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oxycodone/acetaminophen Trade Classification Name opioid Percocet analgesics Peak Onset Duration 60-90 min 10-15 min 3-6 hr Mechanism of action and indications (Why med ordered) Binds to opiate receptors in the CNS Alters the perception of and response to painful stimuli, while producing generalized CNS depression Management of moderate to severe pain Interactions with other patient drugs, OTC or herbal medicines (ask patient specifically) Additive CNS depression with alcohol, antihistamines, and sedative/hypnotics Dose Route Time/frequency 5/325 po q 4 hrs prn 1-2 tabs For IV meds, compatibility with IV drips and /or solutions N/A Nursing Implications (what to focus on) Contraindications/warnings/interactions Hypersensitivity, avoid chronic use during lactation Common side effects confusion, sedation, RESPIRATORY DEPRESSION, constipation Lab value alterations caused by medicine May increase plasma amylase and lipase levels
Be sure to teach the patient the following about this medication May be administered with food or milk to minimize GI irritation, Instruct patient on how and when to ask for pain medication, Medication may cause drowsiness or dizziness. Advise patient to call for assistance when ambulating or smoking. Caution patient to avoid driving and other activities requiring alertness until response to medication is known, Advise patient to make position changes slowly to minimize orthostatic hypotension, Encourage patient to turn, cough, and breathe deeply every 2 hr to prevent atelectasis Nursing Process- Assessment Assessment Evaluation (Pre-administration assessment) Why would you hold or not give this Check after giving Assess type, location, and intensity med? Decrease in severity of pain without a of pain prior to and 1 hr (peak) If respiratory rate is <10/min, assess level significant alteration in level of after administration. of sedation. Physical stimulation may be consciousness or respiratory status sufficient to prevent significant Assess bowel function routinely. hypoventilation. Dose may need to be Prevention of constipation should be decreased by 25-50%. Initial drowsiness instituted with increased intake of will diminish with continued use fluids and bulk, and laxatives to minimize constipating effects. Stimulant laxatives should be administered routinely if opioid use exceeds 2-3 days, unless contraindicated