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Acetylcholine + + +
Histamine + + + + +
Serotonin + +
Bradikinin + + + + +
SRS-A + +
Prostaglandin + + +
Perawatan dan pengobatan
(kolaburatif)
• Epinephrine HCl
• Pasang torniquet
• Pelihara ventilasi
• Pasang infus, vasopresor, aminophylin,
diphenhydramine,
• Adrenokortikosteroid
• Antihistamin
Symptoms
• Laryngeal edema
• Bronchoconstriction
• Hypotension.
ASSESSMENT
Interview:
• patient’s identity,
• chief complaint,
• history of present illness
Identitas pasien
(Patient Identification)
• penderita ditidurkan
• hidrokortison dan antihistamin
Reaksi Akut (muntah, lemah, wheezing,
dada berat, sesak nafas, sembab, aritmia)
• posisi shock, monitoring VS
• antihistamin, hidrokortison IV
• infus bila tensi drop
• obst sal pernafasan: adrenalin
• observasi ICU
Reaksi berat (hilang kesadaran, tensi
turun, circulatory arrest.
• mouth to mouth, ET
• O2
• Cairan intrevena
• Observasi ICU
Pencegahan
• Pemakaian obat dng indikasi medis
jelas.
• Anamnesa teliti
• Hindari obat dng struktur sama dg obat
pernah alergi.
• Tes kulit.
• Pemakaian obat “alergen” dg
pengawasan.
• Emergency kit