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The Nerve Impulse

1. Match each of the terms in column B with the appropriate definition in column A

Column A

Column B

______1. term used to denote that a membrane potential is sitting at about -70 mV

a. threshold

______2. reversal of membrane potential due to influx of sodium ions

b. sodium

______3. major cation found outside the cell

c. potassium

______4. Minimal stimulus needed to elicit an action potential

d. resting membrane
potential

______5. period when cell membrane is totally insensitive to additional stimuli, regardless of the
stimulus force used.

e. absolute refractory
period

______6. Major cation found inside the cell

f. depolarization

2. Fill the blanks with the correct words or terms.
Neurons, as with other excitable cells of the body, have two major physiological properties:_________________________and
___________________. A neuron has a positive charge on the outer surface of the cell membrane due in part to the action of
an active transport system called the_____________________________________. This system moves___________________
out of the cell and _______________________into the cell. The inside of the cell membrane will be negative, not only due to
the active transport but also because of_____________________________, which remain negative due to intracellular PH and
keep the inside of the cell membrane negative.
3. Why don’t the terms depolarization and action potential mean the same thing? ___________________________________
_____________________________________________________________________________________________________
_____________________________________________________________________________________________________
4. What is the difference between membrane irritability and membrane conductivity?________________________________
_____________________________________________________________________________________________________
_____________________________________________________________________________________________________

_____________________________________________________________________________________________________ .

Explain the reason for your answer in question 10 above. what type of stimulus would you use and why? _____________________________________________________________________________________________________ _____________________________________________________________________________________________________ _____________________________________________________________________________________________________ 7.0 V to the threshold voltage and stimulate the nerve? _____________________________________________________________________________________________________ _____________________________________________________________________________________________________ _____________________________________________________________________________________________________ 6. Does the addition of ether to the nerve cause any permanent alteration in neural response?___________________________ _____________________________________________________________________________________________________ 10. Why does the addition of sodium chloride elicit an action potential?____________________________________________ _____________________________________________________________________________________________________ _____________________________________________________________________________________________________ Inhibiting a Nerve Impulse 8. If you were to spend a lot of time studying nerve physiology in the laboratory. What was the effect of ether on eliciting an action potential?__________________________________________________ _____________________________________________________________________________________________________ 9. What was the effect of lidocaine on eliciting an action potential?______________________________________________ _____________________________________________________________________________________________________ .Eliciting a Nerve Impulse 5. Why does the nerve action potential increase slightly when you add 1. What was the effect or curare on eliciting an action potential?_________________________________________________ _____________________________________________________________________________________________________ 11.____________________________________________________ _____________________________________________________________________________________________________ 12.

What is the relationship between size and of the nerve and conduction velocity?__________________________________ _____________________________________________________________________________________________________ _ _____________________________________________________________________________________________________ _ 14. __________________________________ _____________________________________________________________________________________________________ _ 16. _____________________________________________ _____________________________________________________________________________________________________ _____________________________________________________________________________________________________ _____________________________________________________________________________________________________ 17. Keeping your answer to question 13 in mind.Nerve Conduction Velocity 13. How does myelination affect nerve conduction velocity? Explain. If any of the nerves used were reversed in their placement on the stimulating and recording electrodes. how might you draw an analogy between the nerves in the human body and electrical wires? _____________________________________________________________________________________________________ _ _____________________________________________________________________________________________________ _ 15. would any differences be seen in conduction velocities? Explain. _____________________________________________________________________________________________________ _____________________________________________________________________________________________________ _____________________________________________________________________________________________________ . Hypothesize what type of animals would have the fastest conduction velocities.

_______________ . _______________ D. _______________ F. _______________ B. _______________ E. _______________ G. _______________ C.Name the structures. A.