Generic Name Fluticasone

Trade Name Advair

Classification Anti-inflammatory, antipruritic

Dose 1 Puff Onset

Route INH Peak

Time/frequency RTBID Duration

Administration/Handling Inhalation: Shake container well. Instruct pt to exhale completely. Place mouthpiece fully into mouth, inhale, hold breath as long as possible before exhaling. Allow at least 1 min between inhalations. Rinsing mouth after each use decreases dry mouth, hoarseness.

Reason for Medication: Long-term control of persistent bronchial asthma. Assists in reducing, discontinuing oral corticosteroid therapy Teaching  Do not change dose/schedule or stop taking drug; must taper off gradually under medical supervision.  Maintain fastidious oral hygiene.  Rinse mouth with water immediately after inhalation (prevents mouth/throat dryness, oral fungal infection)  Increase fluid intake (decreases lung secretion viscosity

Action Controls rate of protein synthesis, depresses migration of polymorphonuclear leukocytes, reverses capillary permeability, stabilizes lysosomal membranes. Therapeutic Effect: Prevents, controls inflammation For IV meds, compatibility with IV drips and/or solutions N/A Contraindications: Untreated localized infection of nasal mucosa. Inhalation: Primary treatment of status asthmaticus, acute exacerbation of asthma, other acute asthmatic conditions. Cautions: Untreated systemic ocular herpes simplex viral infection; untreated fungal, bacterial infection; active or quiescent tuberculosis. Side effects Frequent: Inhalation: Throat irritation, hoarseness, dry mouth, cough, temporary wheezing, oropharyngeal candidiasis (particularly if mouth is not rinsed with water after each administration) Adverse effects/Toxic Reactions None known. Lab value alterations None Significant

Interactions: DRUG: Ritonavir may increase concentration, reduce serum cortisol concentration. HERBAL: None significant. FOOD: None known.

Baseline Assessment Establish baseline history of skin disorder, asthma, rhinitis Evaluation  Monitor rate, depth, rhythm, type of respiration; quality/rate of pulse.  Assess lung sounds for rhonchi, wheezing, rales.  Monitor ABGs.  Assess oral mucous membranes for evidence of candidiasis.

Reasons to Hold

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