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Top 20 Global Products, 2010, Total Audited Markets

2010 rank
(US$)
Global Market
LIPITOR
PLAVIX
SERETIDE
NEXIUM
SEROQUEL
CRESTOR
ENBREL
REMICADE
HUMIRA
ZYPREXA
AVASTIN
SINGULAIR
ABILIFY
MABTHERA
LANTUS
ARICEPT
ACTOS
LOVENOX
HERCEPTIN
DIOVAN

0
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20

2010 Sales % Growth
(US$ MN) 2010 (LC$)
$ 791,449
$ 12,657
$
8,817
$
8,469
$
8,362
$
6,816
$
6,797
$
6,167
$
6,039
$
5,960
$
5,737
$
5,532
$
5,466
$
5,430
$
5,034
$
4,686
$
4,432
$
4,317
$
4,282
$
4,165
$
4,157

5.2
(6.2)
(3.4)
4.4
1.3
13.2
24.0
5.2
10.3
19.7
6.6
11.1
9.2
16.3
7.8
16.7
8.5
3.9
-5.3
6.7
3.5

2009 Sales % Growth
(US$ MN) 2009 (LC$)
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$

752,022
13,288
9,100
8,099
8,236
6,012
5,383
5,863
5,453
5,032
5,357
5,015
4,986
4,673
4,681
4,019
4,025
4,124
4,577
3,911
3,930

6.7
(6.2)
7.9
8.9
7.1
13.4
39.2
9.3
13.1
31.8
9.3
27.2
8.9
31.7
9.5
21.8
13.2
9.4
8.4
7.9
5.8

2008 Sales % Growth
(US$ MN) 2008 (LC$)
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$

727,067
13,646
8,657
7,697
7,828
5,376
3,942
5,521
4,919
3,941
5,026
4,009
4,639
3,574
4,404
3,406
3,559
3,757
4,362
3,772
3,678

5.1
(0.1)
16.8
7.3
8.3
15.0
30.9
8.6
14.9
43.6
(2.2)
40.2
3.9
30.6
15.4
27.2
16.1
8.7
9.4
11.6
10.2

2007 Sales % Growth
(US$ MN) 2007 (LC$)
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$

671,164
13,454
7,289
7,113
7,146
4,619
2,988
4,998
4,198
2,692
5,016
2,837
4,407
2,714
3,712
2,651
2,986
3,407
3,902
3,270
3,178

Source: IMS Health Midas, December 2010
US$: Sales and Rank are in US$ with quarterly exchange rates
LC$: Growth is in constant $ to normalize for exchange rate fluctuations
Growth rates in US$ are not recommended due to extreme fluctuations in the value of the dollar
Sales cover direct and indirect pharmaceutical channel wholesalers and manufacturers. The figures above include
prescription and certain over the counter data and represent manufacturer prices.

6.3
(2.4)
21.8
10.0
5.8
17.1
41.0
10.8
15.4
34.8
3.5
41.3
15.3
26.4
12.3
27.5
18.0
15.7
12.8
22.0
13.8

2006 Sales % Growth
(US$ MN) 2006 (LC$)
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$
$

609,614
13,458
5,751
6,254
6,607
3,875
2,081
4,404
3,564
1,928
4,697
1,981
3,763
2,130
3,213
2,016
2,482
2,939
3,332
2,572
2,741

6.8
4.4
(2.6)
10.4
17.3
18.9
57.5
17.2
21.4
50.3
0.4
104.8
18.2
33.2
19.5
31.7
13.8
21.0
12.4
79.5
12.7

marketing corporation and active ingredient) will be grouped together 6.7 2008 Sales % Growth (US$ MN) 2008 (LC$) $ 727.2 $ 752.067 5.2010 rank (US$) Global Market 2010 Sales % Growth (US$ MN) 2010 (LC$) 0 $ 791.3 2006 Sales % Growth (US$ MN) 2006 (LC$) $ 609.022 6.1 2007 Sales % Growth (US$ MN) 2007 (LC$) $ 671.164 Product names shown are IMS International Product names.8 .614 6. Products marketed around the world with different names or marketing companies are grouped together The names generally reflect the name in the country where the product was lauched first A match on two of three criteria (local brand name.449 2009 Sales % Growth (US$ MN) 2009 (LC$) 5.