lR;eso t;rs

Directorate General of Health Services Ministry of Health & Family Welfare Government of India

Contents
List of Participants Preface to National List of Essential Medicines 2003 Preface to National Essential Drugs List 1996 List of Additions List of Omissions List of Drug Movements Across Categories Therapeutic Categories List of Essential Medicines 1. Anaesthetics 1.1 General Anaesthetics and Oxygen 1.2 Local Anaesthetics 1.3 Preoperative Medication and Sedation for Short Term Procedures 1.4 Postoperative Respiratory Stimulant Analgesics, Antipyretics, Nonsteroidal Antiinflammatory Medicines, Medicines used to treat Gout and Disease Modifying Agents used in Rheumatoid Disorders 2.1 Non-Opioid Analgesics, Antipyretics and Nonsteroidal Antiinflammatory Medicines 2.2 Opioid Analgesics 2.3 Medicines used to treat Gout 2.4 Disease Modifying Agents used in Rheumatoid Disorders Antiallergics and Medicines used in Anaphylaxis Antidotes and Other Substances used in Poisonings 4.1 Nonspecific 4.2 Specific Anticonvulsants/Antiepileptics Antiinfective Medicines 6.1 Anthelminthics 6.1.1 Intestinal Anthelminthics 6.1.2 Antifilarials 6.1.3 Antischistosomals and Antitrematode Medicines 6.2 Antibacterials 6.2.1 Beta Lactam Medicines 6.2.2 Other Antibacterials 6.2.3 Antileprosy Medicines 1 1 1 1 2 2 2 2 2 3 3 3 3 4 4 5 5 5 5 5 5 5 6 7 i ii v viii x xi xii

2.

3. 4.

5. 6.

6.3 6.4

6.2.4 Antituberculosis Medicines Antifungal Medicines Antiviral Medicines 6.4.1 Antiherpes Medicines 6.4.2 Antiretroviral Medicines* 6.4.2.1 Nucleoside Reverse Transcriptase Inhibitors 6.4.2.2 Non-nucleoside Reverse Transcriptase Inhibitors 6.4.2.3 Protease Inhibitors Antiprotozoal Medicines 6.5.1 Antiamoebic and Antigiardiasis Medicines 6.5.2 Antileishmaniasis Medicines 6.5.3 Antimalarial Medicines 6.5.3.1 For Curative Treatment 6.5.3.2 For Prophylaxis 6.5.4 Antipneumocystosis and Antitoxoplasmosis Medicines

8 8 9 9 9 9 9 9 10 10 10 10 10 11 11 11 11 11 12 12 12 13 14 14 14 14 15 15 15 15 16 16 16 17 18 18 18 18 18 19 19 19

6.5

7.

Antimigraine Medicines 7.1 For Treatment of Acute Attack 7.2 For Prophylaxis Antineoplastic, Immunosuppressives and Medicines used in Palliative Care 8.1 Immunosuppressive Medicines 8.2 Cytotoxic Medicines 8.3 Hormones and Antihormones 8.4 Medicines used in Palliative Care Antiparkinsonism Medicines Medicines affecting the Blood 10.1 Antianemia Medicines 10.2 Medicines Affecting Coagulation Blood Products and Plasma Substitutes 11.1 Plasma Substitutes 11.2 Plasma Fractions for Specific Use Cardiovascular Medicines 12.1 Antianginal Medicines 12.2 Antiarrhythmic Medicines 12.3 Antihypertensive Medicines 12.4 Medicines used in Heart Failure 12.5 Antithrombotic Medicines Dermatological Medicines (Topical) 13.1 Antifungal Medicines 13.2 Antiinfective Medicines 13.3 Antiinflammatory and Antipruritic Medicines 13.4 Astringent Medicines 13.5 Medicines Affecting Skin Differentiation and Proliferation

8.

9. 10.

11.

12.

13.

14.

13.6 Scabicides and Pediculicides Diagnostic Agents 14.1 Ophthalmic Medicines 14.2 Radiocontrast Media Disinfectants and Antiseptics 15.1 Antiseptics 15.2 Disinfectants Diuretics Gastrointestinal Medicines 17.1 Antacids and other Antiulcer Medicines 17.2 Antiemetics 17.3 Antihaemorrhoidal Medicines 17.4 Antiinflammatory Medicines 17.5 Antispasmodic Medicines 17.6 Laxatives 17.7 Medicines used in Diarrhoea 17.7.1 Oral Rhydration Salts 17.7.2 Antidiarrhoeal Medicines Hormones, other Endocrine Medicines and Contraceptives 18.1 Adrenal Hormones and Synthetic Substitutes 18.2 Androgens 18.3 Contraceptives 18.3.1 Hormonal Contraceptives 18.3.2 Intrauterine Devices 18.3.3 Barrier Methods 18.3.4 Non Hormonal Contraceptives 18.4 Estrogens 18.5 Antidiabetics and Hyperglycaemics 18.5.1 Insulins and Other Antidiabetic Agents 18.5.2 Hyperglycaemics 18.6 Ovulation Inducers 18.7 Progestogens 18.8 Thyroid and Antithyroid Medicines Immunologicals 19.1 Diagnostic Agents 19.2 Sera and Immunoglobulins 19.3 Vaccines 19.3.1 For Universal Immunisation 19.3.2 For Specific Group of Individuals Muscle Relaxants (peripherally acting) and Cholinesterase Inhibitors Ophthalmological Preparations 21.1 Antiinfective Agents 21.2 Antiinflammatory Agents 21.3 Local Anaesthetics 21.4 Miotics and Antiglaucoma Medicines

19 19 19 20 20 20 21 21 21 21 22 22 22 22 22 23 23 23 23 23 23 23 23 24 24 24 24 24 24 24 24 24 25 25 25 25 25 25 26 26 26 26 27 27 27

15.

16. 17.

18.

19.

20. 21.

21.5 Mydriatics 21.6 Ophthalmic Surgical Aids 22. Oxytocics and Antioxytocics 22.1 Oxytocics 22.2 Antioxytocics Peritoneal Dialysis Solution Psychotherapeutic Medicines 24.1 Medicines used in Psychotic Disorders 24.2 Medicines used in Mood Disorders 24.2.1 Medicines used in Depressive Disorders 24.2.2 Medicines used in Bipolar Disorders 24.3 Medicines used for Generalized Anxiety and Sleep Disorders 24.4 Medicines used for Obsessive Compulsive Disorders and Panic Attacks Medicines Acting on the Respiratory Tract 25.1 Antiasthmatic Medicines 25.2 Antitussives Solutions correcting Water, Electrolyte, and Acid-Base Disturbances 26.1 Oral 26.2 Parenteral 26.3 Miscellaneous Vitamins and Minerals

27 27 27 27 27 28 28 28 28 28 28 28 29 29 29 29 29 29 30 30 30 31

23. 24.

25.

26.

27. Index

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

List of Participants in the preparation of National List of Essential Medicines
(i) (ii) (iii) (iv) (v) (vi) (vii) (viii) (ix) (x) (xi) (xii) (xiii) (xiv) (xv) Dr. S. D. Seth, Mr. Ashwini Kumar, Dr. Y. K. Gupta, Prof. of Pharmacology, AIIMS Dr. C. P. Singh, M. S., RML Hospital Dr. Y. N. Rao, DDG(M) Dr. Sandeep Guleria, AIIMS Dr. P. L. Joshi, Addl. Project Director, NACO Chairman Member Secretary Member Member Member Member Member

Dr. G. P. Sinha, Prof. of Medicine, Patna Medical College Member Dr. J. N. Pandey, HOD (Medicine), AIIMS Dr. G. K. Biswas, Addl. DG (Stores) Dr. Nikita Gupta Kamal Dr. Rita Sood (co-opted) Dr. R.N. Salhan (co-opted in April 2003) Dr. Usha Gupta (co-opted in December 2002) Mr. Brijesh Regal, WHO Consultant in DCG(I) office Member Member Member Member Member Member Coordinator

i

Preface to National List of Essential Medicines 2003
The review of National Essential Drugs List 1996, was due in the context of contemporary knowledge of the therapeutic products. An expert core committee was constituted by the Director General of Health Services in June 2002 for this purpose. The committee comprised of the following members: 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. Dr. Y. K. Gupta, Prof. of Pharmacology, AIIMS, New Delhi Dr. C. P. Singh, Medical Suprintendant, RML Hospital, New Delhi Dr. Y. N. Rao, DDG(M), DteGHS, MOHFW, New Delhi Dr. Sandeep Guleria, AIIMS, New Delhi Representative from ICMR, New Delhi Representative from NACO, New Delhi Dr. G. P. Sinha, Prof. of Medicines, Patna Medical College, Patna Dr. J. N. Pandey, HOD (Medicines), AIIMS, New Delhi Dr. G. K. Biswas, Addl. DG (Stores), DteGHS, MOHFW, New Delhi Dr. Nikita Gupta Kamal, Ophthalmologist Mr. Brijesh Regal, WHO Consultant in DCG(I) office Mr. Ashwini Kumar, DCG(I), DteGHS, MOHFW, New Delhi

Dr. S. D. Seth, Chair in Clinical Pharmacology, ICMR represented ICMR on the committee and was nominated by members to be the Chairman of the core committee. Dr. J. N. Pandey nominated Dr. Rita Sood, Addl. Prof. of Medicine, AIIMS to participate in the committee's delibrations. Dr. R. N. Salhan, Medical Suprintendant, RML Hospital contributed as member of the core committee, consequent to the retirement of Dr. C. P. Singh. Dr. P. L. Joshi was nominated by NACO as member of the committee. Dr. Usha Gupta, HOD Pharmacology, MAMC was coopted as member of the committee. After detailed delibrations in its first meeting, the committee agreed on the following criteria for identifying medicines for inclusion in the revised list: • • • • • Consideration of relevant disease burden in the country Information on the efficacy, safety and comparative cost effectiveness of the products Preference for single active compounds Cost effectiveness in the context of cost of treatment Available health delivery infrastructure (e.g. treatment facilities, training and experience of the available personnel; availability, financial resources; and environmental factors etc.)

Addition of drugs required in emergency care/life threatening situations were also considered. The committee also decided to follow the principles and concepts of “Essential” drugs as enunciated by WHO, as was done for the 1996 list. Accordingly, the description of the list as 'Essential Medicines' List was adopted and includes three components: a definition, a description of the selection criteria and a description of the ii

purpose for which such a list is developed, as follows: Definition: Essential medicines are those that satisfy the priority health care needs of the population. Selection criteria: Essential medicines are selected with due regard to disease prevalence, evidence on efficacy and safety, and comparative cost-effectiveness. Purpose: Essential medicines are intended to be available within the context of functioning health systems at all times in adequate amounts, in the appropriate dosage forms, with assured quality. Evidently, the word “Essential” does not purport to convey that number of other drugs available in the market are non-essential. Several sub-committees of clinicians were formed to review the various sub-groups of medicines and core committee members coordinated the proceedings of one or more of these respective sub groups. Each of these sub-group members, and indeed all those who provided their professional inputs, were clearly explained about the fundamental doctorine of the “essential” medicine's description as stated above. The medicines that have finally been included in this list have gone through several intensive screenings by the expert group as well as by invited and consulted professionals. Cost of therapy was worked out especially in the context of already available therapies and keeping in view the drugs available for these categories in the WHO list of essential medicines. Essential Drugs List of various states and WHO Model Formulary (2002) were also referred during the review process. Medicines used by various national programmes and emergency care drugs etc. which were earlier identified by health care professionals in the context of drug policy, were also considered. A new section on medicines for HIV-AIDS has been included since it was non-existent in the 1996 list. Several new anti-cancer drugs have been added in the current list. Additional drugs find place in the revised list. The committee is of the opinion that since the word 'drug' is now globally considered to have a different (narcotic) connotation, it may be replaced with the word 'Medicine' a term which is now more widely used to describe therapeutic pharmaceutical substances. WHO has also renamed its list as Model List of Essential “Medicines”. Accordingly, the present list has been titled “National List of Essential Medicines”. The committee gratefully acknowledges the contributions made by the following experts: Dr. M. P. Sharma, Dr. Praveen Aggarwal, Dr. Nikhil Tandon, Dr. P. P. Kotwal, Dr. Arvind Kumar, Dr. Sunesh Kumar, Dr. Rakesh Yadav, Dr. S. K. Maulik, Dr. S. C. Tiwari, Dr. Ravi Saksena, Dr. Renu Saxena, Dr. Kaushal K. Verma. Categories of the medicines as classified in NEDL 1996 have been revised to harmonize with the latest “Sections” used by WHO Essential Medicines List. Although WHO has published two separate lists in its latest revision (core list and complementary

iii

list) the committee has taken a conscious decision to keep the core and complementary medicines together in the main list itself. The complementary medicines have been marked * and denote those medicines which may be needed when other medicines listed in the category are not readily available or they may be required in specific situations or locations for well founded reasons. The committee observed that critical care or emergency care medicines are many times perceived as “life saving drugs” though this is not a standard terminology in the context of overall use of medicinal products. It would be seen that the essential medicines list consists of medicines meant for the management of a wide variety of conditions ranging from symptomatic relief, public health care, management of infections as well as for “life threatening” - emergency situations & for critical care. An index of therapeutic categories has been included in the final version for ease of reference. The nomenclature of medicines has been made consistent with that used in India [e.g. Epinephrine has been changed to Adrenaline and first letters of names of the medicines have been made capital, as in Indian Pharmacopoeia (I.P.)]. It is felt that this list may be reviewed every two years to keep it relevant in the context of contemporary knowledge and drugs that keep appearing on the horizon. The committee gratefully acknowledges the support provided by WHO-India Country Office for the review process as well as for dissemination of this list.

iv

Preface to National Essential Drugs List 1996

1.

The Ministry of Health, Government of India, is pleased to introduce the National Essential Drugs List for adoption in the country. The list is modelled on the WHO Essential Drugs List, and follows the general principles enunciated by WHO in the preparation of such lists. In India, healthcare is provided by both Private and Public Sectors. It is the responsibility of the Public Sector to establish healthcare institutions accessible to all sections of the population in all parts of the country, to provide diagnostic and treatment facilities. However, the state has not accepted the responsibility of supplying the entire requirement of drugs to treat all the patients receiving treatment in state-funded institutions. At the levels of Central and State Governments, medicines are supplied free of cost or against token payment to the government employees, and free of cost to the weaker section of the population who avail of the treatment facilities provided by the Government through primary, secondary or tertiary levels of state healthcare institutions. Through different National Programmes for the control of diseases of high morbidity and endemicity drugs are also supplied to effect a cure to all patients who approach the treatment centres established under such programmes. The National Essential Drugs List implies that the drugs included in it are adequate to meet the common contemporary health needs of the general population of the country and general obligation of the health administrators to ensure abundant availability of such drugs in the country. The drugs included in this list are generally safe and effective, and are approved by the Drugs Controller General, India, and are currently available at affordable prices to the general public. The exclusion in the National List of any drug which is currently available and recommended by the physicians does not imply that they are less effective or unsuitable to the Indian patients. Their exclusion may have been influenced by one or more of the following factors-cost benefit ratio, dependence on imports or imported raw materials, indicated in the treatment of diseases not considered significant in the National context, insufficient experience with the drug in India, not approved for use in the specific indication by the Drugs Controller General, India, or for which no standard is approved under the Drugs & Cosmetics Act and Rules. The safety, efficacy and quality of the drugs currently available in India are according to the standards prescribed in India and the exclusion of any drug from this list does not mean that it is less effective in comparison to any alternative drug which has found its place in the list. The national list is not intended as an imposition on the rights of state governments, government institutions, or private health care providers. It is meant to be used as a guideline to the concept of rational therapeutics and as an indicator of availability in the country. While the drugs selected are considered adequate to treat diseases common to most parts of the country, it is appreciated that specific regional requirements for drugs to treat diseases of local importance v

2.

3.

4.

5.

may not be available in the National List, and in such instances it will be appropriate for the state health administration (adopting the National List) to include drugs as may be considered adequate to treat these diseases. 6. A committee of experts was constituted by the DGHS in February, 1996, to prepare the National Essential Drugs List. This committee selected a core group comprising of: Dr. P. Das Gupta Dr. S. D. Seth Dr. C. B. Sridhar Dr. M. R. Samuel Dr. J. N. Mohanty Dr. G. K. Biswas Dr. J. S. Bapna to prepare a preliminary list. The core group took note of the procurement of State Governments, different Central Government institutions (e.g. CGHS, ESIC, GMSD, etc.) and WHO Essential Drugs List. The tentative list was subjected to scrutiny for therapeutic efficacy, availability and cost-effectiveness by the core group in consultation with experts in different disciplines of medicine. The draft was finally adopted in the meeting of experts held on 4th April, 1996. 7. The list is intended to be a dynamic document, subject to change, with addition and/or deletions, as medical knowledge advances and new drugs become available at remunerative pricing. The list uses generic names for scientific clarity. For convenience and ease of comparison, the same category numbers and headings have been used as in the WHO Model List (1995). However, only the names of the active bases have been used, avoiding the mention of salts or esters, e.g. morphine instead of morphine sulphate. The quantity mentioned in the strength of the dosage forms refers to the base unless by established practice or by pharmacopoeial standard it refers to the salt or the ester. The quality control standards are as in Indian Pharmacopoeia unless the drug is not included in I.P. Drugs marked with an asterisk (*) are to be considered as complementary drugs, i.e. those that are used if the other drugs in the category are not available or they are required for specific patients, situations or locations for valid reasons. The names of drugs are followed by the following letters to indicate their need at various levels of medical care: P S T U 11. Primary health care Secondary health care Tertiary health care Universal

8.

9.

10.

Although the drugs are listed by therapeutic categories, these are not necessarily meant to be used as prescribing guidelines. A drug that may deserve to be

vi

included in a particular category may not be found in the category as it may already be included in another category.

Acknowledgement
Our acknowledgements are due to Dr. Annapurna Rao, Dr. Ranjit Ray Chowdhury, Mr. Adeep Bagati, Dr. M. R. Samuel, Dr. S. D. Seth and Dr. J. S. Bapna for their valuable assistance and time to enable this first National Essential Drugs List to come out in such a short time. We are grateful to SEARO, WHO for their guidance and financial help for printing this list.

Dr. P. Das Gupta Member-Secretary Expert Committee New Delhi April 22, 1996

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2003

A list of items not included in the 1996 edition but added in this edition is given below:
Sl. No. 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. 34. 35. Name of the Drug Adenosine Alpha Interferon Alprazolam Artesunate Azithromycin Betaxolol Hydrochloride Bretylium Tosylate Bromocriptine Mesylate Calcium Gluconate Cefotaxime Ceftadizidime Ceftriaxone Cefuroxime Clarithromycin Clomiphene Citrate Clonidine Hydrochloride Clotrimazole Colchicine Cryoprecipitate Dexchlorpheniramine Maleate Didanosine Doxapram Efavirenz Esmolol Fluconazole Flumazenil Flucytosine Flutamide Fresh Frozen Plasma Gemcitabine Hydrochloride Glucagon Hormone Releasing IUD Indinavir Lamivudine + Nevirapine + Stavudine Lamivudine + Zidovudine Category 12.2 8.2 24.3 6.5.3.1 6.2.2 21.4 12.2 9.0 4.2 6.2.1 6.2.1 6.2.1 6.2.1 6.2.2 18.6 12.3 6.3 2.3 11.2 3 6.4.2.1 1.4 6.4.2.2 12.2 6.3 4.2 6.3 8.2 11.1 8.2 18.5.2 18.3.1 6.4.2.3 6.4.2.1 6.4.2.1

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Sl. No. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. 61. 62. 63. 64. 65. 66. 67. 68. 69 70. 71.

Name of the Drug Lamivudine Losartan Potassium Magnesium Sulphate Medroxy Progesterone Acetate Methyl Cellulose Metoprolol Midazolam Mifepristone N/2 Saline N/5 Saline Nelfinavir Nevirapine Nitrazepam Odansetron Ofloxacin Omeprazole Paclitaxel Physostigmine Salicylate Platelet Rich Plasma Potassium Chloride Pyridostigmine Bromide Pyrimethamine Raloxifene Ritonavir Roxithromycin Saquinavir Sodium Bicarbonate Stavudine Sulphadiazine Terazosin Thiacetazone + Isoniazid Trifluoperazine Trimethoprim Vancomycin Hydrochloride Zidovudine Zinc Oxide

Category 6.4.2.1 12.3 5 18.7 12.1 1.3 22.1 26.2 26.2 6.4.2.3 6.4.2.2 24.3 8.4 6.2.4 17.1 8.2 21.4 11.2 26.2 20 6.5.3.1 8.3 6.4.2.3 6.2.2 6.4.2.3 26.2 6.4.2.1 6.2.2 12.3 6.2.4 24.1 6.5.4 6.2.2 6.4.2.1 13.4

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A list of items included in the 1996 edition but not included in this edition is given below:
Sl. No. 1. 2. 3. Name of the Drug Biperiden Ethnylestradiol + Norgestrel Neomycin Category 9 18.3 6.2.2

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List of drug movements across categories
Sl. No. 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. Name of the Drug From Acetyl Salicylic Acid Acyclovir Allopurinol Amitriptyline B.C.G Vaccine Centchroman D.P.T Vaccine Diloxanide Furoate Dobutamine Dopamine Ethinylestradiol + Levonorgestrel Ethinylestradiol + Norethisterone Fluoxetine Furazolidone Hepatitis B Vaccine Imipramine IUD Containing Copper Loperamide Measles Vaccine Metronidazole Oral Poliomyelitis Vaccine Oral Rehydration Salts Pentamidine Praziquantel Rabies Vaccine Sodium Stibogluconate Streptokinase Sulphadoxine + Pyrimethamine Tetanus Toxoid Tinidazole Urokinase 12.6 6.5 2.1 24.2 19.3 18.3 19.3 6.4.1 12.5 12.5 18.3 18.3 24.2 17.7 19.3 24.2 18.3 17.7 19.3 6.4.1 19.3 17.7 6.4.2 6.1.1 19.3 6.4.2 12.6 6.4.3 19.3 6.4.1 12.6 Category To 12.5 6.4.1 2.3 24.2.1 19.3.1 18.3.4 19.3.1 6.5.1 12.4 12.4 18.3.1 18.3.1 24.2.2 17.7.2 19.3.1 24.2.1 18.3.2 17.7.2 19.3.1 6.5.1 19.3.1 17.7.1 6.5.2 6.1.3 19.3.2 6.5.2 12.5 6.5.3.2 19.3.2 6.5.1 12.5

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Therapeutic Categories
Sl. No. 1. 2. Therapeutic Category Anaesthetics Analgesics, Antipyretics, Nonsteroidal Antiinflammatory Medicines, Medicines used to treat Gout and Disease Modifying Agents used in Rheumatoid Disorders. Antiallergics and Medicines used in Anaphylaxis Antidotes and Other Substances used in Poisonings Anticonvulsants/Antiepileptics Antiinfective Medicines Antimigraine Medicines Antineoplastic, Immunosuppressives and Medicines used in Palliative Care Antiparkinsonism Medicines Medicines affecting the Blood Blood Products and Plasma Substitutes Cardiovascular Medicines Dermatological Medicines (Topical) Diagnostic Agents Disinfectants and Antiseptics Diuretics Gastrointestinal Medicines Hormones, other Endocrine Medicines and Contraceptives Immunologicals Muscle Relaxants (peripherally acting) and Cholinesterase Inhibitors Page No. 1 2

3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20.

3 3 4 5 11 12 14 14 15 16 18 19 20 21 21 23 25 26

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Sl. No. 21. 22. 23. 24. 25. 26. 27.

Therapeutic Category Ophthalmological Preparations Oxytocics and Antioxytocics Peritoneal Dialysis Solution Psychotherapeutic Medicines Medicines Acting on the Respiratory Tract Solutions correcting Water, Electrolyte, and Acid-Base Disturbances Vitamins and Minerals

Page No. 26 27 28 28 29 29 30

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Medicine

Category

Route of Administration/ Dosage Form

Strengths

1.
1.1

Anaesthetics
General Anaesthetics and Oxygen Ether, Anaesthetic Halothane Isoflurane* Ketamine Hydrochloride Nitrous Oxide Oxygen S, T S, T S, T U U U Inhalation Inhalation Inhalation Injection Inhalation Inhalation Injection 0.5 g, 1 g powder 10 mg / ml 50 mg / ml

Thiopentone Sodium S, T 1.2 Local Anaesthetics Bupivacaine Hydrochloride S, T

Injection

0.25%, 0.5% 0.5% + 7.5% Glucose 1% 2-5% 1-2% 5% + 7.5% Glucose 1%, 2% + Adrenaline 1:200,000 In vial

Ethyl Chloride Lignocaine Hydrochloride

U U

Spray Topical Forms Injection Spinal Injection

Lignocaine Hydrochloride + Adrenaline 1.3

U

Preoperative Medication and Sedation for Short Term Procedures Atropine Sulphate Diazepam U U Injection Tablets Injection 0.6 mg / ml 5 mg 5 mg / ml

* Complementary

1

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine Midazolam

Category U

Route of Administration/ Dosage Form Injection Injection Syrup

Strengths 1 mg / ml 5 mg / ml 10 mg / ml 5 mg / 5 ml

Morphine Sulphate S, T Promethazine 1.4 U

Postoperative Respiratory Stimulant Doxapram* T Injection 4 mg / ml

2.

Analgesics, Antipyretics, Nonsteroidal Antiinflammatory Medicines, Medicines used to treat Gout and Disease Modifying Agents used in Rheumatoid Disorders.
Non-Opioid Analgesics, Antipyretics and Nonsteroidal Antiinflammatory Medicines Acetyl Salicylic Acid U Diclofenac T Tablets Tablets Injection Ibuprofen Paracetamol U U Tablets Injection Syrup Tablets 300 - 350 mg 50 mg, 100 mg 25 mg / ml 200 mg, 400 mg 150 mg / ml 125 mg / 5ml 500 mg

2.1

2.2

Opioid Analgesics Morphine Sulphate Pentazocine Pethidine Hydrochloride S, T S, T S, T Injection Tablets Tablets Injection Injection 10 mg / ml 10 mg 25 mg, 30 mg / ml 50 mg / ml

2.3

Medicines used to treat Gout Allopurinol Colchicine S, T S, T Tablets Tablets 100 mg 0.5 mg * Complementary

2

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine 2.4

Category

Route of Administration/ Dosage Form

Strengths

Disease Modifying Agents used in Rheumatoid Disorders Azathioprine Chloroquine Phosphate Methotrexate Sulfasalazine S, T S, T S, T S, T Tablets Tablets Tablets Tablets 50 mg 150 mg 2.5 mg 500 mg

3.

Antiallergics and Medicines used in Anaphylaxis
Adrenaline Bitartrate Chlorpheniramine Maleate U U Injection Tablets Syrup Tablets Injection Injection Injection Tablets Tablets Syrup 1 mg / ml 4 mg 0.5 mg / 5 ml 0.5 mg 4 mg / ml 100 mg 22.75 mg / ml 5 mg 10 mg, 25 mg 5 mg / 5 ml

Dexchlorpheniramine Maleate Dexamethasone Hydrocortisone Sodium Succinate Pheniramine Maleate Prednisolone Promethazine U

U U S U

4.
4.1

Antidotes and Other Substances used in Poisonings
Nonspecific Activated Charcoal U Atropine Sulphate U Powder Injection 0.6 mg / ml

3

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine 4.2 Specific Antisnake Venom

Category

Route of Administration/ Dosage Form

Strengths

U

Injection Polyvalent Solution/ Lyophilyzed Polyvalent Serum Injection Injection Injection in oil Injection Injection 100 mg / ml 500 mg 50 mg / ml 0.1 mg / ml 10 mg / ml

Calcium Gluconate S,T Desferrioxamine Mesylate Dimercaprol Flumazenil* Methylthioninium Chloride (Methylene blue) Naloxone Penicillamine Pralidoxime Chloride (2-PAM) Sodium Nitrite Sodium Thiosulphate S, T S, T T S, T

S, T S, T S, T S, T S, T

Injection Tablets or Capsules Injection Injection Injection

0.4 mg / ml 250 mg 25 mg / ml 30 mg / ml 250 mg/ ml

5.

Anticonvulsants/Antiepileptics
Carbamazepine U Tablets Syrup Diazepam Magnesium Sulphate Phenobarbitone U T U ST Phenytoin Sodium U Injection Injection Tablets Injection Capsules or Tablets Syrup Injection 100 mg, 200 mg 20 mg / ml 5 mg / ml 500 mg /ml 30 mg, 60 mg 200 mg / ml 50 mg, 100 mg 25 mg / ml 50 mg / ml * Complementary

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2003

Medicine Sodium Valproate

Category U

Route of Administration/ Dosage Form Tablets Syrup

Strengths 200 mg, 500 mg 200 mg / 5 ml

6.
6.1

Antiinfective Medicines
Anthelminthics

6.1.1 Intestinal Anthelminthics Albendazole Mebendazole Niclosamide Pyrantel Pamoate 6.1.2 Antifilarials Diethylcarbamazine U Citrate Tablets 50 mg U U U U Tablets Suspension Tablets Suspension Chewable Tablets Tablets Suspension 400 mg 200 mg/ 5 ml 100 mg 100 mg / 5 ml 500 mg 250 mg 250 mg / 5 ml

6.1.3 Antischistosomals and Antitrematode Medicines Praziquantel 6.2 Antibacterials S, T Tablets 600 mg

6.2.1 Beta Lactam Medicines Amoxicillin U Powder for suspension Capsules Capsules Powder for suspension Injection Benzathine Benzylpenicillin U Injection 125 mg / 5 ml 250 mg 500 mg 250 mg, 500 mg 125 mg / 5 ml 500 mg 6 lacs, 12 lacs, 24 lacs units

Ampicillin

U

5

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine

Category

Route of Administration/ Dosage Form Injection Injection

Strengths

Benzylpenicillin Cefotaxime*

U S, T

5 lacs, 10 lacs units 125 mg, 250 mg, 500 mg 250mg, 1g 250 mg, 1 g 250 mg, 750 mg 250 mg, 500 mg 250 mg 125 mg / 5 ml Crystalline penicillin (1 lac units) + Procaine penicillin (3 lacs units)

Ceftazidime* Ceftriaxone* Cefuroxime* Cloxacillin

S, T S, T S, T U

Injection Injection Injection Capsules Injection Liquid

Procaine Benzylpenicillin

U

Injection

6.2.2 Other Antibacterials Amikacin* Azithromycin* S, T S, T Injection Capsules or Tablets Suspension Injection Cephalexin* U Syrup Capsules Capsules Injection Suspension Capsules, Tablets Injection Tablets 250 mg / 2 ml 100 mg, 250 mg, 500 mg 100 mg / 5 ml 500 mg 125 mg / 5 ml 250 mg, 500 mg 500 mg 1g 125 mg / 5 ml 250 mg, 500 mg 200 mg / 100 ml 250 mg, 500 mg * Complementary

Clarithromycin* Chloramphenicol

S, T S, T S, T S, T U

Ciprofloxacin Hydrochloride

6

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine

Category

Route of Administration/ Dosage Form Tablets Suspension Capsules Syrup Tablets Injection Tablets Injection

Strengths

Co-Trimoxazole U (Trimethoprim + Sulphamethoxazole) Doxycycline Erythromycin Estolate Gentamicin Metronidazole U U

40 + 200 mg 80 + 400 mg 40 + 200 mg / 5 ml 100 mg 125 mg / 5 ml 250 mg, 500 mg. 10 mg / ml 40 mg / ml 200 mg, 400 mg 500 mg / 100 ml 250 mg, 500 mg 100 mg 400 mg 50 mg, 150 mg 500 mg 250 mg 500 mg, 1 g

U U

Nalidixic Acid Nitrofurantoin Norfloxacin Roxithromycin* Sulphadiazine* Tetracycline Vancomycin Hydrochloride*

U U U S, T S, T U T

Tablets Tablets Tablets Tablets Tablets Tablets or Capsules Injection

6.2.3 Antileprosy Medicines Clofazimine Dapsone Rifampicin S, T U U Capsules Tablets Capsules or Tablets 50 mg, 100 mg 50 mg, 100 mg 150 mg, 300 mg

* Complementary

7

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine

Category

Route of Administration/ Dosage Form

Strengths

6.2.4 Antituberculosis Medicines Ethambutol U Tablets 200 mg, 400 mg, 600 mg, 800 mg 50 mg, 100 mg, 300 mg 100 mg, 200 mg 50 mg / 5 ml 500 mg, 750 mg, 1000 mg, 1500 mg 50 mg, 150 mg, 300 mg, 450 mg 100 mg / 5 ml 0.75 g, 1 g 150 mg + 300 mg

Isoniazid

U

Tablets

Ofloxacin*

S, T

Tablets Syrup

Pyrazinamide

U

Tablets

Rifampicin

U

Capsules/Tablets

Syrup Streptomycin Sulphate Thiacetazone + Isoniazid 6.3 Antifungal Medicines Amphotericin B Clotrimazole S, T U Injection Pessaries Gel Fluconazole S, T Capsules or Tablets U S, T Injection Tablets

50 mg 100 mg 200 mg 2% 50 mg, 100 mg, 150 mg, 200 mg 250 mg 125 mg, 250 mg 200 mg * Complementary

Flucytosine Griseofulvin Ketoconazole

S, T U S, T

Capsules Capsules or Tablets Tablets

8

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine Nystatin 6.4 Antiviral Medicines

Category U

Route of Administration/ Dosage Form Tablets Pessaries

Strengths 500,000 IU 100,000 IU

6.4.1 Antiherpes Medicines Acyclovir* S, T Tablets Injection Suspension 6.4.2 Antiretroviral Medicines* 6.4.2.1 Nucleoside Reverse Transcriptase Inhibitors Didanosine* Lamivudine* Lamivudine + Nevirapine + Stavudine* Lamivudine + Zidovudine* S, T S, T Tablets Tablets 250 mg 400 mg 150 mg 200 mg, 400 mg 250 mg, 500 mg 400 mg / 5 ml

S, T

Tablets

150 mg + 200 mg + 30 mg 150 mg + 300 mg 15 mg, 30 mg, 40 mg 100 mg 300 mg

S, T

Tablets

Stavudine*

S, T

Capsules

Zidovudine*

S, T

Tablets

6.4.2.2 Non-nucleoside Reverse Transcriptase Inhibitors Efavirenz* Nevirapine* 6.4.2.3 Protease Inhibitors Indinavir* Nelfinavir* * Complementary S, T S, T Capsules Capsules 200 mg, 400 mg 250 mg S, T S, T Capsules Capsules Suspension 200 mg 600 mg 200 mg 50 mg / 5 ml

9

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine

Category

Route of Administration/ Dosage Form Capsules Syrup Capsules

Strengths

Ritonavir* Saquinavir* 6.5

S, T S, T

100 mg 400 mg / ml 200 mg

Antiprotozoal Medicines

6.5.1 Antiamoebic and Antigiardiasis Medicines Diloxanide Furoate U Metronidazole U Tablets Tablets Injection Tinidazole U Tablets 500 mg 200 mg, 400 mg 500 mg / 100 ml 500 mg

6.5.2 Antileishmaniasis Medicines Amphotericin B Pentamidine Isothionate Sodium Stibogluconate S, T S, T Injection Injection 50 mg 200 mg

S, T

Injection

100 mg / ml

6.5.3 Antimalarial Medicines 6.5.3.1 For Curative Treatment Artesunate Chloroquine Phosphate T U Injection Tablets Injection Syrup Primaquine Pyrimethamine Quinine Sulphate Sulfadoxine + Pyrimethamine U U U S, T U Tablets Tablets Tablets Injection Tablets 60 mg 150 mg base 40 mg / ml 50 mg / 5 ml 2.5 mg, 7.5 mg 25 mg 300 mg 300 mg / ml 500 mg + 25 mg * Complementary

10

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine

Category

Route of Administration/ Dosage Form

Strengths

6.5.3.2 For Prophylaxis Chloroquine Phosphate U Tablets Syrup 6.5.4 Antipneumocystosis and Antitoxoplasmosis Medicines Co-Trimoxazole U (Trimethoprim + Sulphamethoxazole) Tablets Suspension 40 + 200 mg 80 + 400 mg 40 + 200 mg / 5 ml 200 mg 150 mg base 50 mg / 5 ml

Pentamidine Isothionate Trimethoprim

S, T

Injection

U

Tablets

100 mg

7.
7.1

Antimigraine Medicines
For Treatment of Acute Attack Acetyl Salicylic Acid U Dihydroergotamine S, T Paracetamol U Tablets Tablets Tablets 300 - 350 mg 1 mg 500 mg

7.2

For Prophylaxis Propranolol Hydrochloride U Tablets 10 mg, 40 mg

11

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine

Category

Route of Administration/ Dosage Form

Strengths

8.
8.1

Antineoplastic, Immunosuppressives and Medicines used in Palliative Care
Immunosuppressive Medicines Azathioprine* Cyclosporine T T Tablets Capsules 50 mg 10 mg, 25 mg, 50 mg, 100 mg 100 mg / ml

Concentrate for Injection 8.2 Cytotoxic Medicines Actinomycin D* Alpha Interferon* Bleomycin* Busulphan* Cisplatin* T T T T T Injection Injection Injection Tablets Injection Tablets Injection

0.5 mg 3 million IU 15 mg 2 mg 10 mg / vial 50 mg / vial 50 mg 200 mg 500 mg 100 mg / vial 500 mg / vial 1000 mg / vial 50 mg, 100 mg 10 mg 50 mg 100 mg 100 mg / 5 ml * Complementary

Cyclophosphamide* T

Cytosine Arabinoside*

T

Injection

Danazol* Doxorubicin* Etoposide*

T T T

Capsules Injection Capsules Injection

12

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine

Category

Route of Administration/ Dosage Form Tablet Injection Injection Injection Injection Tablets Tablets Injection Tablets Injection Injection Injection Capules Injection Injection

Strengths

Flutamide* 5-Fluorouracil* Folinic Acid* Gemcitabine Hydrochloride* L- Asparaginase* Melphalan* Mercaptopurine* Methotrexate* Mitomycin-C* Paclitaxel* Procarbazine* Vinblastine Sulphate* Vincristine 8.3

T T T T T T T T T T T T T

250 mg 250 mg / 5 ml 3 mg / ml 200 mg 1g 10000 KU 2 mg, 5 mg 50 mg, 100 mg / ml 2.5 mg 50 mg / ml 10 mg 30 mg / 5 ml 50 mg 10 mg 1 mg / ml

Hormones and Antihormones Prednisolone* S, T Tablets Injection 5 mg 20 mg 25 mg (as sodium phosphate or succinate) 60 mg 10 mg, 20 mg

Raloxifene* Tamoxifen Citrate*

T T

Tablets Tablets

* Complementary

13

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine

Category

Route of Administration/ Dosage Form

Strengths

8.4

Medicines used in Palliative Care Morphine Sulphate* T Ondansetron* S, T Tablets Tablets Injection Syrup 10 mg 4 mg, 8 mg 2 mg / ml 2 mg / 5 ml

9.

Antiparkinsonism Medicines
Bromocriptine Mesylate Levodopa+ Carbidopa S, T Tablets 1.25 mg, 2.5 mg 100 mg + 10 mg 250 mg + 25 mg 100 mg + 25 mg 2 mg

U

Tablets

Trihexyphenidyl Hydrochloride

U

Tablets

10. Medicines affecting the Blood
10.1 Antianemia Medicines Cyanocobalamin Ferrous Salt U U Injection Tablets 1 mg / ml Equivalent to 60 mg elemental iron 25 mg elemental iron (as sulphate) / ml 1 mg, 5 mg 50 mg iron/ ml 5 mg * Complementary

Oral solution

Folic Acid Iron Dextran Pyridoxine

U S, T U

Tablets Injection Tablets

14

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine

Category

Route of Administration/ Dosage Form

Strengths

10.2

Medicines Affecting Coagulation Acenocoumarol* Heparin Sodium Menadione Sodium Sulphite S, T S, T Tablets Injection 1 mg, 2 mg, 4 mg 1000 IU / ml 5000 IU / ml 10 mg 10 mg / ml 10 mg / ml 5 mg

S, T

Tablets Injection Injection Tablets

Protamine Sulphate S, T Phytomenadione Warfarin Sodium S, T S, T

11.
11.1

Blood Products and Plasma Substitutes
Plasma Substitutes Dextran-40 Dextran-70 Fresh Frozen Plasma* U U T Injection Injection Injection Injection Injection 6% 3.5% 10% 6%

Hydroxyethyl Starch S, T (Hetastarch) Polygeline 11.2 S, T

Plasma Fractions for Specific Use Albumin Cryoprecipitate Factor VIII Concentrate* S, T S, T S, T Injection Injection Injection Dried 5%, 20%

Factor IX Complex (Coagulation Factors II,VII, IX, X)* S, T * Complementary

Injection

Dried

15

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine

Category

Route of Administration/ Dosage Form Injection

Strengths

Platelet Rich Plasma S, T

12. Cardiovascular Medicines
12.1 Antianginal Medicines Acetyl Salicylic Acid* U Tablets 75 mg, 100 mg 350 mg 30 mg, 60 mg 0.5 mg 5 mg / ml 10 mg, 20 mg 25 mg, 50 mg 1 mg/ ml 10 mg, 40 mg 1 mg / ml

Diltiazem Glyceryl Trinitrate

S, T U

Tablets Sublingual Tablets Injection Tablets Tablets Injection Tablets Injection

Isosorbide 5 Mononitrate/DinitrateU Metoprolol* Propranolol 12.2 U U

Antiarrhythmic Medicines Adenosine* Amiodarone S, T S, T Injection Tablets Injection Bretylium Tosylate* T Diltiazem Diltiazem* Esmolol* Isoprenaline Hydrochloride* Lignocaine Hydrochloride Mexiletine Hydrochloride Procainamide Hydrochloride S, T T T T S, T S, T Injection Tablets Injection Injection Injection Injection Capsules, Injection T Tablets Injection 3mg / ml 100 mg, 200 mg 150 mg 1 mg, 2 mg 4 mg / ml 30 mg, 60 mg 5 mg/ ml 10 mg / ml 2 mg / ml 1%, 2% 50 mg, 150 mg 25 mg / ml 250 mg 100 mg / ml * Complementary

16

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine

Category

Route of Administration/ Dosage Form Tablets Tablets Injection

Strengths

Quinidine Verapamil 12.3

T S, T

100 mg 40 mg, 80 mg 2.5 mg / ml

Antihypertensive Medicines Amlodipine Atenolol Chlorthalidone* Clonidine Hydrochloride* Enalapril Maleate U U U S, T Tablets Tablets Tablets Tablets 2.5 mg, 5 mg, 10 mg 50 mg 100 mg 25 mg, 50 mg 100 mg 150 mg 2.5 mg, 5 mg, 10 mg 1.25 mg / ml 25 mg, 50 mg 250 mg

U

Tablets Injection

Losartan Potassium* Methyldopa Nifedipine

S, T U S, T

Tablets Tablets Capsules

5 mg, 10 mg Tablets 10 mg, 20 mg, Sustained release capsules 10 mg, or tablets 20 mg, Tablets 10 mg, 40 mg 50 mg/ 5 ml 1 mg, 2 mg, 5 mg

Propranolol Sodium Nitroprusside* Terazosin*

U

T S, T

Injection Tablets

* Complementary

17

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine

Category

Route of Administration/ Dosage Form

Strengths

12.4

Medicines used in Heart Failure Digoxin S, T Tablets Injection Elixir Injection Injection 0.25 mg 0.25 mg / ml 0.05 mg / ml 50 mg / ml 40 mg / ml

Dobutamine* Dopamine Hydrochloride 12.5

S, T S,T

Antithrombotic Medicines Acetyl Salicylic Acid U Heparin Sodium* Streptokinase* Urokinase* S, T S, T T Tablets Injection Injection Injection 75 mg, 100 mg 1000 IU / ml 5000 IU / ml 750,000 IU 15,00,000 IU 500,000 IU / ml 10,00,000 IU / ml

13. Dermatological Medicines (Topical)
13.1 Antifungal Medicines Benzoic Acid + Salicylic Acid Miconazole 13.2 U U Ointment or Cream Ointment or Cream 6% + 3% 2%

Antiinfective Medicines Acyclovir S, T Cream Cream 5% 0.5%

Framycetin Sulphate U Methylrosanilinium Chloride (Gentian Violet)

U

Aqueous solution

0.5%

18

* Complementary

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine

Category

Route of Administration/ Dosage Form

Strengths

Neomycin + Bacitracin Povidone Iodine Silver Nitrate Silver Sulphadiazine 13.3

U U U U

Ointment Solution or Ointment Lotion Cream

5 mg + 500 IU 5% 10% 1%

Antiinflammatory and Antipruritic Medicines Betamethasone Dipropionate Calamine U U Cream / Ointment Lotion 0.05%

13.4

Astringent Medicines Zinc Oxide U Dusting Powder

13.5

Medicines Affecting Skin Differentiation and Proliferation Coal Tar Dithranol* Glycerin Salicylic Acid U T U U Solution Ointment Solution Solution 5% 5% 0.1-2%

13.6

Scabicides and Pediculicides Benzyl Benzoate Gamma Benzene Hexachloride U Lotion 25%

U

Lotion

1%

14. Diagnostic Agents
14.1 Ophthalmic Medicines Fluorescein S, T Eye drops 1%

* Complementary

19

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine

Category

Route of Administration/ Dosage Form Eye Drops Eye drops

Strengths

Lignocaine Tropicamide 14.2 Radiocontrast Media Barium Sulphate Calcium Ipodate Iopanoic Acid Meglumine Iothalamate

S, T S, T

4% 1%

S, T S, T S, T S, T

Suspension Injection Tablets Injection

100% w/v 250% w/v 3g 500 mg 60% w/v (iodine = 280 mg / ml) 5-8 g iodine in 100-250 ml 500600 mg / ml 70% w/v (Iodine = 420 mg / ml) 60% w/v (Iodine conc. = 292 mg / ml) 76% w/v (Iodine conc. = 370 mg / ml)

Meglumine Iotroxate S, T

Solution

Propyliodone

S, T

Oily, suspension Injection

Sodium Iothalamate S, T

Sodium Meglumine Diatrizoate

S, T

Injection

15. Disinfectants and Antiseptics
15.1 Antiseptics Acriflavin+Glycerin U Solution Tincture

Benzoin Compound U

20

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine

Category

Route of Administration/ Dosage Form Solution Solution Solution Paint Solution Solution

Strengths

Cetrimide Chlorhexidine Ethyl Alcohol 70% Gentian Violet

U U U U

20% (conc. for dilution) 5% (conc. for dilution)

0.5%, 1% 6% 5%, 10%

Hydrogen Peroxide U Povidone Iodine 15.2 Disinfectants Bleaching Powder Formaldehyde IP Glutaraldehyde Potassium Permanganate U U S,T U U

Powder Solution Solution Crystals for solution 2%

16. Diuretics
Furosemide U Injection, Tablets Tablets Injection Tablets 10 mg/ ml, 40 mg 25 mg, 50 mg 10%, 20% 25 mg

Hydrochlorothiazide U Mannitol* Spironolactone U U

17. Gastrointestinal Medicines
17.1 Antacids and other Antiulcer Medicines Aluminium Hydroxide + Magnesium Hydroxide U Tablet Suspension

* Complementary

21

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine Omeprazole Ranitidine Hydrocholoride 17.2 Antiemetics Domperidone Metoclopramide

Category U U

Route of Administration/ Dosage Form Capsules Tablets Injection

Strengths 10 mg, 20 mg, 40 mg 150 mg, 300 mg 25 mg / ml

U U

Tablets Syrup Tablets Syrup Injection Tablets Tablets Elixir or Syrup Injection

10 mg 1 mg / ml 10 mg 5 mg / ml 5 mg / ml 5 mg, 25 mg 10 mg, 25 mg 5 mg / 5 ml 25 mg / ml

Prochlorperazine Promethazine

U U

17.3

Antihaemorrhoidal Medicines Local Anaesthetic, U Astringent and Antiinflammatory Medicines Ointment /suppository

17.4

Antiinflammatory Medicines Sulfasalazine T Tablets 500 mg

17.5

Antispasmodic Medicines Dicyclomine Hydrochloride Hyoscine Butyl Bromide U Tablets Injection Tablets or Injection 10 mg 10 mg / ml 10 mg 20 mg / ml

U

17.6

Laxatives Bisacodyl Isphaghula U U Tablets/ suppository Granules 5 mg

22

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine 17.7

Category

Route of Administration/ Dosage Form

Strengths

Medicines used in Diarrhoea U Powder for solution As per IP

17.7.1 Oral Rehydration Salts

17.7.2 Antidiarrhoeal Medicines Furazolidone Loperamide* (Contraindicated for paediatric use) S, T S, T Tablets Syrup Capsules 100 mg 25 mg / 5 ml 2 mg

18. H o r m o n e s , o t h e r E n d o c r i n e M e d i c i n e s a n d Contraceptives
18.1 Adrenal Hormones and Synthetic Substitutes Dexamethasone Hydrocortisone Sodium Succinate S, T U Tablets Injection Injection Injection Tablets 0.5 mg 4 mg / ml 100 mg / ml 40 mg/ ml 5 mg, 10 mg

Methylprednisolone S, T Prednisolone 18.2 Androgens Testosterone T T U

Capsules Injection

40 mg (as undecanoate) 25 mg / ml (as propionate)

18.3

Contraceptives

18.3.1 Hormonal Contraceptives Ethinylestradiol + Levonorgesterol Ethinylestradiol + Norethisterone U Tablets .03 mg + 0.15 mg 0.035 mg + 1.0 mg

U

Tablets

* Complementary

23

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine Hormone Releasing IUD

Category

Route of Administration/ Dosage Form

Strengths

T

Levonorgesterol Releasing IUD

18.3.2 Intrauterine Devices IUD containing Copper U 18.3.3 Barrier Methods Condoms U

18.3.4. Non Hormonal Contraceptives Centchroman 18.4 Estrogens Ethinylestradiol 18.5 U Tablets 0.01 mg, 0.05 mg U Tablets 30 mg

Antidiabetics and Hyperglycaemics

18.5.1 Insulins and Other Antidiabetic Agents Glibenclamide Insulin Injection (Soluble) U U Tablets Injection Injection 2.5 mg, 5 mg 40 IU / ml 40 IU / ml

Intermediate Acting U Insulin (Lente/NPH Insulin) Metformin 18.5.2 Hyperglycaemics Glucagon* 18.6 Ovulation Inducers Clomiphene Citrate* 18.7 Progestogens Medroxy Progesterone Acetate Norethisterone U T T U

Tablets

500 mg

Injection

1 mg / ml

Tablets

25 mg, 50 mg 100 mg

Tablets

5 mg, 10 mg

U

Tablets

5 mg * Complementary

24

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine

Category

Route of Administration/ Dosage Form

Strengths

18.8

Thyroid and Antithyroid Medicines Carbimazole Levothyroxine Iodine S, T S, T S, T Tablets Tablets Solution 5 mg, 10 mg 0.1 mg 8 mg / 5 ml

19. Immunologicals
19.1 Diagnostic Agents Tuberculin, Purified U Protein Derivative 19.2 Sera and Immunoglobulins Anti-D Immunoglobulin (Human) Antisnake Venom S, T Injection 250 mg, 300 mg Injection

U

Injection Injection Injection Injection

10 ml 250 IU, 500 IU 10,000 IU 150 IU / ml

Antitetanus Human U Immunoglobin Diphtheria Antitoxin S, T Rabies Immunoglobulin 19.3 Vaccines U

19.3.1 For Universal Immunisation B.C.G Vaccine D.P.T Vaccine U U Injection Injection Injection Injection

Hepatitis B Vaccine U Measles Vaccine U

25

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine Oral Poliomyelitis Vaccine (Live Attenuated)

Category U

Route of Administration/ Dosage Form Solution

Strengths

19.3.2 For Specific Group of Individuals Rabies Vaccine Tetanus Toxoid U U Injection Injection

20. Muscle Relaxants (peripherally acting) and Cholinesterase Inhibitors
Atracurium Besylate* Neostigmine Pancuronium Bromide Pyridostigmine Bromide Succinyl Choline Chloride S, T S, T S, T S, T S, T Injection Tablets Injection Injection Tablet Injection Injection 10 mg / ml 15 mg 0.5 mg/ ml 2 mg/ml 60 mg 1 mg / ml 50 mg/ ml

21. Ophthalmological Preparations
21.1 Antiinfective Agents Chloramphenicol Ciprofloxacin Hydrochloride Gentamicin Miconazole Povidone Iodine Sulphacetamide Sodium Tetracycline Hydrochloride U U U U S, T U U Drops/Ointment Drops/Ointment Drops Drops Drops Drops Ointment 0.4%, 1% 0.3% 0.3% 1% 0.6% 10%, 20%,30% 1%

26

* Complementary

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine 21.2

Category

Route of Administration/ Dosage Form

Strengths

Antiinflammatory Agents Prednisolone Acetate U Drops Drops Drops 0.1% 1% 0.05%, 0.1%

Prednisolone U Sodium Phosphate Xylometazoline 21.3 Local Anaesthetics Tetracaine Hydrochloride 21.4 U U

Drops

0.5%

Miotics and Antiglaucoma Medicines Acetazolamide Betaxolol Hydrochloride Physostigmine Salicylate* Pilocarpine Timolol Maleate S, T S, T S, T S, T S, T Tablets Drops Drops Drops Drops 250 mg 0.25%, 0.5% 0.25 % 2%, 4% 0.25%, 0.5%,

21.5

Mydriatics Atropine Sulphate Homatropine Phenylephrine U U U Drops/Ointment Drops Drops 1% 2% 5%

21.6

Ophthalmic Surgical Aids Methyl Cellulose* T Injection 2%

22. Oxytocics and Antioxytocics
22.1 Oxytocics Methyl Ergometrine U Mifepristone Oxytocin 22.2 Antioxytocics Isoxsuprine Hydrochloride * Complementary S, T Tablets Injection 10 mg 5 mg / ml T S, T Tablets Injection Tablets Injection 0.125 mg 0.2 mg / ml 200 mg 5 IU / ml, 10 IU / ml

27

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine Terbutaline Sulphate

Category S, T

Route of Administration/ Dosage Form Tablets Injection

Strengths 2.5 mg 0.5 mg / ml

23. Peritoneal Dialysis Solution
Intraperitoneal Dialysis Solution (of approximate composition)

24. Psychotherapeutic Medicines
24.1 Medicines used in Psychotic Disorders Chlorpromazine Hydrochloride U Tablets Syrup Injection Haloperidol S, T Tablets Injection Trifluoperazine 24.2 S, T Tablet 25 mg, 50 mg, 100 mg 25 mg / 5 ml 25 mg / ml 1.5 mg, 5 mg, 10 mg 5 mg / ml 5 mg, 10 mg

Medicines used in Mood Disorders

24.2.1 Medicines used in Depressive Disorders Amitriptyline Fluoxetine Hydrochloride Imipramine U U U Tablets Capsules Tablets 25 mg 20 mg 25 mg, 75 mg

24.2.2 Medicines used in Bipolar Disorders Lithium Carbonate 24.3 T Tablets 150 mg

Medicines used for Generalized Anxiety and Sleep Disorders Alprazolam Diazepam U U Tablets Tablets 0.25 mg, 0.5 mg 2 mg, 5 mg, 10 mg

28

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine

Category

Route of Administration/ Dosage Form Tablets

Strengths

Nitrazepam 24.4

U

5 mg, 10 mg

Medicines used for Obsessive Compulsive Disorders and Panic Attacks Clomipramine Hydrochloride S, T Tablets 10 mg, 25 mg

25. Medicines Acting on the Respiratory Tract
25.1 Antiasthmatic Medicines Aminophylline Beclomethasone Dipropionate Hydrocortisone Sodium Succinate Salbutamol Sulphate Theophylline Compounds 25.2 Antitussives Codeine Phosphate Dextromethorphan U U Tablets Syrup Tablets 10 mg 15 mg / 5 ml 30 mg U U Injection Inhalation 25 mg / ml 50 mg, 250 mg/dose 100 mg, 200 mg, 400 mg 2 mg, 4 mg 2 mg / 5 ml 100 mg / dose 100 mg, 200 mg

U

Injection

U

Tablets Syrup Inhalation Tablets

U

26. Solutions correcting Water, Electrolyte and Acid-Base Disturbances
26.1 Oral Oral Rehydration Salts 26.2 Parenteral U Powder for Solution As per IP

29

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Medicine

Category

Route of Administration/ Dosage Form Injection

Strengths

Glucose

U

5% isotonic 50% hypertonic 5% + 0.9% 0.9%

Glucose with Sodium Chloride Normal Saline N/2 Saline N/5 Saline

U U S, T S, T

Injection Injection Injection Injection Injection Injection Injection

Potassium Chloride U Ringer Lactate U

11.2% Sol.

Sodium Bicarbonate U 26.3 Miscellaneous Water for Injection U

Injection

2 ml, 5 ml, 10 ml

27. Vitamins and Minerals
Ascorbic Acid Calcium salts U U Tablets Tablets Tablets Tablets Tablets Tablets Tablets Tablets Capsules Injection Vitamin D3 (Ergocalciferol) S, T Capsules 50 mg 25 mg 5 mg 100 mg 5000 IU, 10,000 IU 50,000 IU 50,000 IU / ml 0.25 mg, 1 mg 100 mg, 500 mg 250 mg, 500 mg

Multivitamins U (As per Schedule V) Nicotinamide Pyridoxine Riboflavine Thiamine Vitamin A U U U U U

30

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Index
Sl. No. A 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. 21. 22. 23. 24. 25. 26. 27. 28. 29. 30. 31. 32. 33. B 34. 35. 36. 37. 38. 39. B.C.G Vaccine Barium Sulphate Beclomethasone Dipropionate Benzathine Benzylpenicillin Benzoic Acid + Salicylic Acid Benzoin Compound 25 20 29 5 18 20 Acenocoumarol Acetazolamide Acetyl Salicylic Acid Acriflavin+Glycerin Actinomycin D Activated Charcoal Acyclovir Adenosine Adrenaline Bitartrate Albendazole Albumin Allopurinol Alpha Interferon Alprazolam Aluminium Hydroxide + Magnesium Hydroxide Amikacin Aminophylline Amiodarone Amitriptyline Amlodipine Amoxicillin Amphotericin B Ampicillin Antisnake Venom Anti-D Immunoglobulin (Human) Antitetanus Human Immunoglobin Artesunate Ascorbic Acid Atenolol Atracurium Besylate Atropine Sulphate Azathioprine Azithromycin 15 27 2, 11, 16, 18 20 12 3 9, 18 16 3 5 15 2 12 28 21 6 29 16 28 17 5 8, 10 5 4, 25 25 25 10 30 17 26 1, 3, 27, 3, 12 6 Medicine Page No.

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NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Sl. No. 40. 41. 42. 43. 44. 45. 46. 47. 48. 49. 50. C 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. 61. 62. 63. 64. 65. 66. 67. 68. 69. 70. 71. 72. 73. 74. 75. 76. 77. 78. 79. 80. 81.

Medicine Benzyl Benzoate Benzylpenicillin Betamethasone Dipropionate Betaxolol Hydrochloride Bisacodyl Bleaching Powder Bleomycin Bretylium Tosylate Bromocriptine Mesylate Bupivacaine Hydrochloride Busulphan

Page No. 19 6 19 27 22 21 12 16 14 1 12

Calamine Calcium Gluconate Calcium Ipodate Calcium salts Carbamazepine Carbimazole Cefotaxime Ceftazidime Ceftriaxone Cefuroxime Centchroman Cephalexin Cetrimide Chloramphenicol Chlorhexidine Chloroquine Phosphate Chlorpheniramine Maleate Chlorpromazine Hydrochloride Chlorthalidone Ciprofloxacin Hydrochloride Cisplatin Clarithromycin Clofazimine Clomiphene Citrate Clomipramine Hydrochloride Clonidine Hydrochloride Clotrimazole Cloxacillin Coal Tar Codeine Phosphate Colchicine

19 4 20 30 4 25 6 6 6 6 24 6 21 6, 26 21 3, 10, 11 3 28 17 6, 26 12 6 7 24 29 17 8 6 19 29 2

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NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Sl. No. 82. 83. 84. 85. 86. 87. 88. D 89. 90. 91. 92. 93. 94. 95. 96. 97. 98. 99. 100. 101. 102. 103. 104. 105. 106. 107. 108. 109. 110. 111. 112. 113. 114. 115. E 116. 117. 118. 119.

Medicine Condoms Co-Trimoxazole (Trimethoprim + Sulphamethoxazole) Cryoprecipitate Cyanocobalamin Cyclophosphamide Cyclosporine Cytosine Arabinoside

Page No. 24 7, 11 15 14 12 12 12

D.P.T Vaccine Danazol Dapsone Desferrioxamine Mesylate Dexamethasone Dexchlorpheniramine Maleate Dextran-40 Dextran-70 Dextromethorphan Diazepam Diclofenac Dicyclomine Hydrochloride Didanosine Diethylcarbamazine Citrate Digoxin Dihydroergotamine Diloxanide Furoate Diltiazem Dimercaprol Diphtheria Antitoxin Dithranol Dobutamine Domperidone Dopamine Hydrochloride Doxapram Doxorubicin Doxycycline

25 12 7 4 3, 23 3 15 15 29 1, 4, 28 2 22 9 5 18 11 10 16 4 25 19 18 22 18 2 12 7

Efavirenz Enalapril Maleate Erythromycin Estolate Esmolol

9 17 7 16

33

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Sl. No. 120. 121. 122. 123. 124. 125. 126. 127. F 128. 129. 130. 131. 132. 133. 134. 135. 136. 137. 138. 139. 140. 141. 142. 143. 144. G 145. 146. 147. 148. 149. 150. 151. 152. 153. 154. 155. 156. H

Medicine Ethambutol Ether, Anaesthetic Ethinylestradiol + Levonorgesterol Ethinylestradiol + Norethisterone Ethinylestradiol Ethyl Alcohol 70% Ethyl Chloride Etoposide

Page No. 8 1 23 23 24 21 1 12

5-Fluorouracil Factor IX Complex (Coagulation Factors II,VII, IX, X)* Factor VIII Concentrate Ferrous Salt Fluconazole Flucytosine Flumazenil Fluorescein Fluoxetine Hydrochloride Flutamide Folic Acid Folinic Acid Formaldehyde IP Framycetin Sulphate Fresh Frozen Plasma Furazolidone Furosemide

13 15 15 14 8 8 4 19 28 13 14 13 21 18 15, 23 21

Gamma Benzene Hexachloride Gemcitabine Hydrochloride Gentamicin Gentian Violet Glibenclamide Glucagon Glucose with Sodium Chloride Glucose Glutaraldehyde Glycerin Glyceryl Trinitrate Griseofulvin

19 13 7, 26 21 24 24 30 30 21 19 16 8

34

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Sl. No. 157. 158. 159. 160. 161. 162. 163. 164. 165. 166. 167. I 168. 169. 170. 171. 172. 173. 174. 175. 176. 177. 178. 179. 180. 181. 182. 183. K 184. 185. L 186. 187. 188. 189. 190. 191. 192.

Medicine Haloperidol Halothane Heparin Sodium Hepatitis B Vaccine Homatropine Hormone Releasing IUD Hydrochlorothiazide Hydrocortisone Sodium Succinate Hydrogen Peroxide Hydroxyethyl Starch (Hetastarch) Hyoscine Butyl Bromide

Page No. 28 1 15, 18 25 27 24 21 3, 23, 29 21 15 22

Ibuprofen Imipramine Indinavir Insulin Injection (Soluble) Intermediate Acting Insulin (Lente/NPH Insulin) Intraperitoneal Dialysis Solution (of approximate composition) Iodine Iopanoic Acid Iron Dextran Isoflurane Isoniazid Isoprenaline Hydrochloride Isosorbide 5 Mononitrate/Dinitrate Isoxsuprine Hydrochloride Isphaghula IUD containing Copper

2 28 9 24 24 28 25 20 14 1 8 16 16 27 22 24

Ketamine Hydrochloride Ketoconazole

1 8

L- Asparaginase Lamivudine + Zidovudine Lamivudine +Nevirapine + Stavudine Lamivudine Levodopa+ Carbidopa Levothyroxine Lignocaine Hydrochloride + Adrenaline

13 9 9 9 14 25 1

35

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Sl. No. 193. 194. 195. 196. 197. 198. M 199. 200. 201. 202. 203. 204. 205. 206. 207. 208. 209. 210. 211. 212. 213. 214. 215. 216. 217. 218. 219. 220. 221. 222. 223. 224. 225. 226. N 227. 228. 229. 230. 231.

Medicine Lignocaine Hydrochloride Lignocaine Lithium Carbonate Local Anaesthetic, Astringent and Antiinflammatory Medicines Loperamide (Contraindicated for paediatric use) Losartan Potassium

Page No. 1, 16 20 28 22 23 17

Magnesium Sulphate Mannitol Measles Vaccine Mebendazole Medroxy Progesterone Acetate Meglumine Iothalamate Meglumine Iotroxate Melphalan Menadione Sodium Sulphite Mercaptopurine Metformin Methotrexate Methyl Cellulose Methyl Ergometrine Methyldopa Methylprednisolone Methylrosanilinium Chloride (Gentian Violet) Methylthioninium Chloride (Methylene blue) Metoclopramide Metoprolol Metronidazole Mexiletine Hydrochloride Miconazole Midazolam Mifepristone Mitomycin-C Morphine Sulphate Multivitamins

4 21 25 5 24 20 20 13 15 13 24 3, 13 27 27 17 23 18 4 22 16 7, 10 16 18, 26 2 27 13 2, 14 30

N/2 Saline N/5 Saline Nalidixic Acid Naloxone Nelfinavir

30 30 7 4 9

36

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Sl. No. 232. 233. 234. 235. 236. 237. 238. 239. 240. 241. 242. 243. 244. O 245. 246. 247. 248. 249. 250. 251. P 252. 253. 254. 255. 256. 257. 258. 259. 260. 261. 262. 263. 264. 265. 266. 267. 268. 269. 270.

Medicine Neomycin + Bacitracin Neostigmine Nevirapine Niclosamide Nicotinamide Nifedipine Nitrazepam Nitrofurantoin Nitrous Oxide Norethisterone Norfloxacin Normal Saline Nystatin

Page No. 19 26 9 5 30 17 29 7 1 24 7 30 9

Ofloxacin Omeprazole Ondansetron Oral Poliomyelitis Vaccine (Live Attenuated) Oral Rehydration Salts Oxygen Oxytocin

8 22 14 26 23, 29 1 27

Paclitaxel Pancuronium Bromide Paracetamol Penicillamine Pentamidine Isothionate Pentazocine Pethidine Hydrochloride Pheniramine Maleate Phenobarbitone Phenylephrine Phenytoin Sodium Physostigmine Salicylate Phytomenadione Pilocarpine Platelet Rich Plasma Polygeline Potassium Chloride Potassium Permanganate Povidone Iodine

13 26 2, 11 4 10, 11 2 2 3 4 27 4 27 15 27 16 15 30 21 19, 21

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NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Sl. No.

Medicine

Page No.

271. 272. 273. 274. 275. 276. 277. 278. 279. 280. 281. 282. 283. 284. 285. 286. 287. 288. 289. 290. Q 291. 292. R 293. 294. 295. 296. 297. 298. 299. 300. 301. S 302. 303. 304. 305. 306.

Pralidoxime Chloride (2-PAM) Praziquantel Prednisolone Prednisolone Acetate Prednisolone Sodium Phosphate Primaquine Procainamide Hydrochloride Procaine Benzylpenicillin Procarbazine Prochlorperazine Promethazine Propranolol Hydrochloride Propranolol Propyliodone Protamine Sulphate Pyrantel Pamoate Pyrazinamide Pyridostigmine Bromide Pyridoxine Pyrimethamine

4 5 3, 13, 23 27 27 10 16 6 13 22 2, 3, 22 11 16, 17 20 15 5 8 26 14, 30 10

Quinidine Quinine Sulphate

17 10

Rabies Immunoglobulin Rabies Vaccine Raloxifene Ranitidine Hydrocholoride Riboflavin Rifampicin Ringer Lactate Ritonavir Roxithromycin

25 26 13 22 30 7, 8 30 10 7

Salbutamol Sulphate Salicylic Acid Saquinavir Silver Nitrate Silver Sulphadiazine

29 19 10 19 19

38

NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Sl. No.

Medicine

Page No.

307 308. 309. 310. 311. 312. 313. 314. 315. 316. 317. 318. 319. 320. 321. 322. 323. T 324. 325. 326. 327. 328. 329. 330. 331. 332. 333. 334. 335. 336. 337. 338. 339. 340. 341. 342.

Sodium Meglumine Diatrizoate Sodium Bicarbonate Sodium Iothalamate Sodium Nitrite Sodium Nitroprusside* Sodium Stibogluconate Sodium Thiosulphate Sodium Valproate Spironolactone Stavudine Streptokinase Streptomycin Sulphate Succinyl Choline Chloride Sulfadoxine +Pyrimethamine Sulfasalazine Sulphacetamide Sodium Sulphadiazine

20 30 20 4 17 10, 11 4 5 21 9 18 8 26 10 3, 22 26 7

Tamoxifen Citrate Terazosin Terbutaline Sulphate Testosterone Tetanus Toxoid Tetracaine Hydrochloride Tetracycline Hydrochloride Tetracycline Theophylline Compounds Thiacetazone + Isoniazid Thiamine Thiopentone Sodium Timolol Maleate Tinidazole Trifluoperazine Trihexyphenidyl Hydrochloride Trimethoprim Tropicamide Tuberculin, Purified Protein Derivative

13 17 28 23 26 27 26 7 29 8 30 1 27 10 28 14 11 20 25

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NATIONAL LIST OF ESSENTIAL MEDICINES

2003

Sl. No. U 343. V 344. 345. 346. 347. 348. 349. W 350. 351. X 352. Z 353. 354.

Medicine

Page No.

Urokinase

18

Vancomycin Hydrochloride Verapamil Vinblastine Sulphate Vincristine Vitamin A Vitamin D3 (Ergocalciferol)

7 17 13 13 30 30

Warfarin Sodium Water for Injection

15 30

Xylometazoline

27

Zidovudine Zinc Oxide

9 19

"Note : The above list has been submitted to the Hon'ble Supreme Court of India in the case of SPL No. 3668 of 2003 in the matter of Union of India Vs. K.S. Gopinath & Others and would be subject to the final direction given by Hon'ble Court in the matter.”

40

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