clopidogrel bisulfate, Plavix

GENERIC NAME: clopidogrel bisulfate BRAND NAME: Plavix DRUG CLASS AND MECHANISM: Clopidogrel bisulfate is an anti-platelet drug, that is, a drug that inhibits the ability of platelets to clump together as part of a blood clot. It is similar to ticlopidine (Ticlid) in chemical structure and in the way it works. Unlike ticlopidine, clopidogrel bisulfate does not cause serious reductions of white cells in the blood and, therefore, routine blood testing to determine if the white blood cell count is low is not necessary during treatment. The risk of heart attacks and strokes (which usually are caused by blood clots) is increased in patients with a recent history of stroke or heart attackand patients with peripheral vascular disease. (Peripheral vascular disease is the same as atherosclerotic arterial disease or "hardening" of the arteries in which the arteries become narrowed. It frequently occurs in the legs and often causes claudication or pain in the legs upon walking). Clopidogrel bisulfate is used to reduce the risk of heart attacks and strokes in these patients. Clopidogrel bisulfate was approved by the FDA in 1997. PREPARATIONS: Tablets: 75mg. STORAGE: Tablets should be stored at room temperature, 15-30 C (59-86 F). PRESCRIBED FOR: Clopidogrel is used to prevent strokes and heart attacks in persons who are at high risk. In one large study, clopidogrel bisulfate was more effective than aspirin in reducing heart attacks. The frequency of side effects of clopidogrel bisulfate was similar to aspirin; however, stomach and intestinal bleeding probably occurs less often with clopidogrel bisulfate than with aspirin. DOSING: Clopidogrel bisulfate usually is taken once daily. It can be taken with or without food. Clopidogrel is activated by enzymes in the liver. Individuals who have reduced activity of liver enzymes that activate clopidogrel may not adequately respond to clopidogrel. Alternative treatments should be used for these patients. SIDE EFFECTS: The tolerability of clopidogrel is similar to that of aspirin.Diarrhea, rash, or itching occurs in approximately 1 in 20 persons taking clopidogrel. Abdominal pain also occurs in about 1 in 20 persons, but it is less frequent than with aspirin. Ticlopidine (Ticlid) is an antiplatelet medication quite similar to clopidogrel. It has been associated with a severe reduction in white blood cell count in between 0.8% and 1% of persons. The risk of this dangerous side effect with clopidogrel is about 0.04%, much less than with ticlopidine but twice that of aspirin. Clopidogrel rarely causes a condition called thrombotic thrombocytopenic purpura (TTP) in one out of every 250,000 people. TTP is a serious condition in which blood clots form throughout the body. Blood platelets, which participate in clotting, are consumed, and the result can be bleeding because enough platelets are no longer left to allow blood to clot normally. For comparison, the related drug, ticlodipine (Ticlid), causes TTP 17-50 times more frequently than clopidogrel.


seek for immediate medical help. skin irritation. inform your doctor if you are using any other drug. Consult with your doctor the list of food you need to avoid for controlling the ailments. and chest pain. constipation. helping easier routing of gas. swelling. • Disflatyl tablets may cause drowsiness. Consult a doctor if any of these side effects of Disflatyl tablets become persistent and troublesome. swelling of the face. • Consult with your doctor before using Disflatyl tablets in case of pregnancy or breast-feeding. Ansimar Generic Name : Ansimar . Adults for Endoscopy: 67 Mg of Simethicone as an oral suspension administered just before Endoscopy.. hear and moisture. hives skin rashes. It is prescribed for relief from pressure created by excessive formation of gas bubbles in the stomach and intestine. • Store Disflatyl tablets at room temperature away from direct sunlight. chest congestion. redness. • Avoid overdose. • Avoid using over the counter medication without consulting with your doctor. Common side effects include headache. difficulty in breathing. • Use the medication after taking your meal at bedtime or follow the instructions prescribed by your doctor. In case any of these side effects occur. • Simethicone may interact with other drugs and cause severe side effects. nausea. lips tongue or throat. Keep it safely out of reach of children.tablets amass the gas bubble formed in the stomach and intestine. vitamin supplement or herbal remedies for prevailing ailments. Disflatyl tablets may be prescribed for ailments not listed above. It is important to maintain your diet prescribed by your doctor along with using the medication for effective results. strictly follow the instruction prescribed to you by your doctor. postoperative Gas Pains and Flatulence: 40 to 125 Mg of Simethicone to be administered orally after meal and at bedtime. seek for immediate medical help. avoid using it while driving or operating heavy machinery. Dosage Adults For functional gastric disorder. diarrhea and abdominal cramps. vomiting. Symptoms include extreme allergic reaction. Important information on Disflatyl tablets • Avoid the medication if you are allergic to Simethicone. In case of overdose. Disflatyl tablets side effects Rare cases of side effects associated to Disflatyl tablets have been reported.

vomiting. Contraindications Acute MI. tachypnea. insomnia. extrasystole. NURSING RESPONSIBILITIES: > Use with caution in patients with hypoxemia. Mechanism of Action Bronchodilator. tachycardia.Brand Name: Zuellig Dosage Tab Adult 1 tab bid-tid. albuminuria. epigastric pain. hyperthyroidism. Syr Childn >12 yr 10 mL once-tid. Losartan. renal disease. cephalalgia. lactation. hyperglycemia. Frequently. Adverse Drug Reactions Nausea. in those with history of peptic ulcer and in elderly. > assess for allergic reaction > assess for breath sounds >should be given to a pregnant woman only if clearly needed. <12 yr 6-9 mg/kg FREQUENCY: bid. hypotension. Cozaar GENERIC NAME: losartan BRAND NAME: Cozaar . liver disease. Indications Bronchial asthma & pulmonary disease w/ spastic bronchial component. irritability. patients with CHF have markedly prolonged drug serum levels following discontinuation of Ansimar.

increase serum potassium. Losartan (more specifically. light resistant container. By blocking the action of angiotensin. Rare cases of rhabdomyolysis (muscle breakdown) have been reported. formed in the blood by the action ofangiotensin converting enzyme (ACE).dizziness. is a powerful chemical that attaches to angiotensin receptors found in many tissues but primarily on smooth muscle cells of blood vessels. DOSING: The usual starting dose of losartan for adults is 50 mg daily. Janumet can be used along with exercise and diet to lower down the blood sugar levels in adults having type 2 diabetes. Doses more than 1. It may be used alone or in combination with other drugs. The starting dose of losartan for pediatric patients 6 years of age or older is 0. Losartan may be given with or without food. Angiotensin. valsartan (Diovan). and nasal congestion. Metformin helps reduce the production of glucose (sugar) in liver and also minimizes the glucose absorption by the intestines.DRUG CLASS AND MECHANISM: Losartan is an oral medication that belongs to a class of drugs called angiotensin receptor blockers (ARBs). Be aware that Janumet cannot be used to treat type 1 diabetes.4 mg/kg or 100 mg daily have not been evaluated in pediatric patients. Losartan was approved by the FDA in April 1995. Angiotensin's attachment to the receptors causes the blood vessels to narrow (vasoconstrict) which leads to an increase in blood pressure (hypertension). Janumet -a combination of sitagliptin and metformin which are the oral diabetes medicine to control the levels of blood sugar. The maximum dose is 100 mg daily. and angioedema. Other ARBs include irbesartan (Avapro). Losartan may reduce kidney function in some patients and should not be used by patients who have bilateral renal artery stenosis (narrowing of both arteries going to the kidneys). the chemical formed when the liver converts the inactive losartan into an active chemical) blocks the angiotensin receptor. .7 mg/kg up to 50 mg once daily. insomnia. 50 and 100 mg STORAGE: Tablets should be stored at room temperature in a tightly closed. SIDE EFFECTS: diarrhea. The total daily dose may be divided and administered twice daily. muscle cramps. Sitagliptin (Junavia) helps in regulating the insulin levels which the body produces after eating something. PREPARATIONS: Tablets: 25. Losartan also may cause a persistent cough. andcandesartan (Atacand). PRESCRIBED FOR: Losartan is used for treating hypertension. losartan dilates blood vessels and thereby reduces blood pressure. left ventricular hypertrophy (increase in muscle) and diabetic nephropathy (kidney disease).

. cold or numb feeling in the legs and arms. Just call your physician if you feel some serious side effects. loss of appetite. Side Effects of Janumet Janumet may lead to lactic acidosis which can slowly become worse over time. vomiting and fast nausea. feeling very tired or weak and dizziness. diarrhea. stomach pain. mild exertion. lips and breathing difficulty. or cold symptoms like stuffy or runny nose. heart rate. sore throat. upset stomach. tongue. irregular or slow heart rate. nausea with vomiting. or rapid weight gain or swelling Less serious side effects of Janumet may include: mild nausea. swelling on face. muscle pain. such as:       pancreatitis i. sneezing.e. Some of the other symptoms of an allergic reaction to Janumet include hives.Try to avoid drinking the alcohol while taking this drug as the alcohol can lower the blood sugar level and may increase the chances of lactic acidosis. breathing trouble. headache. excruciating pain in the upper abdomen. weakness. Seek emergency help when you experience mild signs of lactic acidosis like weakness. short of breath. throat.

Dilt-XR. and certain heart rhythm disorders. Diltiazem Hydrochloride XR. Cardizem CD. fainting. Dilt-CD. slow heartbeats. Cartia XT. difficulty breathing. skin pain. or if you have:    certain heart conditions. or throat. Avoid exposure to sunlight or tanning beds. angina (chest pain). blistering skin rash. Be careful if you drive or do anything that requires you to be alert. Cardizem LA. weakness.fever. or if you have recently had a heart attack. Diltiazem can make you sunburn more easily. sore throat. Cardizem SR. redness. upper stomach pain. swelling in your hands or feet. Diltia XT. sore throat. Diltiazem side effects Get emergency medical help if you have any of these signs of an allergic reaction to diltiazem: hives. Taztia XT. What should I avoid while taking diltiazem? Diltiazem may impair your thinking or reactions. lips. liver disease. tongue. itching. followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling. Diltiazem Hydrochloride CD. or tingly feeling). FDA pregnancy category C. especially "sick sinus syndrome" or "AV block" (unless you have a pacemaker). dark urine. Grapefruit and grapefruit juice may interact with diltiazem and lead to potentially dangerous effects. clay-colored stools. Tiazac. Cardizem Monovial. dizziness. upset stomach. Diltiazem Hydrochloride SR. Matzim LA Diltiazem is in a group of drugs called calcium channel blockers. Call your doctor at once if you have a serious side effect such as:       a red. nausea. fast or pounding heartbeat. To make sure you can safely take diltiazem. Before taking Diltiazem You should not use this medication if you are allergic to diltiazem.     . Less serious diltiazem side effects may include:      headache. swelling of your face. Diltiazem is used to treat hypertension (high blood pressure). swelling in your face or tongue. Dilacor XR. trouble breathing. Diltiazem Hydrochloride XT.Diltiazem Generic Name: diltiazem (dil TYE a zem) Brand names: Cardizem. Avoid drinking alcohol while taking diltiazem. cough. congestive heart failure. or  severe skin reaction -. tell your doctor if you have any of these other conditions: kidney disease. dizziness. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Diltzac. stuffy nose. low blood pressure. tired feeling. jaundice (yellowing of the skin or eyes). It works by relaxing the muscles of your heart and blood vessels. or if you are also taking clonidine (Catapres). Discuss the use of grapefruit products with your doctor. burning in your eyes. loss of appetite. or flushing (warmth.

cardiogenic shock. have been reported in 14. a resting heart rate below 60 bpm or severe hypotension (< 90/50 mm Hg). Other common side effects include bradycardia. Changes in vision may occur. the latter by reducing the duration of diastole. atrioventricular or intraventricular conduction times. headache and dizziness. Approved indication Ivabradine is indicated for the symptomatic treatment of chronic stable angina pectoris in patients with normal sinus rhythm who are intolerant to beta-blockers or in whom these agents are contraindicated. Precautions o General Ivabradine is contraindicated in patients with cardiac dysrhythmias. an important ionic current that usually controls spontaneous diastolic depolarisation in the sinus node and thereby regulates heart rate. 3 rd degree AV block. during which most myocardial perfusion occurs. a pure reduction in heart rate can reduce myocardial ischaemia and prevent angina pectoris. myocardial contractility or ventricular repolarisation. Ivabradine is not recommended for use in patients with liver dysfunction and is contraindicated in patients with severe liver dysfunction.e. class lll to lV heart failure. unstable angina pectoris. Patient information Ivabradine should be taken twice daily – in the morning and in the evening. enhanced brightness in the visual field. The tablets should be swallowed with a little water and taken with some food. AV 1 st degree heart block. those with a pacemaker. Major adverse effects Luminous phenomena (phosphenes) i. Therefore. acute coronary syndrome. . An elevated heart rate increases myocardial oxygen demand and limits tissue perfusion. ventricular extrasystoles. o Pregnancy and lactation Ivabradine is contraindicated for use during pregnancy and lactation.Coralan® (ivabradine) – The first selective and specific If inhibitor Mode of action Ivabradine is a heart rate lowering agent. but usually resolve with continued treatment. These effects usually resolve spontaneously during treatment.5% of patients. It acts by selective and specific inhibition of the cardiac pacemaker If current. The cardiac effects of ivabradine are specific to the sinus node and ivabradine has no effect on intra-atrial.

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