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  • Introduction To Nuclear Medicine: Sania Rahim PGY 4 BCM C/o 2008

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    'Hot' nodules take up more iodine and are thought to be hyperactive and have a low probability of cancer 'cold nodules don't and are more likely to be malignant' bone scans Based on the principle of bone turnover is BAD! 'hot things are hot, but so are degenerative processes, infection, fracture and certain benign etiologies' HIDA Scan HIDA scans use a radiopharmaceutical that mimics bile

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    Nuclear Medicine

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    'Hot' nodules take up more iodine and are thought to be hyperactive and have a low probability of cancer 'cold nodules don't and are more likely to be malignant' bone scans Based on the principle of bone turnover is BAD! 'hot things are hot, but so are degenerative processes, infection, fracture and certain benign etiologies' HIDA Scan HIDA scans use a radiopharmaceutical that mimics bile

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    81 views28 pages

    Introduction To Nuclear Medicine: Sania Rahim PGY 4 BCM C/o 2008

    Uploaded by

    asfadsi23
    'Hot' nodules take up more iodine and are thought to be hyperactive and have a low probability of cancer 'cold nodules don't and are more likely to be malignant' bone scans Based on the principle of bone turnover is BAD! 'hot things are hot, but so are degenerative processes, infection, fracture and certain benign etiologies' HIDA Scan HIDA scans use a radiopharmaceutical that mimics bile

    Copyright:

    Attribution Non-Commercial (BY-NC)
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 28

    IntroductiontoNuclearMedicine

    SaniaRahim PGY4 BCMc/o2008

    BasicsofGammaRaydetection

    VQScan
    Usesoneradiopharmaceuticaltoevaluate perfusion Usesasecondradiopharmaceuticalto evaluateventilation Mismatch betweenperfusionandventilation isaPE

    ThyroidScan
    Generallyspeaking: ThyroidScan:Evaluatenodulesfelton palpation/seenonimaging Hot nodulestakeupmoreiodineandare thoughttobehyperactiveandhavealow probabilityofcancer Cold nodulesdonottakeupiodineandhave aremorelikelytobemalignant

    ThyroidUptake
    Usesthecomparisonoftheknownquantityof administeredradiopharmaceuticaltothe emittedcounts givenoffbythethyroidgland toestimatetheactivityofthethyroid Moreactivethyroids(generallyGraves Disease)haveHIGHERuptakes Alsousedintreatmentplanning

    ThyroidScintigraphy

    BoneScans
    Basedontheprincipleofboneturnoveris BAD! Blasticlesionsarehot,butsoare degenerativeprocesses,infection,fracture andcertainbenignetiologies Coldthingscanbebadtoo!Lyticlesionsand avascularnecrosis Readingscansisaboutrecognizingpatterns andcorrelatingtohistory

    ThreePhaseBoneScans
    Sameprincipleasdelayedbutwithtwo additionalphasestoassesshyperemiain tissueandinbone Osteomyelitisishotinallthreephases Cellulitisorsofttissueinfectionhotinthefirst phasebutnormalinthesecondtwo Acutefracturecanhavesimilarappearanceto osteomyelitis

    GastricEmptyingStudies
    Usesradiolabeledfood(yum!) Patternofgammaemissioncorrespondsto transitoffood Canwatch digestionorthelackthereofand diagnosegastroparesis

    HIDAScan
    HIDAscansusearadiopharmaceuticalthatmimicsbile. Canvisualizeliverdysfunctionbyevaluateabilityofthe livertoextracttheradiopharmaceuticalfromtheblood Ifthereisagallbladderthatisnotedematous (hallmarkofcholecystitis)theradiopharmaceutical shouldenterit IfitDOESNTscanisconsistentwithacutecholecystitis Ifthepharamceuticalentersthegallbladderthe patientdoesnothaveacutecholecystitis

    HIDAScan

    PETPhysics

    WhichCancers?
    PETapprovedforBreast,Lung,Prostate,Head andNeckand(most)Lymphomas. AlsousedinMultipleMyeloma,Melanoma, GIST,andSarcomas Notusefulinrenalcellcancer,bladdercancer becauseofphysiologicactivity Notgreatforlookingatprimarycoloncancers butgreatatcolonmets

    FalsePositivesofPET
    Manypitfalls,experiencedreadersneeded! Difficulttodiscriminatetreatedrelated changes(inflammation)frominfectionfrom cancer Degenerativechangesandenthesopathycan behot Socaninflammatory/granulomatousdiseases

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