“Perception of Doctors on Stem Cell Banking”

Presentation On a Research Project work of B. PHARMA Session 2011-2012
Submitted To: Dr. A. Mazumder Submitted By: Vertika Mishra

Stem cells: Are biological cells found in all multicellular organisms  Can divided (through mitosis) and differentiate into diverse specialized cell types  And can self-renew to produce more stem cells.

Introduction

 There are two broad types of stem cells: i. Embryonic stem cells, which are isolated from the inner cell mass of blastocysts. ii. Adult stem cells, which are found in various tissues.

Types of stem cells:-

Stem Cell Type

Description

Examples

Totipotent

Each cell can develop Cells from early (1-3 into a new individual days) embryos

Pluripotent

Cells can form any (over Some cells of blastocyst 200) cell types (5 to 14 days)

Multipotent

Cells differentiated, but Foetal tissue, cord blood, can form a number of and adult stem cells other tissues

Types of stem cells on cell level :-

1.Embryonic stem cells are harvested from the inner cell mass of the blastocyst seven to ten days after fertilization.

2. Fetal stem cells - are taken from the germ-line tissues that will make up the gonads of aborted fetuses.

3. Umbilical cord stem cells Umbilical cord blood contains stem cells similar to those found in bone marrow.

4. Placenta derived stem cells - up to ten times as many stem cells can be harvested from a placenta as from cord blood.

5. Adult stem cells - Many adult tissues contain stem cells that can be isolated.

Sources of stem Cell

To study the factors and properties to be considered while banking of stem cells. To study weather stem cell banking is feasible or not (through doctor’s point of view). To study the market conditions and potential markets for stem cell banking. To provide with useful recommendations based on the study. To come across the opinion of different doctors related to the stem cell banking. To study the future prospective of stem cell banking. To study the source of knowledge of stem cell banking. To study the feasibility of stem cell banking in market.

Objectives of the research project:-

• Obligatory asymmetric replication.

1. Self renewal

• Stochastic differentiation.

2. Potency definitions

• • • • •

1. Totipotent stem cells. 2. Pluripotent stem cells. 3. Multipotent stem cells. 4. Oligopotent stem cells. 5. Unipotent cells.

Properties of stem cells

1. Are you aware of stem cell banking?
2. What is the source of your knowledge about stem cell banking? 3. Are you in favour of prescribing stem cell banking? 4. For which given under would you like to prescribe to preserve stem cell? 5. What is the reason for choice of preserving stem cell? 6. Have any of your patients preserved their or their baby’s stem cell? 7. How many of your patients come on weekly basis for taking advice for preserving their or their baby stem cell? 8. Which company do you prefer or advice to patients for stem cell banking? 9. Are you satisfied by the services given by the company?

Questionnaire prepared for doctors

The perception of doctor towards favour of stem cell banking.

Companies recommended by doctors to patients.

Source of knowledge of stem cell banking

• http://en.wikipedia.org/wiki/Stem_cell • http://mycordblood.familycord.com/banking-cord-blood-and-cordtissue/ • http://www.stemcellresearchnews.net/ • http://en.wikipedia.org/wiki/Stem_cell_controversy • http://en.wikipedia.org/wiki/Cell_bank • http://www.cryobanksindia.com/ • http://www.lifecellinternational.com/ • http://www.webmd.com/alzheimers/news/20040708/future-of-stemcells • Tripathi K.D., Essential of medical Pharmacology, Fourth edition, Jaypee Medical Prakashan • Tuch BE (2006). "Stem cells—a clinical update". Australian Family Physician 35 (9): 719–21. PMID 16969445.

References