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ENZYME

SOURCE/ORGAN

FUNCTION

1. Aminopeptidase

produced and It helps the enzymatic digestion of proteins. secreted by glands of the small Catalyze the cleavage of amino acids from the intestine amino terminus of protein or peptide substrates

2. pepsin

gastric glands

Responsible for breaking down proteins into smaller pieces, called polypeptides.

3. chymotrypsin

synthesized in the pancreas

A digestive enzyme that can perform proteolysis. Chymotrypsin preferentially cleaves peptide amide bonds where the carboxyl side of the amide bond (the P1 position) is a tyrosine, tryptophan, or phenylalanine.

Salivary amylase is produced in the mouth by the salivary glands and is the first enzyme involved in chemical digestion. 4. amylase

Breaks down starch or carbohydrates in food. Together, these enzymes break down the polysaccharide starch into di, tri and oliosaccharides, which are then broken down by other digestive enzymes into monosaccharides, such as glucose, which is absorbed and used as energy for the body

Pancreatic amylase is secreted by the pancreas into the duodenum, or first section of the small intestines.

5. Dissacharidase

brush border membrane of the small intestine produced in the pancreas, and is released in the small intestine

6. lipase

Break down certain types of sugars called disaccharides into simpler sugars called monosaccharides that are then absorbed into the body for further metabolism. Enzyme required to break down fats and lipids (to give di- and mono- glycerides, glycerol and free fatty acids)

7. Gastrin

Synthesized in G cells, which are located in gastric pits, primarily in the antrum region of the stomach Produced by cells of the duodenum Produced in the S cells of the duodenum Gastrointestinal system Synthesised by I-cells in the mucosal epithelium of the small intestine and secreted in the duodenum, the first segment of thesmall intestine Epithelial tissues

Major physiological regulator of gastric acid secretion. It also has an important trophic or growthpromoting influence on the gastric mucosa Converts trypsinogen (azymogen) into its active form trypsin, resulting in the subsequent activation of pancreatic digestive enzymes. A hormone that controls the secretions into the duodenum, and also separately, water homeostasis throughout the body Responsible for stimulating the digestion of fat and protein It also acts as a hunger suppressant. Recent evidence has suggested that it also plays a major role in inducing drug tolerance to opioids like morphine and heroin, and is partly implicated in experiences of pain hypersensitivity during opioid withdrawal

8. Enterokinase

9. Secretin

10. Cholecystokinin

11. Mucin

Key component in most gel-like secretions, serving functions from lubrication to cell signalling to forming chemical barriers

SOURCES: http://www.wikipedia.org http://www.livestrong.com/article/301300-major-digestive-enzymes-their-functions/#ixzz1kHuDS037 http://www.anyvitamins.com