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Mezić Research Group Dynamical Systems and Nonlinear Control Theory

Motivation: Microfluidic manipulation

• Fully integrated lab on chip • Mixing, concentration, pumping, separation of fluids and •
particles in microchannels Example: Mixing for bioassays
goal: Improve reaction rate in traditional and microarray biosensors via mixing.

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Mezić Research Group Dynamical Systems and Nonlinear Control Theory

Motivation: Microfluidic manipulation
• Solution: Integrated electrodes
generating AC electrothermal mixing

• Electrothermal force:
interaction of gradients in conductivity and permittivity (produced by Joule Heating) with electric field

• Advantages:
 Easy integration  AC=>avoid electrolysis  Effective for high conductivity solutions
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Mezić Research Group Dynamical Systems and Nonlinear Control Theory

Outline
• Standard numerical model for ACET • Experimental discrepancy for high conductivity • Solution: strong thermo-electric coupling using Comsol
software

• Results • Conclusion and Future works
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Mezić Research Group Dynamical Systems and Nonlinear Control Theory

Standard numerical model for ETF
• Electric Field • Temperature Field • Electrothermal Body Force

• Fluid velocity Field

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Mezić Research Group Dynamical Systems and Nonlinear Control Theory

Standard numerical model for ETF
Estimation of velocity amplitude voltage dependence => Temperature: ΔT ~ V2 => Velocity: u~

=> u ~ ΔT E2

u ~ V4
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Mezić Research Group Dynamical Systems and Nonlinear Control Theory

Experimental Setup:

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Mezić Research Group Dynamical Systems and Nonlinear Control Theory

Comsol Implementation

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Mezić Research Group Dynamical Systems and Nonlinear Control Theory

Comsol Implementation

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Mezić Research Group Dynamical Systems and Nonlinear Control Theory

Standard numerical model for ETF
Estimation of velocity amplitude voltage dependence => Temperature: ΔT ~ V2 => Velocity: u~

=> u ~ ΔT E2

u ~ V4
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Mezić Research Group Dynamical Systems and Nonlinear Control Theory

Experimental discrepancy

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Mezić Research Group Dynamical Systems and Nonlinear Control Theory

Strong Thermo-Electric Coupling

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Mezić Research Group Dynamical Systems and Nonlinear Control Theory

Results:

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Mezić Research Group Dynamical Systems and Nonlinear Control Theory

Results:

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Mezić Research Group Dynamical Systems and Nonlinear Control Theory

Conclusion
Strong thermo-electric coupling and Temperature dependent expression of parameters are necessary to correctly model ACET at high gradient of temperature.

Future Works
• Include buoyancy to the model. • Check for which parameters buoyancy is NOT
negligeable.
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