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Anti aging cream Review • Wadher et al, 2009 formulated and evaluated cream of Azadirachta indica leaves on skin renewal

rate. Three creams containing 0.5 %, 1.0 % and 2.0 % w/w of hydroalcoholic macerate extracts of leaves of neem were prepared. Creams were prepared in model FAPG base. Students t test shows that 1.0 % and 2.0 % hydroalcoholic macerate creams shows increase in skin renewal rate , which is significant at p<0.005 level of significance. While 0.5 % hydroalcoholic macerate extracts cream is significant at p<0.05 level of significance. • Bernantoniene et al, 2010 formulated and evaluated hydrophilic cream of Callendula officinalis (L.) with antioxidant activity. Different formulation with 0.3 %, 0.6% and 0.9% concentration of the extract were prepared. In case of the cream with 0.3% of Calendula extract was content of the active constituents low and weak antioxidant activity, the values did not differ from these of the cream base. Measured values of the active compounds in the cream with 0.9% of Calendula extract differed statistically significant (p < 0.05), therefore this cream was chosen for further microscopic evaluation and stability testing. This cream was then examined microscopically, and stability studies including evaluation of organoleptic properties, microbiologic quality and antioxidant activity.

Kamakaen et al, 2010 developed peacock flower extract as anti- wrinkle formulation. This study supports the traditional. The use of Caeselpinia pulcherrima (0.7% w/w) as an ingredient in cosmetic products with antioxidant and with antiwrinkle activity. The best effect was achieved by the ethanolic extract which corresponds to the traditional extraction practice. The results of DPPH radical scavenging assay showed the strongest activity (IC50= 34.74 μg/ml) of the crude extract from the red petals of C. pulcherrima, followed by the extract of the orange petals (IC50=35.63 μg/ml) and the yellow petals

SELS SEr (skin roughness). Formulation containing 3% of the concentrated extract of Basil was developed by entrapping in the inner aqueous phase of w/o emulsion and base contained no extract. energy and surface evaluation of the living skin (SELS). which represents its less-water-absorbing . Volume. 1 (average spreadibility 8.. volume. The ABTS cation radical scavenging assay demonstrated the strongest activity (IC50=227. The amount of phenolic compounds in term of gallic acid suggests that the flowers of C. 25°C. moisture and trans epidermal water loss (TEWL). The base showed insignificant (p≤0.8 ± 1.66 μg/ml) for the orange petals followed by the red petals (IC50=243. Significant effects (p≤0.72 μg/ml).01 μg/ml) and the yellow petals (IC50=338. Two formulas were prepared for cream base.38) as compared with Formula no. • Sabale et al. 1 showed a decrease in water number as compared with Formula no. Both creams were stored at different storage conditions of 8°C.27 μg/ml).22). pulcherrima may be a good source of natural antioxidants which may be incorporated into a range of cosmetics and health products. SEsc (skin scaliness). The effect of the Benincasa hispida fruit extract (5%) cream on skin renewal was evaluated. • Rasul et al. Formula no.4 ± 1.05) were observed for both creams in the case of TEWL. SEw (skin wrinkles) parameter showed significant decline while texture parameter of ‘Energy’ showed significant increase. The results show that Formula no.05) while formulation showed significant effects on skin moisture. 2011 formulated and evaluated topical antiaging preparation of fruit of Benincasa hispida. 40°C and 40°C+ 75% relative humidity to predict their stabilities. 2 had good spreadability (average spreadability 18.e. SEsm (skin smoothness).aging effects of an emulsion containing basil extract using non-invasive biophysical techniques.(IC50=102. 2. 2011 formulated and evaluated anti. A single blinded study was conducted using non-invasive methods. The formulation and base were evaluated for their effects on various skin parameters i. respectively.

35 ± 0.05) effects while the formulation decreased TEWL however this decrease was statistically insignificant (p> 0.07) than Formula no. 2 showed good diffusibility (average diffusibility 2. It is safe and stable too. The Draize test for sensitivity testing has shown that the stable formulations are safe in respect to skin irritation and allergic. Skin sebum was significantly (p_0. Samples were stored at different storage conditions that is.05). Formula no.05 ± 0. The formulated turmeric based herbal face cream is a cosmeceutical that contains quantified amount of curcuminoids. • Sahu et al. 40°C+75% RH for four weeks to predict their stability.type of emulsion.0 ml vs. The base showed insignificant (p>0. Both creams were aesthetic with respect to sensory evaluation. 2 was found to satisfy all the desirable properties of oil-inwater cream base and was decided to be the final cream base. 2011 evaluated various functional parameters using a topical cream of Calendula officinalis extract. The newly formulated base and formulation were applied to the cheeks of 21 healthy human volunteers for a period of 8 weeks. 2011 formulated and evaluated curcuminoid (2% w/w) based herbal face cream. Skın erythema was significantly reduced by the formulation. Base without active and formulation having 3% extarct of calendula in the aqueous phase were prepared. Evaluation of formulated cream with parameters .capacity (3.05) decrease in skın melanın content. 1 (average diffusibility 1.0 ml). 40. The base showed insignificant (p>0. . 25. The topical noninvasive application of Calendula officinalis cream showed a positive rejuvenating effect on human skin. ashing at 600 oC. Formula no. 8. Skin moisture content was significantly (p_0. pH. 2.05) incresaed by both creams (base and formulation). homogeneity and sensory parameters has been conducted.05) effects while the formulation showed statistically significant (p_0. 4 out of 16 products have shown stability with no signs of bleeding and no change in the color of the product.05). Accelerated stability testing of 16 prepared formulations has been conducted at elevated temperature of 40 oC ± 1oC for 20 days.05) increased by the formulation. • Akhtar et al. Thus.

erecta obtained the SPF 8. Both the base and formulation were stored at 8°C0. arbortristis sunscreens will enhance and significantly contribute to the UV absorbing properties of conventional sunscreen formulation. It will also help in broadening the UV protection ability of the sunscreen along with the greatest advantage of avoiding the adverse and undesired effects of synthetic sunscreen compounds.1°C and 40°C0.35.1°C. The study was designed to formulate and evaluate antı-agıng effects of a topical cream (water in oil (w/o) emulsion) containig extract of milk thistle (Silybum marianum) against its vehicle (Base) as control. The sunscreen cream containing ethanolic extract T.21±2. we can positively conclude that N.(1% w/w) and Tagetes erecta L.(1% w/w). liquefaction and pH. Base containing no extract and a formulation containing 4% concentrated extract of Silybum marianum was developed by entrapping in the inner aqueous phase of w/o emulsion. • . 2011 studied the sunscreen activity of herbal cream containing flower extracts of Nycanthes arbortristis L. smell. • Rasul et al.1°C with 75% RH (in incubator) for a period of 8 weeks to predict their stability.aging potential of a cream containing milk thistle (Silybum marianum) extract. From the result obtained in the study. arbortristis under study produced high absorbance at 290-320 nm wavelength range and SPF obtained was 10. 2012 formulated and evaluated anti. The in vitro SPF of the formulations was determined according to the UV Spectrophotometric method of Mansur et al. electrical conductivity. The evaluation parameters consisted of colour. 40°C0.1°C (in refrigerator). type of emulsion. 25°C0.• Bambal et al.18. The sunscreen cream containing ethanolic extract of N.67±1.