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) Generic Name Trade Name Ceftriaxone Rocephin Peak Onset End of Rapid infusion Classification Dose Route Time/frequency Anti-infectives 1 gram IVPB Q 24 hours Duration Normal dosage range 12-24 hours For most infections, 0.5-1 gram q 12 hours, or 1-2 grams q 24 hours For IV meds, compatibility with IV drips and/or solutions NaCL, D5W, D10W, LR Rate: administer over 15-30 minutes Nursing Implications (what to focus on) Contraindications/warnings/interactions .hypersensitivity to penicillins and cepholosporins. Common side effects Nausea, vomiting, diarrhea, rashes, pain, phlebitis
Why is your patient getting this medication Elevated WBC count Mechanism of action and indications (Why med ordered) binds to bacterial cell causing cell death, indicated for a wide range of infections including respiratory infections.
Interactions with other patient drugs, OTC or herbal medicines (ask patient specifically) none
Nursing Process- Assessment (Pre-administration assessment) assess signs of infection(vitals, sputum sample, urine, stool, and WBC count) Obtain health history to determine previous use and reactions to penicillin and cephalosporin.
Lab value alterations caused by medicine May cause increase in serum AST, ALT, alkaline phosphatase, bilirubin, LDH, BUN, and creatinine. May rarely cause leucopenia, neutropenia, eosinophilia, lymphocytosis, and thrombocytosis Be sure to teach the patient the following about this medication Report signs of superinfection including furry overgrowth on tounge, loose or foul-smelling stools. Assessment Evaluation Why would you hold or not give this Check after giving med? Monitor injection site for If patient shows signs of phlebitis, long-term: look for hypersensitivity (rash, pruritis, resolution of signs and laryngeal edema, wheezing) symptoms of infection.