Generic Name: Dynastat Brand name: Parecoxib Classification: Non-steroidal anti-inflammatory drugs.

Indication: IIndicated for the short-term treatment of postoperative pain in adults. Parecoxib has not been studied in patients under 18 years. Therefore, its use is not recommended in these patients. Action: NSAIDs inhibit cyclooxygenase (COX) enzymes, which are involved in the synthesis of prostaglandins and thereby reduce pain and inflammation. Oral NSAIDs are used post-operatively but when patients are unable to tolerate oral medications or require a faster onset of analgesia, parenteral administration may be preferred. Contraindications: You have or have had any medical conditions, especially the following: • • • • • • kidney or liver disease heart problems, heart heart attack stroke diabetes high cholesterol levels • • • conditions • Skin problems with symptoms such as swelling, blistering, peeling, high blood pressure, heart dehydration asthma or other allergic

failure or fluid retention

surgery, or other blood vessel disease

nose and genitals skin. being short of breath. • Peptic ulcer (ie stomach or duodenal ulcer). headache. raised red. a recent history of one. pain in the sleeplessness irritability sore throat inflammation and pain after a tooth skin rash. which may be accompanied by fever. sore throat. swelling. and looking pale • • • • unusual weight gain. vomiting. indigestion. swelling of a change in the amount or infection of any wounds chest pain or discomfort ankles or legs frequency of urine passed extraction itchy spots eyes. including hives. diarrhoea. mouth. heartburn. reddening or some other abnormality. diarrhoea. or have had peptic ulcers before. blistering and bleeding in the lips.itching. stiff neck. wind fever. lips. aching joints and muscles • other signs of allergic reaction such as wheezing. . sensitivity to light and vomiting • bleeding or bruising more easily than normal. Side Effects: • • • • • changes in blood pressure dizziness or light-headedness due to back pain a reduced sense of touch stomach upset including nausea chills. tongue or throat which may cause difficulty in swallowing or breathing • • slow heart beat severe or persistent headache. such as tiredness. mouth. low blood pressure (feeling sick). swelling of the face. blistering or peeling of the stomach. reddish or purplish blotches under the skin • signs of anaemia. cramps • • • • • • • • constipation.

it may hide some of the signs of an infection.When taken together these medicines can cause kidney problems. You are a smoker. Use of DYNASTAT during pregnancy is not recommended. including other Coxib medicines • any other substances. preservatives or dyes 2. followed every 6 to 12 hours by 20mg or 40mg as required to a maximum of 80mg per day Nursing responsibilities: 1. You currently have an infection. breastfeeding should be discontinued during treatment with DYNASTAT. If you are given DYNASTAT while you have an infection. You are pregnant or intend to become pregnant • May affect your developing baby if taken during pregnancy.Stock dose: 40mg by IM or IV injection. 4. 3. Therefore. angiotensin receptor antagonists and diuretics (also called fluid or water tablets). You are breastfeeding or intend to breastfeed • It is not known whether DYNASTAT passes into breast milk or whether your baby might be affected. stop or restrain from smoking 6. 5. . You are taking DYNASTAT together with any medicines used to treat high blood pressure and some other heart problems such as ACE inhibitors. You have any allergies to: • any other medicines including aspirin or other NSAID medicines. such as foods.

clumsiness. Pharmacologic: aminoglycosides Indication: Treatment of serious gram negative bacillary infection & infectious caused by staphylococci when Penicillin’s or other are less toxic drugs are contraindicated Action: Inhibits the protein synthesis bacteria at level of 30 S ribosome’s with bactericidal action Contraindications: Hypersensitivity. muscle twitching. or seizures. rash. a rash. closing of the throat. face. Products containing benzyl alcohol should be avoided in neonates.Generic Name: Aminoglycosides. Cross-sensitivity among aminoglycosides may occur Side Effects: • • • • an allergic reaction (shortness of breath. Most parenteral products contain bisulfates and should be avoided in patients with known intolerance. little or no urine. dizziness. hives. . Gentamicin Brand name: Cidomycin. or tongue. loss of appetite. increased thirst. or unsteadiness. decreased hearing or ringing in the ears. swelling of the lips. skin tingling. G-mycin. nausea or vomiting. • • • • • • numbness. Jenamicin Classification: Therapeutic: Anti-Infectives. or severe watery diarrhea and abdominal cramps. Gramycin. or fainting).

80 mg/ 50 ml. report to the physician early if it occur Resolution of signs and symptoms of superinfection if it occurs and if no response is seen within 3-5 days. Premixed injections: 40mg/50 ml. new cultures should be taken . 40 mg/ml. 100mg/ 80ml. 90mg/ 50 ml. 160mg/ 100ml. 70mg/ 50ml 70mg/ 100ml. 60mg/100ml. 100mg/ 100 ml. 180mg/ 100ml Nursing responsibilities: • • • • • Assess for the level of infection at the beginning at through out the administration of the medication Obtain specimen for culture and sensitivity before initiating therapy 1st dose may be given even with out the results Monitor intake and output and daily weight to assess hydration status and renal function Assess for the patient’s signs and symptoms of superinfection. 120mg/ 100ml. 90 mg/ 100ml. 60mg/ 50ml.Stock dose: Injection 10mg/ml. 80mg /100ml. 40mg/100 ml.

Generic Name: Naloxone Brand name: Narcan Classification: Therapeutic: antidotes. Management of refractory circulatory shock Action: competitively blocks the effects of opioids. nausea and vomiting Stock dose: Injection: 0. GI. ventricular fibrillation and ventricular tachycardia. hypotension. Side Effects: Hypertension. Therapeutic effects: Reversal of signs of opioid excess Contraindications: in patients known to be hypersensitive to naloxone hydrochloride or to any of the other ingredients in Narcan.02 mg/ml in combination with pentazocine Nursing responsibilities: . Pharmacologic: opioid antagonist Indication: Reversal of CNS depression and respiratory depression because of suspected opioid overdosage.4 mg/ml. including CNS and respiratory depression with out producing any agonist effects. Unlabeled uses: Narcotic induced pruritis. Neonatal injection: .

• Assess for signs and symptoms of opioid withdrawal.• Monitor vitals signs especially respiratory arte. Severity depends on dose of naloxone. and degree of physical dependence • Lack of significant improvement indicates that symptoms are caused by a disease process or other non-opioid CNS depressant not affected by naloxone • Dosages should be titrated carefully in postoperative patients to avoid interference with control of postoperative pain • Resuscitation equipment. ECG. vasopresor and mechanical ventilators should be available to supplement naloxone therapy as needed . Symptoms may occur within few minutes to 2 hours. pulse. and lvel of consciousness frequently for 3-4 hours after the expected peak of blood concentration. the opioid involved. rhythm and depth. oxygen.

sleep at the beginning of surgery. or glycerol. egg lecithin. soybean oil. Labor and delivery Side Effects: . Mechanism of action is unknown. Has no analgesic property. Produces amnesia. Propofol provides loss of awareness for short diagnostic tests and surgical procedures. Therapeutic: induction and maintenance of anesthesia Contraindications: Hypersensitive to propofol. It is given by trained anesthesia professionals in a controlled environment Action: short acting hypnotic. Propofol is for injection into a vein. and supplements other types of general anesthetics. and promotes relaxation and sleep or loss of consciousness.Generic Name: Propofol Brand name: Diprivan Classification: General anesthetics Indication: Propofol is a drug that reduces anxiety and tension.

Infections and subsequent dea6hs have been reported • May cause drowsiness or dizziness. and its effects generally wear off in just a few hours. or itching swelling or extreme pain at the injection site uncontrollable muscle spasm dizziness pain or irritation at the injection site Stock dose: Injection: 10mg/ml in 20-ml ampules. However. palpitations lightheadedness or fainting spells numbness or tingling in the hands or feet seizure (convulsion) skin rash.Side effects that you should report to your prescriber or health care professional as soon as possible: • • • • • • • • • • difficulty breathing. wheezing. or any other medicines for at least 24 hours after a dose of propofol. swelling of the throat fast heartbeat. Propofol is a very short-acting drug. • Avoid alcohol.and 100. flushing (redness).ml infusion vials Nursing responsibilities: • • Patient should be closely monitored following administration of propofol. Do not attempt to drive yourself home if you have received propofol for minor outpatient surgery or diagnostic tests. • Aseptic technique is essential. propofol may affect your ability to drive or operate machinery for several hours after use. 50. Solution is capable of rapid growth of bacteria contaminants. mood-altering drugs. Advice patients to request assistance prior to ambulation and transfer to avoid driving or any kind of activities that requires alertness until response to medication is known . unless approved by your prescriber or health care professional.

neuron sensory: feeling of heat. pruritis. They can be isolated or associated and from type: • • • • respiratory: cough. acid Ioxitalamique Brand name: Telebrix Classification: Diagnostic products or other therapeutic products Indication: • • • • Tomodensitometry Intravenous urography Digitized Angiography Angiocardiography (ventriculographie. distresses. rash cutaneous. agitation.Generic Name: Acid Ioxitalamique. palpebral edema. cutaneous: flush. localized or generalized urticaria. cephalgia. . digestive: nauseas. respiratory feeling of oppression . coronarography) Action: binds with the blood stream for better visualization of the parts of the organ that are being visualized by different diagnostics procedures Contraindications: Injection by way under-arachnoids Side Effects: Benign demonstrations of intolerance can occur precociously or tardily. vomiting.

The accidental extravasations of product of contrast apart from the being able to lead exceptionally to a cardiovascular collapse. cyanosis Neurological disorders: tetany. edema of the larynx. paleness. more rarely shock anaphylactic broncho spasm. vascular way are responsible for painful and inflammatory demonstrations local. • • • Cardiovascular disorders: disorders of the rate/rhythm. hypotension.More serious accidents can follow these minor signs or occur of start: • Reactions allergies: dyspnea. coma. crisis convulsive. pulmonary edema and exceptionally edema of Quince. Stock dose: 350 mg iode/ml inject able Solution by intravascular way Box of 1 Bottle (+ micro perfusion + syringe) of 50 ml Nursing responsibilities: • • • • Advice patient to increase fluid intake before and after the administration of the said medication to facilitate excretion Maintain proper hydration status Assess for any allergic reaction to seafood’s or iodine rich foods Advice the patient that discoloration on diffident secretions of the body may alter in color and it is just normal and if the said medication is gone into the body’s system it will go back to its original state • • Advice patient that alteration in taste sensation is normal and will go back as soon as the medication is excreted Nursing mothers should wait for 24 hours after contrast material injection before resuming breast-feeding. .

it is related to thiopental's anesthetic action and results in increased cerebral vascular resistance with a decrease in cerebral blood flow and cerebral blood volume. local anesthesia. and a scavenging of free oxygen radicals .Generic Name: Thiopental Sodium Brand name: Pentobrim. Various mechanisms of action have been proposed. or other causes Action: Ultra short-acting barbiturate anesthetics depress the central nervous system (CNS) to produce hypnosis and anesthesia without analgesia. and directly depressing excitability by increasing membrane conductance (an effect reversed by the GABA antagonist picrotoxin). However. The mechanism by which thiopental reduces intracranial pressure and protects the brain from cerebral ischemia and hypoxia is not completely understood. Pentothal Sodium Classification: Anesthetics General & Local Indication: Parenteral thiopental also indicated in the treatment of cerebral hypertension. and to control convulsive states during or following inhalation anesthesia. The exact mechanism by which barbiturate anesthetics produce general anesthesia is not completely understood. diminishing glutamate (GLU) responses. for narcoanalysis in the treatment of psychiatric disorders. in the treatment of cerebral ischemia and hypoxia. an inhibition of the brain stem neurogenic mechanism of vasoparalysis. and decreased cerebral metabolic rate for oxygen. it has been proposed that they act by enhancing responses to gamma-aminobutyric acid (GABA). thereby producing a net decrease in neuronal excitability to provide anesthetic action. a decrease in the functional activity of the brain. including a reduction of cerebral metabolic rate. However. a sealing effect on membranes.

Contraindications: Absence of suitable veins. about 1 mg per kg of body weight as required. 4 to 6 mg per kg of body weight. as a general guideline: Intravenous (intermittent). as a general guideline: Intravenous. however. 30 mg per kg of body weight For parenteral dosage form only • A test dose of 25 to 75 mg (1 to 3 mL of a 2.5 mg per kg of body weight may be used. patient reaction should be observed for at least 60 seconds. concentrations less than 2% in sterile water for injection should not be used because they cause hemolysis.4% concentration of thiopental in sterile water for injection is isotonic. In pediatric patients. Maintenance—Dosage must be individualized by physician. status asthmaticus. A 3. • • A 2 or 2. a test dose of 0.5% solution) may be administered to determine tolerance or unusual sensitivity to thiopental. porphyria Side Effects: Drowsiness. dependence with withdrawal side effects including seizures Stock dose: Rectal. tolerance.5% concentration of thiopental solution is used for intermittent intravenous administration. Nursing responsibilities: • Avoid alcohol intake at least 24 hours without advice of the health care professional • Inform patient that medication will decrease mental recall of the procedure . Children up to 15 years of age: • • • Induction—Dosage must be individualized by physician. however.

osteoarthritis. acute pain.• mood-altering drugs. Solution is capable of rapid growth of bacteria contaminants. Infections and subsequent dea6hs have been reported • May cause drowsiness or dizziness. Voltaren. anti-inflammatory agents Indication: Management of inflammatory disorder including: Rheumatoid arthritis. Advice patients to request assistance prior to ambulation and transfer to avoid driving or any kind of activities that requires alertness until response to medication is known Generic Name: diclofenac (dye KLOE fen ak) Brand name: Cataflam. Relief of mild to moderate pain of dysmenorrheal. or any other CNS depressant medicines for at least 24 hours without advice of the health care professional • Aseptic technique is essential. ankylosing spondylitis. Voltaren-XR Classification: nonopioid analgesics. Topical: treatment of actinic Kerasotes Action: inhibits prostaglandin synthesis. nonsteroidal. Therapeutic effects: suppression of pain and inflammation .

dizziness. on the skin. numbness. urinating less than usual or not at all. low fever. Stock dose: Diclofenac sodium delayed release (enteric coated) tablets: 25 mg. problems with vision or black. skin itching or rash. or Ringing in your ears. and red skin bruising. stomach pain. bloating. nervousness. clay-colored stools. dark urine. and headache with a severe blistering. blurred vision. fever. peeling. bloody. neck stiffness. rash. severe tingling. constipation. pain. chest pain. increased sensitivity to light. 75 mg. coughing up blood or vomit that looks like coffee grounds. In combination with: 200 mcg Misoprostol. mild heartburn or stomach pain. Active GI bleeding and ulcer disease Side Effects: • • • • • • • • • • • • • • • upset stomach. nausea. gas. shortness of breath. weakness. chills. swelling or rapid weight gain. and/or seizure (convulsions). 50 mg. or Fever. headache. diarrhea. loss of appetite. Diclofenac sodium extended-release tablets: 75 and 100 mg. Suppositories: 50 and 100 mg. headache. muscle weakness.Contraindications: Hypersensitivity to disclofenac or other components of formulation of Cross-sensitivity may occur with other NSAID’S including aspirin. Nursing responsibilities: . slurred speech. sore throat. or tarry stools. jaundice (yellowing of the skin or eyes). purple spots balance.

Do not double doses. Caution patient to avoid any kind of activities that requires alertness until response to medication is known . Use lowest effective does for shortest period of time • Instruct patient to take diclofen with afull galss of water and to remain in an uprigtyht posityion for 15-30 minutes afgter adminitration. and use this medication only for the indication prescribed.• Remember. • May cause drowsiness or dizziness. never share your medicines with others. • Take missed dose as soon as possible within 1-2 hours if taking once or twice a day or unless almost most of the time for the next dose if taking more than twice per day. • Administration of higher that the recommended dose does not provide more relief and effectiveness but may cause increased side effects. keep this and all other medicines out of the reach of children.