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NEWS LETTER OF ARMARC

AUGUST -2011 Editorial Oxford dictionary defines astrology as study of supposed planetary effects on human affairs. When such effects are related with health, naturally it comes to matter of medical-astronomy. Today even modern science has started to realize and work on such possible effects what Indian saints had already dealt hundreds of years back. “Aryabhatt” from Pataliputra (modern Patna) observed the elaborated relation of these planets with human bodies and tried to prove the facts with calculations of mathematics. Taittriya Brahmana and Bhrigu-samhita were already in practice that time even for the purpose of related aspects of astrology. Numbers of creations have exposed the relations of human affairs with planets, constellations etc. With proper understanding and calculations of relations among the planets under certain signs (rashis) in respect to constellations, almost correct speculations can be given. Only birth details including date, time, place etc. should be perfect. It also renders ideas regarding possible ailments to bodies with degree of occurrence and their cures, like any drug which may enhance the immunity to combat the evil effects of existing or forthcoming diseases is preferred to be given in Pushya nakshatra according to medical astronomy. This particular nakshatra is ruled by Brihaspati, the god of divine wisdom which gives ability to create spiritual energy (brahmavarchasa shakti) or will power and it is directly related with immunity or combating capacity against evils of bodies. Other than these, all plants are assigned with certain nakshatra and individual medicinal plant has maximum potency in that particular nakshatra. Again for combination of herbs in any formulation, it may depend upon the dominance of particular component and accordingly the nakashtra. Vol 2.10 All these planets, constellations etc. are bundles of elements with various proportions and certainly they emit energy, known as cosmic energy. Not only human bodies, but everything on this earth has life-long effect of such energies once they come in to existence. These effects start at molecular level. In living being, the constitution of body at molecular level also happens in accordance with these energies. The good or bad effect of such energies with their frequency also depends consequently. Whenever the body comes in contact with familiar energy received while in process of constitution, accordingly it is reflected with good or bad effect. Any mistake with understanding or calculation may give rise to false perception. Earlier our vaidyas used to provide the medicines keeping all these aspects in mind. A detailed scientific proof after exhaustive study on these aspects may bring a new boon where all diseases can be treated with simple medications and, health by all means of body, mind and sprituality can be achieved easily.

HAPPY INEPENDENCE DAY 15th August, A MOST SACRED DAY FOR EVERY CITIZEN OF INDIA In This Issue
1) An Insight into the concept of
Atattwaabhinivesham 2) Pharmacognostical evaluation of Yavani (Trachyspermum ammi (L.) Sprague)

3) Formulation Profile (Series-A/31) Sadbindu Taila 4) Herbal Drug Profile (Series-A/32) Kantakari

Raghvendran. Like and dislike are inter-related. is manifested. Ayurved Mahavidyalaya. Even in nidana sthana no references have been quoted in context of apasmara. First. All the other scholars of Ayurveda of Samhita period including Sushruta and Vagbhatta did not describe this disease. its thorough knowledge is the need of time since long past. as being highlighted in samprapthi is “alpa satwa”. there is ignorance. Agnivesha particularly raises this topic for discussion with Atreya at the end of apasmara chikitsa. If the context of discussion is closely scrtutinized. Wherever there is pain. Asmita. If Raga is attachment to objects. PG Scholar. D. The pathogenesis gradually seeps through physical and metaphysical domain of existence and vice versa. Asmita (egoism). ALNRMAMC.Newsletter of ARMARC 2 AUGUST -2011 An Insight into the concept of Atattwaabhinivesham Dr. Anxiety neurosis etc. Somit Kumar. there is Dwesha. he straightway refused its description in Chikitsa Sthana saying it as ‘Anarsha’ means edition of its text by someone else in later period. PG Scholar. Raga-Dwesha is also one of the important afflictions.Owing to this confusion and lack of detailed description of this disease. In this state of alpa satwa any endogenous (humeral . As a result. The five afflictions are Avidya (ignorance). Visualizing the samprapthi of unmada and apasmara we come across a major distinction. he is subject to sorrow and depression. OCD. While in Sutrasthana he described Atattvabhinivesha as ‘Eko Mahagada’ means the colossal disease. memory etc. of Kayachikitsa. He allows the mind to dominate him. Koppa Dr.It means disarranged corporeal tridoshas altering the balance in psychic humours rajo and tamo gunas and vice versa. Abhinivesha. and from Raga-Dwesha. In Unmada higher metaphysical faculties like psyche. Hubli While discussing the spectrum of Psychic and neo-psychic disorders we come across a condition termed as Atattwaabhinivesham. once in charaka sutra sthana 19th chapter while elaborating on number of samanyaja vikaras and then in charaka chikitsa at the end of apasmara treatment. according to Patanjali Maharshi. Dept. are altered or afflicted. Dept. or clinging to this life or fear of death . Atattvabhinivesha is a minor psychological ailment and it resembles with neurotic disorders of modern psychiatry particularly anxiety states. It has been always topic of deliberation. of Dravyaguna. Raga-Dwesha (like and dislike) and Abhinivesha (clinging to life). The prerequisite. From this is born egoism. The nidanas of atattwaabhinivesha in terms aahara and vihara seem to be almost alike apasmara and unmada. intellect. Before we discuss the samprapthi of these three disorders I would like to elaborate upon few conceptions. the original Avidya. and from Asmita is born Raga-Dwesha. Charaka has mentioned mahagada or atattwaabhinivesham twice. as to what is significance of atattwaabhinivesha and its relevance now both conceptually and clinically. there is Raga. Psychiatric disorders or neo psychiatric disorders like unmada and apasmara manifests through somatic plane to psychic plane and vice versa . Abhinivesha makes a man attached to samsara (worldly concerns) and to forget his real destiny. Apasmara and unmade tends to engross the realms of body. it is wonderful to find about its relevance in apasmara chikitsa and not in unmada . Wherever there is a little pleasure. mind and higher intellect in a different way and intensity.

. plane. pratishyaya etc. Koppa Apasmara.Newsletter of ARMARC 3 AUGUST -2011 imbalance in vatadi doshas) or exogenous (grahas or extra sensorial entities) mask or overshadow or alter the Pharmacognostical evaluation of Yavani (Trachyspermum ammi (L. The status of mind without being alpa in book Textbook of Pharmacognosy. Vatari. deepana. Brahm Darbha.E.dusta aahara.) Sprague) Dr. predominantly involves the somatic or physical corporeal Bhoomi. Sukumara taila. Tikshna.Dipya. Guna: Laghu. Hridhya. RS&BK. The pathogenesis and imbalance are rooted Ajawain. They were studies macroscopically and microscopically by the method suggested by T.) the faculties of sense organs. Agnigandhi. Fragments of essential oil was collected after running with column chromatography. Q. aggravates the physical doshas and influence the rajo Ajmodadi churna.So it may be subclinical phase of unmade different formulations viz. Kharhwa. intermittently on metaphysical or Psycho-sensory plane Rukshna.samsarjanadi karma and tests for phytochemicals were done by methods menmedhya rasayanas are recommended . Panchkoladi ghrita. jwara. The collected to unmade. ALNRMAMC. Kanchan Kulkarni. The chikitsa has been recommended to prevent mind getting procedures given in British Pharmacopoeia were used feeble . Pathogenesis of apasmara Dipaniya. If this condition left untreated it will slowly lead for the purpose. mind. Clinically mimic unmade but pathogenesis is still (dried) was collected from the cultivated field in Bhagalpur corporeal (tridoshas vatadi dominant) influencing the district of Bihar. it is condition sothahara. The preliminary satwa. Laboratories. So sodhana chikitsa . material was done with phytochemical tests and then with ***** thin layer chromatography pure thymol was collected.C. a transient state of vitiated tamas overcastting Botanical source: Fruits of Trachyspermum ammi (L. just before a somatic disease becomes established at Yavani is used as one of important component of psychic plane . Yavanikadi and tamo guna of mind due to its sukshma sara reaching kada etc. Virrudha aahara. transiently influencing the sensorial and psychic Bhokadamba. Hilahula. Lata oshadhi. visha dosha. innate or usual psycho-social characteristics of patients. Bobiyika. Yavagraja. associated with vibhatsa chesta or involuntary clonic Synonyms: Yavani. Sudarshana churna. Satyadi gutika. Takrarishta. Dipyaka. Sholahantri. Yavasahwa. Head. Yavani satva. Virya: Ushna. Yavanikadi kwatha. predominantly at somatic or physical body but expressed Rasa Panchaka: Rasa: Katu. Yavahwa. Agni Vardaka. Prashant Kumar Jha. PG Scholar. Anurasa: Tikshna. Ajagandha. and tonic spasm of the limbs. Now let us understand come to the concept of kusthaghna. chhardi. pachana. Yavanikadi state. Hingvastaka churna. rochana. sosha. Ksetra yavani.Satwajaya tioned by Trease and Evans’s Pharmacognosy. vega rodha churna. under various vargas for various proeprties like krimighna. The quantitative data was collected after the experiments. Ugra. Materials and Method: The drug ready for marketing mind. Wallis faculties of psyche. In simple words. Ywavanika. atattwaabhinivesham. Yogaraj guggulu. Tivra Gandha. Dept. Ajmodha. Dr. Vipaka: Katu as vegas(episodes) when the doshas vitiates beyond Yavani is an important ayurvedic drug mentioned in almost all Nighantus and other prominent ayurvedic texts threshold . Bhootika.. intellect and memory Sprague from family Apiaceae. plane. Ugragandhi. kaphaghna.

They are internally lined with epithelial cells. The detailed section reveals the epidermis covered with striated cuticle as outermost cells followed by parenchyma cells in mesocarp.3 mm long and 1-2. They are traversed with vitta. Flowers are whitish or pinkish whilein umbelliferous inflorescence. Odour is characteristic thymol type while the taste is slightly bitter pungent. Macroscopy Macroscopy: The fruits are ovoid. Mericarps are usually separated. a special type of cell secreting essential oil. They are in 2 indehiscent laterally compressed mericarps. 12. They are ovoid to conical in shape. The segments of leaves are narrowly linear and glabrous. compressed with pale coloured short protuberances. The dorsal surface of each mericarp is with five distinct primary ridges. Outline of TS (Transverse section) Microscopy: The outline of the transverse section shows Outline of A fragment of complete section .1 mm wide. These mericarps are attached with carpophore. Embryo lies almost in centre of endosperm. The minerals were quantitatively determined using flame photometer and titrimetric methods using procedures given with Pharmacopoeial Standards of Ayurvedic Formulations. greyish-brown. Fruits arehispidulous and prominently ridged. The broader portion of the seed is covered with endosperm.Newsletter of ARMARC 4 AUGUST -2011 each mericarp with four large vittae on dorsal surface and two on commissural surface. Four primary ridges are present on dorsal surface. Some vascular cells are also present in this region. Result: Plant Morphology: This is a up to 60 cm tall slender herb with pinnately decompounds leaves.

Newsletter of ARMARC 5 AUGUST -2011 Fibres of Carpophore Epicarp and mesocarp Surface view of epidermis with striated cuticle Vessels Vitta (Essential Oil Secretory Gland) .

65% : 13.21 % : 2. ***** . Preliminary Phytochemical Tests: Phytochemicals Carbohydrate Protein Tannin Glycoside Terpenoids Alkaloids +: Traces Physicochemical Parameters: Total Ash Acid Insoluble ash Water soluble ash Alcohol soluble extractives Water soluble extractives Quantitative Assessment of Phytochemicals: Carbohydrate Protein Fat Essential Oil Thymol Minerals Calcium Potassium Soidum Iron : 1.21% : 0.87% : 19. fragments of endosperm composed of thick-walled polygonal cells containing aleurone grain etc.51% : 1.71% : 22. The odour is characteristic while taste is slightly bitter.33% : 7.63% of total essential oil : 7.97% : 18.55% : 43. parenchyma cells of mesocarp.11% : 3.48% : 2.The powder is yellowish-brown in colour and shows cells of epicarp exhibiting characteristic striations.Newsletter of ARMARC 6 AUGUST -2011 Powder.12% : 3. fragments of yellowish-brown vittae. Fragments of trichomes. are present.41% ++: Average Inference +++ +++ ++ +++ +++ + +++: Moderate Conclusion: This is an important drug and commercial spice with lot chances to be exploited for number of other constituents and their pharmacoloical uses.

Aja milk 3. Fracture is short to slightly fibrous.75% : 4. Jivanti root 6. Geographical Source: It is found throughout India specially in deciduous forest area to semi arid zone. Seeds are sub-spherical and compressed with bitter and acrid taste. tapering with wrinkles and scars on surface. yellow or orange when ripe. Tehpatra leaf 11. They are spherical to globular in shape and are filled with seeds. Flowers are light to deep purple in colour and in extra-axillary racemes. Prashant Kumar Jha Botanical Source: Whole plant of Solanum xanthocarpum Schrad. pinnatified. Vidanga fruit 12.5 cm across.4671 : 194. K. yellowish-brown and minutely rugose. spherical.22 : 4.5 cm in size. Satavha fruit 13. Fracture is short and taste bitter.12 Dose : Quantity sufficient Therapeutic Indication: Externally applied for nasya.S. Sunthi rhizome 10.07 gm Herbal Drug Profile (Series-A/32) Kantakari Prof. pinnatified and petiolate. Description: It is brownish-red oil with characteristic pleasant odour.53% : 2.Mishra Dr. Leaves are hairy with full of sharp prickles along the veins and veinlets. Leaves are 2-12 x 1-7. Tila oil 2. Loss on drying at 110° C Total ash Acid insoluble ash Refractive index Saponification value Iodine value Acid value : 0.14% : 1. from family Solanaceae.Vidyasagar Dr. Macroscopy: Roots are cylindrical. Seeds are sub-spherical. Erand root 5. They are ovate. compressed.Newsletter of ARMARC 7 AUGUST -2011 Formulation Profile (Series-A/31) Sadbindu Taila Prof: D.Sanjay Dr. Saindhava lavana 19 gm 19 gm 19 gm 19 gm 19 gm 19 gm 19 gm 19 gm 19 gm 19 gm 768 gm 3. They are externally greenish-yellow in colour and often with hollow pith. Yastimadhu root 8.07 gm 4. Plant Morphology: It is bushy stellately pubescent diffused or procumbent armed undershrub. Tagara rhizome 9.K.32 : 96.Prashant Kumar Jha Dr. M. Bhringraj whole plant 3. general debility. Fruits are surrounded by persistent calyx and yellow coloured. abyanga etc. Throny or prickly stems are enveloped with minute hairs. mental disorders etc. Rasna root 7. Berries are 1-1. & Wendl. (Reference: Bhaisajyaratnawali: Shirorogadhikar) Ingredients: 1. Hari Venkatesh Prof. Somit Kumar Niranjan J. . to improve eyesight.

Quality Control Laboratories. ALN Rao Memorial Medical College. On producing the card. at nominal charges Contact: Dr. Somit Kumar Printed and Published by ARMARC on behalf of Honourable A. Note: All original scientific papers are invited from the works of scientific field. Standardization of Single as well as Compound Drugs. solasonine.Newsletter of ARMARC 8 PRINTED MATTER/BOOK POST AUGUST -2011 Chemical Constituents: Fruit is having carpesteral.com . • According to The FASEB Journal. District-Chikmagalur. used in cough. DIM. prashantjha19@rediffmail. 1000) OVERSEAS USD 10 Membership fees. RNI. special discount can be availed on ARMARC publications. DD or Crossed Cheque addressed to Principal. each member will be issued a receipt and a membership card.Vidyasagar Co-Editor: Dr. Chikmagalur Dt. India (No. PGDEE. Photomicrograph etc.com. • Journal of Leukocyte Biology suggests that two frequent mutations in an immune system gene called TLR1 are responsible for cellular changes that ultimately makes us less likely to resist the diseases. KARENG/2002/7924 COME! JOIN THE ARMARC NETWORK New Reseacrhes In Medical Science • A study at Harward school of public health suggests that even a little excercise may reduce the rish of coronary heart disease.577 126. M. Mob: 09742424407 URL:www. solamargine. Ph.alnrmamc. KARENG/2002/7924. Karnataka . Flame Photomeneter. Uses: Root is expectorant. Petals yields apigenin while stamens quercetin and sitosterol. may be sent by MO. Ramesh Rao. solanocarpine and solasodine.577126. On receipt of the fees. flowers and fruits are bitter and carminative. Prashant Kumar Jha CIPR. New Delhi) email: prashantjha19in@yahoo. Mail (Post/E-mail) us. both of which should be preserved carefully. Aroor Ravi Memorial Ayurvedic Research Centre Patron Honourable A. The receipt number and the membership number should be referred to in all transactions. Once Published paper is under the copyright of Newsletter. nicotine protects us from Parkinson’s disease through alpha-7 nicotine receptor.) M. Ramesh Rao Editor: Prof (Dr.co.in. INDIA Student(Rs. Koppa. Stems.. which includes an annual subscription to the newsletter.D. the plant may be useful in bronchial asthma. 100). Institution(Rs. ALN Rao Memorial Ayurvedic Medical College. Karnataka . Leaves are locally applied with bacl pepper for rheumatism. The whole plant contains around 3-4 % of alkaloid while diosgenin is also reported from whole plant.Prashant kumar Jha Research Coordinator: Dr. Individual(Rs. For All Pharmacopoeial Analysis. 150) Patron (Rs. 50). asthma etc.Sc. RNI Regd No. Koppa. Koppa Your Suggestions and Queries are invited. with Spectrophotometer. The membership is to be renewed each year and the new receipt number noted on the membership card by each member. Both glycoalkaloidal and fatty acid fractions of plant are histamine liberator and due to depletion of histamine.