GROUP D STREPTOCOCCUS

Enterococcus faecalis &S. bovis

Dr.Aravind

• E. faecalis (Name-Derivation: feces)
• S.bovis (bovine)

• Part of the GIT normal flora
• Gram-positive cocci in pairs or short chains

• Catalase negative
• Lancefield Group D specific cell wall carbohydrate teichoic acid antigen

• Facultative anaerobes
• Halotolerant and Bile resistant
Dr.Aravind

• Epidemiology:

• Endogenous in large intestine and animals
• Food transmission • Nosocomial

• Urinary or intravascular catheterization

Dr.Aravind

• Pathogenesis: • R plasmid • No potent virulenant factors
• Colonization & secretory factors
• Fibrinolytic • carbohydrate factors - adherence • Bacteriocins: Inhibit competitive bacteria

• GIT colonization • UTI

bacteremia

Subacute endocarditis

Dr.Aravind

Clinical conditions:
• Urinary tract infections • GIT diseases • Nosocomial →Sub acute bacterial endocarditis • S.Bovis →associated with colon cancer • Meningitis
Dr.Aravind

Clinical Conditions
Meningitis Sub acute endocarditis 1. Slow pace 2. Anemia 3. Roth’s spots 4. Splinter hemorrhages 5. Murmurs 6. Emboli 7. Osler’s nodes. GIT infections Dysentery, abscess etc Entry: Endogenous, food born and catheters UTI Dysuria, increased frequency

Dr.Aravind

Roth’s spots Splinter hemorrhages Osler’s nodes

Dr.Aravind

Diagnosis:  Resemble S. pneumoniae in Gram stains  Growth
 Large white colonies  E. Faecalis → blood agar with 40% bile & 6.5% Nacl  S.bovis→ blood agar with 40% bile and not with 6.5% Nacl

 Hydrolysis of esculin to esculetin on BEA media →Black discoloration  Resistance to optochin  PYR +
Dr.Aravind

Treatment:  Resistance R Plasmid  Ampicillin, Vancomycin, Pristinomycin

Dr.Aravind

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