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Kelompok Analgetik, NSAIDS, Obat Batuk dan Pilek, Anti Alergi dan Asma, Anestesi Obat untuk Penghilang

Rasa Sakit (Pain Killer) Nama Obat Acetaminophen (Tylenol) Aspirin Azapropazone (Rheumox) Butalbital (Fioricet, Fiorinal, Bancap, Twodyne) Butorphanol (Stadol) Celecoxib (Celebrex)) Codeine (in Tylenol #3, #4) Colchicine Diclofenac (Cataflam, Voltaren) Fentanyl (Sublimaze) Flurbiprofen (Ansaid, Froben, Ocufen) Hydrocodone (Lortab, Vicodin) Hydromorphone (Dilaudid) Ibuprofen (Advil, Nuprin, Motrin, Pediaprofen) AAP approved?* Approved Caution Approved Kategori Risiko Kehamilan** B C (1st, 2nd trim.) D (3rd trim.) Risiko Notes Menyusui** L1 L3 L2 2 1

NR Approved NR Approved Approved NR Approved NR NR NR Approved

D B (1st, 2nd trim.) D (3rd trim.) C C D B B B (1st, 2nd trim.) C (3rd trim.) B C B (1st, 2nd trim.) D (3rd trim.)

L3 L3 L2 L3 L4 L2 L2 L2 L3 L3 L1

3

4 5

Indomethacin (Indocin) Ketorolac (Toradol, Acular) Meperidine (Demerol)

Approved Approved

B (1st, 2nd trim.) D (3rd trim.) B (1st, 2nd trim.) D (3rd trim.) B B B B B B B B C

L3 L2 L2; L3 early 6 postpartum L3 L3 L2 L3; 9 L4 for chronic use NR L3 L2 L2 L2 11 12 L3 L3 L3 14 more 13 10 7 8

Approved

Methadone (Dolophine) Approved Morphine (Duramorph, Infumorph, Epimorph, MS Contin) Nalbuphine (Nubain) Naproxen (Anaprox, Naprosyn, Naproxen, Aleve) Nefopam (Acupan) Oxycodone (Tylox, Percodan,Oxycontin, Roxicet, Endocet, Roxiprin, Percocet) Pentosan polysulfate (Elmiron) Piroxicam (Feldene) Propoxyphene (Darvocet N, Propacet, Darvon) Rofecoxib (Vioxx) Secobarbital (Seconal) Tolmetin (Tolectin) Tramadol HCL (Ultram, Ultracet) Valdecoxib (Bextra) Approved NR Approved Approved NR NR Approved Approved

Withdrawn from the market Approved Approved NR D C C Withdrawn from the market

* Per the AAP Policy Statement The Transfer of Drugs and Other Chemicals Into Human Milk, revised September 2001.

. Lactation Risk Categories Pregnancy Risk Categories • • • • • • • • • • L1 (safest) L2 (safer) L3 (moderately safe) L4 (possibly hazardous) L5 (contraindicated) A (controlled studies show no risk) B (no evidence of risk in humans) C (risk cannot be ruled out) D (positive evidence of risk) X (contraindicated in pregnancy) NR: Not Reviewed. • ** Per Medications’ and Mothers’ Milk by Thomas Hale. This drug has not yet been reviewed by Hale.• • Approved: (Table 6) Maternal Medication Usually Compatible With Breastfeeding Caution: (Table 5) Drugs That Have Been Associated With Significant Effects on Some Nursing Infants and Should Be Given to Nursing Mothers With Caution NR: Not Reviewed. 1. This drug has not yet been reviewed by the AAP. Aspirin use is discouraged in children and nursing mothers due to the risk of Reye’s syndrome and internal bleeding. PhD (2004 edition).

caffeine. poor sucking reflex. kidneys and GI tract. 9. Per Hale. respiratory depression. observe infant for sedation. Percocet also contain acetaminophen. Fioricet (Fiorinal. apnea. observe infant for sedation. Per Hale. Per Hale. 12. and butalbital. 8. 3. Non-steroidal anti-inflammatory analgesics (NSAIDs) [more] Nama Generik Kategori Nama Dagang AAP Risiko Risiko approved?* Kehamilan** Menyusui** Approved Approved NR L2 Azapropazone Rheumox (apazone) Dipyrone (banned in the US & UK) Flufenamic acid - Approved - NR . constipation. Two-dyne) contains acetaminaphen or asprin. Endocet. higher doses may result in infant sedation. Per Hale. infrequent or occasional use is not necessarily incompatible with breastfeeding. short-term. 5. 11. Roxiprin. 6. Per Hale. baby should be observed for sedation. Per Hale. and neurobehavioral delay in infants. Bancap. withdrawal syndrome. 7. observe infant for GI cramping. Meperidine use during labor or early postpartum has been associated with sedation. Per Hale. use of frequent. Per Hale. 10. observe infant for sedation. should be used with caution due to its long half-life and its effect on baby’s cardiovascular system. diarrhea.2. Per Hale. Hale suggests weakened or premature infants be observed for sedation and apnea. observe infant for sedation. observe infant for sedation. Roxicet. 13. Per Hale. 14. higher dose may result in infant sedation. addiction. 4. Per Hale. distress. Hale suggests newborns be observed for sedation.

Ibuprofen Advil.) D (3rd trim.) D (3rd trim.) B (1st. Orasone Approved Approved Approved C C C L2 L2 L2 Obat Asma Dyphylline Terbutaline Theophylline Dilor.) D (3rd trim. Approved Motrin. Theo-Dur . Naprosyn.) B (1st. 2nd L1 trim. Dyphylline Bricanyl. Aleve Butazolidine Feldene Profenal Tolectin Approved Approved Approved Approved Approved Approved Approved Methylprednisolone Solu-Medrol. Meticorten. Lufyllin. Pediaprofin B (1st. Naproxen. 2nd L2 trim. Nuprin. 2nd L3 trim. Ponstel Anaprox. Acular Ponstan. Approved Quibron. methylprednisolone] Medrol Prednisolone Prednisone Deltasone.) B B C NR L3 L4 (for chronic use) NR L2 NR L3 [contents] Indomethacin Indocin Approved Ketorolac Mefenamic acid Naproxen Phenylbutazone Piroxicam Suprofen Tolmetin Steroid Toradol. [ high dosage Depo-Medrol. Brethine Approved Approved C B C [contents] L3 L2 L3 Aminophylline.

) Approved Approved C B L3 L2 L2 L3 (if used early postpartum) L3 L3 L2 L3 Meperidine Demerol Approved B Methadone Morphine Propoxyphene Dolophine Morphine Darvocet N. Propacet. Darvon Approved Approved Approved B B C Obat Batuk Nama Obat Codeine Dextromethorphan Guaifenesin AAP approved?* yes Risiko Menyusui** L3 (moderately safe) not L1 (safest) reviewed not L2 (safer) reviewed AAP approved?* Dekongestan (Obat Pilek) Nama Obat Phenylephrine Pseudoephedrine (Sudafed. #4 Sublimaze B (1st. Actifed) Risiko Menyusui** not L3 (moderately safe) reviewed yes L3 (moderately safe) for acute use L4 (possibly hazardous) for chronic use due to potential for decreasing milk supply * Per the AAP Policy Statement The Transfer of Drugs and Other Chemicals . 2nd Approved trim.Analgetik Narkotik [more] Butorphanol Codeine Fentanyl Stadol Tylenol #3.) D (3rd trim.

Beclovent.Into Human Milk. PhD (2006 edition) Nasal Sprays (Spray Hidung) Nama Obat Beclomethasone (Vanceril. ** Per Medications’ and Mothers’ Milk by Thomas Hale. Vancenase) Cromlyn sodium (Nasalcrom) Fluticasone (Flonase) Mometasone (Nasonex) Phenylephrine (in some forms of Sinex and Neo-Synephrine) Triamcinolone Acetonide (Nasacort) AAP approved?* not L2 (safer) reviewed not L1 (safest) reviewed not L3 (moderately safe) reviewed not L3 (moderately safe) reviewed not L3 (moderately safe) reviewed not L3 (moderately safe) reviewed AAP approved?* Risiko Menyusui** Antihistamin (Anti Alergi) Nama Obat Brompheniramine Chlorpheniramine (Chlor-Trimeton) CTM Cetirizine (Zyrtec) Dexbrompheniramine maleate with d-isoephedrine Diphenhydramine (Benadryl) Risiko Menyusui** not L3 (moderately safe) reviewed not L3 (moderately safe) reviewed not L2 (safer) reviewed yes not reviewed not L2 (safer) reviewed . revised September 2001. Beconase.

L1 (safest) yes Actifed) * Per the AAP Policy Statement The Transfer of Drugs and Other Chemicals Into Human Milk. revised September 2001. PhD (2002 edition) Obat Anestesi Nama Obat Local anesthetics Articaine (Septocaine) Bupivacaine (Marcaine) Lidocaine (Xylocaine) Mepivacaine (Carbocaine. ** Per Medications’ and Mothers’ Milk by Thomas Hale.Doxylamine Fexofenadine (Allegra) Loratadine (Claritin) not L4 (possibly hazardous) reviewed yes yes L3 (moderately safe) L2 (safer) Terfenadine not reviewed yes (Seldane) Triprolidine (Actidil. Polocaine) Procaine HCL (Novocaine) General anesthetics Halothane (Fluothane) Isoflurane (Forane) Ketamine Methohexital (Brevital) Nitrous oxide Sevoflurane (Ultane) Thiopental (Pentothal) Approved NR NR Approved NR NR Approved C B B C L2 NR NR L3 L3 L3 L3 more 1 more NR NR Approved NR NR C C C C NR L2 L2 L3 L3 more more AAP Kategori Risiko Risiko Notes approved?* Kehamilan** Menyusui** .

Other medications often used during anesthesia Sedatives Diazepam (Valium) Concern D Midazolam (Versed) Propofol (Diprivan) Triazolam (Halcion) Narcotic Analgesics Alfentanil (Alfenta) Fentanyl (Sublimaze) Hydromorphone (Dilaudid) Morphine Reversal Medication Flumazenil (Romazicon) Naloxone (Narcan) Steroids Decadron (Dexamethasone) Stimulants Epinephrine (Adrenaline) Anti-nausea Promethazine (Phenergan) NR C NR C NR C NR NR C C NR Approved NR Approved C B C B Concern NR NR D B X L3. • • • Approved: (Table 6) Maternal Medication Usually Compatible With Breastfeeding Concern: (Table 4) Drugs for Which the Effect on Nursing Infants Is Unknown but May Be of Concern Caution: (Table 5) Drugs That Have Been Associated With Significant Effects on Some Nursing Infants and Should Be Given to Nursing Mothers With Caution . revised September 2001. L4 for chronic use L3 L2 L3 L2 L2 L3 L3 NR NR NR L1 L2 3 more 2 more * Per the AAP Policy Statement The Transfer of Drugs and Other Chemicals Into Human Milk.

3. ** Per Medications’ and Mothers’ Milk by Thomas Hale. Naloxone (Narcan) is used directly in newborns and children. More here. so the majority of the medication is out of the body (and milk) very quickly. 2. Isoflurane (Forane) is used for c-sections and directly in newborns. Lactation Risk Categories Pregnancy Risk Categories • • • • • • • • • • L1 (safest) L2 (safer) L3 (moderately safe) L4 (possibly hazardous) L5 (contraindicated) A (controlled studies show no risk) B (no evidence of risk in humans) C (risk cannot be ruled out) D (positive evidence of risk) X (contraindicated in pregnancy) NR: Not Reviewed. 4. as there are many . PhD (2004 edition). Always check the active ingredients. Induction of and recovery from isoflurane anesthesia are rapid. This drug has not yet been reviewed by Hale. 1. This drug has not yet been reviewed by the AAP.• NR: Not Reviewed. Many forms of Robitussin. Delsym and Benylin are considered compatible with breastfeeding. Flumazenil (Romazicon) is used directly in children aged 12 months and up.

Obat jantung & Hipertensi. Kontrasepsi. Fortaz. Kefzol Claforan Mefoxin Cefzil [contents] Approved Approved Approved Approved Approved Approved Approved B B B B B B C B B C B L2 L1 L1 L2 L1 L1 L1 L2 L3 L3 L1 Ceftazidime. Vitamin.versions. Antivirus. Amoxil Azactam Ultracef. dll Nama Generik Antasida Cimetidine (Antacid) Cisapride (GI tract stimulant) Nama Dagang Kategori AAP Risiko Risiko approved?* Kehamilan** Menyusui** [contents] Tagamet Propulsid Approved Approved Approved B C L2 L1 L2 Domperidone (used for nausea & vomiting. stimulates Motilum lactation) [more] Antibiotika Amoxicillin Aztreonam Cefadroxil Cefazolin Cefotaxime Cefoxitin Cefprozil Ceftazidime Ceftriaxone Ciprofloxacin [more] Clindamycin Larotid. Antijamur. Kelompok Antasida. Approved Taxidime Rocephin Cipro Cleocin Approved Approved Approved . Duricef Ancef. Antibiotik.

Timentin Trimethoprim/sulfamethoxazol Proloprim. Sulfisoxazole AzoGantrisin Achromycin. Terramycin Ticarcillin.Erythromycin Fleroxacin Gentamicin Kanamycin Moxalactam Nitrofurantoin Ofloxacin Penicillin Streptomycin Sulbactam E-Mycin. Ery-tab. ERYC. Panwarfin Approved Approved D L2 NR [contents] Approved Approved C C L4 L2 . Kantrex Moxam Macrobid Floxin - Approved Approved Approved Approved Approved Approved Approved Approved B C D B C B D C D B C L1 L3 early postnatal NR L2 L2 NR L2 L2 L1 L3 NR L2 L2 L1 L3 [contents] Streptomycin Approved Approved Approved Approved Approved Approved Gantrisin. Epitol Zarontin Coumadin. Ticarcillin Ticar. Ilosone Garamycin Kebecil. e Trimpex Antikoagulan Bishydroxycoumarin (dicumarol) Warfarin Antikonvulsan (Anti kejang) Carbamazepine Ethosuximide Tegretol. Tetracycline Sumycin.

Hormon Ridaura. Nizoral Zovirax Alferon N. Lunelle injection. Ovral. Seasonale. Approved Solganal Estradiol Approved X Clogestone Approved - Contraceptive pill with estrogen/progesterone Approved X L3 (may interfere with milk production) . Norinyl. L3 (may interfere with milk production) NR L2 Arthritis meds (see also: pain meds) Gold salts Kontrasepsi. Depakote Diflucan Nizoral Shampoo. Norlestin. Menest Preven. Ortho-Evra patch. OrthoNovum.Magnesium sulfate Phenytoin Valproic acid Anti Jamur Fluconazole [more] Ketoconazole Antivirus Acyclovir [more] Interferon-alpha [more] Epsom salt Dilantin Depakene. Interferon Alpha Approved Approved Approved B D D L1 L2 L2 [contents] Approved Approved C C L2 L2 [contents] Approved Approved C C L2 [contents] C L5 [contents] Estratab. Myochrysine. etc. Permarin.

Plan Approved B Provera. Prometrium Approved X L2 L1 L4 (if used first 3 days postpartum) L2 L3 [contents] Medroxyprogesterone D Norethynodrel Progesterone Obat Diabetes Approved Approved X - Note: Insulin has not been reviewed by the AAP.Levonorgestrel Norplant. Pepto Diarrhea Control. Cycrin Enovid Crinone. due to the association of salicylates with Reyes syndrome in children. Kaopectate II Caplets. Tolbutamide Approved D L3 Orinase Obat Diare [contents] Imodium. Immodium Advanced ** Note: Pepto-Bismol & Kaopectate (bismuth subsalicylate is the active ingredient in both) are not recommended for routine use by nursing moms. DepoProvera. Diamox Naturetin Hydrodiuril Approved Approved Approved C D D [contents] L2 L4 (may inhibit lactation) L3 . Lactation risk category = L1. [more] Diuretik (Peluruh Kencing) Acetazolamide Bendroflumethiazide Chlorothiazide Dazamide. Pregnancy risk category = B. Mirena. Oramide. Maalox Loperamide Antidiarrheal Approved B L2 Caplets.

Obat Jantung Norpace. Lopressor C Enalapril/Enalapril Maleate Hydralazine Labetalol Methyldopa Metoprolol C (1st trim.) Approved D (2nd. Quinidex Approved Approved Approved Approved Approved C C B C C L2 L3 L2 L3 L2 Capoten Approved D L3 (if used after 30 days) L3 Diltiazem/Diltiazem HCL Cardizem Sr. Oretic Aldactone Approved Approved Approved D D D L3 L2 L2 [contents] Motilum Approved - L1 [contents] Anti Hipertensi. Cardizem CD Vasotec Apresoline Trandate. Approved Diltiazem. Napamide Tambocor Mexitil Pronestyl.Chlorthalidone Hydrochlorothiazide (HCT) Spironolactone Anti Muntah [more] Domperidone Anti aritmia Disopyramide Flecainide Mexiletine Procainamide Quinidine Anti Hipertensi Captopril Hygroton Hydrodiuril. Normodyne Aldomet Toprol XL. Procan Quinaglute. 3rd L2 trim.) Approved Approved Approved Approved C C C B L2 L2 L2 L3 . Esidrix. Dilacor-XR.

Lanoxicaps Epsom salt Aralen. Minodyl. Trasicor Inderol Betapace Blocadren Calan. Rogaine Corgard. Procardia Apsolox. Covera-HS Lanoxin. Novochloroquine Plaquenil Daraprim Quinamm Approved Approved Approved Approved Approved Approved Approved Approved C C C C B C C L2 (topically) L3 (orally) L4 L2 NR L2 L3 L2 L2 Approved C L2 [contents] Laksan (Pelancar BAB) [more] Cascara/Cascara Sagrada Danthron Magnesium sulfate Senna Obat malaria Chloroquine Hydroxychloroquine Pyrimethamine Quinine Approved Approved Approved Approved C C C D Approved Approved Approved Approved C B - L3 NR L1 L3 [contents] L3 L2 L4 L2 .Minoxidil Nadolol Nifedipine Oxprenolol Propranolol Sotalol Timolol Verapamil Cardiac stimulants Digoxin Loniten. SlowTrasicor. Isoptin. Nadolol Adalat.

Seconal .Medical Testing [more] Diatrizoate Fluorescein Gadopentetic (Gadolinium) Iohexol Iopanoic acid Metrizamide Metrizoate Obat Migren [more] Sumatriptan Obat Sedativ [more] Chloral hydrate Aquachloral. Levo-T. Thyroid. Approved Noctec Approved Approved Approved C D D Imitrex Approved C Omnipaque Telepaque Amipaque Isopaque Approved Approved Approved Approved Approved Approved Approved C C B D B B [contents] NR L3 L2 L2 L2 L2 L2 [contents] L3 [contents] L3 NR L5 L3 [contents] Ambien Approved B L3 [contents] Approved Approved Approved Approved Approved D D D A L3 L2 NR L1 L3 Methyprylon (withdrawn from use in US & Canada) Bromide Secobarbital Obat Tidur Zolpidem/Zolpidem Tartrate Obat Anti Tiroid [more] Carbimazole Methimazole (active metabolite Tapazole of carbimazole) Propylthiouracil Thiouracil Levothyroxine PTU Synthroid. Levothroid.

Laniazid Rifadin.Levoxyl Obat TBC Cycloserine Ethambutol Isoniazid Rifampin VITAMIN [more] B-1 (thiamin) B-12 (Cyanocobalamin) Approved Approved A L1 L2. L4 in high doses (may inhibit lactation) L3 (do not overdose) Seromycin Ethambutol.) C (3rd trim. Myambutol INH. vitamin (Phytonadione) Riboflavin/B2 Lain-lain Acitretin (Anti-psoriasis) Alcohol/Ethanol [more] Allopurinol Antimony Atropine (Anticholinergic. drying agent) Approved Approved Approved A (1st.) C A L1 L1 [contents] Soriatane Zyloprim. vitamin Calciferol. Rimactane Approved Approved Approved Approved C B C C L2 L3 L2 [contents] NR [contents] L3 B-6 (pyridoxine) - Approved A D. 2nd L1 trim. Atropine Approved Approved Approved Approved Approved D C C L3 L2 NR L3 NR . Delta-d - Approved A Folic acid K-1. Lopurin Belladonna.

Atrofen Vivarin.Azapropazone/apazone (Antirheumatic) Baclofen (muscle relaxant) Barbiturate Caffeine [more] Rheumox Lioresal. in a vaginal douche) Ivermectin (Antiparasitic) Nalidixic acid (Urinary Antiinfective) Norsteroids Pyridostigmine (Muscle stimulant) Mectizan NegGram - Mestinon. eg. DDS Plaquenil - Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved Approved C B D C C C B C C D L2 L2 NR L2 NR NR L4 L4 L2 NR NR NR L3 L4 NR L2 L3 NR L3 Carbetocin (Antihemorrhagic) Duratocin Chloroform Cisplatin (Anti-cancer) Dapsone (Antileprosy) Hydroxychloroquine (Antirheumatic. Regonol Transderm Scopolamine (Motion sickness) Scope Sulfapyridine Timolol (glaucoma med) Dagenan Blocadren * Per the AAP Policy Statement The Transfer of Drugs and Other Chemicals Into Human Milk. NoDoz. Coffee Platinol Avlosulfon. lupus) Iodides Iodine Iodine (povidone-iodine. • • Approved: (Table 6) Maternal Medication Usually Compatible With Breastfeeding Caution: (Table 5) Drugs That Have Been Associated With Significant . revised September 2001.

This drug has not yet been reviewed by the AAP. This drug has not yet been reviewed by Hale . Lactation Risk Categories Pregnancy Risk Categories • • • • • • • • • • L1 (safest) L2 (safer) L3 (moderately safe) L4 (possibly hazardous) L5 (contraindicated) A (controlled studies show no risk) B (no evidence of risk in humans) C (risk cannot be ruled out) D (positive evidence of risk) X (contraindicated in pregnancy) NR: Not Reviewed. PhD (2004 edition).Effects on Some Nursing Infants and Should Be Given to Nursing Mothers With Caution • NR: Not Reviewed. ** Per Medications’ and Mothers’ Milk by Thomas Hale.