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Muresan Lorena Pharmacy, II

TABLE OF CONTENTS  1-What is a diet pill  2-History  3-Contemporary anti-obesity drugs  4-Examples of pills  5-Do I Need a Prescription Weight Loss Drug?  6-Types of Prescription Weight Loss Drugs  7-Side effects  8-Biography .

or absorption of calories. weight regulation. . by either altering appetite.DIET PILLS  Anti-obesity medication or weight loss drugs are all pharmacological agents that reduce or control weight  These drugs alter one of the fundamental processes of the human body.

History The first described attempts at producing weight loss are those of Soranus of Ephesus. a Greek physician. and . massage. He prescribed elixirs of laxatives and purgatives. in the second century AD. as well as heat.

and thus are of limited usefulness for extremely obese patients. Some prescription weight loss drugs are stimulants. anti-obesity drugs can be a last resort.Contemporary anti-obesity drugs  Some patients find that diet and exercise is not a viable option. which are recommended only for short-term use. for these patients. who may need to reduce weight over months or years .

 Lorcaserin  Sibutramine  Rimonabant  Metformin .EXAMPLES  Only one anti-obesity medications orlistat (Xenical) is currently approved by the FDA for long term use.


While most side effects of prescription weight loss drugs are mild. As in other chronic conditions. such as diabetes or high blood pressure. serious complications have been reported. use of prescription drugs may be appropriate for some people. More on that below. .Do I Need a Prescription Weight Loss Drug?  Obesity often requires long-term treatment to promote and sustain weight loss.

One common prescription appetite suppressant is phentermine ." These drugs generally come in the form of tablets or extended-release capsules (pills that release medication over a long period of time).  One type of weight-loss medication is "appetite suppressants. most available weight loss drugs approved by the FDA are for short-term use. meaning a few weeks or months.Types of Prescription Weight Loss Drugs  Currently. Appetite suppressants can be obtained by a doctor's prescription or purchased over the counter.

and flatulence. fen-phen being a famous example. and as a result may cause oily spotting bowel movements (steatorrhea). palpitations. and flatulence. stimulants carry a risk of high blood pressure. orlistat.Side effects  Some anti-obesity drugs have severe or life- threatening side effects. restlessness. and insomnia.  Another drug. agitation. faster heart rate. closed-angle glaucoma. designed for patients with Type 2 diabetes. oily stools. is Acarbose which partially blocks absorption of carbohydrates in the small intestine. drug addiction. In general. These side effects are often associated with their mechanism of action. and produces similar side effects including stomach pain. stomach pain. . blocks absorption of dietary fats. A similar medication.



. forPatientsandProviders/ucm213038.  WIN – Publication – Prescription Medications for the Treatment of  Cooke D. assessment and management of overweight and obesity in adults and children.fda. National Institutes of Health. Clinical guideline 43: Obesity: The prevention. "The obesity pipeline: current strategies in the development of anti-obesity drugs".htm  http://teacherlink. Obesity". Archived from the original on 13 January 2009. identification.pdf . Nature reviews. Retrieved 14 January 2009. National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).edu/nmsmithpages/Personal/Diabetes%20Care %20Reference%20Materials/Diabetes%20Medications%20Metformin. London. Bloom S (2006).Biography  National Institute for Health and Clinical Excellence. Drug discovery 5 (11): 919–31.  http://www.ed.