Requirements in NCM 102 RLE

Submitted to: Ma am Cristina Salvador, RN, MAN Clinical Instructor

Submitted by: Angela Marie Ferrer BSN 2B

a new Swedish study finds." she said.000 took SSRIs during late pregnancy and about 17." she added. nearly 11. Most of these women were older and smoked. before we scare pregnant women not to treat their depression in pregnancy. Based on these data. the choice of substance is of less importance. 2012 THURSDAY. "It is important that. we ensure that the science overcomes its methodological limitations. Iceland." Dr. director of the Motherisk Program at The Hospital for Sick Children at the University of Toronto and author of an accompanying journal editorial. "Most notably. severe disease is associated with heart failure. non-medical treatment for depression during pregnancy should be considered." said lead researcher Dr." he said. The condition. Jan. "If possible.000 newborns. while their results show that untreated depression can also do it. said this finding does not prove that SSRIs cause persistent pulmonary hypertension. as risks for the specific SSRIs were of similar magnitude. researchers reported. "Infants born to women treated with SSRIs in late pregnancy had a twofold increased risk [of] their infants having persistent pulmonary hypertension. Finland. 12 online issue of the BMJ. Kieler said. For the study. Although rare." Koren said. Women taking SSRIs should be informed about the increased risk. known as persistent pulmonary hypertension. "The increased risk seemed to be a class effect of SSRIs. Helle Kieler. Jan 13. "For women where treatment with an SSRI is the only or best option. the authors have chosen SSRIs as the potential cause for persistent pulmonary hypertension. "we cannot yet conclude that use of SSRIs causes persistent pulmonary hypertension in some babies. Norway and Sweden.000 took them during early pregnancy. the investigators noted. The report was published in the Jan. Kieler's team collected data on more than 1 million births from 1996 and 2007 in Denmark. . head of the Centre for Pharmacoepidemiology at Karolinska University Hospital in Stockholm.Antidepressants While Pregnant Linked to Slight Risk of Lung Problem in Babies By Steven Reinberg HealthDay Reporter | HealthDay ± Fri." he said.Women who use antidepressants called selective serotonin-reuptake inhibitors such as Prozac and Celexa during pregnancy run a slight risk of having an infant with high blood pressure in the lungs. can lead to shortness of breath and difficulty breathing. but they should also be told that persistent pulmonary hypertension is a rare disease that affects fewer than two of 1. 12 (HealthDay News) -. Gideon Koren. Among the mothers.

Among the 54. the risk is not increased to the point where it would change the pattern of the way doctors are managing their pregnant women. the benefit of remaining on SSRI medication is important.html Reaction: ." she said.2 percent) suffered persistent pulmonary hypertension. but were not taking any medication." reference: http://news. Ilene Sosenko. Managing the depression is probably more important than worrying about the risk of persistent pulmonary citalopram (Celexa). more than 54. a professor of pediatrics and neonatology at the University of Miami School of Medicine. Fluvoxamine was rarely used and none of the children with persistent pulmonary hypertension were exposed to it. Dr. Other factors such as Cesarean delivery or low birth weight were not associated with persistent pulmonary hypertension. they added. the researchers noted.000 women who used SSRIs in early pregnancy. 33 babies (0. Kieler's group looked at the use of fluoxetine (Prozac). "Although there is a very small increased risk of persistent pulmonary hypertension. 32 babies (less than 0." she said.000 mothers who used an SSRI in late pregnancy. "From a clinical standpoint. Of the nearly 11. fluvoxamine (Luvox). Kieler's group found. "Depression can impact on how the mother eats or whether she takes other drugs or whether she gets her prenatal care. Of the more than 17.In addition. the risk remains extremely low. Another mothers who had previously been diagnosed with a mental problem but who did not take SSRIs during their pregnancy. paroxetine (Paxil)." she said.2 percent) were born with persistent pulmonary hypertension. said this study won't change clinical practice. sertraline (Zoloft) and escitalopram (Lexapro). they noted. 114 infants were born with persistent pulmonary hypertension. "The risk of persistent pulmonary hypertension is very low and even though there is a higher risk with SSRIs. Among the women taking SSRIs. Sosenko said.000 mothers had been previously diagnosed with mental problems. the researchers found.

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