Science & Mathematics

Sharks are some of the most fascinating and ecologically important, yet most threatened and misunderstood animals on Earth. More often feared than revered, their role as predators of the deep has earned them a reputation as a major threat to humans. But the truth is that sharks are not a danger to us—they’re in danger from us. In Why Sharks Matter, marine conservation biologist Dr. David Shiffman urges us to overcome our misconceptions and embrace sharks as the imperiled and elegant ocean guardians they really are. Touching on everything from Shark Week to shark fin soup, overfishing to marine sanctuaries, Shiffman reveals why sharks are in trouble, why we should care, and how we can save them. A witty narrative highlighting the author’s fascinating experiences working with sharks, this exploration of the essential principles of shark conservation science and policy is full of amazing facts about both little-known and iconic shark species. It spells out how healthy shark populations support marine ecosystems—and the coastal economies that depend on them—while carefully explaining what scientists, conservationists, and readers can do to help. With his signature pragmatism and irreverence, Shiffman doesn’t shy away from explaining why much of what you’ve heard about sharks and how to save them is wrong. Perfect for shark enthusiasts, Why Sharks Matter provides an approachable, informative guide to the world of shark conservation, and an insider’s introduction to the passionate, brilliant people who work to protect our oceans. This fun read will have you looking at sharks with a fresh perspective and an understanding that their survival is crucial to the survival of another apex predator—ourselves.

An important—and intimate—interrogation of how we treat mental illness and how we understand ourselves In the early 1960s, JFK declared that science would take us to the moon. He also declared that science would make the “remote reaches of the mind accessible” and cure psychiatric illness with breakthrough medications. We were walking on the moon within the decade. But today, psychiatric cures continue to elude us—as does the mind itself. Why is it that we still don’t understand how the mind works? What is the difference between the mind and the brain? And given all that we still don’t know, how can we make insightful, transformative choices about our psychiatric conditions? When Daniel Bergner’s younger brother was diagnosed as bipolar and put on a locked ward in the 1980s, psychiatry seemed to have achieved what JFK promised: a revolution of chemical solutions to treat mental illness. Yet as Bergner’s brother was deemed a dire risk for suicide and he and his family were told his disorder would be lifelong, he found himself taking heavy doses of medications with devastating side effects. Now, in recounting his brother’s journey alongside the gripping, illuminating stories of Caroline, who is beset by the hallucinations of psychosis, and David, who is overtaken by depression, Bergner examines the evolution of how we treat our psyches. He reveals how the pharmaceutical industry has perpetuated our biological view of the mind and our drug-based assumptions about treatment—despite the shocking price paid by many patients and the problematic evidence of drug efficacy. And he takes us into the pioneering labs of today’s preeminent neuroscientists, sharing their remarkably candid reflections and fascinating new theories of treatment. The Mind and the Moon raises profound questions about how we understand ourselves and the essential human divide between our brains and our minds. This is a book of thought-provoking reframings, delving into the science—and spirit—of our psyches. It is about vulnerability and personal dignity, the terrifying choices confronted by families and patients, and the prospect of alternatives. In The Mind and the Moon, Bergner beautifully explores how to seek a deeper engagement with ourselves and one another—and how to find a better path toward caring for our minds. Supplemental enhancement PDF accompanies the audiobook.

This program is read by the author. Paul Craddock's Spare Parts offers an original look at the history of medicine itself through the rich, compelling, and delightfully macabre story of transplant surgery from ancient times to the present day. How did an architect help pioneer blood transfusion in the 1660's? Why did eighteenth-century dentists buy the live teeth of poor children? And what role did a sausage skin and an enamel bath play in making kidney transplants a reality? We think of transplant surgery as one of the medical wonders of the modern world. But transplant surgery is as ancient as the pyramids, with a history more surprising than we might expect. Paul Craddock takes us on a journey - from sixteenth-century skin grafting to contemporary stem cell transplants - uncovering stories of operations performed by unexpected people in unexpected places. Bringing together philosophy, science and cultural history, Spare Parts explores how transplant surgery constantly tested the boundaries between human, animal, and machine, and continues to do so today. Witty, entertaining, and at times delightfully macabre, Spare Parts shows us that the history - and future - of transplant surgery is tied up with questions about not only who we are, but also what we are, and what we might become. A Macmillan Audio production from St. Martin's Press.

World-renowned future forecaster, game designer, and NEW YORK TIMES bestselling author Jane McGonigal gives us the tools to imagine the future without fear. “An accessible, optimistic field guide to the future.”—San Francisco Chronicle “Reading this book is like sitting down with a creative, optimistic friend—and getting up as a new version of yourself.” – Daniel H. Pink, New York Times bestselling author of When The COVID-19 pandemic, increasingly frequent climate disasters, a new war — events we might have called “unimaginable” or “unthinkable” in the past are now reality. Today it feels more challenging than ever to feel unafraid, hopeful, and equipped to face the future with optimism. How do we map out our lives when it seems impossible to predict what the world will be like next week, let alone next year or next decade? What we need now are strategies to help us recover our confidence and creativity in facing uncertain futures. In Imaginable, Jane McGonigal draws on the latest scientific research in psychology and neuroscience to show us how to train our minds to think the unthinkable and imagine the unimaginable. She invites us to play with the provocative thought experiments and future simulations she’s designed exclusively for this book, with the goal to: 1. Build our collective imagination so that we can dive into the future and envision, in surprising detail, what our lives will look like ten years from now 2. Develop the courage and vision to solve problems creatively 3. Take actions and make decisions that will help shape the future we desire 4. Access “urgent optimism,” an unstoppable force within each of us that activates our sense of agency Imaginable teaches us to be fearless, resilient, and bold in realizing a world with possibilities we cannot yet imagine—until reading this transformative, inspiring, and necessary book

2022 Genesis Prize Laureate The exclusive, first-hand, behind-the-scenes story of how Pfizer raced to create the first Covid-19 vaccine, told by Pfizer’s Chairman and CEO Dr. Albert Bourla. A riveting, fast-paced, inside look at one of the most incredible private sector achievements in history, Moonshot recounts the intensive nine months in 2020 when the scientists at Pfizer, under the visionary leadership of Dr. Albert Bourla, made “the impossible possible”—creating, testing, and manufacturing a safe and effective Covid-19 vaccine that previously would have taken years to develop.  Dr. Bourla chronicles how the brilliant, dedicated minds at Pfizer, under the enormous strains of the global pandemic, overcame a series of crises that were compounded by social and political unrest, and reveals the doubts, decisions, obstacles, and failures they encountered. As Dr. Bourla makes clear, Pfizer’s success wasn’t due to luck; it was because of preparation driven by four simple values—Courage, Excellence, Equity, and Joy. Moonshot is a story of leadership under the most unprecedented circumstances—how Dr. Bourla, a Greek immigrant, a child of Holocaust survivors, and a veterinarian, became the head of one of the world’s largest corporations and initiated a dramatic transformation of the organization just before a global health crisis would serve to test the organization, its scientists, and its leader, like never before. Moonshot describes best practices that can be used to address the multiple, unprecedented challenges our world faces, reveals Pfizer’s implementation of scientific breakthroughs at a record-breaking pace, and offers leadership lessons that can help anyone successfully manage their own seemingly unsolvable problems. As Dr. Bourla explains, “I am sharing the story of our moonshot—the challenges we faced, the lessons we learned, and the core values that allowed us to make it happen—in hopes that it might inspire and inform your own moonshot, whatever that may be.”   Supplemental enhancement PDF accompanies the audiobook.

From a renowned surgeon and historian with five decades of experience comes a remarkable history of surgery’s development—spanning the Stone Age to the present day—blending meticulous medical studies with lively and skillful storytelling. There are not many events in life that can be as simultaneously life-frightening and life-saving as a surgical operation. Yet, in America, tens-of-millions of major surgical procedures are performed annually but few of us pause to consider the magnitude of these figures because we have such inherent confidence in surgeons. And, despite passionate debates about healthcare and the endless fascination with surgical procedures, most of us have no idea how surgeons came to be because the story of surgery has never been fully told. Now, Empire of the Scalpel elegantly reveals the fascinating history of surgery’s evolution from its earliest roots in Europe through its rise to scientific and social dominance in the United States. From the 16th-century saga of Andreas Vesalius and his crusade to accurately describe human anatomy while appeasing the conservative clergy who clamored for his burning at the stake, to the hard-to-believe story of late-19th century surgeons’ apathy to Joseph Lister’s innovation of antisepsis and how this indifference led to thousands of unnecessary surgical deaths, Empire of the Scalpel is both a global history and a uniquely American tale. You’ll discover how in the 20th century the US achieved surgical world supremacy heralded by the Nobel Prize–winning, seemingly impossible feat of transplanting a kidney and how the heart-lung machine was developed, along with much more. Today, the list of possible operations is almost infinite—from knee and hip replacement to heart bypass and transplants to fat reduction and rhinoplasty—and Rutkow draws on his five-decade career to show us how we got here. Authoritative, captivating, and comprehensive, Empire of the Scalpel portrays the evolution of surgery in all its dramatic and life-enhancing complexity and shows that its history is truly one awe-inspiring triumph after another.

“As David Robson makes plain in this compelling book, the way we think about the world can profoundly shape how we navigate it. Based in science and packed with smart advice, The Expectation Effect will expand your mind—and maybe even extend your life.” —Daniel Pink, New York Times bestselling author of When, Drive, and To Sell Is Human A journey through the cutting-edge science of how our mindset shapes every facet of our lives, revealing how your brain holds the keys to unlocking a better you What you believe can make it so. You’ve heard of the placebo effect and how sugar pills can accelerate healing. But did you know that sham heart surgeries often work just as well as placing real stents? Or that people who think they’re particularly prone to cardiovascular disease are four times as likely to die from cardiac arrest? Such is the power and deadly importance of the expectation effect—how what we think will happen changes what does happen. Melding neuroscience with narrative, science journalist David Robson takes readers on a deep dive into the many life zones the expectation effect permeates. We see how people who believe stress is beneficial become more creative when placed under strain. We see how associating aging with wisdom can add seven plus years to your life. People say seeing is believing but, over and over, Robson proves that the converse is truer: believing is seeing. The Expectation Effect is not woo-woo. You cannot think your way into a pile of money or out of a cancer diagnosis. But just because magical thinking is nonsense doesn’t mean rational magic doesn’t exist. Pointing to accepted psychology and objective physiology, Robson gives us the practical takeaways we need to improve our fitness, productivity, intelligence, and happiness. Any reader who wants to take their fate into their own hands need only pick up this book. A Macmillan Audio production from Henry Holt and Company.

We have the impression that the solar system is perfectly regular like a clock or a planetarium instrument. On a short timescale it is. But, seen in a longer perspective, the planets, and their satellites, have exciting lives, full of events. For example, did you know that Saturn’s moon, Titan, boasts lakes which contain liquid methane surrounded by soaring hills and valleys, exactly as the earth did before life evolved on our fragile planet? Or that Mercury is the shyest planet? Or, that Mars’s biggest volcano is one hundred times the size of Earth’s, or that its biggest canyon is ten times the depth of the Grand Canyon, or that it wasn’t always red, but blue? The culmination of a lifetime of astronomy and wonder, Paul Murdin’s enchanting new book reveals everything you ever wanted to know about the planets, their satellites, and our place in the solar system.

How did one of the world’s preeminent marine conservation scientists fall in love with coral reefs? We first meet Callum as a young student who had never been abroad, spending a summer helping to map the unknown reefs of Saudi Arabia. From that moment, when Callum first cleared his goggles, he never looked back. He went on to survey Sharm al-Sheikh, and from there he would dive into the deep in the name of research all over the world, from Australia’s imperiled Great Barrier Reef to the hardier reefs of the Caribbean. Reef Life is filled with astonishing stories of adventure and the natural world, which are by turns lyrical and laced with a wonderful wry humor. Callum illuminates the science of our oceans and reefs and his book, combined with the stunning photographs from Alex Mustard, will also commit readers to support Callum’s goal to preserve 10 percent of the world’s oceans.

A very timely history of disease outbreaks, from the authors of Quackery: stories of outbreaks (and their patient zeros), plus chapters on the science, culture, and cures for different types of epidemics and pandemics. Popular reading on a timely topic.

Prize–winning essayist turns to the imagination as a spiritual guide and material method of living through climate disruption, as climate change and broad extinction forever alter our place on the planet and our lives together. Scott Russell Sanders shows how imagination, linked to compassion, can help us solve the urgent ecological and social challenges we face. While reflecting on the conditions needed for human flourishing, he tells the story of his own intellectual and moral journey from childhood religion to an adult philosophy of life. That philosophy is tested when his first wife and then their son fall ill. Compelled to leave their beloved old house, they design a new one, and then transform their vision into a home and their raw city lot into a garden

The gripping true story of a Supreme Court civil rights battle to keep biotech companies from owning our genes.   Today, we give away our personal information to websites, our data is routinely hacked, the images and texts that we post on social media are no longer ours. But what we do own—what makes us who we are—is our DNA. It would seem that no one could take that from us. Not so. The human genome was first mapped and sequenced in 2001, and by 2005, experts estimated that patents covered nearly 20% of the human genome. In its hundred-year history, the ACLU had never filed a patent case, but it came to view the ownership of human genes as a fundamental civil rights issue. The Genome Defense is a fascinating behind-the-scenes account of a committed group of activists, scientists, academics, and physicians, spearheaded by a brilliant legal team. They sued Myriad Genetics, the company that patented the famous BRCA1 and BRCA2 genes—warning bells for hereditary breast and ovarian cancer—making the test for these genes unaffordable for many women. Jorge L. Contreras, a professor of law and human genetics, introduces us to the key players in this important legal battle. He lays out the ACLU’s ground-breaking courtroom strategy in accessible and eye-opening detail, retelling early missteps to the final dramatic argument before the U.S. Supreme Court. He also describes the Obama Administration’s unprecedented involvement in the case, pitting the Patent Office against its sister federal agencies and embroiling personalities at the highest levels of government. Like The Immortal Life of Henrietta Lacks, The Genome Defense delves into the underbelly of our technological age of discovery, where the law struggles to keep pace with scientific advancement and corporate greed.

The full inside story of the high-stakes, global race for the lifesaving vaccine to end the pandemic Heroic science. Chaotic politics. Billionaire entrepreneurs. Award-winning journalist Brendan Borrell brings the defining story of our times alive through compulsively readable, first-time reporting on the players leading the fight against a vicious virus. The First Shots, soon to be the subject of an HBO limited series with superstar director and producer Adam McKay (Succession, Vice, The Big Short), draws on exclusive, high-level access to weave together the intense vaccine-race conflicts among hard-driving, heroic scientists and the epic rivalries among Washington power players that shaped 18 months of fear, resolve, and triumph. From infectious disease expert Michael Callahan, an American doctor secretly on the ground in Wuhan in January 2020 to gauge the terrifying ravages of Disease X; to Robert (Dr. Bob) Kadlec, one of Operation Warp Speed’s architects, whose audacious plans for the American people run straight into the buzz saw of the Trump White House factions; to Stéphane Bancel of upstart Moderna Therapeutics going toe-to-toe with pharma behemoth Pfizer, The First Shots lays bare, in a way we have not seen, the full stunning story behind the medical science “moon shot” of our lifetimes.

In a world that seems so troubled, how do we hold on to hope? This program is read by the authors and includes a bonus PDF. Looking at the headlines—the worsening climate crisis, a global pandemic, loss of biodiversity, political upheaval—it can be hard to feel optimistic. And yet hope has never been more desperately needed. In this urgent audiobook, Jane Goodall, the world's most famous living naturalist, and Douglas Abrams, the internationally bestselling co-author of The Book of Joy, explore through intimate and thought-provoking dialogue one of the most sought after and least understood elements of human nature: hope. In The Book of Hope, Jane focuses on her "Four Reasons for Hope": The Amazing Human Intellect, The Resilience of Nature, The Power of Young People, and The Indomitable Human Spirit. Drawing on decades of work that has helped expand our understanding of what it means to be human and what we all need to do to help build a better world, The Book of Hope touches on vital questions, including: How do we stay hopeful when everything seems hopeless? How do we cultivate hope in our children? What is the relationship between hope and action? Filled with moving and inspirational stories and photographs from Jane’s remarkable career, The Book of Hope is a deeply personal conversation with one of the most beloved figures in the world today. While discussing the experiences that shaped her discoveries and beliefs, Jane tells the story of how she became a messenger of hope, from living through World War II to her years in Gombe to realizing she had to leave the forest to travel the world in her role as an advocate for environmental justice. And for the first time, she shares her profound revelations about her next, and perhaps final, adventure. The second audiobook in the Global Icons Series—which launched with the instant classic The Book of Joy with His Holiness the Dalai Lama and Archbishop Desmond Tutu—The Book of Hope is a rare and intimate look not only at the nature of hope but also into the heart and mind of a woman who revolutionized how we view the world around us and has spent a lifetime fighting for our future. There is still hope, and this book will help guide us to it. A Macmillan Audio production from Celadon Books

NATIONAL BESTSELLER “Magnificent.” —The New York Times * “Beguiling, observant, and howlingly funny.” —San Francisco Chronicle * “Spectacular.” —Star Tribune (Minneapolis) * “Full of astonishments.” —The Boston Globe Susan Orlean—the beloved New Yorker staff writer hailed as “a national treasure” by The Washington Post and the author of the New York Times bestseller The Library Book—gathers a lifetime of musings, meditations, and in-depth profiles about animals. “How we interact with animals has preoccupied philosophers, poets, and naturalists for ages,” writes Susan Orlean. Since the age of six, when Orlean wrote and illustrated a book called Herbert the Near-Sighted Pigeon, she’s been drawn to stories about how we live with animals, and how they abide by us. Now, in On Animals, she examines animal-human relationships through the compelling tales she has written over the course of her celebrated career. These stories consider a range of creatures—the household pets we dote on, the animals we raise to end up as meat on our plates, the creatures who could eat us for dinner, the various tamed and untamed animals we share our planet with who are central to human life. In her own backyard, Orlean discovers the delights of keeping chickens. In a different backyard, in New Jersey, she meets a woman who has twenty-three pet tigers—something none of her neighbors knew about until one of the tigers escapes. In Iceland, the world’s most famous whale resists the efforts to set him free; in Morocco, the world’s hardest-working donkeys find respite at a special clinic. We meet a show dog and a lost dog and a pigeon who knows exactly how to get home. Equal parts delightful and profound, enriched by Orlean’s stylish prose and precise research, these stories celebrate the meaningful cross-species connections that grace our collective existence.

CNN chief medical correspondent Sanjay Gupta, MD, offers an accessible, data-packed answer to our biggest questions about Covid-19: What have we learned about this pandemic and how can we prepare for—or prevent—the next one? As America’s favorite frontline Covid-19 health journalist, Dr. Sanjay Gupta has barely left his primetime seat in his makeshift studio basement since the pandemic began (other than to perform brain surgery). He’s had insider access to the drama’s unfolding, including exclusive conversations with the world’s top public health experts and behind-the-scenes scientists racing to find treatments and cures. And now he’s sharing what he’s learned in a book that will answer not only all our questions about what happened, but also about how our world will change in the years ahead, even once we’re back to “normal.” Gupta argues that we need to prepare for a new era where pandemics will be more frequent, and possibly even more deadly. As the doctor who’s been holding America’s hand through the crisis with compassion, clarity, and well-earned wisdom, he gives you the unvarnished story behind the pandemic, including insights about the novel virus’s behavior, and offers practical tools to ready ourselves for what lies ahead. He answers critical questions: Can we stamp out the virus for good (and if not, how do we live with it)? Should we put our parents in a nursing home? Where should we live? What should we stockpile? What should we know before taking a trip? Does it make sense to spend more on health insurance to deal with any long-term effects? How do you decide when it’s safe to go to a public pool or schedule elective surgery? What should Covid survivors know about protecting their future health? What if you become a long-hauler with chronic health challenges stemming? World War C will give you hope for the future along with real information that leaves you more resilient and secure.

Making sense of sound is one of the hardest jobs we ask our brains to do. In Of Sound Mind, Nina Kraus examines the partnership of sound and brain, showing for the first time that the processing of sound drives many of the brain's core functions. Our hearing is always on—we can't close our ears the way we close our eyes—and yet we can ignore sounds that are unimportant. We don't just hear; we engage with sounds. Kraus explores what goes on in our brains when we hear a word—or a chord, or a meow, or a screech. Our hearing brain, Kraus tells us, is vast. It interacts with what we know, with our emotions, with how we think, with our movements, and with our other senses. Auditory neurons make calculations at one-thousandth of a second; hearing is the speediest of our senses. Sound plays an unrecognized role in both healthy and hurting brains. Kraus explores the power of music for healing as well as the destructive power of noise on the nervous system. She traces what happens in the brain when we speak another language, have a language disorder, experience rhythm, listen to birdsong, or suffer a concussion. Kraus shows how our engagement with sound leaves a fundamental imprint on who we are. The sounds of our lives shape our brains, for better and for worse, and help us build the sonic world we live in.

In the tradition of Rachel Carson’s groundbreaking environmental classic Silent Spring, an award-winning entomologist and conservationist explains the importance of insects to our survival, and offers a clarion call to avoid a looming ecological disaster of our own making. Drawing on thirty years of research, Goulson has written an accessible, fascinating, and important book that examines the evidence of an alarming drop in insect numbers around the world. “If we lose the insects, then everything is going to collapse,” he warned in a recent interview in the New York Times—beginning with humans’ food supply. The main cause of this decrease in insect populations is the indiscriminate use of chemical pesticides. Hence, Silent Earth’s nod to Rachel Carson’s classic Silent Spring which, when published in 1962, led to the global banning of DDT. This was a huge victory for science and ecological health at the time. Yet before long, new pesticides just as lethal as DDT were introduced, and today, humanity finds itself on the brink of a new crisis. What will happen when the bugs are all gone? Goulson explores the intrinsic connection between climate change, nature, wildlife, and the shrinking biodiversity and analyzes the harmful impact for the earth and its inhabitants.   Meanwhile we have all read stories about hive collapse syndrome affecting honeybee colonies and the tragic decline of monarch butterflies in North America, and more. But it is not too late to arrest this decline, and Silent Earth should be the clarion call. Smart, eye-opening, and essential, Silent Earth is a forceful call to action to save our world, and ultimately, ourselves. Supplemental enhancement PDF accompanies the audiobook.

NAMED A BEST BOOK OF THE YEAR BY WORLD ECONOMIC FORUM, AARP, GREATER GOOD, AND INC. The End of Bias is a transformative, groundbreaking exploration into how we can eradicate unintentional bias and discrimination, the great challenge of our age. Unconscious bias: persistent, unintentional prejudiced behavior that clashes with our consciously held beliefs. We know that it exists, to corrosive and even lethal effect. We see it in medicine, the workplace, education, policing, and beyond. But when it comes to uprooting our prejudices, we still have far to go. With nuance, compassion, and ten years' immersion in the topic, Jessica Nordell weaves gripping stories with scientific research to reveal how minds, hearts, and behaviors change. She scrutinizes diversity training, deployed across the land as a corrective but with inconsistent results. She explores what works and why: the diagnostic checklist used by doctors at Johns Hopkins Hospital that eliminated disparate treatment of men and women; the preschool in Sweden where teachers found ingenious ways to uproot gender stereotyping; the police unit in Oregon where the practice of mindfulness and specialized training has coincided with a startling drop in the use of force. Captivating, direct, and transformative, The End of Bias: A Beginning brings good news. Biased behavior can change; the approaches outlined here show how we can begin to remake ourselves and our world. A Macmillan Audio production from Metropolitan Books

NATIONAL BESTSELLER “An optimistic view on why collective action is still possible—and how it can be realized.” —The New York Times “As far as heroic characters go, I’m not sure you could do better than Katharine Hayhoe.” —Scientific American “It’s not an exaggeration to say that Saving Us is one of the more important books about climate change to have been written.” —The Guardian United Nations Champion of the Earth, climate scientist, and evangelical Christian Katharine Hayhoe changes the debate on how we can save our future. Called “one of the nation's most effective communicators on climate change” by The New York Times, Katharine Hayhoe knows how to navigate all sides of the conversation on our changing planet. A Canadian climate scientist living in Texas, she negotiates distrust of data, indifference to imminent threats, and resistance to proposed solutions with ease. Over the past fifteen years Hayhoe has found that the most important thing we can do to address climate change is talk about it—and she wants to teach you how. In Saving Us, Hayhoe argues that when it comes to changing hearts and minds, facts are only one part of the equation. We need to find shared values in order to connect our unique identities to collective action. This is not another doomsday narrative about a planet on fire. It is a multilayered look at science, faith, and human psychology, from an icon in her field—recently named chief scientist at The Nature Conservancy. Drawing on interdisciplinary research and personal stories, Hayhoe shows that small conversations can have astonishing results. Saving Us leaves us with the tools to open a dialogue with your loved ones about how we all can play a role in pushing forward for change.

NEW YORK TIMES BESTSELLER “Uncontrolled Spread is everything you’d hope: a smart and insightful account of what happened and, currently, the best guide to what needs to be done to avoid a future pandemic." —Wall Street Journal “Informative and well paced.”—The Guardian “An intense ride through the pandemic with chilling details of what really happened. It is also sprinkled with notes of true wisdom that may help all of us better prepare for the future.”—Sanjay Gupta, MD, chief medical correspondent, CNNP hysician and former FDA commissioner Scott Gottlieb asks: Has America’s COVID-19 catastrophe taught us anything? In Uncontrolled Spread, he shows how the coronavirus and its variants were able to trounce America’s pandemic preparations, and he outlines the steps that must be taken to protect against the next outbreak. As the pandemic unfolded, Gottlieb was in regular contact with all the key players in Congress, the Trump administration, and the drug and diagnostic industries. He provides an inside account of how level after level of American government crumbled as the COVID-19 crisis advanced. A system-wide failure across government institutions left the nation blind to the threat, and unable to mount an effective response. We’d prepared for the wrong virus. We failed to identify the contagion early enough and became overly reliant on costly and sometimes divisive tactics that couldn’t fully slow the spread. We never considered asymptomatic transmission and we assumed people would follow public health guidance. Key bureaucracies like the CDC were hidebound and outmatched. Weak political leadership aggravated these woes. We didn’t view a public health disaster as a threat to our national security. Many of the woes sprung from the CDC, which has very little real-time reporting capability to inform us of Covid’s twists and turns or assess our defenses. The agency lacked an operational capacity and mindset to mobilize the kind of national response that was needed. To guard against future pandemic risks, we must remake the CDC and properly equip it to better confront crises. We must also get our intelligence services more engaged in the global public health mission, to gather information and uncover emerging risks before they hit our shores so we can head them off. For this role, our clandestine agencies have tools and capabilities that the CDC lacks. Uncontrolled Spread argues we must fix our systems and prepare for a deadlier coronavirus variant, a flu pandemic, or whatever else nature -- or those wishing us harm -- may threaten us with. Gottlieb outlines policies and investments that are essential to prepare the United States and the world for future threats.

A journey into the heartbeat of life on Earth.   Millennia ago, when we first began puzzling over the mysteries of the human body, one organ stood out as vital. The heart was warm, it was central, and it moved as it pumped blood. The ancient Egyptians treated it with reverence, mummifying it separately from the body so that the soul inside it could be weighed. Aristotle believed that it was the seat of consciousness. Over the centuries, science has dispelled the myths, but our fascination with the heart has endured.     From the origins of circulation, still evident in some microorganisms today, to the enormous hearts of blue whales, we journey with Bill to beaches where horseshoe crabs are being harvested for their life-saving blood, and under the sea to learn about the world’s most natural antifreeze, flowing through the veins of icefish. And we follow him through human history, too, as scientists hypothesize wrongly and rightly about what is arguably our most important organ, ultimately developing the technologies that have helped us study the heart—and now, in the most cutting-edge labs, the tools that will help us regenerate it.   Deeply researched and engagingly told, Pump is a fascinating natural history sure to be loved by readers of Mary Roach and Bill Bryson.

An Indie Next Selection for September 2021 From the author of the bestselling #ReadWithJenna/TODAY Show book club pick Late Migrations: A Natural History of Love and Loss For the past four years, Margaret Renkl’s columns have offered readers of The New York Times a weekly dose of natural beauty, human decency, and persistent hope from her home in Nashville. Now more than sixty of those pieces have been brought together in this sparkling new collection. “People have often asked me how it feels to be the ‘voice of the South,’” writes Renkl in her introduction. “But I’m not the voice of the South, and no one else is, either.” There are many Souths—red and blue, rural and urban, mountain and coast, Black and white and brown—and no one writer could possibly represent all of them. In Graceland, At Last, Renkl writes instead from her own experience about the complexities of her homeland, demonstrating along the way how much more there is to this tangled region than many people understand. In a patchwork quilt of personal and reported essays, Renkl also highlights some other voices of the South, people who are fighting for a better future for the region. A group of teenagers who organized a youth march for Black Lives Matter. An urban shepherd whose sheep remove invasive vegetation. Church parishioners sheltering the homeless. Throughout, readers will find the generosity of spirit and deep attention to the world, human and nonhuman, that keep readers returning to her columns each Monday morning. From a writer who “makes one of all the world’s beings” (NPR), Graceland, At Last is a book full of gifts for Southerners and non-Southerners alike.

“Perhaps one lesson to draw from the pandemic, with help from books like this one, is that the ICU experience can be changed for the better” (The Washington Post) for both patients and their families. You will learn how in this timely, urgent, and compassionate work by a world-renowned critical care doctor. Over the next ten years, 40 to 60 million people in this country will be admitted to the ICU. Most of these hospitalizations will be sudden, unexpected, and harrowing experiences that can alter patients and their families physically and emotionally, with effects that endure for years. In this rich blend of science, medical history, profoundly humane patient stories, and personal reflection, Dr. Wes Ely describes his mission to prevent patients from being inadvertently harmed by the technology that is keeping them alive. You will experience the world of critical care through the eyes of a physician who drastically changed his clinical practice to offer person-centered health care, and through cutting-edge research convinced others to do the same. For decades, ICU survivors left the hospital with disabling symptoms including newly acquired dementia, depression, PTSD, and nerve damage, all now recognized as Post Intensive Care Syndrome, or PICS. Dr. Ely’s groundbreaking investigations advanced the understanding of PICS and introduced crucial changes that reshaped intensive care: minimizing sedation, maximizing mobility, listening to the family, and providing supportive aftercare. Dr. Ely shows that there are ways to bring humanity into the ICU and that “technology plus touch” is the future of health care and is a proven path toward returning ICU patients to the lives they had before their hospital stay. An essential resource for anyone who will be affected by illness—which is all of us—Ely’s “personal, passionate return to the ethical heart of the Hippocratic oath…[offers] meaningful, thought-provoking insight into the world of critical care” (Kirkus Reviews).

Fungi are unlike any other living thing—they almost magically unique. Welcome to this astonishing world. . .  Fungi can appear anywhere, from desert dunes to frozen tundra. They can invade our bodies and live between our toes or our floorboards.  They are unwelcome intruders or vastly expensive treats, and symbols of both death and eternal life. But despite their familiar presence, there's still much to learn about the eruption, growth, and decay of their secret, interconnected, world. Aliya Whiteley has always been in love with fungi—from her childhood taking blurry photographs of strange fungal eruptions on Exmoor to a career as a writer inspired by their surreal and alien beauty. This love for fungi is a love for life, from single-cell spores to the largest living organism on the planet; a story stretching from Aliya's lawn into orbit and back again via every continent. From fields, feasts and fairy rings to death caps, puffballs and ambrosia beetles, this is an intoxicating journey into the life of extraordinary organism, one that we have barely begun to understand.

The acclaimed chronicle of the regeneration of one family's traditional English farm NATIONAL BESTSELLER * Winner of the Wainwright Prize for Nature Writing * Named "Nature Book of the Year" by the Sunday Times * New York Times Editors' Choice * Shortlisted for the Orwell Prize and the Royal Society of Literature's Ondaatje Prize * A BEST BOOK OF THE YEAR: Sunday Times, Financial Times, New Statesman, Independent, Telegraph, Observer, and Daily Mail "Superbly written and deeply insightful, the book captivates the reader until the journey’s end.” — Wall Street Journal The New York Times bestselling author of The Shepherd’s Life profiles his family’s farm across three generations, revealing through this intimate lens the profound global transformation of agriculture and of the human relationship to the land. As a boy, James Rebanks's grandfather taught him to work the land the old way. Their family farm in England's Lake District hills was part of an ancient agricultural landscape: a patchwork of crops and meadows, of pastures grazed with livestock, and hedgerows teeming with wildlife. And yet, by the time James inherited the farm, it was barely recognizable. The men and women had vanished from the fields; the old stone barns had crumbled; the skies had emptied of birds and their wind-blown song. Hailed as "a brilliant, beautiful book" by the Sunday Times (London), Pastoral Song (published in the United Kingdom under the title English Pastoral) is the story of an inheritance: one that affects us all. It tells of how rural landscapes around the world were brought close to collapse, and the age-old rhythms of work, weather, community and wild things were lost. And yet this elegy from the northern fells is also a song of hope: of how, guided by the past, one farmer began to salvage a tiny corner of England that was now his, doing his best to restore the life that had vanished and to leave a legacy for the future. This is a book about what it means to have love and pride in a place, and how, against all the odds, it may still be possible to build a new pastoral: not a utopia, but somewhere decent for us all. [Published in the United Kingdom as English Pastoral.]

Steve Irwin meets David Attenborough in this jaw-dropping account of studying the world’s most venomous creatures. Venomologist Bryan Grieg Fry has one of the most dangerous jobs on earth: he works with its deadliest creatures. He’s been bitten by twenty-six venomous snakes, been stung by three stingrays, and survived a near-fatal scorpion sting while deep in the Amazon jungle. He’s received more than four hundred stitches and broken twenty-three bones, including breaking his back in three places, and had to learn how to walk again. But when you research only the venom you yourself have collected, the adventures—and danger—never stop. Imagine a three-week-long first date in Siberia catching venomous water shrews with the daughter of a Russian war hero; a wedding attended by Eastern European prime ministers and their machine-gun-wielding bodyguards and snakes; or leading a team to Antarctica that results in the discovery of four new species of venomous octopi. Bryan’s discoveries have radically reshaped views on venom evolution and contributed to the creation of venom-based life-saving medications. In pursuit of venom, he has traveled the world collecting samples from Indonesia to Mexico, Germany, and Brazil. He’s encountered venomous creatures of all kinds, including the Malaysian king cobra, the Komodo dragon, and the brush-footed trapdoor spider. Bryan recounts his lifelong passion for studying the world’s most venomous creatures in this outlandish, captivating memoir, where he and danger are never far apart.

In this fresh and engaging guide to chemistry, Dr. Kate Biberdorf, aka "Kate the Chemist," reveals the fascinating science we experience every day  Have you ever wondered what makes dough rise? Or how your morning coffee gives you that energy boost? Or why your shampoo is making your hair look greasy? The answer is chemistry. From the moment we wake up until the time we go to sleep (and even while we sleep), chemistry is at work—and it doesn't take a PhD in science to understand it.  Dr. Biberdorf has appeared on TV programs from the Today show to The Late Show with Stephen Colbert, lighting the world on fire and changing the face of chemistry as we know it. In It's Elemental, she demystifies the fundamental principles of the science that may have eluded you in high school and shows how chemistry comes alive in everything we do. With wry wit and infectious enthusiasm, this entertaining guide will ignite your passion for science and change the way you experience the world. Supplemental enhancement PDF accompanies the audiobook.

Grey’s Anatomy meets One L in this psychiatrist’s charming and poignant memoir about his residency at Harvard. Adam Stern was a student at a state medical school before being selected to train as a psychiatry resident at one of the most prestigious programs in the country. His new and initially intimidating classmates were high achievers from the Ivy League and other elite universities around the nation. Faculty raved about the group as though the residency program had won the lottery, nicknaming them “The Golden Class,” but would Stern ever prove that he belonged? In his memoir, Stern pulls back the curtain on the intense and emotionally challenging lessons he and his fellow doctors learned while studying the human condition, and ultimately, the value of connection. The narrative focuses on these residents, their growth as doctors, and the life choices they make as they try to survive their grueling four-year residency. Rich with drama, insight, and emotion, Stern shares engrossing stories of life on the psychiatric wards, as well as the group’s experiences as they grapple with impostor syndrome and learn about love and loss. Most importantly, as they study how to help distressed patients in search of a better life, they discover the meaning of failure and the preciousness of success.  Stern’s growth as a doctor, and as a man, have readers rooting for him and his patients, and ultimately find their own hearts fuller for having taken this journey with him.

The first major biography of the logician and mathematician whose incompleteness theorems helped launch a modern scientific revolution. Nearly a hundred years after its publication, Kurt Gödel's famous proof that every mathematical system must contain propositions that are true—yet never provable—continues to unsettle mathematics, philosophy, and computer science. Yet unlike Einstein, with whom he formed a warm and abiding friendship, Gödel has long escaped all but the most casual scrutiny of his life. An intimate portrait of the scientific and intellectual circles in prewar Vienna and a vivid re-creation of the early days of Princeton's Institute for Advanced Study, Journey to the Edge of Reason is the first biography to fully draw upon Gödel's voluminous letters and writings—including a never-before-transcribed shorthand diary of his most intimate thoughts—to explore his profound intellectual friendships, his moving relationship with his mother, his troubled yet devoted marriage, and the debilitating bouts of paranoia that ultimately took his life. It illuminates the mind-bending implications of Gödel's revolutionary ideas for philosophy, mathematics, artificial intelligence, and man's place in the cosmos.