Ingredients in Alex

• • • • • Dextromethorphan Hydrobromide Guaiphenesin Phenylephrine Hydrochloride Chlorpheniramine maleate Paracetamol

Dextromethorphan Hydrobromide (DMR)
• Non - narcotic cough suppressant (anti tussive). • Acts centrally on cough centre, (Medulla) and elevates the threshold for coughing. • Equipotent to codeine in depressing cough reflex.

• Average dose is 10 to 30 mg 3 to 6 times daily.
• Exerts effect within 15-30 minutes after oral administration. • Duration of action is 5-6 hours.
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Favorable Features of Dextromethorphan Hydrobromide
• Equipotent antitussive to Codeine, Pholcodiene which are narcotic. • No addictive properties. • Does not cause CNS depression nor it affects respiratory rate. • Does not cause drowsiness, constipation unlike codeine. • Is safe & effective.

Guaiphenesin • Most commonly used expectorant. . this helps to liquefy the thick mucus. • Though not a cough suppressant reduces the intensity and frequency of dry or productive cough. • Increases the output of respiratory tract fluids.

• Drug is eliminated primarily as metabolites in urine (8086%). . • Half-life is approximately 2-3 hrs. • Phenylephrine effects its vasoconstrictor activity by releasing noradrenaline from sympathetic nerve endings and from direct stimulation of (alpha)-adreno receptors in blood vessels.Phenylephrine Hydrochloride • It is oral nasal decongestant.

Phenylephrine Hydrochloride Stimulates Symphathetic adrenergic nerve endings Norephinephrine Alpha & Beta receptors Mode of Action Vasoconstriction Acts as Nasal Decongestant .

15mg/kg mg every 4 hours Sales Training .Dosage Phenylephrine Hydrochloride • Adult: 10 mg every 4 hours • Children: 0.

• Rapidly and completely absorbed from GI tract. • Peak plasma concentration reaches within 30-60 minutes • Plasma Half-life is about 2 hours after therapeutic dose. • Less toxicity and most widely preferred. .Paracetamol • Effective alternative to aspirin as analgesic & antipyretic.

• One of the most potent antihistamines. Sales Training . • Prevents histamine from dilating capillaries that causes oedema of respiratory mucosa. itching of eyes.Chlorpheniramine Maleate • H1 receptor antagonist. • Effective in relatively low doses (2mg-4mg). • One of the most effective and least toxic antihistamine. nose & throat). • Promptly relieves symptoms in Rhinitis (sneezing.

• For those aged 1 to 5 years 1 to 2 mg three times daily.Dosage Chlorpheniramine Maleate • In children upto 1 year dose is 1mg twice daily. • For 6 to 12 years. 2 to 4 mg 3 or 4 times daily. Sales Training .

s.Alex Cough Lozenges Composition Each Lozenge contains : • Dextromethorphan Hydrobromide I. 5 mg • Sugar base q.P. Sales Training .

Sales Training .Alex Cough Lozenges Profile • Unique product. • Word 'Lozenges' is from old French word 'Lauze' meaning a flat stone. was introduced for the first time in India.

Sales Training .Alex Cough Lozenges Profile • The medical definition of Lozenges is tablet containing medication in flavoured and sweetened base. • Designed for local treatment of throat by slow & steady release of the medicine in the mouth.

• Promote mucus secretion : an important defense mechanism of respiratory tract.Actions of Alex Cough Lozenges • Demulcent Action base of Lozenges offer protective barrier over inflamed mucous membrane.unlike with syrup preparations. • Provides longer contact time with mucous membrane . Sales Training .

Sales Training . • When antitussive action & demulcent action is required. irritative cough.Alex Cough Lozenges Indications • Mainly used for non-productive.

Alex Cough Lozenges Dosage Adults and children above 12 years Children 6 to 12 years 4 to 6 years < 4 years : 1-2 Lozenges every 68hours. As directed by Physician. Not recommended. : : : Sales Training 1 Lozenge 3-4 times a day. .

Available in strip of 10s. 10 strips are in an outer carton. Sales Training .

s.Alex Cough Formula Composition Each 5 ml contains : • Guaiphenesin • Dextromethorphan Hydrobromide • Phenylephrine 100 mg 10 mg 5 mg • Chlorpheniramine maleate • Flavoured base Sales Training 4 mg q. .

to tackle various types of cough and associated symptoms.Alex Cough Formula Indications Recommended in cases of Productive Cough and cold due to LRTI. i. .e.

Not recommended. Sales Training . 1 year to 5 years . Less than 1 yr.5 ml) 3-4 times a day.Alex Cough Formula Dosage Adults & Children: Above 12 years teaspoonful(10 ml) 3-4 times a day. 2 6 years to 11 years.1/2 teaspoonful(2.1 teaspoonful(5 ml) 3-4 times a day.

Sales Training .Alex Cough Formula Precautions Patients should be advised to abstain from taking alcohol or other CNS depressants concomitantly.

Sales Training .Available in 50 & 100 ml pet bottles.

.Alex Sugar Free Syrup Rationale Ideal for . • Diabetic patients • Calorie Conscious patients • Patients with dental problems Sales Training ..

Alex Sugar Free Syrup Choice of Sweetener ALEX Sugar Free is sweet and palatable: Due to SORBITOL (70% w/w) in place of sugar. Sales Training .

Available in 50 ml pet bottle Sales Training .

5mg q.s .Alex-P Syrup Composition Each 5ml contains : • Paracetamol • Dextromethorphan Hydrobromide • Phenylephrine Hydrochloride • Chlorpheniramine Maleate • Flavoured base Sales Training 170mg 5mg 2.5mg 1.

Sales Training . fever. pharyngitis. upper respiratory tract infections and sinusitis.Alex-P Syrup Indications • Indicated in the treatment of cold. and pain relief in rhinitis.

6 years to 11 years.Not recommended.1/2 teaspoonful(2. 1 year to 5 years .1 teaspoonful(5 ml) 3-4 times a day. Less than 1 yr. Sales Training .Alex-P Syrup Dosage Adults & Children: Above 12 years .2 teaspoonful(10 ml) 3-4 times a day.5 ml) 3-4 times a day.

Sales Training .Available in bottle of 60 ml pet bottle with a measuring cap.

Sales Training .s.Alex Paediatric Drops Composition Each ml contains : • Phenylephrine Hydrochloride 2.5 mg • Chlorpheniramine Maleate • Flavoured base 2 mg q.

• Both together clear a blocked nose.Alex Paediatric Drops Rationale • Phenylephrine is most frequently used decongestants. Sales Training . equipotent to ephedrine. with less CNS stimulation. • Chlorpheniramine Maleate possesses good antihistaminic activity with less sedative and anticholinergic effects.

Sales Training . running nose. stuffy nose. sneezing.Alex Paediatric Drops Indications Recommended for the symptomatic relief of colds the and nose allergic or symptoms throat and including itchy. itching of water eyes.

12 months hours • 12 .Alex Paediatric Drops Dosage • 4 .24 months hours 0.25 ml every 4 to 6 Sales Training .6 ml every 4 to 6 1.

Available in 15 ml bottle with dropper. Sales Training .

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