MicroVacuum

Integrated Optical Chemical and Biochemical Sensors

presents

OW 2400
OPTICAL WAVEGUIDE GRATING COUPLER SENSOR CHIP

Grating Dot mark

TECHNICAL SPECIFICATION
I
W
Diffraction grating
F (waveguide film ) Surface relief structure:
S (substrate glass )
depth~20 nm
H Grating periodicity:
L 2400 lines/mm (0,4166 µm)
Grating area dimensions:
length ( l )~2 mm
Introduction width (w)=16 mm
The optical grating coupler sensor responds to the Grating lines direction:
change of optical refractive index of the liquid or parallel to the short edge of the sensor chip
gas cover medium and to the adsorption or binding Dot-mark:
of molecules on the surface. diffraction grating is uppermost, when dot mark or
number is in the upper right corner
The optical grating coupler sensor chip is based
on a fine optical grating prepared on a thin
waveguide layer carried by a glass substrate. The Planar monomode waveguide
optical grating couples the light of a He-Ne laser Waveguide material (SOL-GEL)
at a given resonance angle into the waveguide SixTi(1-x)O2 , where x=0,25±0,05
layer. This incoupling angle is very sensitive to the
presence of adsorbed molecules and to any Waveguide film
change of refractive index of the medium covering refractive index (nF)=1,77±0,03
the surface of the chip. By precise measurement thickness (dF)=170-220 nm
of the incoupling angle, the amount of the
adsorbed material can be determined with ultra Substrate glass slide
high sensit ivit y. length (L)=48 mm
width (w)=16 mm
OW 2400 sensor chips are used in high-resolution thickness (H)=0,55 mm
optical waveguide lightmode spectroscopy (OWLS). refractive index (nS)=1,53
Other substrate sizes are available on request.
Main biosensing applications
• Adsorption of proteins at surfaces
• Ligand/receptor binding (antibody/antigen) Non biosensing applications
• Immunosensing • Excitation of fluorescently labeled probes
• Drug screening • Incoupling laser light for total internal reflection
• Protein - lipid bilayer interactions • Incoupling laser light for Raman spectroscopy
• Protein - DNA interactions • Incoupling laser light for optical loss measurement in
• Molecular self-assembly & nanoscience thin films
• Analysis of association and dissociation kinetics • Incoupling laser light for SPR measurement
• Kinetics of adhesion, growth and spreading of • In situ monitoring and characterization of nanometer
animal cells scale thin layers
• Food monitoring • Humidity and gas monitoring

MicroVacuum Ltd.
Kerékgyártó u. 10., Budapest, H-1147, Hungary ; Tel: +36 1 252 1991; Fax: +36 1 221 7996
E-mail: info@microvacuum.com; Web: http://www.microvacuum.com/