Name of the

Drug
Drug
Class
Therapeutic
Action
Indication Contraindications Dosage
&Preparation
Adverse Reaction Nursing
Responsibility


Naproxen


















Nonsteroi
dal anti-
inflammat
ory drug
(NSAID),
Analgesic
(non-
narcotic)

Analgesic,
anti-
inflammator
y, and
antipyretic
activities
largely
related to
inhibition
of
prostagland
Mild to
moderate
pain
Treatmen
t of
primary
dysmenorrh
ea,
rheumatoid
arthritis,
osteoarthr
Contraindicated
with allergy to
naproxen,
salicylates,
other NSAIDs;
pregnancy;
lactation.
Naproxen
conventional
tablets, delayed-
release tablets,
or suspension
250-500 mg twice
daily; may
increase dosage to
1.5 g daily for up
to 6 months
225

Headache,
dizziness,
somnolence,
insomnia,
fatigue,
tiredness,
dizziness,
tinnitus,
ophthalmic
effects
Rash, pruritus,
Give with food
or after meals if
GI upset occurs.
Arrange for
periodic
ophthalmologic
examination
during long-term
therapy.
Institute
emergency














in
synthesis;
exact
mechanisms
of action
are not
known.

itis,
ankylosing
spondyliti
s,
tendinitis
,
bursitis,
acute gout
JTC use:
temporary
relief of
minor
sweating, dry
mucous
membranes,
stomatitis
Nausea,
dyspepsia, GI
pain, diarrhea,
vomiting,
constipation,
flatulence
Dysuria, renal
impairment,
procedures if
overdose occurs:
gastric lavage,
induction of
emesis,
supportive
therapy.

aches and
pains
associated
with the
common
cold,
headache,
toothache,
muscular
aches,
backache,
minor pain
including renal
failure,
interstitial
nephritis,
hematuria
Bleeding,
platelet
inhibition with
higher doses,
neutropenia,
eosinophilia,
leukopenia,
of
arthritis,
pain of
menstrual
cramps,
reduction
of fever
Treatmen
t of
juvenile
arthritis
(naproxen
pancytopenia,
thrombocytopenia
,
agranulocytosis,
granulocytopenia
, aplastic
anemia,
decreased Hgb or
Hct, bone marrow
depression,
menorrhagia
Dyspnea,



only)

hemoptysis,
pharyngitis,
bronchospasm,
rhinitis
Peripheral
edema,
anaphylactoid
reactions to
anaphylactic
shock

Name of the Drug Therapeutic
Action
Indicatio
n
Contraindi
cations
Dosage and
Preparatio
n
Adverse Reaction Nursing Responsibility
Metronidazole
(Flagyl)
ANTI-INEFECTIVES
(amebicides&
antiprotozoals)
Direct -
acting
trichomonacid
e and
amebicide
that works
inside and
outside in
the
intestines.
It's thought
to enter the
cells of
microorganism
s that
contain
nitroreductas
e, forming
unstable
compounds
that binds
The
indicatio
n are
based on
the anti-
parasitic
and
antibacte
rial
activity.
Amebic
liver
abscess,
Intestina
l
amebiasis
,
Trichomon
iasis
Bacteria
l
·
Contraindic
ated with
hypersensiti
vity to
metronidazo
le;
pregnancy
(do not use
Ior
trichomonia
sis in Iirst
trimester).
· Use
cautiously
with CNS
diseases,
hepatic
disease,
1g /
rectum 1hr
prior to
JR
CNS: headache,
seizures, fever,
vertigo, ataxia,
dizziness,
confussion,depre
ssion,
irritability
Vision disorder:
transient vision
disorders such
as diplopia,
myopia
GI: epigastric
pain, pain,
nausea,
vomiting,
diarrhea,
metallic taste,
dry mouth
Hypersensitivity
Reactions: rash,
Always observe the 10 Rights when giving
medication.
Give oral form with meals to minimize GI
Tell pt. he may experience a metallic tas
have dark or red-brown urine.
Instruct pt in proper hygiene
Tell pt to avoid alcohol during metronida
therapy and for atleast one day afterwards
of possibility of dislfiram-like (Antabuse
reaction.
May cause transient visual disorder, dizz
confusion avoid activities requiring alert
like driving a vehicle.
DNA and
inhibits
synthesis,
causing cell
death.
infection
s caused
by
aerobic
microorga
nisms
To
prevent
postopera
tive
infection
in
contamina
ted
colorecta
l surgery
Bacteria
l
Vaginosis
Clostrid
ium
difficle-
associate
d
candidiasis
(moniliasis),
blood
dyscrasias,
lactation.

pruritus,
flushing,
urticaria,
anaphylactic
shocks
GU: darkened
urine, polyuria,
dryness of
vagina,dysuria
diarrhea
and
colitis
Pelvic
Inflammat
ory
disease



Name Of the
Drug
Drug Class Route Therapeuti
c Action
Indication Contraindications Adverse
Effect
Dosage and
Preparations
Nursing
Action
Ferrous
Gluconate
Antianemic
s
PJ an
essential
minerals
found in
hemoglobin
myoglobuli
n
and enzyme
which
entrs the
blood
stream and
is
transporte
d to the
organs of
the
reticuloen
dothelial
system,
where it
is
separated
out and
becomes
prevention
and
treatment
of iron
defiency
anemia
hemochromdosiis,
hemosiredosis, or
ther vidence of
iron overload
anemia not due
to iron defiency
, some products
contain alcohol,
tartrazine or
sulfiles ,
patient with
known intolerance
hypersensivity
seizures,
syncope,
hypotensio
n,
hypertensi
on , taste
disorder
325 mg orally
once a day. Reviews the
patients
right
Recheck the
medical
order

Assess bowel
function
for
constipation
and diarrhea
part of
iron
stones.

Instruct
patient that
stool may
turn in back
black color
and if it is
normal due
to the
medication

Instruct
patient to
intake of
food rich in
Vit C for
better
absorption
of the
medication
Instruct to
increase
oral fluid
intake to
avoid
constipation

Encourage
patient to
increase
intake of
green leafy
vegetable

Jbserve for
seizure ,
tachycardia
and
hypotension

Advice
patient to
report
severe
vomiting and
taste
disorder












Name Of the
Drug
Drug Class Routes Therapeutic
Action
Indications Contraindications Adverse
Effect
Preparations
and Dosage
Nursing
Action
Paracetamol
Analgesia,
Antipyresi
s

PJ,IV,PR,IM Inhibits
prostagland
in
synthesis
in the CNS
and blocks
the pain
impulse
through a
peripheral
action. It
acts on the
hypothalami
c heat-
regulating
center,
producing
peripheral
vasodilatio
n. It
results in
antipyresis
Fever, Relief
of mild to
moderate pain
like
headaches,
muscular
aches and
pain,
toothache,
colds,
earache,
fever due to
tonsillectomy
,
inoculations,
and
vaccinations.
None except
hypersensitivity
to paracetamol).
Side
effects
are well
tolerate
d.
Cramping
,
heartbur
n,
abdomina
l
distenti
on can
be
experien
ced. Jn
a
rarity,
hypersen
sitivity
reaction
s.
ADULTS,
ELDERLY: 325-
650 mg q4-6h
or 1g 3-4
time/day.
Maximum: 4
g/day.
CHILDREN: 10-
15 mg/kg/dose
q4-6h as
If to be
given as
analgesia,
assess onset
type,
location,
duration of
pain.
Can be given
and
produces
analgesic
effect.
needed.
Maximum: 5
doses/ 24
hours.
NEJNATES: 10-
15 mg/kg/dose
q6-8h as
needed.
Rectal: ADULT
S: 650 mg q4-
6h. Maximum:
6 doses/ 24
without
regards to
meals.
Tablets can
be crushed.
Assess
temperature
directly
before and 1
hour after
giving
medication.
hours.
CHILDREN: 10-
20 mg/kg/dose
q4-6h as
needed.
NEJNATES: 10-
15 mg/kg/dose
q6-8h as
needed
Dosage for
Clients with
Renal
If
respirations
are <12/min
(<20/min in
children),
withhold the
medication
and contact
the
physician.
Evaluate for
therapeutic
Impairment:
If creatinine
clearance is
10-50mL/min
the frequency
should be
q6h. If the
creatinine
clearance is
<10mL/min the
frequency
should be
response:
relief of
pain,
stiffness,
swelling;
increasing i
joint
mobility;
reduced join
tenderness;
improve grip
strength.
q8h.

Therapeutic
blood serum
level: 10-30
mcg/mL; toxi
serum level:
200 mcg/mL.








Name Of the
Drug
Drug Class Route Therapeutic
Action
Indicat
ions
Contraindications Adverse
Effect
Preparation and
Dosage
Nursing Action
Ranitidine Histamine H2
antagonists
IV - Inhibits
the action
of histamine
at the H2
receptor
site located
primarily in
gastric
parietal
-Treatm
ent and
prevent
ion of
heartbu
rn,
acid
indiges
tion,
and
sour
stomach
.
Contraindicated
in:
-Hypersensitivity
, Cross-
sensitivity may
occur; some oral
liquids contain
alcohol and
should be avoided
-
Confusio
n,
dizzines
s,
drowsine
ss,
hallucin
ations,
mg q 8 hrs Assessment:
1. History: allergy t
ranitidine, impaire
renal or hepatic
Iunction, lactation
pregnancy.
2. Physical: skin
lesions, orientation
aIIect, liver
evaluation,
abdominal
examination, norm
output, renal Iunctio
tests, CBC

cells,
resulting in
inhibition
of gastric
acid
secretion.
- In
addition,
ranitidine
bismuth
citrate has
in patients with
known
intolerance.
Use Cautiously
in:
- Renal impair-
ment
- Geriatric
patients (more
susceptible to
adverse CNS
headache
-
Arrhythm
ias
-
Altered
taste,
black
tongue,
constipa
tion,
nterventions:
1. Administer ora
drug with meals an
at bedtime.
2. Decrease doses i
renal and liver
Iailure.
3. Provide concurre
antacid therapy to
relieve pain.
4. Administer
dose undiluted, dee
into large muscle
group.
. Arrange Ior regul
Iollow-up including
blood test, to evalua
eIIects.
some
antibacteria
l action
against H.
pylori.

reactions)
- Pregnancy or
Lactation

dark
stools,
diarrhea
, drug-
induced
hepatiti
s,
nausea
-
Decrease
d sperm
count,
impotenc
e
-Gynecom
astia
-Agranul
ocytosis
,
Aplastic
Anemia,
neutrope
nia,
thromboc
ytopenia
- Pain
at IM
site
-Hyperse
nsitivit
y
reaction
s,
vasculit
is