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Universidad Cooperativa de Colombia- Seccional Magdalena Facultad de Ciencias de la Salud -Programa Ciências Básicas Médicas Programa Medicina- Área

Patología, III Semestre-Aprendizaje Basado en Problema (ABP)

•Caso 1-Hipertrofia del Miocardio •Caso 2-Hiperplasia Nodular de la Próstata

•Caso 3-Metaplasia Escamosa , Pelvis Renal
•Caso 4.-Metamorfosis Grasa Hepática •Caso 5. Atrofia de testículo

Caso 1. Hipertrofia Cardiaca

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Caso 2. Hiperplasia de Prostata .

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.This kidney was removed from another autopsy patient who had prostatic hyperplasia resulting in marked urinary retention and back-flow of urine from the bladder into the ureters and renal pelvis. This change in the kidney is called hydronephrosis. The increased pressure inside the renal pelvis resulted in dilation of the renal pelvis (1) and pressure atrophy of the cortex (2).

. although these are hard to appreciate at this low magnification.No – Pelvis Renal This is a low-power photomicrograph showing the full cortical and medullary thickness of the kidney.Caso 3. Metaplasia Escamosa. The cortex is markedly thin and has severe lesions of degeneration and atrophy. Note that there is a dilated calyx containing some red blood cells in the center of the section (arrow).

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Higado Graso This gross photograph of liver tissue illustrates the yellowish color of the liver parenchyma.Caso 4. The yellow color indicates high fat content in this tissue. . Compare this with the normal dark red color of liver.

A few more normal-appearing hepatocytes are present at the left portion of the slide (arrows). .This higher-power photomicrograph of the centrilobular area gives the appearance of fatty tissue. as indicated by many empty spaces. Very few normal liver cells can be seen in this slide.

. By using frozen sections the tissues do not have to be dehydrated through alcohol solutions and thus the fat does not get washed out.An oil red O stain for fat was performed on a frozen section of this liver tissue. The red droplets represent fat in the tissue which is typical of fatty degeneration in the liver.

Alcoholic hyalin is easily distinguished from red blood cells (3) that are also present in this section.This photomicrograph of the liver is from another patient with a history of alcohol use. . There are some clear vacuoles indicating fat droplets (1) and there are numerous red-staining granular deposits within the cytoplasm of hepatocytes (2)--this is alcoholic hyalin.

The proliferation of scar tissue between the liver lobules is the result of cirrhosis. connective tissue stains green (arrows) and hepatic parenchymal cells are red. . Note that many of the parenchymal cells have clear spaces indicating fatty degeneration.This is a low-power photomicrograph of liver stained with a trichrome stain. In this section.

The green color is due to the accumulation of bile pigment.This gross photograph of liver demonstrates severe nodular cirrhosis. Note the extensive scarring of the capsule and the nodular projections of tissue through the uncut capsule in this tissue. .

This is a cut surface of the same tissue seen in the previous slide. The paler-staining areas between the round nodules represent fibrous connective tissue. Note the marked nodular pattern. .

Caso 5. Atrofia Testicular .