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Addison’s

Autoimmune (infection is nd MCC) the 2

Aneurysm, dissecting
HTN

Aortic aneurysm, abdominal and descending aorta Atherosclerosis

Aortic aneurysm, ascending

3° syphilis

Bacterial meningitis (adults)

Neisseria meningitidis

Bacterial meningitis (elderly)

Streptococcus pneumoniae

Bacterial meningitis (kids)
Haemophilus influenzae type B

Bacterial meningitis (newborns)

E. coli

Cancer asso w/ AIDS
Kaposi’s sarcoma

Congenital adrenal hyperplasia 21-hydroxylase deficiency

Cretinism
Iodine deficit/hypothyroidism

Cushing’s syndrome
Corticosteroid therapy MCC is excess ACTH secretion by pituitary)
nd (2

Death in CML
Blast crisis

Death in SLE
Lupus nephropathy

Dementia
Alzheimer’s MC is multi-infarct)
nd (2

DIC
Gram-negative sepsis, obstetric complications, cancer, burn trauma

Ejection click
Aortic/pulmonic stenosis

Food poisoning
S. aureus

Glomerulonephritis (adults)

IgA nephropathy (Berger’s disease)

Hematoma—epidural
Rupture of middle meningeal artery (arterial bleeding is fast)

Hematoma—subdural
Rupture of bridging veins (trauma; venous bleeding is slow)

Hemochromatosis
Multiple blood transfusions (can result in CHF and increased risk of hepatocellular carcinoma)

Hepatic cirrhosis
EtOH

Hepatocellular carcinoma
Cirrhotic liver (often asso w/ hepatitis B and C)

Holosystolic murmur
VSD, tricuspid regurgitation, mitral regurgitation

HTN, 2°
Renal disease

Hypoparathyroidism
Thyroidectomy

Hypopituitarism
Adenoma

Infection in blood transfusion

Hepatitis C

Infection in burn victims
Pseudomonas

Leukemia (adults)
AML

“Machine-like” murmur
PDA

Mental retardation
Down syndrome (fragile X nd MCC) is the 2

MI
Atherosclerosis

Mitral valve stenosis
Rheumatic heart disease

Myocarditis
Coxsackie B

Nephrotic syndrome (adults)

Membranous glomerulonephritis

Nephrotic syndrome (kids)
Minimal change disease (asso w/ infections/ vaccinations; Tx w/ corticosteroids)

Opening snap
Mitral stenosis

Osteomyelitis
S. aureus

Osteomyelitis in patients with sickle cell disease Salmonella

Osteomyelitis w/ IVDA
Pseudomonas

Pancreatitis (acute)
EtOH and gallstones

Pancreatitis (chronic)
EtOH (adults), cystic fibrosis (kids)

Peau d’orange
Carcinoma of the breast

PID
Neisseria gonorrhoeae (monoarticular arthritis)

Pneumonia (nosocomial)
Klebsiella

Pneumonia in cystic fibrosis, burn infection Pseudomonas aeruginosa

Preventable blindness
Chlamydia

Primary amenorrhea
Turner’s (XO)

Primary hyperaldosteronism

Adenoma of adrenal cortex

Primary hyperparathyroidism

Adenoma

Pulmonary hypertension
COPD

Right heart failure due to a pulmonary cause

Cor pulmonale

Right-sided heart failure
Left-sided heart failure

Sheehan’s syndrome
Postpartum pituitary infarction 2° to hemorrhage

SIADH
Small cell carcinoma of the lung

UTI
E. coli

UTI (young women)
E. Coli and Staphylococcus saprophyticus