San Jos State University Biological Sciences Bio 107, Immunology, Spring 2012 Instructor: Office Location: Telephone:

Email: Office Hours: Class Days/Time: Classroom: Prerequisites: Dr. Ningguo Feng DH 554 (408) (924-4872) ngf@stanford.edu (temporary) subject: Bio107 Tuesday & Thursday: 8:30am 9:00am, 6:30pm-8:00pm Tuesday & Thursday 9:00am-10:15am DH 135 BIOL 3, organic chemistry and MICR 101 (all with a grade of "C" or better)

Faculty Web Page and MYSJSU Messaging Copies of the course materials such as the syllabus, major assignment handouts, etc. may be found on my faculty web page accessible through the https://ewok.biology.sjsu.edu/DrFeng User id: ewok\biostudents Password: 4biolecture Or, http://www.biology.sjsu.edu/course/kibler/Greensheet107.pdf You are responsible for regularly checking with the messaging system through. Course Description Provides information about all areas of immunology with emphasis on the basic concepts of immune mechanisms of the acquired and innate immune systems. Uses the basic information to study immune disorders and the immune response to infectious agents.

Required and recommended Texts/Readings Textbook The Immune System by Peter Parham, Third Edition, Garland Science. (required)

Dropping and Adding It is the student's responsibility to determine that they are enrolled in courses. Official enrollment in a course should be determined on 'My SJSU' or by confirming with the course instructor BEFORE the last day to add. No late or retroactive add forms will be approved in the department office after the last day to add. Students are responsible for understanding the policies and procedures about add/drops, academic renewal, etc. Information on add/drops are available at http://info.sjsu.edu/web-dbgen/narr/soc-fall/rec-324.html . Information about late drop is available at http://www.sjsu.edu/sac/advising/latedrops/policy/ . Students should be aware of the current deadlines and penalties for adding and dropping classes. Priority in decreasing order (1=highest priority): 1- Graduate Student 2- Senior 3- Junior 4- Sophomore 5- Freshman 6- Academic Renewal (Repeating) 7- Open University (non-matriculate)

Material posted on line:

Access: https://ewok.biology.sjsu.edu/DrFeng User id: ewok\biostudents Password: 4biolecture 1. Documents: Syllabi Reading project assigment Exam review sheets Homework assignments

2. Lectures in Power Point.

Assignments and Grading Policy Exam I (Feb 22) Exam II (March 22) Exam III (April 19) Exam final (May 24) Homework, 15% 20% 20% 25% 20%

No late examinations will be accepted without prior permission from the instructor.

Final grades:

Total grades: 100

A+ (96-100) A/A- (90- 95) B+/B/B- (80-89%) C+/C/C- (70-79%) D (60-69%) F (< 59%)

Exams include multiple choice questions

University Policies Academic integrity Students should know that the Universitys Academic Integrity Policy is available at http://www.sa.sjsu.edu/download/judicial_affairs/Academic_Integrity_Policy_S07-2.pdf. Your own commitment to learning, as evidenced by your enrollment at San Jose State University and the Universitys integrity policy, require you to be honest in all your academic course work. Faculty members are required to report all infractions to the office of Student Conduct and Ethical Development. The website for Student Conduct and Ethical Development is available at http://www.sa.sjsu.edu/judicial_affairs/index.html. Instances of academic dishonesty will not be tolerated. Cheating on exams or plagiarism (presenting the work of another as your own, or the use of another persons ideas without giving proper credit) will result in a failing grade and sanctions by the University. For this class, all assignments are to be completed by the individual student unless otherwise specified. If you would like to include in your assignment any material you have submitted, or plan to submit for another class, please note that SJSUs Academic Policy F06-1 requires approval of instructors. Campus Policy in Compliance with the American Disabilities Act If you need course adaptations or accommodations because of a disability, or if you need to make special arrangements in case the building must be evacuated, please make an appointment with me as soon as possible, or see me during office hours. Presidential Directive 97-03 requires that students with disabilities requesting accommodations must register with the DRC (Disability Resource Center) to establish a record of their disability.

Bio107 / Basic Immunology, Spring 2012, Tentative Course Schedule

Class # 1 2 3 4 5 6 7

Date 1/26/2012 1/31/2012 2/2/2012 2/7/2012 2/9/2012 2/14/2012 2/16/2012 2/21/2012

Class title Introduction Introduction/Lymphoid organs and cells Lymphoid organs and cells Innate immunity I inflammation Innate immunity II complement system Innate immunity III - pathogen recognition and signalling Review of lymphoid tissues and innate immunity Exam I B cell mediated immunity I antibody structure B cell mediated immunity II antibody strucure B cell mediated immunity III B cell response B cell mediated immunity IV T independent antigen B cell mediated immunity IV B cell development Antibody in therapy and biomedical research Review of B cell response Exam II T cell mediated immunity I T cell receptor and MHC Spring break Spring break

Reading Parham: Chapter 1 and 3 Parham: Chapter 1 and 3 Parham: Chapter 1 and 3 Parham: Chapter 2 Parham: Chapter 2 Parham: Chapter 2

8 9 10 11 12 13 14

2/23/2012 2/28/2012 3/1/2012 3/6/2012 3/8/2012 3/13/2012 3/15/2012 3/20/2012

Parham: Chapter 4 and 3 Parham: Chapter 4 and 3 Parham: Chapter 9 and 3 Parham: Chapter 9 and 3 Parham: Chapter 6 and 3 Parham: Chapter 4

15

3/22/2012 3/27/2012 3/29/2012

Parham: Chapter 5 and 3

16

4/3/2012

T cell mediated immunity II MHC and antigen presentation T cell mediated immunity III T cell activation T cell mediated immunity IV CD8 T cell activation T cell mediated immunity V T cell development Review of T cell response Exam III Mucosal immune response and vaccine Pathogen and immune system interaction Immune pathology and hypersensitivity Autoimmunity Organ and tissue transplantation Cancer immunity

Parham: Chapter 5 and 3

17 18 19 20

4/5/2012 4/10/2012 4/12/2012 4/17/2012 4/19/2012

Parham: Chapter 8 and 3 Parham: Chapter 8 and 10 Parham: Chapter 7

21 22 23 24 25 26 27

4/24/2012 4/26/2012 5/1/2012 5/3/2012 5/8/2012 5/10/2012 5/15/2012 5/17/2012 TBA

Parham: Chapter 10 and 14 Parham: Chapter 11 Parham: Chapter 12 Parham: Chapter 13 Parham: Chapter 15 Parham: Chapter 16

Final review

Finals