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Generic Name/ Brand Name

Date Ordered/ Date Performed/ Date change or DC January 31, 2012

Route of Administrati on, dosage, frequency

General Action, Classification, Mechanism of action

Contraindications Indication/ Purpose

Side Effects, Adverse Effects

Nursing Considerations

Gentamicin

15 mg IV now then OD

Contraindicated with patients who Aminoglycoside Serious has an allergy on aminoglycoside. infections Mechanism of Use cautiously with caused by action: renal or hepatic susceptible disease; hearing strains of Bactericidal, loss; active Pseudomonas inhibits protein infection with aeruginosa, synthesis in herpes; vaccinia, susceptible proteus species, varicella, fungal strains of graminfections, Escherichia coli, negative bacteria; mycobacterial Klebsiella appears to disrupt infections, Enterobacter functional integrity pregnancy. Serratia of bacterial cell species, membrane, Citrobacter, causing cell death. Staphylococcus species. Serious infections when causative organisms are Classification: Parenteral:

Side effects: diarrhea


Adverse effects: CNS: Ototoxicity tinnitus, dizziness, vertigo, deafness (partially reversible to irreversible), vestibular paralysis, confusion, disorientation, depression, lethargy, nystagmus, visual disturbances, headache, numbness, tingling, tremor, paresthesias, muscle twitching, seizures, muscular weakness, neuromuscular blockade C V:Palpitations, hypotension,

Determine previous hypersensitivity reactions to penicillins, cephalosporins, and other allergens prior to therapy. Lab tests: Baseline C&S tests prior to initiation of therapy, start drug pending results; periodic assessments of renal, hepatic, and hematologic functions should be made during prolonged therapy. Monitor for S&S of an urticarial rash (usually occurring within a few days after start of drug) suggestive of a hypersensitivity

not known.

hypertension GI: Hepatic toxicity, nausea, vomiting, anorexia, weight loss, stomatitis, increased salivation GU: Nephrotoxicity Hematologic: Leukemoid reaction, agranulocytosis, granulocytosis, leukopenia, leukocytosis, thrombocytopenia, eosinophilia, pancytopenia, anemia, hemolytic anemia, increased or decreased reticulocyte count, electrolyte disturbances Hypersensitivity: Purpura, rash, urticaria, exfoliative dermatitis, itching Local: Pain, irritation, arachnoiditis at IM injection sites Other: Fever, apnea, splenomegaly, joint pain,superinfections Ophthalmic preparations

reaction. If it occurs, look for other signs of hypersensitivity (fever, wheezing, generalized itching, dyspnea), and report to physician immediately. Report onset of generalized, erythematous, maculopapular rash (ampicillin rash) to physician. Ampicillin rash is not due to hypersensitivity; however, hypersensitivity should be ruled out. Closely monitor diarrhea to rule out pseudomembranous colitis

Local: Transient irritation, burning, stinging, itching, angioneurotic edema, urticaria, vesicular and maculopapular dermatitis Topical dermatologic preparations Local:Photosensit ization,superinfection s

Generic Name/ Brand Name

Date Ordered/ Date Performed/ Date change or DC January 30, 2012

Route of Administrati on, dosage, frequency

General Action, Classification, Mechanism of action

Contraindications Indication/ Purpose

Side Effects, Adverse Effects

Nursing Considerations

Ampicillin

Classification: Penicillin Mechanism of

Used for treating Contraindicated with patients who bacterial has an allergy on infection penicillins.

Side effects: Diarrhea

Tell patient that medication may cause nausea or vomiting(small, frequent meals,

action: Ampicillin belongs to a class of antibiotics called penicillins that are used for treating bacterial infections. They stop bacteria from multiplying by preventing bacteria from forming the walls that surround them. The walls are necessary to protect bacteria from their environment and to keep the contents of the bacterial cell together. Bacteria cannot survive without a cell wall. Penicillins are most effective when bacteria are actively multiplying and forming cell walls. Ampicillin is Adverse effects: Gl- Glossitis, stomatitis, black "hairy" tongue, nausea, vomiting, enterocolitis, pseudomembrano us colitis, and diarrhea. (These reactions are usually associated with oral dosage forms.) Hypersensitivity reaction- Skin rashes and urticarial, Anaphylaxis Liver- moderate rise in serum glutamic oxaloacetic transaminase (SGOT) Hemic and Lymphatic Systems- Anemia,

frequent mouth care, sucking lozenges, or chewing gum may help); or diarrhea (buttermilk, boiled milk, or yogurt may help). Instruct client to maintain adequate hydration (2-3 L/day of fluids) unless instructed to restrict fluid intake

effective against many bacteria including H. influenzae, N. gonorrhoea, E. coli, Salmonella, and Shigella, streptococci and certain strains of staphylococci.

thrombocytopenia, thrombocytopenic purpura, eosinophilia, leukopenia, and agranulocytosis:

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