References Background 1. Allmeling, C.; Jokuszies, A.; Reimers, K.; Kall, S.; Vogt, P. M.

, Use of spider silk fibres as an innovative material in a biocompatible artificial nerve conduit. Journal of Cellular and Molecular Medicine 2006, 10, (3), 770-777. 2. Altman, G. H.; Diaz, F.; Jakuba, C.; Calabro, T.; Horan, R. L.; Chen, J. S.; Lu, H.; Richmond, J.; Kaplan, D. L., Silk-based biomaterials. Biomaterials 2003, 24, (3), 401416. 3. Bini, E.; Foo, C. W. P.; Huang, J.; Karageorgiou, V.; Kitchel, B.; Kaplan, D. L., RGDfunctionalized bioengineered spider dragline silk biomaterial. Biomacromolecules 2006, 7, (11), 3139-3145. 4. Dong, Z. Y.; Lewis, R. V.; Middaugh, C. R., Molecular Mechanism of Spider Silk Elasticity. Archives of Biochemistry and Biophysics 1991, 284, (1), 53-57. 5. Elices, M.; Perez-Rigueiro, J.; Plaza, G. R.; Guinea, G. V. JOM 2005, 57. 6. Foo, C. W. P.; Kaplan, D. L., Genetic engineering of fibrous proteins: spider dragline silk and collagen. Advanced Drug Delivery Reviews 2002, 54, (8), 1131-1143. 7. Gosline, J. M.; Denny, M. W.; Demont, M. E., Spider Silk as Rubber. Nature 1984, 309, (5968), 551-552. 8. Gosline, J. M.; Guerette, P. A.; Ortlepp, C. S.; Savage, K. N., The mechanical design of spider silks: From fibroin sequence to mechanical function. Journal of Experimental Biology 1999, 202, (23), 3295-3303. 9. Grubb, D. T.; Jelinski, L. W., Fiber morphology of spider silk: The effects of tensile deformation. Macromolecules 1997, 30, (10), 2860-2867. 10. Guan, Z. B., Supramolecular design in biopolymers and biomimetic polymers for properties. Polymer International 2007, 56, (4), 467-473. 11. Hayashi, C. Y.; Shipley, N. H.; Lewis, R. V., Hypotheses that correlate the sequence, structure, and mechanical properties of spider silk proteins. International Journal of Biological Macromolecules 1999, 24, (2-3), 271-275. 12. Hinman, M. B.; Jones, J. A.; Lewis, R. V., Synthetic spider silk: a modular fiber. Trends in Biotechnology 2000, 18, (9), 374-379. 13. Hu, X.; Vasanthavada, K.; Kohler, K.; McNary, S.; Moore, A. M. F.; Vierra, C. A., Molecular mechanisms of spider silk. Cellular and Molecular Life Sciences 2006, 63, (17), 1986-1999. 14. Ittah, S.; Cohen, S.; Garty, S.; Cohn, D.; Gat, U., An essential role for the C-terminal domain of a dragline spider silk protein in directing fiber formation. Biomacromolecules 2006, 7, (6), 1790-1795. 15. Jin, H. J.; Kaplan, D. L., Mechanism of silk processing in insects and spiders. Nature 2003, 424, (6952), 1057-1061. 16. Kubik, S., High-performance fibers from spider silk. Angewandte ChemieInternational Edition 2002, 41, (15), 2721-+. 17. Lefevre, T.; Rousseau, M. E.; Pezolet, M., Protein secondary structure and orientation in silk as revealed by Raman spectromicroscopy. Biophysical Journal 2007, 92, (8), 2885-2895.

O. van Beek. 3. M.. 56. S.. Journal of the American Chemical Society 2007. Marcotte. 82. D.... and beta-hairpins. 33. Regenerated spider silk: Processing. Macromolecules 2000.. Symp. M. Tensile properties of Argiope trifasciata drag line silk obtained from the spider's web. T. 24. R. HernandezCruz. 2003. W. K. ASAP.10. D. Jelinski. 22. 33. (9).. 84-87. A. 19. A. Ray. Phillips. The molecular structure of spider dragline silk: Folding and orientation of the protein backbone. 774. Liivak. Tanner. Chemical Engineering Science 2001. Elices. D. Synthetic Fibres 2004. The Kevlar Story .. (13). M. 20. Scheibel. (6). B.. 25. (5245). Deformation induced hydrophobicity: implications in spider silk formation. Rousseau. H. J. Scheller. 2.. C. R.. M. 3762-3774. L.. Pezolet. Lele. P. Llorca. Spider silks: recombinant synthesis.. A. Biotechnological Production of Spider-Silk Proteins Enables New Applications. et al. Perez-Riguero.3. F. 30. Hess. 26.18. Spider silk: Ancient ideas for new biomaterials. Seidel. K. (1). Calve. Jelinski. beta-turns.. Meier. H. A. 7.. U. 2245-2251.3. spinning. Rotondi. A. Macromolecules 1994. Mat. 28. J. M. Hitchcock.. Scheibel. L.. V. 401-409. 3897-3905. Meier.. Nephila clavipes Spider Dragline Silk Microstructure Studied by Scanning Transmission X-ray Microscopy. S. Macromolecular Bioscience 2007. West.... Vollrath. A. 271. E. Adaska. W... et al. L. (20). assembly. Joshi. S. 649-654.. Biopolymers 2006. Spider silk. J.an Advanced Materials Case-Study. Journal of Applied Polymer Science 2001. Liquid crystalline spinning of spider silk.. J. Michal. A. (18).. L. P. J.. Molecular Farming 2004.. 10-17. Vollrath. Proceedings of the National Academy of Sciences of the United States of America 2002. Molecular orientation and twocomponent nature of the crystalline fraction of spider dragline silk.. Z. E. Production of spider silk proteins in transgenic tobacco and potato. M. van Beek. Res. W.. Vendrely. Ji. Apr/Jun. H. 99. T. D. S. D. 27. B.. 106. 29. Y. Gierasch. 34. Stark.. properties. Solid-State C-13 Nmr of Nephila-Clavipes Dragline Silk Establishes Structure and Identity of Crystalline Regions. T. J. Knight. Simmons. 5793-5800. 775-780. Yang. Proc. Jelinski. 40. Madhavamoorthi. (6828). 35. 1026610271. Chemical Reviews 2006. (9). C. Zax. Lewis. 21. . D. 31. C. Viney. and engineering of synthetic proteins. D. A. Biomacromolecules 2007. and structure..1-2. 28.. 541-548.. Nature 2001.. Angewandte Chemie-International Edition in English 1989. M. 171-181. 32. Macromolecules 2007.J. Soc. Stephens. I. B. J.. 410.. 84. 13-22... 23. Simmons.. G. Mashelkar. Microbial Cell Factories 2004.. 5235-5237. (16).. 1995-2001. B. Molecular disorder and structure of spider dragline silk investigated by two-dimensional solid-state NMR spectroscopy.. Natural polypeptide scaffolds: beta-sheets. (3). (5). D. Science 1996. R. F. Fitzgerald. Macroscopic fibers self-assembled from recombinant miniature spider silk proteins. 27. 129. M. Conrad. Grubb. P.

2003.. 34. Patent 4.. C. Nucleotide Chemistry . U. W. Patent.. 401-410. 245-248.. (1). 44. O'Brien. 37. (5554).. P. P. Science 2002. 20040102614. C. Kaplan. Shao. J.968. Vollrath. H. S. C. Y. Fahnestock. H. Construction. Polymers for Advanced Technologies 2003..S. M. R. 10. Karatzas. Z... 49. C. 38. (3). M. Duguay. R.. Fahnestock. 1-10. 82. Biomacromolecules 2005.. M... Work. WO03057727. 33-39. R. X. Advanced Materials 1998. Conticello. Y. 5.M.. 6. M. Smeenk.. F. Welsh. A. Dattagupta. PCT Int. J. C. D. S. PCT Int. F.. A. S. 47.602.. Appl. 1990. Self-assembly of a polypeptide multi-block copolymer modeled on dragline silk proteins. van Hest. R. Tetrahedron Letters 1983. 39. Bedzyk. L. Turcotte. Mcgrath. P. 1968-1971. Huang. (18)..... 1185-1195. 47. J. D. Structure of a Protein Superfiber . 10879-10885. L. Porter. 53. 10. Stunnenberg. Applied Microbiology and Biotechnology 1997. Cuniff. Emerson. A. Advanced Materials 2005. V. et al. (2). P.. Z. M. F. 122.. C. Chemical Methods 51. van Hest. Nylons from nature: Synthetic analogs to spider silk. P. N. 23-32. Irwin. Spider silk fibers spun from soluble recombinant silk produced in mammalian cells. 7120-7124. Controlled assembly of macromolecular beta-sheet fibrils. H. P. An Investigation of Several Deoxynucleoside Phosphoramidites Useful for Synthesizing Deoxyoligonucleotides. Applied Microbiology and Biotechnology 1997. Ayres.. F.. E. L. Production of synthetic spider dragline silk protein in Pichia pastoris. (2). Porter. P. Otten. D.. .. 205-212. 43. B. et al. (34)... Yang. Lazaris. J. 45. Knight. Lowik.. Journal of the American Chemical Society 2000.. Cloning. Zhou. Biosynthetic Methods 40.10. R. 2001.. H. (15). Biochemistry 1995.. Zhou. C.. L. 295. 2004. C. M. K. A. (1). Synthetic spider dragline silk proteins and their production in Escherichia coli.. 46. J. (20). Proceedings of the National Academy of Sciences of the United States of America 1990. N. Tirrell. Gardner. Spider silk as a model biomaterial. L. P.. C. S. R. Y. J. N. 42. 50. Apkarian. Angewandte Chemie-International Edition 2005. Chen. 1982. G. 24. Fahnestock.Spider Dragline Silk.. Caruthers. D. 825-831. Xu. Digirolamo. 44. J. J. M. P. H. T. Payne. Vollrath. W. 87. D. Toughness of spider silk at high and low temperatures. (13). Thies. 472-476. Appl.S. 48. Applied Physics aMaterials Science & Processing 2006. V. S. D.. Qu. beta-sheet side chain polymers synthesized by atom-transfer radical polymerization. K. 47. N. Termonia. P. Arcidiacono. D. Mcbride... Soares. U. Karatzas. Adams.. 41. Prince. S... Lewis. 84-89.. Islam. Chretien. M.. 17. and Expression of Synthetic Genes Encoding Spider Dragline Silk. M.. Y. J. 52...... 5014-5015. W. Karatzas. S.36. (1). Journal of Arachnology. WO0156626. J..

.html http://biomed. 1991. (9). American Chemical Society: Washington. C.213-215. Qian. D. Farmer. Yu. 474-475. D. Journal of the American Chemical Society 2001. Winningham. Polymer 2006. 7508-7512.. D. Vol. J. Y. 36. 58. Y. J.aerostar. T. B. T. N...nexiabiotech.. T.. R.htm http://www. W. A modular approach to polymer architecture control via catenation of prefabricated biomolecular segments: Polymers containing parallel beta-sheets templated by a phenoxathiin-based reverse turn mimic.. B. H.com/en/00_home/index. 47. Winningham. Materials Science and Engineering: An Introduction. Viney... Wagner. characterization. B. 59. X. Pollock. J. G. P. (22). G... D.. Thomas. M.. Y. 64. M... John Wiley & Sons. Korley. 453-454. 1983. Ko.C. Byrom. Y. W. Zhou. Pate.. 43. P. Biomacromolecules 2006. 61. Yao.. Callister.. 1994. S.. Rathore. Korley. Conformations in Fibrous Proteins and Related Synthetic Polypeptides. Polymer Preprints 2002. D. Y. Yao. 10831-10842. (47). Parallel Beta-Sheet Conformation in Macrocycles. (4). P. 57. M. 352-366. 7.. Leng. J. Academic Press: New York. Design and synthesis of biomolecular materials based on spider and bombyx mori silks. 1973. Synthesis and characterization of multiblock copolymers based on spider dragline silk proteins. X. Wisconsin. Geno. T.. E. M. Sogah... R.. Xiao.. S. 2003. Shakhashiri. D. Macromolecules 2003. (8). L. and resin spinning of silk-like thermoplastic polyurethanes and polyesters. Kojic. 49. Z. J. Hammond. P. W. X. J. 62. L. Zhou. D. McKinley. 123. Shao. D. B. Adams. Chen. 45. Kaplan. Feigel.. . Rathore.. Hammond. Effect of the degree of soft and hard segment ordering on the morphology and mechanical behavior of semicrystalline segmented polyurethanes.. (2). Biomaterials. Synthesis. 3073-3082. G. P.. Shao. D. T. Chen. O. Sogah. Journal of Polymer Science Part a-Polymer Chemistry 2000. R. R. C. 38. D... A novel silk-based segmented block copolymer containing GlyAlaGlyAla beta-sheets templated by phenoxathiin. J. Chemical Demonstrations.... (20). Books: 63.com/military. Synthesis and solid-state secondary structure investigation of silk-proteinlike multiblock polymers. Images obtained from: http://www2..dupont. 30. Macromolecules 1997. 55. Polymer Preprints 2004. Zhou.com/DuPont_Home/en_US/index.. Sogah. Inc. Sogah. p.1. 56. 66. Stockton Press: New York. Z. A Handbook for Teachers of Chemistry. C. 5231-5239.. 65. Osman. O. Self-assembly of beta-sheets into nanostructures by poly(alanine) segments incorporated in multiblock copolymers inspired by spider silk. D. L. Tetrahedron 1993. P. Fraser. Silk Polymers. T. Z. 862-876.. Z.edu www. H.php B. 2415-2419. J. MacRae. 60.brown..54. Z. D. Knight.

Sign up to vote on this title
UsefulNot useful