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GENERAL INFORMATION GENERIC NAME: MEFENAMIC ACID ORAL BRAND NAME: Ponstan CLASSIFICATION: Nonsteroidal, antiinflammatory drug DOSAGE

: 500mg/cap ROUTE: PO FREQUENCY: Every 6 hours

MECHANISM OF ACTION Ponstant SF is a nonsteroidal antiinflammatory drug (NSAID) that exhibits anti-inflammatory, analgesic, and antipyretic activities in animal models. The mechanism of action of Ponsant, like that of other NSAIDs, is not completely understood but may be related to prostaglandin synthetase inhibition

INDICATION

CONTRAINDICATION .

SIDE EFFECTS

NURSING RESPONSIBILITIES

-Relief of pain including muscular, rheumatic, traumatic, dental, postoperative and postpartum pain, headache, migraine, fever and dysmenorrhea, pain from rheumatoid arthritis (RA) including Still s disease, soft tissue injuries, Therapy should not exceed 7 days.

-Hypersensitivity. -Active ulceration or chronic inflammation of either the upper or lower gastrointestinal tract (GIT). -If diarrhea or skin rash appears, the drug should be stopped at once. -Blood disorders, poor platelet function. Kidney or liver impairment. Children less than 14 yrs.

-Gastrointestinal (GI) discomfort, diarrhea or constipation, gas pain, nausea, vomiting, drowsiness and dizziness have been observed. -Peptic ulceration, nervousness, visual disturbances, skin rash, urticaria, occasional allergic glomerulonephritis, asthma may be precipitated, dyspepsia, autoimmune hemolytic anemia, bronchoconstriction. -Signs of hemolytic anemia should be watched in cases when the drug is taken for prolonged period of time. SIDE EFFECTS

Assess patient s pain before therapy: location, duration, precipitating and alleviating factors.

GENERAL INFORMATION

MECHANISM OF ACTION

INDICATION

CONTRAINDICATION

NURSING RESPONSIBILITIES

Generic: Nifedipine

Brand Name: Calcibloc

Thought to inhibit calcium ion influx across cardiac and smooth muscle cells, decreasing contractility and oxygen demand. Also may dilate coronary arteries and arterioles.

Hypertension. y Contraindicated in patients hypersensitivity to drug. y Use cautiously in patients with heart failure or hypotension and in elderly patients. Use CNS: dizziness, lightheadedness, headache, weakness, somnolence, syncope, nervousness. CV: flushing, peripheral edema, heart failure, MI, hypotension, y Monitor blood pressure regularly, especially in patients who take beta-blockers or antihypertensives. y Instruct patient to swallow extended-release tablets without breaking, crushing or chewing

pruritus NURSING RESPONSIBILITIES o Hypersensitivity Peptic ulcer Hepatic disease Lactation Hemorrhage Severe hypotension Assess for vit b deficiency o o Advise patient that flushing and increase in feelings of warmth will occur Instruct patient to rise slowly from lying or sitting . palpitations. HDL. y Tell patient to protect capsules from direct light and moisture and to store at room temperature. pulmonary edema.Classification: Antilianginal extended-release tablets cautiously in patients with severe GI narrowing. hepatotoxicity GU: hyperurecemia. Dosage: 30mg/tab Musculoskeletal: muscle cramps Frequency: once a day Respiratory: dyspnea. constipation. protein. EENT: nasal congestion GI: nausea. hypoalbuminuria INTEG: flushing. abdominal discomfort. diarrhea. dry skin. vomiting. paresthesis CV: postural hypertension EENT: blurred vision GI: nausea. Skin: rash. y Advise patient to avoid taking drug with grapefruit juice. coughs. them. acts directly on vascular smooth muscle. triglycerides and lipoprotein INDICATION Supplementation of vit B6 and B12 due to loss of this essential vitamin in uptake of Metformin and Isoniazid CONTRAINDICATION o o o o o o SIDE EFFECTS CNS: headache. reducesLDL. pruritus Route: PO GENERAL INFORMATION Vit b complex Beetab MECHANISM OF ACTION Needed for conversion of fats. glycosuria. rash. jaundice. carbohydrates by oxidation-reduction . causing vasodilation.

instruct patient to have small. y For GI symptoms such as nausea and vomiting. Blocks the final step of acid production Treatment of GERD heartburn and other symptoms Hypersensitivity to omeprazole or other proton pump inhibitors y Assess for hypersensitivity to any proton pump inhibitor or hepatic impairment Short-term treatment for erosive esophagitis y Obtain baseline liver function tests and monitor periodically during the course of therapy y Instruct patient to take drug at least 1 hr before meals y Instruct patient to report severe headache. darkening of the skin. fever. chills. y Instruct patient to limit activities to those that do not require alertness and precision as the drug may cause vertigo and dizziness .GENERAL INFORMATION Generic Name: esomeprazole Brand Name: Nexium Classification: Proton pump inhibitor Dosage: 40mg/tab OD Frequency: BID Route: Oral MECHANISM OF ACTION INDICATION CONTRAINDICATION SIDE EFFECTS Headache Vertigo Dizziness Insomia Apathy Anxiety Paresthesias URI symptoms Sinusitis Cough Epistaxis Rash Inflammation Urticaria Prurtus Alopecia Dry skin NURSING RESPONSIBILITIES Suppress gastric acid secretion by specific inhibition of the hydrogen-potassium ATPase enzymes system at the secretory surface of the gastric parietal cells. frequent meals. changes in color of urine or stool. worsening of symptoms.

memory loss. which is responsible for the synthesis of prostaglandin and thromboxane. Citicoline helps recovery CVD in acute phase & recovery phase. Potentially Fatal: Gastric erosion. Prophylaxis of MI. Mild to moderate pain and fever. lactation GENERAL INFORMATION MECHANISM OF ACTION INDICATION CONTRAINDICATION SIDE EFFECTS NURSING RESPONSIBILITIES GENERIC NAME: CITICOLINE BRAND NAME: It increases blood flow and O2 consumption in the brain. angioedema. It is also involved in the biosynthesis of lecithin. angioedema. urticaria and epigastric discomfort. gout. severe renal or hepatic impairment. Signs and symptoms of cerebral insufficiency (dizziness.GENERAL INFORMATION Generic Name: Aspirin Brand Name: Aspillet Dosage: 100mg/tab Route: PO Frequency: OD Classification: Anticoagulants. poor Parasympathetic hypertonia Gastrointestinal disorders. It inhibits cyclooxygenase. Insomnia Headache . Nonst eroidal Antiinflammatory Drugs (NSAIDs) MECHANISM OF ACTION Aspirin is an analgesic. . It also inhibits platelet aggregation. Antiplatelets & Fibrinolytics (Thrombolytics). rhinitis. paroxysmal bronchospasm and dyspnoea. salicylism. anti-inflammatory and antipyretic. bronchospasm. severe. SIDE EFFECTS GI disturbances. active peptic ulceration. NURSING RESPONSIBILITIES Should be taken with food. prolonged bleeding time. tinnitus. CV collapse and resp failure. urticaria or rhinitis). ). CNS depression which may lead to coma. ulceration and bleeding. patients with haemophilia or haemorrhagic disorders. INDICATION Pain and inflammation associated with musculoskeletal and joint disorders. occasionally fatal exacerbation of airway obstruction in asthma Hepatotoxicity. CONTRAINDICATION Hypersensitivity (attacks of asthma.

Prolonged bleeding time. or other pathologic conditions) History of GI bleeding/ulcer disease Concurrent use of strong Advise patient to notify health care Assess patient for symptoms of stroke. is expected Instruct patient to take medication exactly as directed.and dose-dependent. & their sequelae) Diarrhea Low or High blood pressure Nausea Blurred vision Chest Pains GENERAL INFORMATION MECHANISM OF ACTION INDICATION CONTRAINDICATION SIDE EFFECTS NURSING RESPONSIBILITIES Generic: Clopidogrel Brand Name: Plavix Inhibits platelet aggregation by irreversibly inhibiting the binding of ATP to platelet receptors Classification: Antiplatelet Dosage: 75mg used for the reduction of atherosclerotic events (myocardial infarction. and vascular death) in patients with atherosclerosis documented by recent stroke. concentration. do not double doses . peripheral vascular disease. recent cranial trauma. stroke.ZYNAPSE DOSAGE: 1G/IV q12h from post-traumatic coma and neurological deficits and in those who have had an ischemic cerebral vascular disease such as stroke. which is time. or established peripheral arterial disease. or MI periodically during therapy y Monitor bleeding time during therapy. Hypersensitivity Pathologic bleeding (peptic ulcer. intracranial hemorrhage) Lactation Use Cautiously in: Patients at risk for bleeding (trauma. surgery. Take missed doses as soon as possible unless almost time for next dose. disorientation. recent myocardial infarction.

or unusual bleeding or bruising occurs Route: by mouth . chills.Frequency: once a day CYP2C19 inhibitors Severe hepatic impairment professional promptly if fever. sore throat.