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MCQ12/2555

1. Q=80%
warfarin 5 mg 6 N1=4.5, N2=4.5,
N3=5.25, N4=4.75, N5=5.25, N6=4.0
. S1
. S1 1 Q+5
. S1 4 Q+5
. S1 6
. ............................
2. warfarin
.
.
.
. ................
. ................
3. warfarin
. Friability
. Dissolution
. Disintegration
. Hardness
. Content uniformity
4. warfarin
. Warfarin 1
. paracetamol warfarin
. Mital stenosis target INR 2-3
. aPTT
. Platelet
5. warfarin
. warfarin Cat C
. protamine sulfate antidote
. ASA warfarin INR
. ......
. ......
Rx 44 CMU

6. thrombosis warfarin
. CYP 2C9 poor metabolizer
. E
. Phenobarbital
. etoricoxib
. ..
7. warfarin 3 5 mg 17.5 mg
4
. 3 mg
. 3 mg 5mg...
. 3 mg 5mg...
. 5 mg 14
. 5 mg 28
8.
. .............
. ...............
. ................
. ...................
. 5 mg
9. warfarin enantiomer
. 1
1
. 2
4
3
2
. 3
5
. 4
. 5
10. warfarin

.
.
.
.
.
Rx 44 CMU

11.
.
.
.
.
.
12.
. DTP
. Hep A
. BCG
. MMR
. OPV
13.
. BCG
. Hep B
. OPV
. JE
. IPV
14. adjuvant alum
.
.
.
.
.
15. DTP 3
. 1
. 2
. 3
. 4
. 6
Rx 44 CMU

16. 1 3
Hep B 2 3
.
.
.
. .....................
. .....................
17.
. IgA
. IgD
. IgE
. IgG
. IgM
18.
. Clarity test
. Sterility test
. Purity test
. Pyrogen test
. Toxicity test
19.
. dry heat
. gamma radiation
. filtration
. autoclave
. chemical treatment
20.
.
.
.
. ........
. ........

Rx 44 CMU

CD4 190 cell/mm3, anti HIV


(+), viral load pending
21. TB
. India ink
. Acid fast positive
. Gram (+) cocci
. Gram () bacilli
. Anaerobe
22.
. d4T + 3TC + NVP 2-4
. d4T + 3TC + EFV Rifampin
. DOT therapy
. Vitamin B6 Isoniazid
. PI
23.
. viral load
. HIV
.
. HIV
. ................................
24. Autoinducer NVP
.
.
.
.
. .......................
25. AIDs
. Lamivudine reverse transcriptase
. Ritonavir protease
. Stavudine
. ..................
. ....................
Rx 44 CMU

26. Stavudine (d4T)


.

27. DOT
.
.
.
.
. .....................
Rx 44 CMU

28. Stavudine
. metabolic alkalosis
. lipodystrophy
. osteoporosis
. .....................
. .....................
29. Ethambutol
. Mixing
. Drying
. Slugging
. Coating
. Tableting
30.
.
.
.
. .............
.

Rx 44 CMU

HCTZ
Gout Amiloride
+ HCTZ
31. Gout
.
. Amiloride
. HCTZ
. ........................
.
32. HCTZ
. Finger print FTIR
. Chromatogram TLC
. UV
. ..............
. .................
33. Allopurinol
. uric acid
. uric acid
. uric acid
. uric acid
. ......................
34. NSAIDs
. Aspirin
. Diclofenac
. Ibuprofen
. Indomethacin
. Piroxicam
35. Gout
.
.
.
.
.
Rx 44 CMU

36.
A
Allopurinol
Lactose
PVP
Magnesium stearate

B
0.3 g
10 g
15 ml
0.5 g

Allopurinol
Strach
PVP
Magnesium stearate
Colloidal silicon dioxide
Sodium lauryl sulfate
q.s. to

0.3 g
10 g
15 ml
0.5 g
1.0 g
1.5 g
100 g

q.s. to
100 g
Allopurinol
. A B Lactose
. B A Sodium lauryl sulfate
. ....................
. ..................
. ...................
37. colchicine
.
.
.
. ..
.
38. colchicines
. Retinopathy
. Diarrhea
. Dementia
. Cinchonism
. Nephrotoxicity

Rx 44 CMU

39.
. 1
.
. 2
. pack allopurinol lot
3
.
40. prednisolone 5 mg
.
.
.
.
. 3

Rx 44 CMU

40 2
chloramphenicol eye drop amoxicillin capsule 1x3 penicillin angioedema
41.
. amoxicillin ciprofloxacin
. amoxicillin azithromycin
. amoxicillin metronidazole
. chloramphenicol tobramycin
. chloramphenicol ciprofloxacin
42. chloramphenicol eye drop
. 1
.
. ...............
. ...............
. ...............
43. chloramphenicol eye drop pH= 8 buffer
. Boric acid sodium borate (pKa 9.82)
. Citric acid sodium citrate
. NaH2PO4 Na2HPO4
. Acetic acid sodium acetate
. ...................
44. chloramphenicol eye drop
.
.
.
.
.

45.
. Bacterial conjunctivitis
. Viral conjunctivitis
. Allergic conjunctivitis
. virus
Rx 44 CMU

46.
. Dexamethasone
. Polymixin B
. Oxymethazoline
. Phenylephrine
. .................
47.
.
.
.
.
.
48. Dexamethasone 0.3% ( Tf = 0.52 C
Tf Dexamethasone 1% = 0.16 C) Isotonic
. Hypotonic
. Hypertonic
. Isotonic
. Isoosmolarity
. Hypoosmolarity
Rx

oxymetazoline
0.1%
NaCl
qs.
Purified water qs. To
100 ml
49. oxymetazoline E 0.3 NaCl
isotonic
. 0.60 ml
. 0.67 ml
. 0.80 ml
. 0.87 ml
. 0.90 ml

Rx 44 CMU

50. angioedema ADR Type


. Type I
. Type II
. Type III
. Type IV
. Type VI


Dx: DU
Rx: Omeprazole 1 cap 1x1 OD

51. Omeprazole
. 1
. 15
.
.
. 1
52.
.
. omeprazole 30 1
. omeprazole 15
. ...............
. omeprazole 2
53. DU
.
.
.
.
.

Rx 44 CMU

54. ketoconazole omeprazole


ketoconazole
. omeprazole ketoconazole
. omeprazole ketoconazole
. ketoconazole omeprazole
. ketoconazole omeprazole
.
55.
. Omeprazole Ranitidine
. omeprazole antacid
. Ketoconazole Itraconazole
. ketoconazole fluconazole
. omeprazole ketoconazole
56. omeprazole MUPs enteric coated
.
. acid-labile
.
. .......
. ......
57. enteric coated omeprazole delayed release

. HPMC
. Cellulose acetate phthalate (CAP)
. MC
. Shallac
. PEG
58. Matrix
. Hydroxypropyl methyl cellulose
. Colloidal silicon dioxide
. Magnesium stearate
. Shallac
. PEG
Rx 44 CMU

59. USP
. Solubility
. Disintegration
. Hardness
. Uniformity of content
. Percent labeled amount
60.
. .........
. ........
. ...........
. .......
. Sodium starch glycolate

2
61.
. Contact dermatitis
. Eczema
. Allergy
. Tenia vesicolor
. Rosase
62.
. Clotrimazole
. Acyclovir
. Topical steroids
. Ketoconazole
. .
63. hydroxyzine hydroxyzine
. hydroxyzine
. hydroxyzine
. .....
Rx 44 CMU

64. hydroxyzine
. Citric acid
. PEG 400
. Hypomellose
. Sodium Chloride
. Menthol
65. Hydroxyzine
. Hypertension
. DM
. BPH
66. hydroxyzine
. Ethanolamine ether derivative
. Ethylenediamine derivative
. Phenothiazine derivative
. Piperazine derivative
. Propylamine derivative
67. Antihistamine
. Hydroxyzine
. Chlorphenhydramine
. Brompheniramine
. Triprolidine
. Cyproheptadine
68. Nasal corticosteroid spray
.
.
.
. 1
.

Rx 44 CMU

69. Nasal corticosteroid spray


. Rebound congestion
.
.
. bacteria rhinitis
.
70. rhinitis medicamentosa
. Pseudoephridrine
. Phenylephrine + Tripolidine
. Mometasone
. Budesonide
. Oxymetazoline
3
71.
. Conjugated estrogen
. Lynestrenol
. Ethenyl estradiol + Desogestrel
. Ethenyl estradiol + Norethisterone
. Ethenyl estradiol + Cyproterone acetate
72.
. prolactin
.
.
. .........
. ...........
73. Estrogen
. Estrogen 28
. Progestrin 28
. Estrogen + progestrin 28
. Estrogen 21 + progestrin 7
. Estrogen 16 + progestrin 12

Rx 44 CMU

74. HRT
. .....
.
. .......
. ........
. ......
75. ethinyl estradiol
. Thin layer chromatography
. Gas chromatography
. Mass Spectrometry
. UV
. High performance liquid chromatography
76.

. Single layer drug in adhesive


. Multiple layer drug n adhesive
. Drug reservoir system
. Matrix system
. .

Rx 44 CMU

77.
. ..
.
. ..
. ..
. ..
78. triphasic
.
.
.
.
. 3
79. bioequivalent
. AUC , Tmax
. AUC , Cmax
. AUC , half life
. Tmax , half life
. Cmax , half life
80.

Rx 44 CMU

.
.
. k
. accerelated stability
. Stokes equation
tonic clonic carbamazepine BID
81. carbamazepine
. Na Channel
. Ca Channel
. NMDA receptor
. GABA receptor
. GABA receptor
82.
. Trauma
. Brain tumor
. Otitis media
. Hypoglycemia
.
83. Carbamazepine
. ........
. .......
. Trigerminal neuralgia
. ............
. ...............
84. Carbamazepine
.
.
.
. .
. ..

Rx 44 CMU

85. Carbamazepine
. Clarithromycin
. Nevirapine
. Phenytoin
. .....
. ..........
86. Carbamazepine 200 mg extemporaneous 200 mg/tsp
150 ml
. 10
. 20
. 30
. 40
. 50
87. extemporaneous
. 14
.
.
. 1
.
88. Methylcellulose

. Newtonian
. Dilatants
. Pseudoplastic
. Plastic
. Brownians
89. Polymoph
.
.
.
.
.

Rx 44 CMU

90.
.
. ....................
. ....................
. ..................
. ....................

ciprofloxacin hyoscine
91. cystitis ciprofloxacin
. Cotrimoxazole
. Cefalexin
. Cloxacillin
. Doxycycline
. ......
92. ciprofloxacin
.
.
.
. DNA
.
93. ciprofloxacin
. Tendinitis
. Rhinitis
. Dizziness
. Diarrhea
.
94.
. 1
. hyoscine tolperisone
. ciprofloxacin
. ciprofloxacin cotrimoxazole
.

Rx 44 CMU

95. Hyoscine
. myasthenia gravis
. gut obstruction
.
. DU
.
Ibuprofen maculopapular rash 3

101.
.
.
.
. ............
. .............
102. Ibuprofen
maculopapular rash Gell and Coombs, 1963
. Immediate type
. Immune complex
. Antibody-dependent cytotoxic
. Delayed type
. Anaphylactic reaction
103. ibuprofen NSAIDs ()
. Aspirin
. Diclofenac
. Naproxen
. Indomethacin
. Piroxicam

Rx 44 CMU

104. Ibuprofen NSAIDs racemic mixtures S-isomer active

. racemic mixture
. S-isomer (+)-isomer
. S-isomer (-)-isomer
. R-isomer S-isomer
. R-isomer S-isomer
105. NSADs maculopapular
rash RR 16 (CI = 3.0-72.5)
. NSADs maculopapular rash
16
. NSADs maculopapular rash 16

. .....
. ......
. .....
106-108

Rx 44 CMU

106. antidote paracetamol


. 100 mol/L
. 200 mol/L
. 500 mol/L
. 1000 mol/L
. 1300 mol/L
107. Paracetamol
. Hepatocellular hepatitis
. Hepatic fibrosis
. Cholestitis hepatitis
. Granulomatous hepatitis
. .......
108. Antidote paracetamol
. ........
. ........
. .......
. .....
. N-acetylcysteine
109. paracetamol sustain release paracetamol immediate release
. Onset paracetamol sustain release paracetamol immediate release
. paracetamol sustain release paracetamol immediate release
. paracetamol sustain release paracetamol immediate release
. paracetamol sustain release paracetamol immediate release
. 2
110. FIFO
.
. .
. .
.
. .

Rx 44 CMU

1. bioequivalent
2. bioequivalent
3. (2 )

0
12
24
48
72
96
Redispersibility

A
10
8
7
6
5
4
60

B
10
9.8
9.5
9.5
9.0
9.0
4

. A sedimentation volume
. A caking
.
.
.
4. DV

Rx 44 CMU

C
10
9
8
7
7
7
20