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TEST PAPER FOR GPAT/NIPER-JEE-2012 TEST No.-1 (GENERAL) PHARMA WORLD CLASSES SAGAR MP Q.

1 what is the drug (a) a chemical substance of known structure, mainly a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a biological effect. (b) a chemical substance of known structure, other than a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a new biological function . (c) a chemical substance of known structure, other than a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a biological effect. (d) a chemical substance of known structure, mainly a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a new biological function. Q.2 Drug bind to receptor, Assertion - Produce their response: Region-Due to efficacy (a) Assertion is wrong& region is true (b) Assertion is true & region is wrong (c) both wrong Q.3 Spare receptor is (a) Fallow occupation concept (b) Not fallow occupation concept (c) Not fallow two step model (d) none (d) both true

Q.4 Target proteins on which drug act is (a) Receptor (b) enzymes (c) carriers (d) all

Q.5 Hill-Langmuir equation described the (a) Quantitative aspects of drug-receptor interactions

(b) Qualitative aspects of drug-receptor interactions (c) Quantitative aspects of drug-drug interactions (d) Qualitative aspects of drug-drug interactions Q.6. Correct for Binding of drugs to receptors (a)Binding of drugs to receptors necessarily obeys the Law of Mass Action. (b)The higher the affinity of the drug for the receptor, the lower the concentration at which it produces a given level of occupancy. (c)The same principles apply when two or more drugs compete for the same receptors; each has the effect of reducing the apparent affinity for the other. (d) all Q.7. Tetrodotoxin is(a) Voltage-gated sodium channels modulator (b) Voltage-gated sodium channels blocker (c) Voltage-gated sodium channels agonist (d) Voltage-gated sodium channels antagonist Q.8. choose the correct statement for the GPCRs (a) Membrane location (b) Effectors is only ion channel (c) Effectors is only enzyme (d) all Q.9 Type 3 receptor structures is (a) Oligomeric assembly of subunits surrounding central pore (b) Monomeric dimericor structure comprising seven transmembrane helices (c) Single transmembrane helix linking extracellular receptor domain to intracellular kinase domain (d) Monomeric structure with separate receptor- and DNA-binding domains Q.10. A person suffer from excessive lipolysis when he take mistakenly a poison

Assertion- Poison is pertussis and cholera toxin Region- Prevent inactivation of GPCRs (a) Assertion is wrong & region is true (b) Assertion is true & region is wrong (c) Both wrong (d) both true Q.11 Intra Cellular Release of Ca++ ion increased by the (a) PLC (b) DAG (c) IP3 (d) IP4 Q.12. what is the role of IP4 Formed from IP3 during PI cycle(a) Absolutely faccillate Ca++ ion entry via plasma membrane (b) unclear but may faccillate Ca++ ion entry via plasma membrane (c) Activate PKa (d) Inactivate Pka

Q.13 Secondary messengers is except (a) cGMP (b) cAMP (c) IP3 (d) PLC

Q.14. A drug which pka is 3.4 then rate of reabsorption of drug from renal tuble is(a) High (b) low (c) may be high or low (d) not predict

Q.15 Presystemic Metabolism also known as (a) First pass metabolism (c) phase 2 (b) phase 1 (d)none

Q.16 N-acetyl-p-benzoquinone imine is (a) non toxic metabolite of acetaminophen ( b) toxic prodrug of acetaminophen (c) toxic metabolite of acetaminophen (d) none Q.17 What is the unit of Michalies menten constant (a) no unit (b) amount unit

(c) concentration unit (d) a&b Q.18. when clearance is constant , the rate of drug elimination is -----------------proportional to drug concentration. (a) indirectly (b) directly (c) not depend (d) none Q.19 Drug concentrations are measured in plasma at 2-hour intervals following drug administration. The semilogarithmic plot of plasma concentration (Cp) versus time appears to indicate that the drug is eliminated from a single compartment by a first-order process with k = 0.173 hr–1) then half life of drug is (a) 240 min (b) 180 min (c) 120 min (d) 60 min Q.20 Here B is(a) agonist (c) Inverse agonist (b) partial agonist (d) antagonist

Q.21 Phase 2 clinical trials investigate the (a) safety (b) efficacy (c) verify efficacy (d) Obtain additional data following approval Q.22 All of the following are capable of initiating a signal transduction process EXCEPT (A) Combination of an agonist with its receptor (B) Combination of an antagonist with its receptor (C) Combination of a neurotransmitter with its receptor (D) Combination of a hormone with its receptor Q.23. Potency is determined by (A) Affinity alone (B) Efficacy alone (C) Affinity and efficacy (D) Efficacy and intrinsic activity Q.24. Following oral administration, a drug is absorbed into the body, wherein it can exert its action. For a drug given orally, the primary site of drug absorption is:

(A) The esophagus

(B) The stomach

(C) The upper portion of the small intestine (D) The large intestine Q.25.The body has developed defense mechanisms that reduce the amount of foreign chemicals, such as drugs, that enter the body. One of the more prominent of these mechanisms is an efflux transport system that pumps some drugs back into the intestinal lumen following absorption into the enterocytes and that is responsible for the lack of complete absorption of some drugs.This efflux transport system is: (A) Facilitated diffusion (B) P glycoprotein (C) Cytochrome P450 3A (D) Pinocytosis Q.27. Reaction is(A) Phase 1 (B) Phase 2 (C) Phase 3 (D) Phase 4 Q.28. Which of the following CYP enzymes is associated with metabolism of the greatest number of drugs and thus most likely to be involved in drug–drug interactions? (A) CYP3A4 (B) CYP2C9 (C) CYP2D6 (D) CYP2E1 Q.29. Frequently it is useful to consider the overall exposure of a person to a drug during the dosing interval. Which of the following pharmacokinetic parameters defines the exposure of a person to a drug? (A) Cmax (B) Tmax (C) AUC (D) Half-life

Q.30 Agonist pleotropy shown by the(a) M- Receptor (c) GABAB - Receptor (b) D2- Receptor (d) all

Q.31 All are GPCRS EXCEPT(a) 5-HT3- Receptor (c) Chemokine – Receptor (b) PGS - Receptor (d) Opiod- Receptor

40 Albumin is the - .32.35 Drug which produce opposite effect to agonist is called(a) Antagonist (c) Invese agonist (b) Partial agonist (d) Blocker Q.confermation change---. cAMP pathway starts with the(a)Activation of adenyl cyclase (b) Activation of protein kinase (c) Exchange of GDP with GTP in α – Units of G-protein (d) Exchange of ATP with ADP in α – Units of G-protein Q.38 Intrinsic activity for DMCM is(a) 0----(-1) (b) 0-----(+1) (c) 0 (d) 1 Q.37 Occupation of receptor is governed by the(a) Affinity (b) Intrinsic activity (c) Confermation chages (d) all Q.Transducer steps (c) Binding to receptor----.chemical change---.36 Iproniazid is the(a) Antitubercular drug (c) Anticancer drug (b) MOA-A inhibitors (d) Antileprotic drug Q.Q.34 Blood Glycogen rises when(a) cAMP increases (b) cAMP Decreases (c) IP3/ DAG increase (d) A&C Q.Transducer steps ----response--.39 Correct sequence by which the drug work(a) Binding to receptor----.confermation change ----response---.Transducer steps ----response (b) Binding to receptor----.confermation change (d) Binding to receptor----.Transducer steps ----response Q.

during the testing of urine.44 Which of the following enzyme responsible for the conversion of the codeine to morphine and this is inhibited by (a) CYP2E1.Astemizole (d) CYP2C8/9 . Cispride (b) CYP2D6.43 Find the volume of distribution of drug if plasma concentration of drug is 50 Mg/L and the totel drug in body is 100Mg (a) 2L (b) 20ML (c) 2000ML (d) 50ML Q.42 A patient take combination of aspirin and ciprofloxacin. the urine was found alkaline. which is responsible for the (a) Inhibition of CYP1A isoenzyme (b) Inhibition of CYP3A isoenzyme (c) Induction of CYP1A isoenzyme (d) Induction of CYP2B1 isoenzyme Q.45 Benzopyren found in cigratte smoke .46 A doctor have prescribed paracetamol to the patient . in this condition which drug is back diffuse in the kidney tubules (a) Aspirin (b) Ciprofioxacin (c) both (d) none Q. Diltiazim Q. Quinidine (c) CYP2C19 .41 Choose incorrect statement when drug is given by oral route (a) Slower action not suitable for emergency (b) Streptomycin is not absorbed by oral route (c) Cannot used for uncooperative patient (d) None Q. but by mistak patient take enzyme inducer with them. what would happened (a) Increase intensity of response (b) Increase duration of action .(a) Silent receptor C (b) nuclear receptor (c) Protien channel (d) A& Q.

Which of the following statement is true(a)Determination of pKa performed by spectral shift or visible spectroscopy (b)Unionized form is greatly absorbed than the ionized form (c)Drug with low pKa value.Vmax decreases (b) Km constant .49 Choose correct one for the non equilibrium type enzyme inhibition (a) Km increase .Flavouring agent.47 Probenacid prolong the duration of action of penicillin and ampicilline by (a) By reducing rate of metabolism binding (b) By increasing plasma protein (c) By prolonging absorption from absorption site (d) By reducing rate of excretion Q.(c) Toxicity (d) both a & b Q. who is used in the formulation of oral liquids. Vmax decrease (c) Km decrease .51.48 Which of the following is example of non competitive inhibitors (a) Physostigmine (c) Theophylline (b) Allopurinol (d) Carbidopa Q.Vmax increase Q. Vmax constant (d) Km decrease .52. gives the bitter test(P)Wild Cherry(Q)Liquorice (R)Mint(S)Vanilla (a)PQ (b) RS (c)PR (d)QS (b) Aspirin & paracetmol (d) Nitrous acid & Ether .unionized form is present in the stomach but ionized in the intestine (d)All Q.50Choose correct example for supra additive combination (a) Acetylcholine & Physostigmine (c) Ephedrine & Theophylline Q.

Function of tonocity modifier for the parenterals(a)Minimize tissue damaze and ↓ irritation cells (c)Prevent electrolyte imbalance (d)All (b)↓hemolysis of blood .Sterile water for injection is(a)Not contain any antmicrobial agent free (c)Filled in single dose container true (b)Must be pyrogen (d)All statement are Q.Ascorbic acid is an antioxidant functioning (P)Reducing agent (S)Chelates (a)PQ (b) RS (Q)Oxidising agent (c)PR (d)QS (R)Synergistic Q.Q.53.Most commonly used non aquous vehicle for sterile product is (a)Corn oil oil (b)Almond oil (c)Peanut oil (d)Sesame Q.56.54.57.Which statement is false about the ASPARTAME (a)200 times more sweet than sucrose (b)No bitter after test (c)High water solubility and stable at wide pH range (d)Not recomonded for the pregnant or lacting woman Q.55.

Polyoxyethylene sorbiton is the example of a surfactant which is(a)Non ionic (c)Anionic (b)Cationic (d)Amholytic Q.the correct scheme of the addition of emulsifiers(a)Span→tween (b)Tween→span (c)Both (d) None Q.60. Organ cultures d.Q. All the above Q.Which of the following statement is true about the MC(a)Soluble in hot water but insoluble in cold water (b)Soluble in cold water but insoluble in hot water (c)Insoluble in all conditions (d)Highly soluble in organic solvents Q.62.59.61.For the preparation of W/O/W type multiple emulsion. Monoclonal antibodies b. Hybridoma technology is widely used for producing a.58.Plastcizer for the manicure preparation is(a)Caster oil plasticizer used (b)Cellulose nitrate (c)Butyl lactate (d)No . Callus cultures c.

Titanium di oxide used in the capsule coat as (a)Presrevatives (b)Plasticizer chewability (c)Opacifier (d)Inhance Q.Chitosan is a (a)Natural phospholipid (b) Natural polysachharide (c) Natural peptide hormone (d)Synthetic Q.66.69.Coating material which is water insoluble used in the microencapsulation(a)PVP (b)Polymethacrylate (c)CAP (d)PVA Q.If the drug is mois sensitive.material which leads to rigidity is(a)Cholesterol (b)Phosoholipid (c)PVP (d)PLGA Q.Which of the following are natural hydrocolloids- .65.Q.64.DMSO function as(a)An emulsifying agent (b)A suspending agent (c)A preservative (d)A penetration enhancer Q.binding agent utilize in this condition(a)CMC (b)Gelatin (c)HPMC (d)Starch paste Q.63.68.In the preparation of liposome.Matarial which is most commonly used for the enteric coating of tablets(a)PVP (b)CAP (c)Acrylates (d)Accacia Q.70.67.

(P)Hectorite (R)CMC (a)PQ (b) RS (Q)Attapulgite (S)Carbopols (c)PR (d)QS Q.74. Assertion (A): Sorbitol.The term----has been used to in the sense of increase in solubility in the water of various substances due to the presence of large amount of additives(a)Cosolvancy (b)Complexation (d)Solublization (c)Hydrotrophy Q.Which of the following is neutral preservatives(P)Benzyl alcohol (R)Phenol (a)PQ (b) RS (Q)Chlorbutanol (S)Nitromersol (c)PR (d)QS Q. Reason (R): They are reduces the interfacial tension (a)Both [A] and [R] are true and [R] is the correct reason for [A] (b)Both [A] and [R] are true but [R] is not the correct reason for [A] (c)Both [A] and [R] are false (d)[A] is true but [R] is false Q.Tween 60 is (a)Polyoxyethylene (20) sorbitone monolaurate (b)Polyoxyethylene (20) sorbitone monopalmitate (c)Polyoxyethylene (20) sorbitone monostearate (d) Polyoxyethylene (20) sorbitone monooleate . ethanol and glycerin act as cosolvent.73.72.71.

80.NDGA is (a)Antioxidant (b) Viscosity modifier (c) Vehicle (d) Filler Q.79.Accacia is used as(a)Suspending agent (d)All (b) Emulsifier (c) Microcapsule wall material Q.Controlled release excipient for tablet is (P)Mg.Binding/granulating agent who show the highest strength for the tablet formulatin (a)Acacia mucilage (b)Glucose syrup .78.Q.Silicates (R)PVP (a)PQ (b) RS (Q) Starch (S)HPMC (c)PR (d)QS Q.76.Al.77.75.Role of Dextrin is (P)Stabilizer (R)Binder (a)PQ (b) RS (Q) Emulsifier (S) Gelling agent (c)PR (d)QS Q.In the tablet formulation MCC is used as (a)Glidant (b) Antiadherent (c)Binder (d)All Q.

What is the HLB value for sodium lauryl sulphate? a) 10 b) 40 c) 25 d) 15 .What is the active ingredient present in mandle’s throat painta) Manganese b) Iodine c)Iron d) KI Q.82.FD&C color yellow 5 commonly known as (a)Erythrosine (c)Sunset Yellow (b)Indigotine (d)Tetrazine Q.Commanly used controlled release excipient which is pH dependent (a)CAP (b)PLGA (c)CMC (d)HPMC Q.87.86.Gelatin is a hydrolysed product of a) Shellac b) Pectin c) Collagen d) Tannin Q. Sorbitol used in soft gelatin capsules as a) Viscosity modifier b) Gel Strength modifier c) To alter the Cohesive strength d) Plasticizer Q.84.81.85.(c)Povidone (d)Sucrose syrup Q.83.Which of the following is incorporated to overcome crystallization or cap locking of simple syrup? a)Alcohol b)Glycerin c)Ether d) Purified water Q.

88.The following solvent is a water immiscible non aqueous solvent (a) Dioxalones (c) Isopropyl myristate (b) PEG 400 (d) Butylene glycol .89.90. Match the following HLB scale P) 3 – 8 Q) 3 – 1 R) 7 – 9 S) 16 – 18 T) 8 – 16 a) P – 2 Q–4 R–1 S–3 T–5 b) P – 5 Q–4 R–2 S–3 T-1 R–5 S–2 T–4 1) Anti foaming agent 2) W/O emulgent 3) Wetting agent 4) O/W emulgent 5) Solubilizing agent c) P – 3 d) P – 2 Q–1 R–3 S–5 T–4 Q–1 Q. Anhydrous lanolin is also called as a) Yellow soft paraffin c) Bees wax b) Wool fat d) Cholesterol Q.Q.Which of the following is used for the lubrication of moulds in the preparation cocoa butter suppositories by fusion method? a) Mineral oil c) Cetyl alcohol b) Propylene glycol d) Magnesium silicate Q.91.

P. Lecithin b.97.5 to 1 % methylene blue (b) methyl red (d)None Q. Propylene glycol a. Which of the following is an emollient used in the hand cream preparations a. P.94. R.95.Which of the following agents reduces the surface charges on the wet hair and to maintain the oily film present naturally on the hair a. Lanolin c. Dimethyl sulfoxide R. All the above Q.96. Propellent 152 a is(a) Trichloro di fluoro methane (b) difluoro ethane (c) trichloro mono fluoro Methane (d)Butane Q. Clarifying agents c. Glycerin S. Cholesterol d. Carbopol d.Q.93. Q b. The indicator used in leakage test for sterile products (a) crystal violet (c) 0. Which of the following substance enhances the penetration of drug in oral transmucosal drug delivery systems? P. S Q. During translation AUG codes for methionine at . Conditioning agents b. Chelating agents Q. Stabilizing agents d. S Q.92. R c. Q.

t – RNA Q. Vapour pressure d. The end of polypeptide chain c. The end well as the exterior of polypeptide chain Q.98. Vitamin B complex Q. Vitamin D b. Vitamin C c.Following Which statement is correct for auxochrome(a)All auxochrome have one or more non bonding pair of electrons (b)It is group which itself does not act as a chromophore (c)Extended conjugation has been responsible for bathochromic shift (d)All above statement are correct . m – RNA b.101. H2O solubility b. t.99.RNA d.100. The lethal effect of CO is due to a. The start of polypeptide chain b. Vitamin E d. Ability to combine with haemoglobin c.a. Anti codon region is an important part of the structure of a. The start as well as the interior of polypeptide chain d. DNA c.Which of the following vitamin has a deodrant property a. Ability to form CO2 easily Q.

106.K/µ (b)f= 1/2π K/µ (d) none (C ) f = 2π.104.107.Fundamental theory of IR absorption spectroscopy (a) f2 =I /4 π2.which type of transition are present in UV spectroscopy (a) π to π* (b) n to σ* (c) n to π* (d) all (e) a & c Q.103.102.unit of wave number is (a) Ao (b) CM-1 (c) Kayser (d) b and c Q.108.Which one is example of vacuum UV spectroscopy (a) CH3 CO CH3 (b) C6H5-NH2 . K/µ Q.in which radiation detection system of uV spectroscopy multiplication of primary photoelectrons (a)Barrier layer cells (b)photronic cells (c)photoemmisive cells (d) none Q.Q.photoemissive material used in u V detection to generate photo electron when visible/ UV light incident on detector (a)potassium (b) cesium (c) AgO (d) all Q.105.Fabry perot filter used in visible spectroscopy to achieved monochromatic light based on (a)Absorption (c)Interference (b)refraction (d) defraction Q.

Calculate the absorption maxiama for UV/ visible for following structure (a)398 nm (b) 360 nm (c) 362 nm (d) 353 nm Q.According to woodward fieser rure for polyenes basic value for λmax calculation to the following structure is (a) 215 nm (b) 317 nm (c) 245 nm (d)253 nm Q.111.Base peak is related to (a) Raman spectra (b) FTIR (c) MALDY TOF (d) Phosphorometry .113.2 to 2.5 to 15 µ (c) 25 to 300 µ (d) this motion not present in IR region Q.Calculate the absorption maxiama for UV/ visible for following structure (a)235 nm (b) 253 nm (c) 292 nm (d) 353 nm Q.Vibration motion in infra red taking place in which range (a) 1.115.Number of ring residue present in following structure (a) 5 (b) 4 (c) 3 (d) 2 Q.112.(c) Cyclohexane (d) B & C Q.5 µ (b) 1.114.Functional group detectin performed by (a) colorimetry (b) NMR Spectroscopy (c) IR Spectroscopy (d) 13C NMR Spectroscopy Q.110.109.

= Dipole-2 forces < Vander waal’s forces Q.Relative acidic character of following compounds (a) H2O >ROH> CHºCH> CH2=CH2 > CH3. (c) Vander waal’s forces > H. > Dipole-2 forces (d) H.CH3 > H2O (c) CHºCH > CH2 =CH2 >CH3.120.B.B.>Dipole-2 forces>Vander waal’s forces (b) Dipole-2 forces > Vander waal’s forces > H.Q.No bond resonance is also know as (a) mesomerism (b) Hyperconjugation (c) Baker and Nathan effect (d) b & c Q.117Hybridization of carbene ( ¯CH2 ) may be (a) SP2 (b) SP (c) SP3 (d) a & b Q. and tertiary monohydric alcohol is (a) ZnCl2 /conc HCl (b) anhydrous ZnCl/Conc HCl (c) Anhydrous ZnCl2 /Conc HCl (d) none Q.B.116.Correct relative order of forces present in covalent compound (a) H.Lucas reagent is used to differentiate the primary. secondary.B.CH3> H2O> ROH (d)CH3-CH3>CHºCH>CH2 =CH2 >CH3-CH3> H2O .118.109.CH3 (b) ROH > CHºCH >CH2 =CH2>CH3.

8 (c) 4. 16 (b) 2. 14. C6H5OH + CHCl3 + ? Þ Salicyaldehyde (a) Aqueous KOH (c) can be a & b (b) Alcoholic KOH (d) Li .Which of the following electronic displacement is responsible for Polarisability in the covalent compounds (a) Indutomeric effect (c) a & b (b) Electromeric effect (d) resonance effect Q. 6.123. 12. (d) 2. 12 Q.121.122. 8. 6.125. 6.Which of the following number of Pi electrons combination according to Huckel rule for aromaticity (a) 2.In which of the following electronic displacement is permanent in nature (a) Inductive effect (b) Hyperconjugative effect (c) mesomeric effect (d) all Q. 4.Q. 4.124. Stability order of the carbonium ions is (a) Cyclopropyl methyl carbocations>C6H5CH2+ > Allyl carbocations> Alkyl cabonium ions > Vinyl carbocations (b) C6H5CH2+ > Cyclopropyl methyl carbocations > Allyl carbocations> Alkyl cabonium ions > Vinyl carbocations (c)C6H5CH2+> Allyl carbocations > Alkyl cabonium ions>Vinyl carbocations>Cyclopropyl methyl carbocations (d) C6H5CH2+ > Allyl carbocations> Cyclopropyl methyl carbocations > Alkyl cabonium ions > Vinyl carbocations Q. 10.

Q.Wavelength range of X.130.128.127.126.129.131. Crystal structure of water floats in the water due to low density of crystal structure exits in form of (a) Tetramer form (c) Hexamer form (b) Pentamer form (d) None Q. Most intense peak in mass spectroscopy is (a) parent peak (b) base peak (c) both have similar intense peak (d) metastable peak Q. correct order of hydrogen bonding (a) HF::::HF > OH::::::: OH > HF::::HF > NH::::::NH OH::::::: OH HF::::HF (b) NH::::::NH > (c) OH::::::: OH > NH::::::NH > (d) HF::::HF = OH::::::: OH > NH::::::NH Q.Woodward fieser rules for alkenes is valid up to number of conjugated double bonds is (a) 5 (b) 6 (c) 4 (d) no any criteria like this Q.100A0(d)1-10 CM-1 Q.Rays is (a) 1-100 A0 (b) 1-10 A0(c)10. Stability order of carbanions is (a) 10 > 20 > 30 (b) 10 = 20 > 30 .

charged electrophiles are (a) H+ (b) NH4+ (c) NO2+ (d) all Q.135.134. Neutral electrophile is (a) PCl5 (b) SF6 (c) NO2+ (d) all (e) a&b Q.133.136.132.In colorimetry transition take place from to (a)Ground to exited (b)Boding orbiatal to antibonding orbital (c) LUMO to HOMO (d) all .(c) 20 > 30 > 10 (d) 30 > 20 > 10 Q.138. Forbidden transition in uv spectroscopy is due to (a) π to π* (b) n to σ* (c) n to π* (d) b & c Q.Homolytic cleavage of organic compounds is responsible for (a)Odd electron species (b) nucleophiles generation (c)free radicals generation(d)electrophiles generation Q.137. Mull technique is a method of sampling belong to(a) Mass spectroscopy (b) IR(c) NMR (d) X – Rays Q. Carbylamine is a characteristics reaction in the presence of CHCl3 & Alcoholic KOH to produce isocyanide (a) secondary amine (c) phenol (b) primary amine (d) ether Q.

Q. A colorimetry sample solution color is blue which color of filter should be suitable for filter (a) Orange (b) Blue (c) Red (d) any color which is transparent to visible range Q.139.145 Warty out growth from micropyle is known as caruncle found in (a) cardamom (b) Calotropis .141 Choose the odd one (a) Gibberlline (b) Auxin (c) Ethylene (d) Zeatin Q.143 Java cinnamon has ----------------.142 Glycerrhiza is modified (a) Runner (b) Stolen (c) Offset (d) Sucker Q.bark (a) Recurved (c) Compound Quill (b) Quill shaped (d) None Q.Grating use as monochromator in IR spectrum is made of (a) Glass (b) Quartz (c) fused silica (d) NaCl Q.140.144 Choose the odd one with respect to modification to fruit (a) Strawberry (c) Rose (b) marking fruit (d) Apple Q.

(c) Colchicum (d) Castor Q.146 Inulin is polysaccharide.149 Osazone formation test is used to identify (a) Protein (c) Glycoside (b) Steroid (d) None Q. when administered to a living organism. and latex are----------------.150 Renin is a (a)Proteolytic enzyme (b) Mucolytic enzyme (c) Amylolytic enzyme (d) None Q.in water (a) soluble (c) Partially soluble (b) Insoluble (d) none Q. (b) a chemical substance of known structure. .147 Tannin. which. produces a biological effect. when administered to a living organism. which.product (a) Reserve (c) Excretory (b) secretory (d) metabolite Q. mainly a nutrient or an essential dietary ingredient.1 what is the drug (a) a chemical substance of known structure.148 Picrolonic acid is used to identify (a) Terpenoid (b) Alkaloid (c) Steroid (d) All Q. resin. produces a new biological function . it is ------------. other than a nutrient or an essential dietary ingredient.

Produce their response: Region-Due to efficacy (a) Assertion is wrong& region is true (b) Assertion is true & region is wrong (c) both wrong Q. (b)The higher the affinity of the drug for the receptor. (d) a chemical substance of known structure. the lower the concentration at which it produces a given level of occupancy. mainly a nutrient or an essential dietary ingredient.4 Target proteins on which drug act is (a) Receptor (b) enzymes (c) carriers (d) all Q. which.(c) a chemical substance of known structure. when administered to a living organism. Correct for Binding of drugs to receptors (a)Binding of drugs to receptors necessarily obeys the Law of Mass Action. Q. . when administered to a living organism. which. produces a biological effect.3 Spare receptor is (a) Fallow occupation concept (b) Not fallow occupation concept (c) Not fallow two step model (d) none (d) both true Q. other than a nutrient or an essential dietary ingredient.5 Hill-Langmuir equation described the (a) Quantitative aspects of drug-receptor interactions (b) Qualitative aspects of drug-receptor interactions (c) Quantitative aspects of drug-drug interactions (d) Qualitative aspects of drug-drug interactions Q. produces a new biological function.2 Drug bind to receptor.6. Assertion .

8.Poison is pertussis and cholera toxin Region.10. Tetrodotoxin is(a) Voltage-gated sodium channels modulator (b) Voltage-gated sodium channels blocker (c) Voltage-gated sodium channels agonist (d) Voltage-gated sodium channels antagonist Q.7.and DNA-binding domains Q.11 Intra Cellular Release of Ca++ ion increased by the (a) PLC (b) DAG (c) IP3 (d) IP4 .9 Type 3 receptor structures is (a) Oligomeric assembly of subunits surrounding central pore (b) Monomeric dimericor structure comprising seven transmembrane helices (c) Single transmembrane helix linking extracellular receptor domain to intracellular kinase domain (d) Monomeric structure with separate receptor.(c)The same principles apply when two or more drugs compete for the same receptors. (d) all Q. A person suffer from excessive lipolysis when he take mistakenly a poison Assertion. each has the effect of reducing the apparent affinity for the other.Prevent inactivation of GPCRs (a) Assertion is wrong & region is true (b) Assertion is true & region is wrong (c) Both wrong (d) both true Q. choose the correct statement for the GPCRs (a) Membrane location (b) Effectors is only ion channel (c) Effectors is only enzyme (d) all Q.

The semilogarithmic plot of plasma concentration (Cp) versus time appears to indicate that the drug is eliminated from a single compartment by a first-order process with k = 0.4 then rate of reabsorption of drug from renal tuble is(a) High (b) low (c) may be high or low (d) not predict Q.19 Drug concentrations are measured in plasma at 2-hour intervals following drug administration. when clearance is constant .Q. what is the role of IP4 Formed from IP3 during PI cycle(a) Absolutely faccillate Ca++ ion entry via plasma membrane (b) unclear but may faccillate Ca++ ion entry via plasma membrane (c) Activate PKa (d) Inactivate Pka Q.16 N-acetyl-p-benzoquinone imine is (a) non toxic metabolite of acetaminophen ( b) toxic prodrug of acetaminophen (c) toxic metabolite of acetaminophen (d) none Q. (a) indirectly (b) directly (c) not depend (d) none Q. the rate of drug elimination is -----------------proportional to drug concentration.15 Presystemic Metabolism also known as (a) First pass metabolism (c) phase 2 (b) phase 1 (d)none Q. A drug which pka is 3.18.17 What is the unit of Michalies menten constant (a) no unit (b) amount unit (c) concentration unit (d) a&b Q.13 Secondary messengers is except (a) cGMP (b) cAMP (c) IP3 (d) PLC Q.14.12.173 hr–1) then half life of drug is .

22 All of the following are capable of initiating a signal transduction process EXCEPT (A) Combination of an agonist with its receptor (B) Combination of an antagonist with its receptor (C) Combination of a neurotransmitter with its receptor (D) Combination of a hormone with its receptor Q. a drug is absorbed into the body. (a) agonist (c) Inverse agonist (b) partial agonist (d) antagonist Q.23.(a) 240 min (b) 180 min (c) 120 min (d) 60 min Q. For a drug given orally. Following oral administration. that enter the body.21 Phase 2 clinical trials investigate the (a) safety (b) efficacy (c) verify efficacy (d) Obtain additional data following approval Q.24.25. wherein it can exert its action. such as drugs.20 Here B is. the primary site of drug absorption is: (A) The esophagus (B) The stomach (C) The upper portion of the small intestine (D) The large intestine Q. One of the more prominent of these mechanisms is an efflux transport system that pumps some drugs back into .The body has developed defense mechanisms that reduce the amount of foreign chemicals. Potency is determined by (A) Affinity alone (B) Efficacy alone (C) Affinity and efficacy (D) Efficacy and intrinsic activity Q.

Receptor (d) all Q.Receptor (c) Chemokine – Receptor (b) PGS .31 All are GPCRS EXCEPT(a) 5-HT3.32.28.Receptor (b) D2.27.Receptor Q. Which of the following pharmacokinetic parameters defines the exposure of a person to a drug? (A) Cmax (B) Tmax (C) AUC (D) Half-life Q.29.the intestinal lumen following absorption into the enterocytes and that is responsible for the lack of complete absorption of some drugs.Receptor (c) GABAB . Which of the following CYP enzymes is associated with metabolism of the greatest number of drugs and thus most likely to be involved in drug–drug interactions? (A) CYP3A4 (B) CYP2C9 (C) CYP2D6 (D) CYP2E1 Q.34 Blood Glycogen rises when- . Frequently it is useful to consider the overall exposure of a person to a drug during the dosing interval.This efflux transport system is: (A) Facilitated diffusion (B) P glycoprotein (C) Cytochrome P450 3A (D) Pinocytosis Q. cAMP pathway starts with the(a)Activation of adenyl cyclase (b) Activation of protein kinase (c) Exchange of GDP with GTP in α – Units of G-protein (d) Exchange of ATP with ADP in α – Units of G-protein Q. Reaction is(A) Phase 1 (B) Phase 2 (C) Phase 3 (D) Phase 4 Q.Receptor (d) Opiod.30 Agonist pleotropy shown by the(a) M.

38 Intrinsic activity for DMCM is(a) 0----(-1) (b) 0-----(+1) (c) 0 (d) 1 Q.Transducer steps ----response--.Transducer steps ----response (b) Binding to receptor----.40 Albumin is the (a) Silent receptor C (b) nuclear receptor (c) Protien channel (d) A& Q.39 Correct sequence by which the drug work(a) Binding to receptor----.confermation change ----response---.Transducer steps (c) Binding to receptor----.41 Choose incorrect statement when drug is given by oral route (a) Slower action not suitable for emergency (b) Streptomycin is not absorbed by oral route (c) Cannot used for uncooperative patient (d) None .35 Drug which produce opposite effect to agonist is called(a) Antagonist (c) Invese agonist (b) Partial agonist (d) Blocker Q.Transducer steps ----response Q.36 Iproniazid is the(a) Antitubercular drug (c) Anticancer drug (b) MOA-A inhibitors (d) Antileprotic drug Q.confermation change---.chemical change---.(a) cAMP increases (b) cAMP Decreases (c) IP3/ DAG increase (d) A&C Q.37 Occupation of receptor is governed by the(a) Affinity (b) Intrinsic activity (c) Confermation chages (d) all Q.confermation change (d) Binding to receptor----.

but by mistak patient take enzyme inducer with them. the urine was found alkaline.46 A doctor have prescribed paracetamol to the patient . Cispride (b) CYP2D6.43 Find the volume of distribution of drug if plasma concentration of drug is 50 Mg/L and the totel drug in body is 100Mg (a) 2L (b) 20ML (c) 2000ML (d) 50ML Q.Astemizole (d) CYP2C8/9 .44 Which of the following enzyme responsible for the conversion of the codeine to morphine and this is inhibited by (a) CYP2E1. which is responsible for the (a) Inhibition of CYP1A isoenzyme (b) Inhibition of CYP3A isoenzyme (c) Induction of CYP1A isoenzyme (d) Induction of CYP2B1 isoenzyme Q. Diltiazim Q.Q.47 Probenacid prolong the duration of action of penicillin and ampicilline by (a) By reducing rate of metabolism binding (b) By increasing plasma protein (c) By prolonging absorption from absorption site (d) By reducing rate of excretion Q. in this condition which drug is back diffuse in the kidney tubules (a) Aspirin (b) Ciprofioxacin (c) both (d) none Q. Quinidine (c) CYP2C19 .48 Which of the following is example of non competitive inhibitors . what would happened (a) Increase intensity of response (b) Increase duration of action (c) Toxicity (d) both a & b Q.42 A patient take combination of aspirin and ciprofloxacin.45 Benzopyren found in cigratte smoke . during the testing of urine.

(a) Physostigmine (c) Theophylline (b) Allopurinol (d) Carbidopa Q.Flavouring agent. who is used in the formulation of oral liquids.52.51.Vmax increase Q.49 Choose correct one for the non equilibrium type enzyme inhibition (a) Km increase .unionized form is present in the stomach but ionized in the intestine (d)All Q. gives the bitter test(P)Wild Cherry(Q)Liquorice (R)Mint(S)Vanilla (a)PQ (b) RS (c)PR (d)QS (b) Aspirin & paracetmol (d) Nitrous acid & Ether Q. Vmax constant (d) Km decrease .Ascorbic acid is an antioxidant functioning (P)Reducing agent (S)Chelates (a)PQ (b) RS (Q)Oxidising agent (c)PR (d)QS (R)Synergistic .50Choose correct example for supra additive combination (a) Acetylcholine & Physostigmine (c) Ephedrine & Theophylline Q.53. Vmax decrease (c) Km decrease .Which of the following statement is true(a)Determination of pKa performed by spectral shift or visible spectroscopy (b)Unionized form is greatly absorbed than the ionized form (c)Drug with low pKa value.Vmax decreases (b) Km constant .

Most commonly used non aquous vehicle for sterile product is (a)Corn oil oil (b)Almond oil (c)Peanut oil (d)Sesame Q.Sterile water for injection is(a)Not contain any antmicrobial agent free (c)Filled in single dose container true (b)Must be pyrogen (d)All statement are Q.55.56.58.57. Callus cultures c. All the above . Hybridoma technology is widely used for producing a.Which statement is false about the ASPARTAME (a)200 times more sweet than sucrose (b)No bitter after test (c)High water solubility and stable at wide pH range (d)Not recomonded for the pregnant or lacting woman Q.54.Function of tonocity modifier for the parenterals(a)Minimize tissue damaze and ↓ irritation cells (c)Prevent electrolyte imbalance (d)All (b)↓hemolysis of blood Q. Organ cultures d.Q. Monoclonal antibodies b.

In the preparation of liposome.Q.64.61.Matarial which is most commonly used for the enteric coating of tablets(a)PVP (b)CAP (c)Acrylates (d)Accacia .63.59.material which leads to rigidity is(a)Cholesterol (b)Phosoholipid (c)PVP (d)PLGA Q.For the preparation of W/O/W type multiple emulsion.Which of the following statement is true about the MC(a)Soluble in hot water but insoluble in cold water (b)Soluble in cold water but insoluble in hot water (c)Insoluble in all conditions (d)Highly soluble in organic solvents Q.the correct scheme of the addition of emulsifiers(a)Span→tween (b)Tween→span (c)Both (d) None Q.60.Polyoxyethylene sorbiton is the example of a surfactant which is(a)Non ionic (c)Anionic (b)Cationic (d)Amholytic Q.62.Plastcizer for the manicure preparation is(a)Caster oil plasticizer used (b)Cellulose nitrate (c)Butyl lactate (d)No Q.

68.69.Chitosan is a (a)Natural phospholipid (b) Natural polysachharide (c) Natural peptide hormone (d)Synthetic Q.binding agent utilize in this condition(a)CMC (b)Gelatin (c)HPMC (d)Starch paste Q.If the drug is mois sensitive.65.DMSO function as(a)An emulsifying agent (b)A suspending agent (c)A preservative (d)A penetration enhancer Q. .71.67.66.Titanium di oxide used in the capsule coat as (a)Presrevatives (b)Plasticizer chewability (c)Opacifier (d)Inhance Q. ethanol and glycerin act as cosolvent.Q. Assertion (A): Sorbitol.70.Coating material which is water insoluble used in the microencapsulation(a)PVP (b)Polymethacrylate (c)CAP (d)PVA Q.Which of the following are natural hydrocolloids(P)Hectorite (R)CMC (a)PQ (b) RS (Q)Attapulgite (S)Carbopols (c)PR (d)QS Q.

Reason (R): They are reduces the interfacial tension (a)Both [A] and [R] are true and [R] is the correct reason for [A] (b)Both [A] and [R] are true but [R] is not the correct reason for [A] (c)Both [A] and [R] are false (d)[A] is true but [R] is false Q.The term----has been used to in the sense of increase in solubility in the water of various substances due to the presence of large amount of additives(a)Cosolvancy (b)Complexation (d)Solublization (c)Hydrotrophy Q.76.75.73.Tween 60 is (a)Polyoxyethylene (20) sorbitone monolaurate (b)Polyoxyethylene (20) sorbitone monopalmitate (c)Polyoxyethylene (20) sorbitone monostearate (d) Polyoxyethylene (20) sorbitone monooleate Q.Accacia is used as(a)Suspending agent (d)All (b) Emulsifier (c) Microcapsule wall material Q.74.Role of Dextrin is (P)Stabilizer (Q) Emulsifier .72.Which of the following is neutral preservatives(P)Benzyl alcohol (R)Phenol (a)PQ (b) RS (Q)Chlorbutanol (S)Nitromersol (c)PR (d)QS Q.

In the tablet formulation MCC is used as (a)Glidant (b) Antiadherent (c)Binder (d)All Q.(R)Binder (a)PQ (b) RS (S) Gelling agent (c)PR (d)QS Q.NDGA is (a)Antioxidant (b) Viscosity modifier (c) Vehicle (d) Filler Q.Binding/granulating agent who show the highest strength for the tablet formulatin (a)Acacia mucilage (c)Povidone (b)Glucose syrup (d)Sucrose syrup Q.Al.80.FD&C color yellow 5 commonly known as (a)Erythrosine (c)Sunset Yellow (b)Indigotine (d)Tetrazine .79.Silicates (R)PVP (a)PQ (b) RS (Q) Starch (S)HPMC (c)PR (d)QS Q.Controlled release excipient for tablet is (P)Mg.77.78.81.

86. Match the following HLB scale P) 3 – 8 Q) 3 – 1 R) 7 – 9 S) 16 – 18 T) 8 – 16 1) Anti foaming agent 2) W/O emulgent 3) Wetting agent 4) O/W emulgent 5) Solubilizing agent .83.Gelatin is a hydrolysed product of a) Shellac b) Pectin c) Collagen d) Tannin Q.87. Sorbitol used in soft gelatin capsules as a) Viscosity modifier b) Gel Strength modifier c) To alter the Cohesive strength d) Plasticizer Q.What is the active ingredient present in mandle’s throat painta) Manganese b) Iodine c)Iron d) KI Q.85.88.Which of the following is incorporated to overcome crystallization or cap locking of simple syrup? a)Alcohol b)Glycerin c)Ether d) Purified water Q.82.84.Commanly used controlled release excipient which is pH dependent (a)CAP (b)PLGA (c)CMC (d)HPMC Q.What is the HLB value for sodium lauryl sulphate? a) 10 b) 40 c) 25 d) 15 Q.Q.

5 to 1 % methylene blue (b) methyl red (d)None Q.92. The indicator used in leakage test for sterile products (a) crystal violet (c) 0.Which of the following is used for the lubrication of moulds in the preparation cocoa butter suppositories by fusion method? a) Mineral oil c) Cetyl alcohol b) Propylene glycol d) Magnesium silicate Q.91. Anhydrous lanolin is also called as a) Yellow soft paraffin c) Bees wax b) Wool fat d) Cholesterol Q.93.90.a) P – 2 Q–4 R–1 S–3 T–5 b) P – 5 Q–4 R–2 S–3 T-1 c) P – 3 d) P – 2 Q–1 Q–1 R–3 S–5 T–4 R–5 S–2 T–4 Q.89.The following solvent is a water immiscible non aqueous solvent (a) Dioxalones (c) Isopropyl myristate (b) PEG 400 (d) Butylene glycol Q. Propellent 152 a is- .

Conditioning agents b. S Q.94. Which of the following substance enhances the penetration of drug in oral transmucosal drug delivery systems? P. All the above Q. Glycerin S. Propylene glycol a. R. The start as well as the interior of polypeptide chain d. Q.Which of the following vitamin has a deodrant property . The end well as the exterior of polypeptide chain Q. Which of the following is an emollient used in the hand cream preparations a. Q b. The end of polypeptide chain c. R c.96. Carbopol d. Cholesterol d. The start of polypeptide chain b.95.Which of the following agents reduces the surface charges on the wet hair and to maintain the oily film present naturally on the hair a.97. Lecithin b. Lanolin c. P. Chelating agents Q. P. During translation AUG codes for methionine at a. Dimethyl sulfoxide R.98. Clarifying agents c. Stabilizing agents d. S Q.(a) Trichloro di fluoro methane (b) difluoro ethane (c) trichloro mono fluoro Methane (d)Butane Q.

K/µ (b)f= 1/2π K/µ (d) none (C ) f = 2π. H2O solubility b.100.99. m – RNA b. Vitamin E d.102. Ability to combine with haemoglobin c. Vitamin B complex Q.101. Vitamin D b.Fabry perot filter used in visible spectroscopy to achieved monochromatic light based on (a)Absorption (c)Interference (b)refraction (d) defraction . Vapour pressure d.RNA d. DNA c. Anti codon region is an important part of the structure of a.Fundamental theory of IR absorption spectroscopy (a) f2 =I /4 π2.103. t – RNA Q.Following Which statement is correct for auxochrome(a)All auxochrome have one or more non bonding pair of electrons (b)It is group which itself does not act as a chromophore (c)Extended conjugation has been responsible for bathochromic shift (d)All above statement are correct Q. The lethal effect of CO is due to a.a. Ability to form CO2 easily Q. K/µ Q. Vitamin C c. t.

106.108.105.photoemissive material used in u V detection to generate photo electron when visible/ UV light incident on detector (a)potassium (b) cesium (c) AgO (d) all Q.107.unit of wave number is (a) Ao (b) CM-1 (c) Kayser (d) b and c Q.Calculate the absorption maxiama for UV/ visible for following structure (a)398 nm (b) 360 nm (c) 362 nm (d) 353 nm Q.in which radiation detection system of uV spectroscopy multiplication of primary photoelectrons (a)Barrier layer cells (b)photronic cells (c)photoemmisive cells (d) none Q.109.which type of transition are present in UV spectroscopy (a) π to π* (b) n to σ* (c) n to π* (d) all (e) a & c Q.Calculate the absorption maxiama for UV/ visible for following structure .110.Which one is example of vacuum UV spectroscopy (a) CH3 CO CH3 (b) C6H5-NH2 (c) Cyclohexane (d) B & C Q.104.Q.

Vibration motion in infra red taking place in which range (a) 1.116.115.Number of ring residue present in following structure (a) 5 (b) 4 (c) 3 (d) 2 Q.113.According to woodward fieser rure for polyenes basic value for λmax calculation to the following structure is (a) 215 nm (b) 317 nm (c) 245 nm (d)253 nm Q.2 to 2.114.117Hybridization of carbene ( ¯CH2 ) may be .112.Functional group detectin performed by (a) colorimetry (b) NMR Spectroscopy (c) IR Spectroscopy (d) 13C NMR Spectroscopy Q.(a)235 nm (b) 253 nm (c) 292 nm (d) 353 nm Q.Lucas reagent is used to differentiate the primary.111.Base peak is related to (a) Raman spectra (b) FTIR (c) MALDY TOF (d) Phosphorometry Q. secondary.5 to 15 µ (c) 25 to 300 µ (d) this motion not present in IR region Q.5 µ (b) 1. and tertiary monohydric alcohol is (a) ZnCl2 /conc HCl (b) anhydrous ZnCl/Conc HCl (c) Anhydrous ZnCl2 /Conc HCl (d) none Q.

CH3> H2O> ROH (d)CH3-CH3>CHºCH>CH2 =CH2 >CH3-CH3> H2O Q.B.>Dipole-2 forces>Vander waal’s forces (b) Dipole-2 forces > Vander waal’s forces > H.CH3 (b) ROH > CHºCH >CH2 =CH2>CH3.121.122.B.Correct relative order of forces present in covalent compound (a) H.B. > Dipole-2 forces (d) H. = Dipole-2 forces < Vander waal’s forces Q.B.Which of the following electronic displacement is responsible for Polarisability in the covalent compounds .120. (c) Vander waal’s forces > H.118.No bond resonance is also know as (a) mesomerism (b) Hyperconjugation (c) Baker and Nathan effect (d) b & c Q.109.In which of the following electronic displacement is permanent in nature (a) Inductive effect (b) Hyperconjugative effect (c) mesomeric effect (d) all Q.Relative acidic character of following compounds (a) H2O >ROH> CHºCH> CH2=CH2 > CH3.(a) SP2 (b) SP (c) SP3 (d) a & b Q.CH3 > H2O (c) CHºCH > CH2 =CH2 >CH3.

127. 6.Rays is (a) 1-100 A0 (b) 1-10 A0(c)10. 8 (c) 4. Stability order of the carbonium ions is (a) Cyclopropyl methyl carbocations>C6H5CH2+ > Allyl carbocations> Alkyl cabonium ions > Vinyl carbocations (b) C6H5CH2+ > Cyclopropyl methyl carbocations > Allyl carbocations> Alkyl cabonium ions > Vinyl carbocations (c)C6H5CH2+> Allyl carbocations > Alkyl cabonium ions>Vinyl carbocations>Cyclopropyl methyl carbocations (d) C6H5CH2+ > Allyl carbocations> Cyclopropyl methyl carbocations > Alkyl cabonium ions > Vinyl carbocations Q. 10. 14.125. 6. 8. 12. 16 (b) 2. 4.Wavelength range of X. 4.126.100A0(d)1-10 CM-1 . 6. Most intense peak in mass spectroscopy is (a) parent peak (b) base peak (c) both have similar intense peak (d) metastable peak Q.(a) Indutomeric effect (c) a & b (b) Electromeric effect (d) resonance effect Q. C6H5OH + CHCl3 + ? Þ Salicyaldehyde (a) Aqueous KOH (c) can be a & b (b) Alcoholic KOH (d) Li Q. 12 Q.Which of the following number of Pi electrons combination according to Huckel rule for aromaticity (a) 2.124. (d) 2.123.

Woodward fieser rules for alkenes is valid up to number of conjugated double bonds is (a) 5 (b) 6 (c) 4 (d) no any criteria like this Q.128.134. correct order of hydrogen bonding (a) HF::::HF > OH::::::: OH > HF::::HF > NH::::::NH OH::::::: OH HF::::HF (b) NH::::::NH > (c) OH::::::: OH > NH::::::NH > (d) HF::::HF = OH::::::: OH > NH::::::NH Q.129. Neutral electrophile is (a) PCl5 (b) SF6 (c) NO2+ (d) all (e) a&b Q. Mull technique is a method of sampling belong to(a) Mass spectroscopy (b) IR(c) NMR (d) X – Rays Q. Crystal structure of water floats in the water due to low density of crystal structure exits in form of (a) Tetramer form (c) Hexamer form (b) Pentamer form (d) None Q.131.133.132.Q. Stability order of carbanions is (a) 10 > 20 > 30 (b) 10 = 20 > 30 (c) 20 > 30 > 10 (d) 30 > 20 > 10 Q.130. Carbylamine is a characteristics reaction in the presence of CHCl3 & Alcoholic KOH to produce isocyanide .

136.In colorimetry transition take place from to (a)Ground to exited (b)Boding orbiatal to antibonding orbital (c) LUMO to HOMO (d) all Q.140.Grating use as monochromator in IR spectrum is made of (a) Glass (b) Quartz (c) fused silica (d) NaCl .138.139.137.Homolytic cleavage of organic compounds is responsible for (a)Odd electron species (b) nucleophiles generation (c)free radicals generation(d)electrophiles generation Q. charged electrophiles are (a) H+ (b) NH4+ (c) NO2+ (d) all Q. A colorimetry sample solution color is blue which color of filter should be suitable for filter (a) Orange (b) Blue (c) Red (d) any color which is transparent to visible range Q.135.(a) secondary amine (c) phenol (b) primary amine (d) ether Q. Forbidden transition in uv spectroscopy is due to (a) π to π* (b) n to σ* (c) n to π* (d) b & c Q.

146 Inulin is polysaccharide.product .bark (a) Recurved (c) Compound Quill (b) Quill shaped (d) None Q. resin.142 Glycerrhiza is modified (a) Runner (b) Stolen (c) Offset (d) Sucker Q.144 Choose the odd one with respect to modification to fruit (a) Strawberry (c) Rose (b) marking fruit (d) Apple Q.145 Warty out growth from micropyle is known as caruncle found in (a) cardamom (c) Colchicum (b) Calotropis (d) Castor Q. it is ------------.141 Choose the odd one (a) Gibberlline (b) Auxin (c) Ethylene (d) Zeatin Q. and latex are----------------.in water (a) soluble (c) Partially soluble (b) Insoluble (d) none Q.Q.147 Tannin.143 Java cinnamon has ----------------.

150 Renin is a (a)Proteolytic enzyme (b) Mucolytic enzyme (c) Amylolytic enzyme (d) None Contact 09907862 .149 Osazone formation test is used to identify (a) Protein (c) Glycoside (b) Steroid (d) None Q.148 Picrolonic acid is used to identify (a) Terpenoid (b) Alkaloid (c) Steroid (d) All Q.(a) Reserve (c) Excretory (b) secretory (d) metabolite Q.