The correlation between Rheumatic Fever and Endocarditis

By : Diaz Rahmadi 030.08.082

evidence suggests that there has been little if any decline in the occurrence of RHD over the past few decades. The high frequency of RHD in the developing world necessitates aggressive prevention and control measures .6/1000. causing morbidity and mortality among both children and adults. Although little longitudinal data are available.Background • Rheumatic heart disease (RHD) continues to be a common health problem in the developing world. Recent reports from the developing world have documented rheumatic fever (RF) incidence rates as high as 206/100 000 and RHD prevalence rates as high as 18.

Definition • Rheumatic Heart Disease is a disease characterized by damage to the heart valves caused by an attack of acute rheumatic fever carditis who repeatedly happen • Rheumatic fever is a clinical syndrome as a result of beta-streptococcal infection hemolyticus group A. korea minor. subcutaneous nodules and erythema marginatum. carditis. . with one or more major symptoms of acute polyarthritis migrans.

In the old growth or dead germs gram positive nature will be lost and become gram-negative . Will be longer chains in liquid media than on solid media. lined up like a chain composed. Chain length varies and is determined largely by environmental factors. sometimes resembling sticks.Streptococcus B hemolyticus group A • • • • FAMILI : Streptococcaceae GENUS : Streptococcus SPESIES : Streptococcus pyogenes Germs are round or oval.

Rheumatic Fever Inflammatory disease • Complication • Strep throat caused by Streptococcus group A Epidemiology • Most common in 5 to 15 years old • Common in developping nations Symptoms • Permanent damage to the heart • Treatments can reduce tissue damage .

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an infection or other medical condition. chills. attach abnormal heart valve • Offending organism may enter your bloodstream through : common activities. travel to your heart. persistent cough. night sweats • Shortness of breath.Endocarditis Is an infection of the inner lining of your heart ( endocardium) • Occurs when bacteria from another part of body attached to damaged area in your heart • Uncommon in people with healthy heart Sign and Symptoms • Fever. dental procedures . fatigue. swelling in your feets Causes • Germs enter bloodstream. a new or change heart murmur. paleness. catheters o needles.

How rheumatic fever and endocarditis correlated ? .

Ethnic 4. Nutritional State • Environmental factors 1. Weather . Poor socio-economic circumstances 2. Age 5. Genetic factors 2. Sex 3.Predisposing factors • Individual Factors 1. Climate and geography 3.

. but ampicillin and amoxicillin are equally effective.Prevention • Oral (PO) penicillin V remains the drug of choice for treatment of GABHS pharyngitis.

and is triggered by a reaction to the streptococcal bacteria in strep throat. Rheumatic heart disease ends up affecting about half the people who have rheumatic fever with carditis. body reacts to this.Conclusion • In conclucion. Most of the time. the occurrence of endocarditis in patients with rheumatic fever caused by germs sterptococcus beta hemolitycus group that causes strep throat. • Rather. because the antigens of the bacteria streptococcus beta hemolitycus almost similar to those in the heart. Cardiac involvement in rheumatic fever can be on any network component. rheumatic heart disease is diagnosed 10 to 20 years after being "triggered" by acute rheumatic fever . the endocarditis in rheumatic fever is caused by an autoimmune process that affects many parts of the body in addition to the heart. by producing antibodies.

Available at : http://medicastore. Available at : http://heartdisease.about. Sexton D. Eisenberg. October 4 2008. Mumpuni S.html#CausesandRiskFactorsofEndocarditis .D.wordpress. Bryant P.org/content/120/3/243. Available at : http://wwwmikrobia. Mark J. Available at : http://www. Guilherme L. Available at : http://emedicine. August 4 2010.com/ency/68/72/main. Accessed on July 8 2011 • .htm .html .wordpress. Accessed on July 8 2011 Endocarditis. Accessed on July 8 2011 Infectious endocarditis . August 13 2008. March 25 2011.com/2008/03/streptococcus.annals.org/content/14/1/122. Mukti A.M.oxfordjournals. Available at : http://usebrains.com/article/891897-overview#a0104 . Availabel at : http://www.medscape. Margaret J.com/penyakit/961/Demam_Rematik. Accessed on July 8 2011 Causes and risk factors of Endocarditis.short Accessed on July 10 2011 Rheumatic Heart Disease in developing country.Refferences • • • • • • • • • • Rheumatic fever in emergency medicine. M. Pahlevi R.com/health/endocarditis/DS00409 . Fogoros.full . Accessed on July 8 2011 Rheumatic Fever. Available at : http://eurheartj. Available at : http://www.A. Richard N.files.medscape.healthscout.J.pdf . Accessed on July 8 2011 Acute Rheumatic Fever.July 28 2001.A. January 21 2010. July 10 2003. Available at : http://emedicine.mayoclinic.S. April 27 2008. May 17 2008.com/od/heartvalvedisease/a/Infectious_endocarditis.com/2008/10/04/demam-rematik-akut/ .com/article/808945-overview Accessed on July 8 2011 Rheumatic Heart Disease in the developing world. Accessed on July 8 2011 Streptococcus Beta Hemolitycus Group A . Accessed on July 8 2011 Rheumatic Heart Disease. February 3 2004.