Script – The Cell Cycle

INT. White Room with Roger Matthews, CEO of SCI-CORP. CAMERA ZOOM IN (SLOW) Roger Matthews:

by Nicholas Baker

“Hello, I’m Roger Matthews CEO and voice of SCI-CORP, you may have heard of me from such educational films as ‘How to prepare yourself with biology and communism’ and ‘Hey, Science is Fun, Ok”. “On today’s educational film I will be taking you through the dangerous process of a cells journey within the Cell Cycle”. “Let’s begin shall we”.

Act 1:
INT. To the cells getting ready for the Cell cycle. Goes into a short intro for a brief moment where it shows the company ‘SCI-CORP’ and the title “The Cell Cycle and You”. With a type of 1950’s educational feel to it. After the intro it then goes into the 3D as we see a cell approaching the G1 to start the Cell Cycle. (Roger Matthews narrates at the same time). Roger Matthews: “When cells are ready to divide they go through The Interphase. The Interphase consists of stages that a cell must pass through. The first stage is known as G1, this is where cells start to grow as they approach the G1 checkpoint”. CAMERA CUTS TO: G1 CHECKPOINT The cell then approaches the G1 checkpoint as one by one the cells go through the checkpoint with no problems what so ever. CAMERA: FOLLOWS ONE OF THE CELLS Roger Matthews: “Ah I see the cells are lining up for the first checkpoint. Now remember if a cell has not fully grown and not ready for the synthesis stage of the cell cycle, they won’t be allowed to go through the checkpoint to finish the cycle”. CAMERA CUTS TO A FAULTY CELL

One of the cells approaches to the G1 checkpoint as it looks different and is not complete or ready for the G1 checkpoint to continue the cycle. Roger Matthews: “Oh oh, looks like we have a cell that’s not ready for the next stage”. CAMERA: CUTS TO G1 CHECKPOINT The faulty cell reaches the G1 checkpoint as the gate closes and the cell is taking away by security cells off screen. As the gate reopens and other cells pass through. Roger Matthews: “Looks like this little guy is going to have a bad day. Ha ha ha. But don’t worry folks this faulty cell will be handled with care to be restored to join the ranks of the other cells in due time”. Gun “BANG!” Roger Matthews: “Let’s move on shall we”.

Act 2:
CAMERA: CUTS TO SYNTHESIS STAGE The cells now still will start the duplication of the chromosomes within the cell’s nucleus as the duplication of the DNA begins. Roger Matthews: “Now we move onto the Synthesis stage of the Interphase. This is the stage where cells are now ready for the chromosomes to duplicate its DNA. Look at them little fellas go, really something huh”. CAMERA: CUTS TO G2 STAGE After the cells chromosomes have finished duplicating the DNA the cells continue through the cycle as they go through the G2 stage where they are preparing for Mitosis. CAMERA: PANS ALONG SIDE THE CELLS Roger Matthews: “Now the cells have successfully duplicated there chromosomes they can now pass through the G2 stage where they will meet another checkpoint to be assessed, similar to the G1 stage but in this stage they are preparing for Mitosis instead”. As the cells approach the checkpoint all the cells pass through onto the next step where the cells now divide through the steps of Mitotic Phase.

Act 3
Roger Matthews: “Good work soldiers no problems passing through this checkpoint, must be American cells ha ha ha. We will know watch the wonders of the cells dividing as they go through the Mitotic Phase. The Mitotic phase consists of five stages the Prophase, Prometaphase, Metaphase, Anaphase and Telophase”. CAMERA: FULL SHOT OF A CELL A cell is now in the centre of the screen spinning very slowly as it goes see through and starts the ‘Prophase’ stage. Roger Matthews: “This is the Prophase stage where the chromosomes start to split to form two sister chromatids”. The cell then moves onto the Prometaphase (camera still on full shot of the cell). Roger Matthews: “We now move onto the Prometaphase The cell’s nucleus envelopes as the centrosomes have now moved to either side of the cell where the spindle fibres connect with one another around the sister chromatids”. The cell then moves onto the Metaphase (camera still on full shot of the cell). Roger Matthews: “This is the Metaphase, the sister chromatids then line up beside each other which is called the metaphase plate just before they split. The cell then moves onto the Anaphase (camera still on full shot of the cell). Roger Matthews: “In the Anaphase the sister chromatid then split from one another now called ‘daughter chromosomes’ as they head to other side of the cell”. The cell then moves onto the last phases known as the Telophase (camera still on full shot of the cell. Roger Matthews: “Now here comes the tricky part, in the Telophase the cells start to split which is called the cleavage burrow as one cell forms a nucleus were as the other cell will form a nucleolus. CAMERA: CUT TO END OF MITOTIC PHASE The camera follows both cells as one heads towards the interphase and the other heads out of the interphase.

Roger Matthews: “After the Mitosis the cells division is now complete, the cell with the nucleus head back into the interphase to repeat the process as the cell with the nucleolus heads away from the interphases”.

INT. White office with Roger Matthews, CEO of SCI-CORP CAMERA: CUT TO ROGER MATTHEWS End of animation back to Roger Matthews in the white room. Roger Matthews: “And there we have it folks the wonders of the cell cycle. Unfortunately were out of time and we hope you have enjoyed this educational film directed and edited by SCI-CORP to help you know what’s what about how your body works. I’m Roger Matthews and remember love science, goodbye now”. CAMERA: ZOOMS OUT SLOWLY The documentary ends with the film cutting out like it was damaged.


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