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James Barraclough

Respiratory System Transport of Oxygen








Using the equipment,
build a model of the lungs:
Play doh
2l bottle
Scissors
Tubing
Tape
Plastic bag
Balloons








Objectives: by the end of the lesson, learners will
be able to:
Describe the transport of oxygen & the
oxyhaemoglobin dissociation curve
Describe gas exchange at the muscles & tissues
Define minute ventilation
Describe ventilation during exercise

Complete worksheet Part 1

15 minutes & feedback to class


ANSWERS
c.97% of O2 carried by red blood cells combined with haemoglobin (iron-based protein)

Haemoglobin + Oxygen = Oxyhaemoglobin
Hb O2 HbO2

Each Hb molecule can combine with 4 molecules of O2 = c.1.34ml
Concentration of Hb in blood = c. 15g/100ml
Therefore 100ml blood can transport up to 20 ml of O2
(1.34 x 15)
Remaining 3% of O2 carried in blood plasma
Individual pressure exerted by Oxygen in a mixture of gases
Decreases
Decreases
Acidity (see next slide for pH scale)
CO2
Temperature
Bohr
Right
Fall in pO2; increase in blood/muscle temperature; increase in pCO2 in muscle; fall in pH
from production of lactic acid
Bohr shift; at rest; during exercise; post exercise (see slide 8 for description)
http://www.youtube.com/watch?v=Qrvrs6RXxwY




Complete worksheet Part 2

15 minutes & feedback to class


Arteries
Gradient
Capillary
Due to high pCO2 in tissues & low pCO2 in arterial
blood CO2 moves in opposite direction
Myoglobin
Mitochondria
Endurance athlete e.g. Mo Farah, Paula Radcliffe
Myoglobin
Acts as O2 reserve so O2 stored for when needed
Arterial- venous oxygen difference (a- VO2 diff.)
25%; 85%
https://www.youtube.com/watch?v=J0442YCxpa8


Complete worksheet Part 3

10 minutes & feedback to class


Volume of air inspired OR expired (same amount)
500ml OR c.7ml/kg of body weight
c.350ml
Remains in dead space i.e. Nose, throat & trachea
Volume of air inspired/expired in 1 minute
Tidal volume x frequency of breaths (VE = TV x f)
12 15 breaths per minute
500ml x 15 = 7500ml/min OR 7.5L/min


Complete worksheet Part 4

10 minutes & feedback to class


Endurance
Anticipatory rise
Release of adrenaline/noradrenaline stimulating
respiratory control centre
Steady state
Oxygen; carbon dioxide
Maximum amount of O2 taken in, transported &
used in 1 minute
Lactic acid
Vital capacity =maximum amount of air a
person can expel from lungs after
maximum inhalation
Residual volume = air still remaining in lungs
after most forcible expiration possible



WWTBAM

Mind map


Respiratory complications
Impact of smoking
Adaptive responses to training