Drug Study
Drug Name Diazepam 4.2mg IV  Anxiolytic  Antiepileptic  Skeletal muscle relaxant  Benzodiazepine Mechanism of Action  Acts mainly at the  limbic system & reticular formation; may act in spinal cord and at the supra-spinal sites to produce skeletal muscle relaxation  The drug is a  member of benzodiazepine tranquilizers which exerts anxiolytic, sedative, muscle relaxant, anticonvulsant and amnesic effects; potentiates the effects of GABA.  General CNS  depressant; barbiturates inhibit impulse conduction in the ascending RAS, depress the Indications Muscle Relaxant:  Adjunct for relief of skeletal muscle spasm due to local pathology (inflammation of muscles or joints) or 20 to trauma. Antiepileptic: Adjunct in status epilepticus and severe recurrent convulsive seizures. Contraindications Adverse/Side Effects Contraindicated with The most common hypersensitivity to reported adverse benzodiazepines; effects are: psychoses, shock,  Fatigue coma, acute alcoholic  Drowsiness intoxication,  Muscle pregnancy, and weakness lactation. Nursing Responsibility  Practice the 10 R’s of drug administration  Maybe taken with or without food  Monitor liver and renal function  Caregiver should report severe dizziness, weakness, drowsiness, and rash or skin lesions, palpitations, and dysuria.

Phenobarbital 35mg IV q120  Barbiturate  Sedative  Hypnotic  Antiepileptic

Indicated for the  treatment of generalized tonicclonic and cortical  focal seizures and emergency control of

Contraindicated with  hypersensitivity to barbiturates. Use cautiously with seizure disorders (abrupt

Confusion, lethargy,  hallucinations, nausea, vomiting,  rashes, stevenjohnson syndrome, hypoventilation, 

Practice the 10 R’s of drug administration The drug will make the patient drowsy and less anxious Do not reduce or

has anti-seizure activity. petechiae. discontinue(abrupt discontinuation could result in serious increase in seizures. rash or skin lesions. depress motor output. neutropenia. making it suitable for long term use as an antiepileptic. fever. myocardial damage. discontinuation of daily doses can result in status epilepticus). weakness. easy bruising or bleeding. hypnosis. anuria. hematuria. nosebleed.      . dyspnea. unusual bleeding or bruising. alter cerebellar function. dizziness that persists. thrombocytopenia. hypoglycemia. Hepatic toxicity and failure.  other viral and bacterial infections with pain and fever  Contraindicated to  clients with allergies to acetaminophen. Practice the 10 R’s of drug administration Give drug with food if GI upset occurs Discontinue the drug if hypersensitivity occurs. yellowing of eyes or skin and changes in Common cold. anesthesia. Reduces fever by  acting directly in the hypothalamic heatregulating center to cause vasodilation and sweating which help dissipate heat. bronchospasm. flu. pancytopenia. acute renal failure. sedation. fever. laryngospasm. acute seizures. Headache. respiratory depression. Rash. circulatory collapse. mouth sores. and produce excitation. sore throat. and deep coma. chest pain. at subhypnotic doses. apnea. jaundice.  withdrawal syndrome. Give the drug only for complains evident Report rash. leucopenia.Paracetamol 140mg IV q40  Analgesic  Antipyretic  cerebral cortex. Use caustiously with impaired hepatic function. Report severe dizziness.

bleeding. drowsiness. steven-johnson syndrome. mental confusion. malaise .      voiding patterns. group 1b  Hydantoin  Has antiepileptic  activity without causing general CNS depreesion. CV collapse. diabetes mellitus. liver damage. except on the advice of the health care provider Maintain good oral hygiene (regular brushing) to prevent gum disease Report rash. gingival hyperplasia. SLE. yellowish discoloration of eyes or skin. limits the spread of seizure activity from an active focus. stabilizes neuronal membranes and prevents hyperexcitability caused by excessive stimulation. Document every abnormal or unusual effects after drug administration. Indicated to control  grand mal and psychomotor seizures. slurred speech. hyperglycemia. swollen glands.  Contraindicated with  hypersensitivity to hydantoins. dizziness. Slurred speech. nausea. Practice the 10 R’s of drug administration May give with or without food Do not discontinue drug abruptly. tender gums. sinus bradycardia. Phenytoin 6mL PO q120  Antiepileptic  Antiarrhythmic. severe nausea and vomiting. fever. drowsiness. Use cautiously with hypotension. impaired coordination (ataxia). severe myovardial insufficiency. stokes-adams syndrome. sinoatrial block.

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