FINAL YEAR PROJECT 1

(Semester2, Academic Year 2007/2008)

Title :

Sintering Behaviour of Cerium-doped Hydroxyapatite Bioceramics
Prepared by:

KELVIN HOH CHEE WAI (ME075719)
Project Supervisor: Assoc. Prof. Ir. Dr. Ramesh Singh

Department of Mechanical Engineering Universiti Tenaga Nasional (UNITEN)

OBJECTIVE

To investigate the effects of adding small amounts of Cerium Oxide (CeO 2 ) on the sinterability of nanocrystalline HA powder.

METHODOLOGY
Literature Review Preparation of Cerium-doped HA powder Powder Characterization Body Preparation Consolidation Process Mechanical Testing & Evaluation Report preparation & presentation

FYP 1

FYP 2

INTRODUCTION
•What is Hydroxyapatite?
It is the most suitable ceramic material for hard tissue replacement implant from the point of view of Biocompatibility. It has the chemical similarity with the mineral portions of hard tissue. (e.g. Calcium + Phosphorus) Chemical formula:

Ca10(PO4)6(OH)2

•Why Hydroxyapatite is being developed?
Metallic materials have various problems to be used as implant. (e.g. negative tissue reaction, wear and corrosion.) Zirconia (ZrO2) and Alumina (Al2O3) belong to Bioinert materials.

Table 1 : Typical Properties of Bioceramics

The Limitation of Hydroxyapatite

How to improve the Hydroxyapatite?

Control of sintering temperature & atmosphere. Manipulation of processing parameters. Addition of additives (dopants) into the HA powder.

Ideal Sintering Additive (dopant)

Aid densification of HA without decomposition. No effect on Biocompatibility & Bioactive phases. Control of grain size. Improve the mechanical properties.

X-ray Diffractometer (XRD)
1250C

1400C

-TCP

1450C

TTCP -TCP

CaO

Scanning Electron Microscope (SEM)

ky

Y  O 

d

Hall-Petch Equation

Where, ky óo d óy

= = = =

material constant starting stress for dislocation movement grain diameter (m) Fracture strength

Fracture Toughness vs Porosity

Vickers Hardness vs Sintering Temperature

CONCLUSIONS
Hydroxyapatite is suitable for fabricating the artificial teeth & bone due to its excellent biocompatibility.  Improvement on Fracture Toughness & Young’s Modulus is needed.  Cerium was found that it decreases the crystal’s size of the HA.

Stoichiometric

The stoichiometric Ca/P ratio of HA Calcium Oxide (CaO) forms if Ca/P -TCP and -TCP forms (Tricalcium Phosphate)

: : :

1.67 >1.67 <1.67

Sign up to vote on this title
UsefulNot useful