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Adrianne Bazo October 21, 2008 NURS 2516 Clinical Medications Worksheets Generic Name pantoprazole Peak Unknown Trade

Name Protonix IV Classification antiulcer agents, gastric acid pump inhibitors Dose Route Time/frequency: 40 mg IV Q 24hrs Dose Range: Rate of Administration (IV) 40mg q day for Administer 4 mg/ml solution 7-10 days undiluted over at least 2 min. Duration For IV meds 1 week Compatibility with IV drips and /or solutions:
Administer the 4 mg/mL solution undiluted Rate: Administer over at least 2 min

Onset 2.5 hrs

Mechanism of action and indications (Why med ordered) Binds to an enzyme in the presence of acidic gastric pH, preventing the final transport of hydrogen ions into the gastric lumen Diminished accumulation of acid in the gastric lumen, with lessened acid reflux, Healing of duodenal ulcers and esophagitis, Decreased acid secretion in hypersecretory conditions. Heartburn Interactions with other patient drugs, OTC or herbal medicines (ask patient specifically) None known

Y-Site incompatibility: administer through a dedicated line or flush line before and after. Do not administer in line with other solutions. Midazolam, solutions containing zinc Nursing Implications (what to focus on) Contraindications/warnings/interactions
Hypersensitivity, may alter the bioavailability and effects of drugs for which absorption is pHdependent. Reconstitute each vial with 10ml of 0.9% NaCl for a concentration of 4 mg/ml (solution is stable for 6 hr at room temp). Patients receiving pantoprazole IV should be converted to PO dosing as soon as possible

Common side effects No common side effects Lab value alterations caused by medicine May cause abnormal liver function tests, including ↑ AST, ALT, alkaline phosphatase, and bilirubin Be sure to teach the patient the following about this medication Instruct patient to take medication as directed for the full course of therapy, even if feeling better, take before meals. Advise patient to avoid alcohol, products containing aspirin or NSAIDs, and foods that may cause an increase in GI irritation, Advise patient to report onset of black, tarry stools; diarrhea; or abdominal pain to health care professional promptly Evaluation Check after giving Healing in patients with erosive esophagitis. Therapy is continued for up to 8 wk

Nursing Process- Assessment (Pre-administration assessment) Assess patient routinely for epigastric or abdominal pain and for frank or occult blood emesis, or gastric aspirate.

Assessment Why would you hold or not give this med? Hypersensitivity, signs of gastric bleeding