slowly dissolves after being inserted into the rectum (or other body cavity).” (Gale Encyclopedia of Medicine, 2008) “An easily melted medicated mass for insertion into the rectum, urethra, or vagina. Theobroma oil, glycerinated gelatin, and high-molecular-weight polyethylene glycols are common vehicles for drugs in suppositories that are cone- or spindle-shaped for insertion into the rectum, globular or egg-shaped for use in the vagina, and pencil-shaped for insertion into the urethra. Drugs administered by rectal suppository are absorbed systemically, and this route is especially useful in babies, in uncooperative patients, and in cases of vomiting or certain digestive disorders.” (Mosby's Medical Dictionary, 8th edition, 2009) “An easily fusible medicated mass for introduction into the rectum, urethra, or vagina.” (Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition., 2003) “A solid form of medication of various shapes which, after insertion in the rectum, vagina, or urethra, dissolves and is absorbed into the blood Vehicles Cocoa butter, polyethylene glycol Drugs Aspirin, barbital, chloral hydrate, phenobarbital, procaine, quinine, resorcinol.” (Mc Graw-Hill Concise Dictionary of Modern Medicine, 2002) Suppository (Rectal) - Insertion of medications into the rectum in the form of suppositories is a frequent practice. Rectal administration is a convenient and safe method of giving certain medications.
(Kozier. insert the suppository beyond the internal sphincter (i. Assist the client to a left lateral position. Rectal suppositories are thought to provide higher bloodstream levels (titers) of medication because the venous blood from the lower rectum is not transported through the liver. Insert the suppository gently into the anal canal. The drug is released at a slow but steady rate. along the rectal wall using the gloved index finger. 2004) .e. Put on a glove on the hand used to insert the suppository. Lubricate the gloved index finger. Disadvantages • • • • • Administration: • • • • • Ask the client to remain in the left lateral or supine position for at least 5 minutes to help retain the suppository. Fold back the top bedclothes to expose the buttocks. Press the client’s buttock together for a few minutes. rounded end first (or according to manufacturer’s instructions). Encourage the client to relax by breathing through the mouth. Berman. Bioavailability is variable. The suppository should be retained for at least 30 to 40 minutes or according to manufacturer’s instructions. & Snyder. or see manufacturer’s instructions. 10 cm [4 in. It is advantageous when the medication has an objectionable taste or odor. with the upper leg flexed.]) Avoid embedding the suppository in feces in order for the suppository to be absorbed effectively. For an adult. Erb. Unwrap the suppository and lubricate the smooth rounded end. The rounded end is usually inserted first and lubricant reduces irritation of the mucosa.Advantages • • • • It avoids irritation of the upper gastrointestinal tract in clients who encounter this problem. This usually relaxes the external anal sphincter.
There is the potential of long term drug absorption with various intrauterine devices. The dose can be retrieved if necessary 3. 2. There is less drug degradation via this route of administration compared to oral administration 2.125 mm in length . feminine hygiene antiseptics.Suppository (Vaginal) .To treat gynecological ailments .They are cylindrical in shape.Employed as contraceptives.5 grams. Avoidance of oral and parenteral routes thus less gastrointestinal irritation – Avoid first pass metabolism – Protect drug from harsh conditions in stomach – Drug causes nausea and vomiting . Suppository (Urethral) . Administration. . or to restore the vaginal mucosaThe suppositories are usually globular. Disadvantages: 1. 3 .6 mm in diameter and vary in length according to gender. or cone-shaped and weigh between 3 . Because suppositories are generally used at bedtime and can be messy if the formulation is an oleaginous base. vaginal itching and vaginal dryness. patients should wear a sanitary napkin to protect nightwear and bed linens. Advantages: 1.70 mm in length Male: 50 . Precautions: May cause vaginal burning. Advantages: 1." and is 1.The one commercially available urethral suppository is actually marketed as a "pellet. oviform. bacterial antibiotics.Urethral suppositories are unusual and may not be encountered in a compounding practice.4 mm in diameter and 3 or 6 mm in length depending on strength. There is tendency of some dosage forms to be expelled after insertion into the vagina. It leads to variable absorption since the vagina is a physiologically and anatomically dynamic organ that causes pH and membrane permeability to change over time. Vaginal suppositories are inserted high in the vaginal tract with the aid of a special applicator. Patients should be instructed to quickly dip the suppository in water before insertion. Female: 25 .
Patient suffering from severe vomiting .367-370. Retrieved June 2011. El-Hawi.Can be targeted delivery system 2. the total amount of drug must be given will be irritating.35. The most common side effects are pain and minor discomfort in the penis and perineum and dizziness. . Ann. Erb. Process and Practice). Miller-Keane Encyclopedia and Dictionary of Medicine. (2004). Dorland's Medical Dictionary for Health Consumers. Houghton Mifflin Company. facilitating smooth muscle relaxation and thereby helping to obtain and maintain and erection. K. In some cases. Nursing.4.org/wiki/Suppository The American Heritage Medical Dictionary. Berman. The patient helps the suppository dissolve by rubbing the penis. Elsevier. Suppository. No. 8th edition. Mosby's Medical Dictionary. (n. T. A. and Allied Health. Bradshaw. from Wikipedia: http://en. & Snyder. (2007). M. Gale Encyclopedia of Medicine. Precautions: May cause urethral bleeding and pain. (2003). The Gale Group. G. R. (2008). S.).. M. D. New Jersey: Pearson Education Inc. Doyle. Vol. Journal of the Royal College of Physicians of Edinburgh.. Abd-El-Hay (28 September 1991). (2007).– Oral intake restricted before surgery . (2002). 4. Saunders. "Per Rectum: A History of Enemata". Reference: Abd-El-Maeboud.. The hypothesis is that the drug passes into the draining veins around the urethra and then passes backwards into the penile erection chambers through these veins. Not suitable for patients with diarrhea 3. B. pp. E. (December 2005). Mahmoud and S. S. (2009). Lynda Price (20 December 2006). Seventh Edition. Localized action reduced systemic distribution Disadvantages: 1. The problem of patient acceptability 2.wikipedia. El-Naggar.. Saunders. Journal of Clinical Nursing (Blackwell Publishing): 98–103. It acts like a direct injection. H. A. Fundamentals of Nursing (Concepts. Inc. The Lancet (Elsevier Science): 798–800. "Rectal suppository insertion: the reliability of the evidence as a basis for nursing practice". Kozier. Mc Graw-Hill Concise Dictionary of Modern Medicine. Possible incomplete absorption Administration: Male: Involves placing a special device into the end of the urinary passageway of the penis and dispensing the small suppository into the urethra after having urinated to wet the urethra. "Rectal suppository: commonsense and mode of insertion".d. The McGraw-Hill Companies..