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VARICELLA

ZOSTER
CASE
Name :Mr. A.S.
Sex : Man
Age : 15 Years Old
Job : Unemployed
Address : Jerutallasa St., Jeneponto County
Status : Unmarried
Religion : Islam
Eye diagnosis :
Diagnosis : Varicella Zoster
ANAMNESIS

PHYSICAL EXAMINATION
Blood Pressure : mmHg
Heart Rate : x/mnt
Respiratory rate : x/mnt
Temperature : Afebris
Head : Anemis : -/-
Ikterus : -/-
Cyanosis : -/-

Cont.
Thorax : vesiculer, Wheezing (-), Ronchi (-)
Abdomen : Normal
Extremities : Normal, no sign of Pretibial
Oedema in lower extremities.
Limphe : No sign of limphoma, palpable pain
(-)
STATUS DERMATOLOGIST
Regio : Regio Generalisata
Effloresensi : Papul, Pustul,
Vesicle, Crusta,
Eruption, and
Hiperpigmented
(polimorf lesion)
Regio :
Effloresensi :
regio : Coli
Effloresensi : (1) vesicel, (2) krusta
Regio : lower and upper extremities
Effloresensi :
Diagnostic Examination
Laboratory Findings
WBC : 7,5 x 10
3
/mm
3

RBC : 4,8 x 10
6
/mm
3

HGB : 13,8 g/dL
HCT : 41,7 %
PLT : 406 x 10
3
/ mm
3

SGOT : 24 U/L
SGPT : 17 U/L

Eye Therapy

Therapy
Dermatology:
Antiviral : Aciclovyr 5 x 400mg ( 7 days )
Antihistamin : Interhistin 50mg 3 x 1
Salisil talk
Fuson cream

Definition
Varicella, commonly known as
chickenpox, is the primary infection
with the VZV.
Varicella is characterized by a
vesicular eruption consisting of
delicate teardrop vesicles on an
erythematous base.

ETIOLOGI VARICELLA ZOOSTER
VIRUS

Lipid envelope surrounding nucleocapsid
with icosahedral symmetry

Total diameter of approximately 150200


nm

Centrally located double-strand DNA with a


molecular weight of 80 million

Epidemiology
Varicella is distrubated worldwide
Since introduction of varicella vaccine
in 1995, incidence of varicella has
decreased as vaccination coverage has
increased.
Prior to 1995, 34 million cases in the
United States annually.

Patogenesis
VZV is thought to enter through mucosa of upper
respiratory tract and oropharynx.
Local Replication primary viremia
VZV replicates in cells of RES with subsequent
second- ary viremia and dissemination to skin
and mucous membranes.
VZV travel down to sensory nerve
Initial dermatom pain and skin lession
EFFLORESENCE OF
VARICELLA
Polimorf Lesion in varicella patient
CLINICAL FINDING
Mild febris
Effloresence : Vesicle Tears drop-like spreading from body
to upper and lower extrimities centrifugally
Itchiness of the whole body.
May infect upper respiratory tract and mucosa of the
mouth


DIAGNOSE
Clinical Feature
Tzanck Test (Datia cell with
multiple nucleus)
TREATMENT
Antiviral : Aciclovyr 5 x 400mg ( 7 days )
Antihistamin : Interhistin 50mg 3 x 1
Salisil talk
Fuson cream

DIFFERENTIAL DIAGNOSE
VARIOLA HERPES ZOSTER

PREVENTION
Vaccination at the age of 12 months and above and
revaccination at the age of 4 to 6 years old. via
subcutaneous injection 0.5ml at the age 12 months till 12
years old.
If vaccination is given at the age above 12 years old with
the same dosage, then revaccination 4 to 8 weeks. Then
antibody will appear in 3 to 6 days later
COMPLICATION
Encephalitis
Pneumonia
Glomerulonephritis
Hepatitis
Keratitis
Conjunctivitis, etc
PROGNOSIS
A better hygiene will result a better prognosis.