Name of drug Gentamycin

Action Inhibits protein synthesis, directly to the 30s ribosomal subunit; bactericidal

Indication Serious infection caused by sensitive strains of Pseudomonas aeruginos, Escherichia coli, Proteus, Klebsiella, or Staphylococcus

Side effects CNS- fever, headache, lethargy, encephalopathy, confusion, dizziness, seizures, numbness, peripheral neuropathy, vertigo, ataxia, tingling CV- headache EENT- ototoxicity, blurred vision, tinnitus GI- vomiting, nausea GU- nephrotoxicity, possible increased in urinary excretion of casts Hematologicanemia, eosinophilia, leucopenia, thrombocytopenia, agranulocytosis Musculoskeletalmuscle twitching, my-asthenia gravislike syndrome

Preferred dose Prescribe dose Injection- 40 mg/mL (adults); 10mg/mL (children) IV infusion (premixed) 40mg, 60mg, 70mg, 80mg, 90mg, 100mg, 120mg; in normal saline solution

Nursing responsibilities >Obtain specimen for culture and sensitivity test before giving first dose. Therapy may begin while awaiting results. > Monitor renal function: urine output, specific gravity, urinalysis, BUN and creatinine levels and creatinine clearance. Report to prescriber evidence of declining renal function. >Watch for signs and symptoms of superinfection (especially of upper respiratory tract) such as continued fever, chills, and increased pulse rate. >Therapy usually continues for 7 to 10 days. If no response occurs in 3 to 5

Respiratory- apnea Skin- rash, uticaria, pruritis, injection site pain Other- anaphylaxis

days, stop therapy and obtain new specimens for culture and sensitivity testing.

Name of drug Ampicillin

Action Inhibits cells-wall synthesis during bacterial multiplication (antiinjection, penicillins)

Indication >respiratory tract or skn and skin structure infections >GI infections or UTI’s >Bacterial meningitis or septicemia >Uncomplicated gonorrhea >To prevent endocarditis in patients having dental, GI and GU procedures

Side effects

Preferred dose

CNS: lethargy, 500 mg TIV every 8 hallucinations, hours seizures, anxiety, confusion, agitation, depression, dizziness, fatigue CV: vein irritation, thromphlebitis GI: nausea, vomiting, diarrhea, glossitis, stomatitis, gastritis, abdominal pain, enterocolitis, pseudomembranous colitis, black hairy tongue GU: intestinal nephritis, nephropathy, Vaginitis Hematologic: anemis, thrombocytopenia, purpura, eosinophilia, leukopenia, hymolytic anemia, agranulocytosis Skin: pain at

Nursing responsibilities >before giving drug, ask patient about allergic reaction to penicillins >obtain specimen for culture and sensitivity tests before giving first dose >given drug 1-2 hours before 2-3 hours after meals >monitor sodium level because each gram of ampicillin contains 2.9 mEq of sodium >watch for sign and symptoms of hypersensitivity, such as reythematous maculo-popular rash, urticaria, and anaphylaxis >inform patient to notify prescriber if rash, fever, or chills develop.

injection site Other: hypersensitivity reaction, overgrowth of nonsusceptible organisms

Name of drug USN with combivent

Action Relaxes bronchial, uterine, and vascular smooth muscle by stimulating beta receptors (bronchodilators)

Indication >to prevent or treat bronchospasm in patients with reversible obstructive airway disease >to prevent exercise-induced bronchospasm

Side effects CNS: tremor, ner5vousness, dizziness, insomia, headache, hyperactivity, weakness, CNS stimulation, malaise CV: tachycardia, palpitation, hypertension EENT: dry and irritated nose and throat with inhaled form, nasal congestion, epistaxis, hoarseness GI: heartburn, nausea, vomiting, anorexia, altered taste, increased appetite Metabolic: hypokalemia Musculoskeletal: muscle cramps Respiratory: bronchospasm, cough, wheezing,

Preferred dose ½ + 2cc NSS every 6 hours

Nursing responsibilities >back tapping after nebulization >instruct patients to gargle with water after nebulization because it can cause throat irritation

dyspnea, bronchitis, increased sputum Other: sensitivity reaction

Name of drug Ranitidine

Action Competitively inhibits actions of histamine on the H2 at receptors sites of parietal cells, decreasing gastric acid secretion (antiulcerance)

Indication >duodenal and gastric ulcer; pathologic hypersecretory conditions, such as Zollinger Elison syndrome >maintenance theory for duodenal/gastric ulcer >erosive esophagitis >heartburn

Side effects CNS: vertigo, malaise, headache EENT: blurred vision Hepatic: jaundice Other: burning and itching at injection site, anaphylaxis, angioedema

Preferred dose 50 mg TIV

Nursing responsibilities >assess patient for abdominal pain. Note presence of blood in emesis, stool, or gastric aspirole

Name of drug Omeprazole

Action Inhibits activity of acid (proton) pump and binds to hydrogen-potassium


Side effects

Preferred dose

Nursing responsibilities

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